Biomaterials Science
·
2022
·Vol. 10
·期 7
·1812-1820
·
IF 7.59
Yanping Xu,Dinghu Zhang,Jie Lin,Xiaoxia Wu,Xiawei Xu,Ozioma Udochukwu Akakuru,Hao Zhang,Zhewei Zhang,Yujiao Xie,Aiguo Wu,Guoliang Shao
Circulating tumor cells (CTCs) usually shed from primary and metastatic tumors serve as an important tumor marker, and easily cause fatal distant metastasis in cancer patients. Accurately and effectively detecting CTCs in a peripheral blood sample is of great significance in early tumor diagnosis, efficacy evaluation, and postoperative condition monitoring. In this work, a TiO2@Ag nanostructure is structured as a SERS substrate, rhodamine 6G (R6G) is used as a Raman signal molecule, the reduced bovine serum protein (rBSA) acts as a protective agent, and folic acid (FA) acts as a target molecule to specifically recognize cancer cells. A TiO2@Ag-based SERS bioprobe is successfully prepared with the feature of ultrahigh sensitivity, good specificity, low toxicity, and high accuracy in CTC detection. The remarkable SERS activity of the TiO2@Ag nanostructure is synergistically contributed by surface plasmon resonance and photon-induced charge transfer mechanism. The limit of detection for rhodamine 6G (R6G) molecules adsorbed on the TiO2@Ag SERS substrate is 5 × 10−14 M, and the corresponding SERS enhancement factor can reach 7.61 × 107. The designed TiO2@Ag–R6G–rBSA–FA SERS bioprobe is effectively utilized in detecting various cancer cells in rabbit blood, and the limit of detection (LOD) for the target cancer cell is 1 cell per mL. Notably, CTCs in peripheral blood of six clinical liver cancer patients are successfully recognized via the TiO2@Ag-based SERS bioprobe. Accurately recognizing CTCs in peripheral blood based on the TiO2@Ag–R6G–rBSA–FA SERS bioprobe is also carefully verified by in situ immunofluorescence staining experiments, which directly supports the CTC detection accuracy of the SERS strategy. These results demonstrate that the TiO2@Ag-based SERS bioprobe has great application potential in early screening and diagnosis of tumors.
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JOURNAL OF HAZARDOUS MATERIALS
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2020
·
IF 9.038
Fei Miao,Yanfeng Liu,Mingming Gao,Xin Yu,Pengwei Xiao,Mei Wang,Shuguang Wang,Xinhua Wang
Nowadays, microplastic pollution has been brought into focus for its hazards to aquatic life. However, researches on the electrocatalytic treatment for efficient degradation of microplastics are still insufficient. Herein, an electro-Fenton like (EF-like) technology based on TiO 2 /graphite (TiO 2 /C) cathode was put forward to degrade polyvinyl chloride (PVC), a typical microplastic in water. It exhibited a remarkable performance on PVC degradation via cathodic reduction dechlorination and hydroxyl radical (O H) oxidation simultaneously. Besides, the effects of reaction temperature and initial PVC concentration were investigated. Under optimal conditions, the dechlorination efficiency of PVC reached 75 % after potentiostatic electrolysis at -0.7 V vs. Ag/AgCl for 6 h. The intermediate products were explored during the degradation of PVC microplastics. The surface morphologies and molecular weight of PVC changed accordingly. Based on these results, a possible degradation process for PVC was proposed. This work demonstrated that such a heterogeneous EF-like technology using TiO 2 /C cathode was hopefully to provide an eco-friendly method for microplastic wastewater treatment.
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PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
·
2015
·Vol. 14
·期 6
·1197-1206
·
IF 2.267
Li Zhi,Ou-Yang Ya,Liu Yang,Wang Yi-Qiu,Zhu Xia-Li,Zhang Zhen-Zhong
Recently, porous carbons have showed great potential in many areas. In this study, TiO 2 -doped mesoporous carbonaceous (TiO 2 @C) nanoparticles were obtained by a simple one-pot hydrothermal treatment, folic acid (FA) was conjugated to TiO 2 @C through an amide bond, then Mitoxantrone HCl (MTX) was adsorbed onto TiO 2 @C-FA and a drug delivery system, TiO 2 @C-FA/MTX was obtained. TiO 2 @C-FA/MTX showed a much faster MTX release at pH 4.5 than at pH 6.0 and pH 7.4. Furthermore, compared with free MTX, this drug delivery system showed a dose-dependent cytotoxicity by varying the irradiance, and afforded higher antitumor efficacy in cultured PC3 cells in vitro . The ability of TiO 2 @C-FA/MTX to combine chemotherapy with photodynamic activity enhanced the cancer cell killing effect in vitro , demonstrating that TiO 2 @C-FA/MTX has a great potential for cancer therapy in the future.
