Nature Communications
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2026
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IF 18.1
Li Chao,Chen Zehao,Li Wentao,Deng Ronghui,Huang Lingan,Song Yifan,Wang Yiqun,Cui Guoqing,Liu Huawei,Yu Jiakuo
Excessive transforming growth factor-β1 (TGF-β1) signaling is a key driver of the pathological processes of fibrosis and matrix disorganization in tendinopathy, yet current treatments do not directly target this fibrotic microenvironment. Here we show that a self-assembling peptide composed entirely of natural amino acids, AsPep-FTSQ, can locally capture TGF-β1 and remodel the pathological tendon niche. Injecting AsPep-FTSQ into rat and beagle models of tendinopathy resulted in the formation of an interconnected nanofibrous network in situ that selectively sequesters excess TGF-β1. This network suppresses pro-fibrotic signaling, limits pathological tendon cell (TC) state transitions, and promotes collagen realignment. These effects improve tendon structure and functional repair across species. This fully natural, self-assembling peptide composed of amino acids provides a modular strategy for local cytokine sequestration and suggests a therapeutic approach for tendinopathy and potentially other fibrotic soft-tissue disorders.
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JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
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2026
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IF 2.6
Fang Zhien,Chen Changdong,Chen Shengli,Zhu Jiyuan
In order to enhance the corrosion resistance of AZ91D magnesium alloy in chloride media, a superhydrophobic composite coating was developed through a process involving zinc-based phosphating, hydrothermal treatment, and stearic acid modification. Initially, a zinc-based phosphating film was prepared in a phosphating solution comprising Na 3 PO 4 12H 2 O, ZnSO 4 7H 2 O, NaNO 2 , and NaF. Subsequently, micro-nanostructures were grown in an alkaline hydrothermal system composed of ZnSO4 7H2O and sodium citrate. The formation of a low-surface-energy layer was achieved through the process of stearic acid impregnation. SEM, XRD, XPS, and EDS analyses revealed a multilevel rough surface morphology composed of radial petal-like and plate-like structures, primarily consisting of ZnO, Mg(OH) 2 , and zinc/magnesium stearate. Wetting tests demonstrate that the contact angle of the coating firstly increases and subsequently decreases in accordance with rising ZnSO 4 concentrations. At a concentration of 0.04 mol/L, the contact angle reaches 160.6°, with a rolling angle of approximately 7°, thereby achieving a typical superhydrophobic state. Electrochemical impedance spectroscopy indicates that the composite coating enhances charge transfer resistance by approximately seven orders of magnitude compared to the bare AZ91D sample, with low-frequency impedance |Z| reaching 109 Ω cm 2 . Following a 168-h immersion in a 3.5 wt.% NaCl solution, the mass loss of the coated sample was found to be negligible, the solution pH remained essentially unchanged, and the surface Cl content after corrosion was only about 0.1%, a result that significantly outperforms that of the substrate. The system has been demonstrated to provide highly efficient and stable corrosion protection for magnesium alloys through the synergistic action of Mg(OH) 2 sealing and the hydrophobic stearate layer.
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Science China-Technological Sciences
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2026
·Vol. 69
·期 8
·1820501
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IF 5.1
Miao Xiao,Song Shiqi,Yang Yanming,Zhang Peiyu,Ren Guina
In response to the problems encountered in clean water production and environmental restoration, this paper designed a multifunctional interfacial evaporation device. The evaporator was constructed by integrating a carbon quantum dot-bismuth oxybromide (CQD/BiOBr-E) supporting layer with an agaric-hydrogel photothermal conversion layer. Thanks to its excellent non-wetting property (CA = 158.3°), the floating layer can selectively remove oil. Importantly, the degradation of water-soluble pollutants has been achieved. Even after 10 degradation cycles, the degradation efficiency can still reach 92.6%, showing that CQD/BiOBr-E has excellent long-term degradation stability. The active species capture experiment demonstrated that ·O 2 − and h + are the main active species. With the agaric-hydrogel as the photothermal layer, the assembled interfacial evaporator reached an evaporation rate of 1.52 kg m −2 h −1 . This multifunctional interfacial evaporator is designed to provide solutions for environmental pollution and water shortage problems.
