COMPOSITES SCIENCE AND TECHNOLOGY
·
2022
·
IF 9.879
Xiaohui Guo,Yuanfang Luo,Lijuan Chen,Bowen Zhang,Yongjun Chen,Demin Jia
To achieve simultaneous environment protecting, high-efficiency rubber antioxidant is still an enormous and long-term challenge in green rubber industry. Hence, a novel biomass antioxidant (denoted as silica-s-TP) was obtained by silica supported with green tea polyphenols exhibited prominent anti-aging functionality. Silica-s-TP hybrid particles were uniformly dispersed in rubber matrix with remarkable interfacial interaction , and the high-efficiency free radical capturing activity was stem from the construction of polyphenol structure on silica surface. Therefore, silica-s-TP brought to simultaneously enhance the performance of anti-aging property of SBR composites and surpass the achievements of the commercial antioxidants. Interesting, the biomass antioxidant silica-s-TP exhibited remarkable free radical-scavenging activities and stability in SBR matrix than the TP directly added in SBR matrix, due to the chemical anchor TP on silica surface. Such clay surface treatment technology with natural antioxidant may also bring to a new path for the preparation of green and eco-friendly functionalization rubber additives.
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RSC Advances
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2022
·Vol. 12
·期 5
·3157-3164
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IF 4.036
Yi Xiao,Guofang Wang,Haomin Yi,Suhua Chen,Qinyu Wu,Siyi Zhang,Kexin Deng,Simeng Zhang,Zi-Qi Shi,Xiaoping Yang
Ru(bpy)3Cl2/TPrA is a prominent and widely used ECL system in analytical science. However, the co-reactant TPrA restricts the variety of applications because of its toxicity, volatility, and high cost. Here, we use arginine (Arg) as an alternative co-reactant for Ru(bpy)32+ by taking advantage of its low cost, non-toxicity, and biocompatibility. The mechanism of the Ru(bpy)32+/Arg system is that the deprotonated Arg can react with Ru(bpy)32+ to release emission. The similarity between the Ru(bpy)32+/Arg, Ru(bpy)32+/TPrA, and Ru(bpy)32+/DBAE systems demonstrates that Arg can be used as an alternative co-reactant for Ru(bpy)32+ ECL. As a proof of concept, we achieve an excellent performance for acetaminophen (Ace) detection based on the specificity of Arg and Ace, with excellent linearity, low detection limits, and good recoveries. This work is promising to expand the scope of the Ru(bpy)32+/Arg system and move forward their applications in bioassays.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Hailan Qin,Jingyu Sun,Dongsheng Xia,Haiming Xu,Qilin Yu,Yi Zheng,Yintao Shi
Boosting nonradical ( 1 O 2 , e − and h + ) process to enhance the selective degradation for electrophilicity contaminants is an ingenious strategy. Herein, BiOI/BiOCl heterojunction with rational interface oxygen vacancies (IOVs) concentration was successfully synthesized by ultrasonic method. Moreover, multi-characterization and interference experimental unveiled that the appropriate IOVs concentration can not only effectively reduce the transport resistance of photo-induced carriers but also boost the nonradical process. Thus, BOC-5 can remove 84% (20 mg/L) tetracycline hydrochloride (TC-HCl) in 1 h and present wonderful insecticidal performance for rotifers. Simultaneously, the quantitative methods of IOVs concentration, the contribution of the active species to the catalytic performance and the contribution of different 1 O 2 source to the total 1 O 2 were established for the first time. Furthermore, the structure–activity relationship between the IOVs concentration and the catalytic properties was firstly constructed. This work provides an inventive idea to purify water pollutants and disinfestation by boost nonradical process via interface defect engineering.
