Journal of Materials Chemistry C
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2024
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IF 5.7
Jiahao Pan,Yuchen Zhang,Zhentao Pang,Yu Deng,Zhenda Lu
This work presents a high-content platform for investigating the critical interplay between the nanoparticle cluster size, structure, and plasmon-enhanced fluorescence at a single particle level. The platform enables the controlled assembly of pre-synthesized, bio-conjugatable Ag@Au nanocubes into clusters with varying sizes and configurations, ultimately arranged in an array pattern. Notably, the platform statistically reveals that Ag@Au nanocubes achieve over two orders of magnitude greater fluorescence enhancement compared to Au nanoparticles alone. Moreover, it identifies a crucial size regime for maximizing fluorescence enhancement. Clusters containing 1–4 nanocubes exhibit a direct correlation between the fluorescence intensity and the number of particles, as well as cluster configuration. Compact clusters display a significantly stronger fluorescence response compared to loosely packed configurations. This high-content platform offers a powerful approach for the rapid, simultaneous characterization of multiple nanoparticles, paving the way for efficient, large-scale fluorescence-based detection.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2025
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IF 5.4
Xuan Li,Yuyan Cao,Yihui Shen,Yulin Wu,Shicong Cui,Lingli Cheng,Xuechun Yang,Zheng Jiao
Nowadays, designing sensing materials possessing both high sensitivity and humidity resistance is still a challenge in the field of sensing materials. In this work, a ternary Ag nanoparticles decorated NiCo 2 O 4 /NiO (Ag/NiCo 2 O 4 /NiO) composite with hollow nanocage structure has been successfully obtained, which uses ZIF-67 as a template combined with self-etching method, followed by NaBH 4 reduction of silver ions. For the synergistic effect of the novel morphology, the presence of Ag nanoparticles and hydroxyl absorbent NiO, and the formation of p-p heterojunction between NiCo 2 O 4 and NiO, Ag/NiCo 2 O 4 /NiO exhibits good humidity resistance and high-sensitive to n-butanol. The mesoporous hollow nanocage morphology not only provides abundant adsorption sites for target gases, but also facilitates the diffusion of water molecules. The doping of Ag nanoparticles can regulate the adsorption of oxygen on the surface of gas sensing materials, improving the sensitivity while suppressing the hydroxyl poisoning reaction process. The hydroxyl absorbent NiO in Ag/NiCo 2 O 4 /NiO can both directly absorb water and form p-p heterojunction structure with NiCo 2 O 4 , which improves sensor performance while suppressing hydroxyl poisoning. In the gas sensing tests, the optimal Ag/NiCo 2 O 4 /NiO composites can achieve a high response value of 31.41, as well as rapid response/recovery times (65 s/47 s) to 100 ppm n-butanol at the working temperature of 170 °C. Moreover, it displays a wide detection range (1–120 ppm), a low detection limit (0.27 ppm), excellent selectivity to n-butanol, and superior long term stability (maintaining a response value of 84.68 % after 14 days). Notably, the optimal Ag/NiCo 2 O 4 /NiO demonstrates great humidity-tolerant ability with a response values fluctuation of 16 % under the range of 33 %-80 % relative humidity. This research provides a feasible approach for designing practical gas sensing materials with high sensitivity and moisture resistance.
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NEW JOURNAL OF CHEMISTRY
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2025
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IF 2.5
Xiao-Jian Li,Xinli Lu,Yunxia Wang,Zhanquan Zhang,Yongfa Zhang
This study successfully developed a highly sensitive electrochemiluminescence (ECL) sensor based on the ECL resonance energy transfer mechanism for detecting the key biomarker of acute myocardial infarction, heart–type fatty acid binding protein (h–FABP). Through the meticulous design of the Ag/Cu2O/Ti3C2 ternary nanocomposite material, this material demonstrated significant catalase–like catalytic activity, enabling the efficient decomposition of H2O2 to generate more superoxide radicals (O₂•⁻), thereby significantly enhancing the ECL signal of the luminol–H2O2 system. Notably, AgS quantum dots (AgS QDs), due to broad–spectrum ultraviolet absorption overlapping with the ECL emission spectrum of luminol, triggered an efficient energy resonance transfer effect, resulting in the decrease of ECL intensity. NH2–MIL–101(Fe) was utilized to couple with AgS QDs (AgS QDs@NH2–MIL–101(Fe)), which can further enhance the quenching efficiency. Based on this signal–off strategy, an ultrasensitive detection platform for h–FABP was successfully constructed. Experimental results indicated that the immunosensor exhibited an excellent response relationship within a wide linear range from 1.00 fg mL–1 to 100 ng mL–1, and a low detection limit reached 0.36 fg mL–1 (S/N = 3). This study provides an innovative methodological approach for ultra–trace detection of myocardial injury markers and demonstrates significant application potential in early clinical diagnosis.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