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Journal of Food Measurement and Characterization
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2026
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IF 3.6
Yang Fang,Lei Sichao,Ma Renyi,Zhang Wen,Luo Minhui,Xie Chenyang
To develop a novel intelligent packaging material capable of real-time food freshness monitoring and preservation, this study prepared a pH-responsive bioactive film (KCNB) by incorporating blueberry anthocyanins (BA) and nano‑zinc oxide (NanoZnO) into a konjac glucomannan/chitosan (KGM/CS) matrix. The resulting KCNB film was structurally characterized and functionally evaluated and results confirmed the successful dispersion of NanoZnO and BA within the matrix. The film exhibited excellent UV‑blocking capacity, significantly enhanced antioxidant activity (DPPH radical scavenging rate increased to 77.57%), and effective antibacterial efficacy against E. coli and S. aureus , which collectively help prevent light‑induced deterioration, chemical oxidation, and microbial spoilage. Crucially, the film displayed a reversible color transition from red to green across the pH range of 2–12, providing a basis for its function as a visual freshness indicator. When applied to chicken breast preservation, the KCNB film, through the synergistic action of these multiple functions, effectively slowed down spoilage, maintained a lower total volatile basic nitrogen (TVB‑N) level, and thereby extended the shelf life by approximately 4 days compared with the control group. This study demonstrates that the developed multifunctional film holds high potential for application in intelligent bioactive packaging of meat products.
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Nature Communications
·
2026
·
IF 18.1
Jiang Jinhui,Pan Yiwen,Zhao Jingyi,Zhang Siwei,Ma Fulong,Zhang Zicong,Liu Mengli,Qiu Zijie,Zhao Zheng,Sun Jianwei,Kwok Ryan T. K.,Xiong Yu,Lam Jacky W. Y.,Han Wei,Tang Ben Zhong
Organic circularly polarized room-temperature phosphorescence (CPRTP) materials represent an emerging research frontier with broad application prospects. However, achieving efficient and controllable CPRTP remains challenging due to inefficient chirality transfer and the limited ability to regulate chiral environments. Here, we develop a strategy involving self-assembled chiral homopolypeptides to realize manipulable CPRTP. Chiral homopolypeptides functionalized with achiral phosphorescent terminals are first designed, which self-assemble into vesicles exhibiting weak CPRTP. Remarkably, dispersing these vesicles into a poly(vinyl alcohol) matrix induces structural reorganization, leading to inversion and significant amplification of CPRTP. Experimental and computational studies reveal the critical role of matrix-assistance in chirality propagation, inversion, and amplification. Moreover, multicolor afterglow films with tunable emissions are readily achieved by varying the terminal phosphor. This work not only establishes a universal platform for constructing tunable CPRTP materials through homopolypeptide self-assembly but also provides deep mechanistic insights into supramolecular chirality manipulation.
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Journal of Food Measurement and Characterization
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2026
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IF 3.6
Jia Ziyu,Zeng Xintang,Zhayitijiang Zilalan,Ma Bohan,Zou Xianfeng
This research involved preparing soy protein isolate (SPI) and xanthan gum (XG) conjugates (SPI-XG con) through the Maillard reaction (MR). The effects of temperature and time on Maillard reaction products (SPI-XG con) were evaluated, with degree of grafting (DG), intermediate products, browning degree, emulsifying activity index (EAI), and emulsifying stability index (ESI) serving as the key indicators. Results indicated that the optimal MR conditions were 90 °C and 1.5 h. Under these conditions, DG reached a maximum of 24.81%. Compared with SPI, the performance of the optimized conjugate was enhanced by 554.47% and 461.87% in EAI and ESI, respectively. MR could improve the emulsifying property of the conjugate and further enhance emulsion stability. Characterization techniques, including Fourier transform infrared spectroscopy, polyacrylamide gel electrophoresis, and protein secondary structure analysis, also verified the formation of SPI-XG con. Changes in the morphology of SPI following the MR were observed via scanning electron microscopy. Water-in-oil-in-water (W/O/W) emulsions were prepared with an optimized conjugate. The W/O/W emulsions stabilized with conjugate showed smaller droplets size and higher apparent viscosity. The present study explored the possibility of obtaining W/O/W emulsions by using SPI-XG con prepared via MR, and a theoretical application for further study was also made.