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CANADIAN JOURNAL OF CHEMICAL ENGINEERING
·
2022
·Vol. 101
·期 1
·354-367
·
IF 2.5
Yun Liu,Xiaopan Jiao,Fuli Zhang,Daojian Cheng,Wensheng Qin
Supported non-noble metal catalysts for the selective oxidation of furfural into high-value chemicals have attracted considerable attention. Herein, an atom-level-isolated, cobalt-catalyst-supported N-doped carbon (Co SAs-N@C) was synthesized through a metal cobalt–tannic acid coordination assembly strategy. The obtained Co SAs-N@C with 7.68 wt% of Co content was qualitatively and quantitatively characterized by X-ray diffraction, X-ray photoelectron spectroscopy, high-resolution transmission electron microscopy, high-angle annular dark-field scanning transmission electron microscopy, inductively coupled plasma optical emission spectrometer, and X-ray absorption fine structure techniques. From the structural properties, potassium thiocyanate poisoning, and acid leaching, it was found that the atomic-dispersed CoNx species of the catalyst acts as the active site and plays a vital role in its highly effective oxidative esterification activity. The catalytic mechanism of this reaction is involved in radical oxidation, as confirmed by electron paramagnetic resonance spectra. The density functional theory calculations revealed that the reaction pathway proceeds as a hemiacetal pathway. Interestingly, the Co SAs-N@C catalyst also showed satisfactory catalytic activity for the aerobic oxidation of furfural. Unexpectedly, the Co SAs-N@C catalyst still possessed excellent stability and recyclability without loss of activity after five reuses.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2022
·Vol. 20
·期 1
·1-15
·
IF 9.429
Du Bin,Zheng Mei,Ma Huizhen,Huang Jingshu,Jiao Qingqing,Bai Yimeng,Zhao Mengmeng,Zhou Jie
Multidrug resistance is still a major obstacle to cancer treatment. The most studies are to inhibit the activity of the drug transporter P-glycoprotein (P-gp), but the effect is not ideal. Herein, a nanosystem was built based on cascade catalytic consumption of cholesterol. Cholesterol oxidase (natural enzyme, COD) was immobilized on the carrier (NH2-MIL-88B, MOF) through amide reaction, COD catalyzed the consumption of cholesterol, the reaction product H2O2 was further produced by the MOF with its peroxidase-like activity to produce hydroxyl radicals (•OH) with killing effect. Due to the high expression of CD44 receptor on the surface of tumor cells, we encapsulated chondroitin sulfate gel shell (CS-shell) with CD44 targeting and apoptosis promoting effect on the surface of DOX@MOF-COD nanoparticles, which can accurately and efficiently deliver the drugs to the tumor site and improve the effect of reversing drug resistance. Taking drug-resistant cell membrane as "breakthrough", this paper will provide a new idea for reversing multidrug resistance of tumor.Graphical Abstract
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Polymers
·
2022
·Vol. 14
·期 9
·1679
·
IF 4.967
Hongcai Wang,Xiuqiong Chen,Yanshi Wen,Dongze Li,Xiuying Sun,Zhaowen Liu,Huiqiong Yan,Qiang Lin
Oxidized sodium alginate (OSA) is selected as an appropriate material to be extensively applied in regenerative medicine, 3D-printed/composite scaffolds, and tissue engineering for its excellent physicochemical properties and biodegradability. However, few literatures have systematically investigated the structure and properties of the resultant OSA and the effect of the oxidation degree (OD) of alginate on its biodegradability and gelation ability. Herein, we used NaIO4as the oxidant to oxidize adjacent hydroxyl groups at the C-2 and C-3 positions on alginate uronic acid monomer to obtain OSA with various ODs. The structure and physicochemical properties of OSA were evaluated by Fourier transform infrared spectroscopy (FT-IR),1H nuclear magnetic resonance (1H NMR), X-ray Photoelectron Spectroscopy (XPS), X-ray Diffraction (XRD), and thermogravimetric analysis (TGA). At the same time, gel permeation chromatography (GPC) and a rheometer were used to determine the hydrogel-forming ability and biodegradation performance of OSA. The results showed that the two adjacent hydroxyl groups of alginate uronic acid units were successfully oxidized to form the aldehyde groups; as the amount of NaIO4increased, the OD of OSA gradually increased, the molecular weight decreased, the gelation ability continued to weaken, and degradation performance obviously rose. It is shown that OSA with various ODs could be prepared by regulating the molar ratio of NaIO4and sodium alginate (SA), which could greatly broaden the application of OSA-based hydrogel in tissue engineering, controlled drug release, 3D printing, and the biomedical field.Keywords:oxidized sodium alginate;oxidation degree;biodegradation gelation ability;rheological properties
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
·
IF 5.518
Yanning Zheng,Dapeng Xu,Lixia Sun,Junrong Ji,Jianhua Sun,Zhangfa Tong,Lingyi Qin,Youquan Zhang,Jiangxue Luo,Dankui Liao
The catalytic synergy of different nanomaterials is a potential technique used to develop a highly active and stable nanozyme . Here, magnetite on nitrogen-doped hollow carbon sphere (Fe 3 O 4 /N-HCS) composites were prepared through solvent thermal method and exhibited excellent oxidase and peroxidase-like catalytic activity under different pH levels. The dual enzyme-like catalyzed reaction of Fe 3 O 4 /N-HCS conformed to the typical Michaelis–Menten kinetics, and Fe 3 O 4 /N-HCS had a strong affinity for substrate 3,3′,5,5′-tetramethylbenzidine (TMB) with H 2 O 2 . The remarkable performance of the composites was achieved by the synergistic effect of Fe 3 O 4 and N-doped activated graphite carbon, which accelerated the formation of O 2 •- and •OH during the dual enzyme-like catalytic reaction . Furthermore, an effective colorimetric glutathione (GSH) sensor with a wide linear range from 0.02 µM to 250 µM and a detection limit as low as 9.3 nM was constructed based on the superior peroxidase-like activity of Fe 3 O 4 /N-HCS. The convenient colorimetric sensor monitored the content of GSH in the serum of mice, and the detection results were satisfactory, with a recovery of 96–103% and an RSD between 0.80% and 3.30%. This study discussed the internal mechanism of Fe 3 O 4 /N-HCS nanozyme and developed an efficient method for GSH detection to expand nanozyme application in bioanalysis .