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IF 8.5
Xinru Wang,Jie Zhang,Jinyu Shan,Dong Yang,Guangming Tian,Yunzhi Dang,Jianhua Ma
This study focuses on bacterial cellulose (BC), a material with a three-dimensional network structure, excellent biocompatibility, and superior mechanical properties, to address its inherent limitations of insufficient antibacterial activity and poor rehydration capability. Silver nanoparticles (AgNPs) were synthesized in situ on the BC surface via a hydrothermal method, followed by immersion in polyethylene glycol (PEG) and cefoperazone sodium (CEFNa) solutions to prepare BC/Ag/PEG/CEFNa composite films. The BC films and composites were comprehensively characterized using techniques such as XRD, SEM, and FTIR spectroscopy. Systematic characterization results revealed that the introduction of PEG not only increased the film's moisture absorption and water vapor permeability by 2.8 and 1.7 times, respectively, but also enhanced the CEFNa loading capacity to 1.6 times that of pure BC. Antibacterial experiments demonstrated that while pure BC films exhibited no antibacterial activity, the composite films showed inhibition zone diameters of 15.5 mm, 17.5 mm, and 12.3 mm against Escherichia coli , Staphylococcus aureus , and Pseudomonas aeruginosa , respectively. Mouse wound healing experiments indicated that the wound healing rate of the composite film treatment group was significantly improved by 21.9 % compared to the pure BC group after 15 days. These results demonstrate that the prepared BC/Ag/PEG/CEFNa composite films possess excellent physicochemical properties, significant antibacterial activity, and remarkable wound-healing effects, highlighting their great potential as advanced wound dressings for skin injury repair.
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FOOD CHEMISTRY
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2025
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IF 9.8
Zhaoyuan He,Chengxiang Fu,Shuling Meng,Jiaqi Luo,Jieke Qiu,Jianing Huang,Xiaoge Duan,Jiakang He,Jinzi Wang,Hailan Chen
Despite global regulatory bans due to its hematotoxic effects, chloramphenicol (CAP) persists as an illicit veterinary antibiotic in food animals owing to its low cost and broad-spectrum efficacy. Current analytical methods to monitor CAP residues in animal-derived foods face critical limitations: instrumental analyses rely on expensive equipment and specialized operations, while immunoassays lack sufficient sensitivity for regulatory compliance. Here, we develop an ultrasensitive electrochemical aptasensor leveraging a zirconium MOF‑silver nanocomposite (Zr-MOF@Ag), which effectively enhances charge transfer and facilitates aptamer immobilization. Under optimized detection conditions, the electrochemical aptasensor yielded a wide linear range of 1–100 ng/mL (r 2 = 0.990) with an ultralow limit of detection (LOD) of 9.94 pg/mL. Additionally, the sensor showed no cross-reactivity with other veterinary drugs, with RSD of 1.00–0.94 % for intra- and inter-batch repeatability, respectively. The recovery rates of spiked samples ranged from 95.1 to 108.4 %.
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SENSORS AND ACTUATORS B-CHEMICAL
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2025
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IF 7.7
Yan Zeng,Yijun Lin,Jiawei Chen,Yan Sun,Peng Qi,Peng Wang
Early detection and diagnosis are essential for effectively preventing and treating complex pathogenic bacterial infections. This study presents an innovative approach for on-site, ultrasensitive pathogen detection by integrating a uniquely designed probe binding mode with novel nanomaterial structures within a lateral flow immunoassay (LFIA) platform. Through a galvanic replacement reaction, gold is non-uniformly deposited onto a silver core, resulting in the formation of Ag@pore-Au structures. The abundant nanopores and porous surface of these structures create a high density of "hot spots", significantly enhancing their surface-enhanced Raman scattering (SERS) performance. We systematically characterized the SERS and detection capabilities of the synthesized Ag@pore-Au Raman-dye micron particles (MPs) probe. The results conclusively demonstrated that this structural probe exhibits a robust SERS signal, paving the way for its successful application in LFIA. By integrating the Ag@pore-Au Raman-dye MPs probe into the LFIA platform, we achieved rapid, quantitative detection of Escherichia coli and Staphylococcus aureus. This enhanced platform overcomes the limitations of traditional LFIA, notably its high detection limit of 10 CFU/mL and its inability to provide quantitative results. Furthermore, a dual-channel detection mode enabled the simultaneous and specific identification of both bacterial strains. The platform's efficacy was validated through successful detection in real sample matrices. This research offers novel insights and methodologies for pathogen detection in the medical field, providing an effective solution for on-site pathogen diagnosis and real-time environmental monitoring.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2025
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IF 3.8
Song Xinyi,He Zhaoyuan,Tan Siyuan,Cong Siyu,Lu Wuli,Mai Zedeng,Jiang Mingsheng,Wen Yu,Liu Cheng,Chen Hailan