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Nature Communications
·
2026
·Vol. 17
·期 1
·1699
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IF 15.7
Sui Huiting,Lou Wenhua,Xiao Shibing,He Jia,Wu Fuling,Liu Ying,Wei Jianbiao,Lu Haijie,Sun Huajun,Ma Xiaoguang,Zhang Shujun
Defect microstructures, particularly dislocations, are pivotal in determining the functional properties of ferroelectric thin films. While their density is routinely considered, the critical role of their spatial configuration has remained largely unexplored and difficult to control. Here, we develop a controlled self-assembly strategy for dislocations in Bi(Fe,Mn)O 3 thin films on Ni-Cr that directly addresses this challenge. By employing a LaNiO 3 buffer layer, we template a discontinuous-columnar grain structure and guide the self-assembly of edge dislocations along grain boundaries in a topologically-protected configuration. The resulting ordered microstructure promotes a more uniform strain field and more coherent FeO 6 octahedral tilting, significantly enhances polarization homogeneity, leading to a lower domain-switching barrier and a more uniform domain pinning effect. Consequently, the BFMO thin film exhibits dramatically superior aging stability after 60 days at 60 °C, exhibiting far smaller reductions in remanent polarization (~20%) and coercive field (~35%) compared to the BFMO thin film grown directly on Ni-Cr. These findings establish a defect engineering paradigm wherein the deliberate dislocation rearrangement is leveraged to unlock superior ferroelectric performance.
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MICROCHIMICA ACTA
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2026
·Vol. 193
·期 3
·145
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IF 5.4
Jia Bao-Zhu,Zhang Wen-Feng,Yin Qing-Chun,Rui Xue-Ying,Luo Lin,Xu Zhen-Lin
A dual-mode immunosensor based on polydopamine@Prussian blue nanoparticles (PDA@PB NPs) was developed for rapid and sensitive detection of benzocaine (BZC) in aquatic food. PDA@PB NPs possess excellent peroxidase-like activity, photothermal conversion efficiency, and antibody-binding capacity, enabling simple, crosslinker-free antibody immobilization. Upon target recognition, the sensor produces a distinct blue color via TMB–H 2 O 2 oxidation and a robust near-infrared photothermal signal, allowing dual-mode quantitative determination. Under optimized conditions, the sensor showed a linear range of 0.01–1000 ng/mL, with detection limits of 0.33 ng/mL (colorimetric) and 0.82 ng/mL (photothermal). The integration of colorimetric and photothermal outputs improves detection accuracy, reduces matrix interference, and eliminates the need for complex instrumentation. Validation with spiked real samples confirmed its reliability and applicability. This portable, cost-effective immunosensor offers a promising tool for on-site monitoring of BZC residues in aquatic products, contributing to enhanced food safety surveillance. Graphical abstract
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EUROPEAN JOURNAL OF NUTRITION
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2026
·Vol. 65
·期 2
·52
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IF 4.5
Liu Kaiyue,Li Na,Fan Jiayi,He Siliang,Tang Weixiang,Cao Yaxin,Shen Liang,Sun Shuyang,Du Chengcheng,Du Chao
Purpose This study investigated the basic composition, in vitro digestibility, biological activities, and potential bioactive peptides of Pacific oyster (PO), Mytilus edulis (ME), Argopecten irradians (AIS), and Meretrix meretri x L. (MML) after simulated gastrointestinal digestion (SGD). Methods SGD products were prepared using the INFOGEST 2.0 model, and their nutritional properties and biological activities were analyzed. A comprehensive peptidomic profiling of the digested samples was conducted using nano-liquid chromatography-tandem mass spectrometry (nano-LC MS/MS) analysis. Results All four shellfish exhibited a nutritional profile characterized by high protein and low-fat content. The digestibility of shellfish increased progressively, while the average molecular weight (MW) of the hydrolysates gradually decreased during SGD, with the intestinal hydrolysates showing the highest overall digestibility. Biological activity analysis demonstrated that intestinal digestion products from all four species exhibited notable ABTS radical scavenging activity and α-glucosidase inhibition activity, with PO and ME exhibiting the strongest effects. A total of 349, 99, 314 and 105peptides were identified from the digestion products of PO, ME, AIS, and MML, respectively. Among these, PO and AIS showed the highest sequence similarity, sharing 69 identical peptides. By contrast, MML displayed distinct peptidomic characteristics, including a higher proportion of large MW peptides. Conclusion This study provides a comprehensive peptide catalog of shellfish digestion products and offers new insights into the biological activities of shellfish-derived peptides, supporting their potential as functional food resources.