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FOOD CHEMISTRY
·
2022
·
IF 9.231
Hao Chen,Yuzhe Huang,Cancan Zhou,Tenglong Xu,Xinyang Chen,Qianzhen Wu,Kunfeng Zhang,Yong Li,Daxiang Li,Yan Chen
In this study, the changes of structure and bioactivity of polysaccharides from large leaf yellow tea (LYTP) were investigated under ultra-high pressure (UHP). Native yellow tea polysaccharide were treatmented with ultra-high pressure (200, 400 and 600 MPa) for 5 min to yield yellow tea polysaccharide including 200 MPa-LYTP, 400 MPa-LYTP and 600 MPa-LYTP. It was found that the monosaccharide composition of LYTP changed significantly after the ultra-high pressure treatment. The molecular weight (Mw) of 200 MPa-LYTP (from 563.6 to 11.7 kDa), 400 MPa-LYTP (from 372.2 to 11.8 kDa) and 600 MPa-LYTP (from 344 to 11.6 kDa) sharply decreased upon ultra-high pressure treatment compared with LYTP (771.5 kDa), coincidentally particle size was also significantly reduced for 200 MPa-LYTP (23.2 %), 400 MPa-LYTP (40.2 %) and 600 MPa-LYTP (25.9 %). The results of the scanning electron microscope showed that ultra-high pressure also changed the surface and spatial morphology of LYTP. LYTP after ultra-high pressure treatment (UHP-LYTP) could further ameliorate alcohol-induced liver injury in mice. In addition, UHP treatment can more efficiently remove protein than the Sevages method. With the gradual removal of protein, its hepatoprotective effect increased. These findings demonstrated that UHP treatment could change the primary structure and spatial structure of LYTP, increase the content of acidic polysaccharides, and improve its bioactivity.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2022
·Vol. 20
·期 1
·1-20
·
IF 9.429
Chen Minjiang,Li Jie,Shu Gaofeng,Shen Lin,Qiao Enqi,Zhang Nannan,Fang Shiji,Chen Xiaoxiao,Zhao Zhongwei,Tu Jianfei,Song Jingjing,Du Yongzhong,Ji Jiansong
Transcatheter arterial chemoembolization (TACE) is one of the main palliative therapies for advanced hepatocellular carcinoma (HCC), which is also regarded as a promising therapeutic strategy for cancer treatment. However, drug-loaded microspheres (DLMs), as commonly used clinical chemoembolization drugs, still have the problems of uneven particle size and unstable therapeutic efficacy. Herein, gelatin was used as the wall material of the microspheres, and homogenous gelatin microspheres co-loaded with adriamycin and Fe 3 O 4 nanoparticles (ADM/Fe 3 O 4 -MS) were further prepared by a high-voltage electrospray technology. The introduction of Fe 3 O 4 nanoparticles into DLMs not only provided excellent T2-weighted magnetic resonance imaging (MRI) properties, but also improved the anti-tumor effectiveness under microwave-induced hyperthermia. The results showed that ADM/Fe 3 O 4 -MS plus microwave irradiation had significantly better antitumor efficacy than the other types of microspheres at both cell and animal levels. Our study further confirmed that ferroptosis was involved in the anti-tumor process of ADM/Fe 3 O 4 -MS plus microwave irradiation, and ferroptosis marker GPX4 was significantly decreased and ACSL4 was significantly increased, and ferroptosis inhibitors could reverse the tumor cell killing effect caused by ADM/Fe 3 O 4 -MS to a certain extent. Our results confirmed that microwave mediated hyperthermia could amplify the antitumor efficacy of ADM/Fe 3 O 4 -MS by activating ferroptosis and the introduction of Fe 3 O 4 nanoparticles can significantly improve TACE for HCC. This study confirmed that it was feasible to use uniform-sized gelatin microspheres co-loaded with Fe 3 O 4 nanoparticles and adriamycin to enhance the efficacy of TACE for HCC. Graphical Abstract
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Bioresources and Bioprocessing
·
2022
·Vol. 9
·期 1
·1-15
·
IF 4.983
Cheng Guoqing,Ding Huili,Chen Guanglin,Shi Hongjie,Zhang Xu,Zhu Minglong,Tan Wensong