Deoxynivalenol (DON), a highly stable and globally prevalent mycotoxin, has become a critical food safety concern due to its widespread contamination in animal feed, particularly in corn, wheat, and other cereal-based ingredients. As one of the most frequently detected mycotoxins in feedstuffs, DON contamination not only causes significant economic losses in livestock production but also poses severe health risks to animals, including vomiting, immunosuppression, and growth retardation, which may ultimately affect human health through the food chain. Existing detection methods for DON are often limited by time-consuming procedures or analytical complexity. Here, we report a novel surface-enhanced Raman scattering-based lateral flow immunoassay (SERS-LFIA) for rapid, sensitive, and specific detection of DON residues in animal feeds. The biosensor employs core-shell Au@4-MBA@Ag nanoparticles functionalized with 4-mercaptobenzoic acid (4-MBA) as a Raman reporter and DON-specific antibodies for target recognition. After systematic optimization, the SERS-LFIA platform achieved both qualitative and quantitative detection within 16 min, with an exceptionally low limit of detection (LOD) of 0.01 µg/kg. The assay demonstrated excellent specificity, showing no cross-reactivity with other major mycotoxins, including aflatoxin B 1 , zearalenone, and ochratoxin A. Remarkable reproducibility was evidenced by intra- and inter-batch coefficients of variation (CV) of 3.51% and 2.19%, respectively. The test strips maintained stability for at least 3 months at 4 ± 0.5 °C and for 2 months at 25 ± 0.5 °C, making them particularly suitable for routine monitoring in feed mills and farms. This innovative SERS-LFIA system represents a significant advancement in mycotoxin detection technology, offering a robust, field-deployable solution for monitoring DON contamination in animal feed, which is crucial for ensuring feed safety and animal health. Graphical
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JOURNAL OF ALLOYS AND COMPOUNDS
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2025
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IF 6.3
Jinzhou Bai,Yanbai Shen,Sikai Zhao,Ang Li,Wenxin Wang,Wenbao Liu,Wengang Liu
Formamide (CH 3 NO) presents significant health hazards due to its prolonged volatilization like formaldehyde, making rapid and accurate detection critical. However, studies on formamide sensors remain limited. Hence, a high-performance formamide sensor was achieved using Ag quantum dots (QDs) modified SnS 2 nanosheets, operating efficiently at room temperature of 25 °C. The microstructure and material properties of the nanocomposites were fully characterized, showing that ∼4.5 nm of Ag QDs were uniformly dispersed on the SnS 2 nanosheets with a thickness of ∼14 nm. The optimal Ag QDs-SnS 2 nanocomposites sensor demonstrated remarkable improvement over pure SnS 2 , including a high response of 13.3–100 ppm formamide, along with good selectivity, repeatability, and long-term stability. Density functional theory (DFT) was utilized to reveal the catalyst effect of Ag QDs at the atomic level and adsorption behaviors of CH 3 NO molecule on sensing material. The enhanced sensing mechanism was attributed to the extraordinary catalyst activities of Ag QDs, and modulation of electronic structures of nanocomposites, as well as the spillover effect. This work provides a novel insight into the formamide sensing mechanism, paving the way for the future design of high-performance formamide sensors.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2025
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IF 5.4
Yunfei Shen,Huaiqi Shi,Keying Qu,Zuopeng Li,Bolong Yang,Zhansheng Wu
Multifunctional cotton fabric holds significant promise for domestic and healthcare applications. A key challenge remains developing sustainable fabrication routes for mechanically durable cotton textiles integrating intrinsic and photothermally amplified antibacterial functions. Herein, we prepared ZIF-8/67-loaded Ag nanoparticles on cotton fabric using in-situ reduction technology (ZIF-8/67-Ag@CCT). Subsequent dip-coating with polydimethylsiloxane (PDMS) produced ZIF-8/67-Ag@CCT@PDMS, enhancing superhydrophobicity. The modified fabric exhibited exceptional superhydrophobicity (water contact angle: 148.55 ± 0.21°) and UV-blocking capabilities (UPF value: 186). The surface demonstrated excellent self-cleaning properties against dyes and maintained robust stability after 30 washing cycles and immersion in acidic/alkaline solutions (>97.0% antibacterial efficacy retention). Critically, the fabric exhibited excellent biocompatibility, as validated by human induced pluripotent stem cell-derived skin organoid assays showing no adverse effects on cell proliferation, apoptosis, or survival rates. Antibacterial effects originated from the penetration of AgNPs and Ag⁺/Zn²⁺/Co²⁺ ions into bacterial structures, disrupting metabolism via reactive oxygen species (ROS) generation. The multifunctional ZIF-8/67-Ag@CCT@PDMS fabric presents a highly promising solution for durable antibacterial medical textiles, offering combined antibacterial activity, exceptional stability, self-cleaning, UV resistance, and biocompatibility.