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Nature Communications
·
2026
·
IF 15.7
Hongyu Cao,Fengnian Zhuang,Yanfei Wang,Tang Sheng,Wenyuan Liu,Zhiwen Bai,Mengdie Lan,Zhaoqi Li,Wenshan Yu,Shengping Shen
The challenge of dendrite growth limiting metal battery lifespan, despite extensive chemical composition optimizations for artificial solid electrolyte interphases (ASEIs), necessitates the development of ASEI design routes. Regulating the ASEI crystallographic microstructure offers a promising yet underexplored solution with efficacy uncertainty. Critical issue lies in what is the optimal crystallographic microstructure state. Using the ZnS ASEI in aqueous Zn batteries as a case study, here we report the effects of grain orientation and grain boundary density on the performance of Zn negative electrode. The results reveal the existence of an optimal microstructure state—predominant in-plane (111) orientation coupled with a critical grain boundary density of ~55 μm/μm 2 —which delivers an 18-fold lifespan extension, and over 3400 cycles with a Coulombic efficiency of 99.92% at 5 mA cm -2 , surpassing the efficacy of most chemical composition manipulations. Mechanistically, the (111) orientation integrates higher electrochemical kinetics and mechanical strength. As grain boundary density increases to tens of μm/μm 2 , the enhancement in electrochemical kinetics coincides with compromised mechanical strength, with their trade-off delineating the critical density that maximizes electrode cycling stability. Our findings exemplify an efficient ASEI design route—crystallographic microstructure engineering. Dendrite growth compromises the cycling life of metal batteries. Here, authors propose a crystallographic microstructure engineering approach to the artificial solid electrolyte interphase, demonstrating a high efficacy in stabilizing the zinc metal electrode during plating/stripping.
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Nature Communications
·
2026
·
IF 18.1
Yin Chenxu,Sun Zhecheng,Tang Kunlin,Zou Weixin,Wan Haiqin,Liu Zhao-Qing,Dong Lin
Photocatalytic reduction of CO 2 to natural gas using water vapor is a promising strategy for carbon recycling and renewable energy storage. However, the selectivity of current catalysts still remains a big challenge. Herein, we construct IrCu alloys on TiO 2 nanosheets to promote photocatalytic CO 2 to methane with 98.6% selectivity and 7.9% quantum efficiency at 365 nm under non-sacrificial ambient conditions. The performance is competitive with most other reported metal-based photocatalysts. Experimental and theoretical calculations demonstrate that the intensive H 2 O adsorption on Ir/TiO 2 hinders *H transfer, inevitably generating the H 2 by-product. Conversely, hydrophobic Cu effectively optimizes the interfacial hydrogen-bond network on IrCu/TiO 2 , predominantly in H-down configurations for H 2 O adsorption on the asymmetric charge-polarized Cu δ+ -Ir δ- structure, which facilitates the kinetic migration of dissociated *H to *CO-Cu sites, resulting in the reduced energy barrier for the key *CHO intermediate. This finding enables high CH 4 selectivity on IrCu/TiO 2 , deepening our understanding of gas-solid interfacial water vapor in the enhanced natural gas synthesis.
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INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
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2026
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IF 3.7
Zhang Zhihui,Deng Jianxin,Lu Yang,Tang Xujie
In this study, electrojet micro-printing was used to deposit a checkerboard-textured (CF x ) n /CaF₂/C-ZrO₂/TiO₂ soft-hard composite coating onto the rake face of the YT15 tool. The microstructure of the coating was characterised, and the influence of graphite content in the lubricating phase on cutting performance during dry machining of 304 stainless steel was explored. The results indicate that the incorporation of textured hard phases and graphite significantly improved cutting performance. Among the samples, the CBM2 coating, with higher carbon content, showed the lowest cutting forces and friction coefficients at cutting speeds of 50–150 m/min. In contrast, the CBM1 coating, with lower carbon content, exhibited the least tool wear and best performance at 200 m/min, due to the embrittlement of excess graphite at high temperatures.
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