Sulfate-containing wastewater has a serious threat to the environment and human health. Microbial technology has great potential for the treatment of sulfate-containing wastewater. It was found that nano-photocatalysts could be used as extracellular electron donors to promote the growth and metabolic activity of non-photosynthetic microorganisms. However, nano-photocatalysts could also induce oxidative stress and damage cells. Therefore, the interaction mechanism between photosynthetic nanocatalysts and non-photosynthetic microorganisms is crucial to determine the regulatory strategies for microbial wastewater treatment technologies. In this paper, the mechanism and regulation strategy of cadmium sulfide nanoparticles (CdS NPs) on the growth of sulfate-reducing bacteria and the sulfate reduction process were investigated. The results showed that the sulfate reduction efficiency could be increased by 6.4% through CdS NPs under light conditions. However, the growth of Desulfovibrio desulfuricans C09 was seriously inhibited by 55% due to the oxidative stress induced by CdS NPs on cells. The biomass and sulfate reduction efficiency could be enhanced by 6.8% and 5.9%, respectively, through external addition of humic acid (HA). At the same time, the mechanism of the CdS NPs strengthening the sulfate reduction process by sulfate bacteria was also studied which can provide important theoretical guidance and technical support for the development of microbial technology combined with extracellular electron transfer (EET) for the treatment of sulfate-containing wastewater.
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Natural Product Communications
·
2022
·
IF 1.496
Bozhan Tan,Zhiwen Qi,Guliang Yang,Haiyan Zhong
Tangeretin (Tan) possesses great anti-oxidation and anti-inflammation bioactivities; however, it is accompanied by poor water solubility, which leads to inefficient cellular internalization. To address this issue, a reactive oxygen species (ROS)-triggered poly (thioether-polyesters) micelle (PDHP, PEG-DTT) was designed and prepared via self-assembly, which consisted of poly (thioether-polyesters) as the hydrophilic shell, and the drug Tan as the hydrophobic inner core. The micelles (Tan@ PDHP), with a 63.15% loading efficiency of Tan, showed negligible cytotoxicity, high stability in phosphate-buffered saline buffer (pH = 7.4), and continuous release of Tan with the stimulation of H2O2. In addition, this Tan loading micelle was more efficient in responding to the formation of ROS in the lipopolysaccharide-stimulated RAW264.7 cells compared to that of the free Tan. In short, the strategy of encapsulating the low solubility Tan in ROS-triggered poly (thioether-polyesters) micelles provides an effective assay of enhancing Tan's antioxidative activity.
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LANGMUIR
·
2022
·
IF 4.331
Qiangtao Zhu,Dongyu Pan,Yangyi Sun,Dongming Qi
Hollow structures in TiO2 materials can enhance the photocatalytic properties by reducing the diffusion length and improving the accessibility of active sites for the reactants. However, existing approaches for preparing hollow TiO2 materials have two drawbacks that restrict their engineering applicability: first, a heavy reliance on templates to form a hollow structure, which makes the preparation laborious, complicated, and costly; second, difficult-to-achieve high crystallization while maintaining the small grain size in calcinated TiO2, which is crucial for enhancing photocatalytic activity. Herein, a simple, effective method is proposed that not only enables the preparation of hybrid TiO2–SiO2 hollow spheres without the template fabrication and removal process via microemulsion technology but also achieves both high crystallization and a small grain size in calcinated TiO2 at once through the calcination of amorphous TiO2 with organosilane at a high temperature of 850 °C. The prepared TiO2–SiO2 hollow spheres with tunable sizes demonstrate high photocatalytic activity with a maximum k value of 133.74 × 10–3 min–1, which is superior to commercial photocatalyst P25 (k = 114.97 × 10–3 min–1). In addition, Au can be doped in the hybrid TiO2–SiO2 shell to gain Au-doped hollow spheres that show a high k value of up to 694.14 × 10–3 min–1, which is 6 times larger than that of P25 and much better than that reported in the literature. This study not only provides an effective approach to stabilize and tune the grain growth of the TiO2 photocatalyst during calcination but also enables the simple preparation of hollow TiO2-based materials with controllable hollow nanostructures.
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