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MICROCHEMICAL JOURNAL
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2025
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IF 5.1
Linlin Chen,Qunlong Wang,Yuting Jing,Ruijing Wang,Xuefeng Wang
Excessive food pigments can be harmful to human health and in severe cases can cause cancer. Unlike conventional and time-consuming detection techniques, surface enhanced Raman scattering (SERS) is a fast, sensitive and accurate method. Ag NPs@NiO foam is developed as an efficient SERS substrate, featuring a large specific surface area and suitable charge transfer pathways. R6G can be detected at a concentration as low as 10 −14 M with an analytical enhancement factor (AEF) as high as 1.682 × 10 12 , demonstrating the high sensitivity of Ag NPs@NiO foam. In practical applications, Ag NPs@NiO foam is successfully used for the detection of food blue, amaranth, allura red in beverages, with the limit of detection lower than the safety limits in China. This facile and highly sensitive substrate provides a solid foundation for fast and accurate food analysis.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2025
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IF 4.6
Rui Zhou,Miao Dong,Yiwei Wu
N, Si, S co-doped graphene quantum dots (N, Si, S-GQDs) were synthesized from waste toner and glutathione (GSH) via a one-pot hydrothermal method. Combined with o-phenylenediamine (OPD), a rapid, visual, and autocatalytic ratiometric fluorescence sensor of N, Si, S-GQDs/OPD was fabricated for detecting Ag(I) and Fe(III) ions by producing 2,3-diaminophenazine (oxOPD) under pH 8, which emits yellow fluorescence at 560 nm while quenching the blue fluorescence of N, Si, S-GQDs at 440 nm due to an inner filter effect. With the increase of Ag(I)/Fe(III), the blue fluorescence of N, Si, S-GQDs at 440 nm was gradually weakened, along with the enhancement of yellow fluorescence at 560 nm. Hence, this color change from blue to yellow under UV light enables semi-quantitative visual detection. The sensor demonstrates high sensitivity with detection limits of 0.016 µg mL −1 for Ag(I) and 0.010 µg mL −1 for Fe(III), and it successfully detects these ions in lake and tap water without pretreatment. The autocatalytic mechanism involves Ag(I) and Fe(III) reduction to Ag nanoparticles and Fe(II), respectively, which further catalyze the reaction, enhancing selectivity and efficiency. The method is cost-effective, simple, and suitable for on-site environmental monitoring.
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Molecular Catalysis
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2025
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IF 4.9
Jiayi Zhou,Hongyao Zhao,Yifang Zhang,Hongyang Zhu,Yueji Cai,Yanyun Wang,Danhong Shang,Tongyi Yang,Fu Yang,Jingjing Tang
The solar-driven photothermal photocatalytic contaminant degradation and water evaporation coupled technique is promising for practical wastewater treatment. This study developed photothermal HNTs@Ag/C-5 nanocomposites by polycondensation of tannic acid with silver and following carbonization to construct plasmonic silver nanoparticle onto halloysite nanotubes (HNTs). The incorporation of Ag onto HNTs enhanced electron-hole separation, enabling efficient activation of potassium peroxymonosulfate (PMS) under sunlight. A floatable integrated device was constructed by anchoring the catalyst to a melamine sponge via calcium ion-cross-linked sodium alginate. This device achieved 84.3 % degradation of carbamazepine (CBZ) in 90 min under light, with a reaction rate constant of 0.01685 min − ¹, nearly four times higher than unmodified halloysite nanotubes. The photocatalytic PMS activation over HNTs@Ag/C-5 also show great potential for detoxifying other pharmaceutical compounds such as tetracycline (TC) and norfloxacin (NFX) in wastewater. Radical trapping and quenching experiments confirmed hydroxyl radicals (·OH) as the dominant reactive oxidative species in CBZ degradation. Additionally, the device functioned as a solar-driven photothermal evaporator, achieving an evaporation rate of 1.654 kg m − ² h − ¹. Reusability tests demonstrated consistent performance, with only a 4 % efficiency drop after multiple degradation cycles. This reported monolith evaporator affords possible opportunity for treating complex wastewater when harnessing the evaporation to obtain freshwater and synchronously degrade contaminant.
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