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NANOTECHNOLOGY
·
2023
·
IF 3.5
Feitong Lu,Wei Wei,Qiang Shi,Ning Wang,Yi Xiao,Zibo Li
TiO2/graphene oxide (GO) nanocomposites with high contact interface were prepared with glycol 400 (PEG400) served as dispersant. This nanocomposite exhibits improved photocatalytic efficiency in contrast with the nanocomposite prepared without PEG400. In this work, the photocatalytic performance was investigated by observing the degradation rate of Rhodamine B (RhB). And it is found that the mass ratios of GO in nanocomposites plays an important role. When the mass ratio of GO reached 45%, the photocatalytic performance of the nanocomposites reached the highest, which is ~72%. Moreover, the photocatalytic mechanism was studied through theoretical calculations, which can be summarized as follows: 1. The presence of GO decreases the band gap of TiO2 nanoparticles. 2. GO inhibits the the recombination of photogenerated electron-hole pair. 3. GO improves the adsorption capacity of TiO2 nanoparticles for RhB. This work promoted the application of TiO2/GO nanocomposites in wastewater treatment.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2020
·
IF 7.489
Xiaoyao Shen,Xiaoying Sun,Jing Liu,Jianzhong Hang,Lujiang Jin,Liyi Shi
Stable dispersion of TiO 2 particle is very desirable for its practical applications in various fields. It is a big challenge to stabilize pigment TiO 2 with relatively large size (200–300 nm) in low viscosity (~10 cP) systems. In the current work, we introduced a general strategy using a hydrophobic-hydrophilic structure to achieve single-dispersed TiO 2 particles with long storage stability in low viscosity systems. The modified TiO 2 particles (~250 nm) can be re-dispersed into water/glycol ethers mixture to form single dispersed suspension without any additives. Our study shows that the dispersion can be stable at least 60 days at room temperature and the rheological property is similar to the Newtonian fluids showing an extremely low yield stress at relatively high solid concentration. This work is expected to introduce a new strategy to improve the dispersion stability of the large size nanoparticles in low viscosity systems.
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CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Ziqiang Gong,Na Yang,Zhenxing Chen,Bin Jiang,Yongli Sun,Xiaodong Yang,Luhong Zhang
With the purpose of avoiding the limitation of oil/water density relationship, as well as achieving the continuous separation, two types of filtering materials with inverse wettability have attracted extensive attention. In our work, a superhydrophilic mesh was fabricated via a series of procedures, including the deposition of TiO 2 seed layer on the surface, the growth of TiO 2 nanowires by a hydrothermal method and calcination process. As expected, the as-prepared superhydrophilic mesh turned to be superhydrophobic after the decoration by low surface energy reagent. The formation mechanism of grass-like TiO 2 nanowires was proposed and surface morphological optimization conditions were studied. As for the oil/water application, the T-shaped bidirectional device combining the meshes with inverse wettability was adopted for achieving continuous oil/water separation. Meanwhile, the separation test showed that the separation efficiency of greater than 99% and high flux were obtained for various oil/water mixtures. Furthermore, according to the results simulating the realistic industrial application, the as-prepared meshes exhibited excellent reuse durability and stability in corrosive environment. The extension of TiO 2 nanowires on mesh, cooperating the multiple wettability behaviors could be regarded as a prospective candidate for large-scale oil/water separation.
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ELECTROCHIMICA ACTA
·
2014
·
IF 4.086
Wenzhang Li,Guanhua Jin,Haishi Hu,Jie Li,Yanghui Yang,Qiyuan Chen
Dye-sensitized solar cells (DSSCs) based on phosphotungstic acid–TiO 2 composites (PT) and WO 3 nanoparticle incorporated TiO 2 photoanodes were successfully constructed by doctor blading TiO 2 paste containing PT and various amounts of WO 3 . Film features were investigated by scanning electron microscopy, X-ray photoelectron spectroscopy, X-ray diffraction, transmission electron microscopy, and ultraviolet–visible spectroscopy. Photoelectrochemical properties were examined by the photocurrent–voltage ( J – V ) curves as well as monochromatic incident photon-to-photocurrent conversion efficiency and electrochemical impedance spectroscopy (EIS) measurements. Compared with the DSSC based on pure P25 films, that based on PT/P25 films yielded a 16.9% higher J sc and a 21.3% higher η , while that based on PT/P25 + 1/70WO 3 films resulted in a 49.2% higher J sc and a 40.3% higher η . EIS data demonstrated that charge transfer resistance was clearly reduced by introducing PT and WO 3 into TiO 2 films. The introduction of PT and WO 3 was observed to promote electron transfer and retard recombination synergistically, leading to a significant improvement in cell performance.
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CARBON
·
2018
·
IF 7.082
Changchao Jia,Xiao Zhang,Katarzyna Matras-Postolek,Baibiao Huang,Ping Yang
Z-scheme reduced graphene oxide (rGO)/TiO 2 -bronze (TiO 2 -B)/W 18 O 49 photocatalyst consisted of rGO, super-thin TiO 2 -B nanosheets , and W 18 O 49 nanofibers was fabricated by a two-step solvothermal synthesis route. The TiO 2 -B nanosheets were tightly attached on rGO firstly. W 18 O 49 nanowires were then grown on rGO/TiO 2 -B. Precursors and reaction conditions play important roles for getting the optimal microstructure. The ternary photocatalyst is able to absorb sunlight ranging from ultraviolet to near infrared regions , which makes full use of light for efficiently photocatalytic degrading organic pollutants. The light absorption intensity and photon-generated carrier transfer efficiency are both improved with adding rGO. The localized surface plasmon resonance effect arose from the nonstoichiometric W 18 O 49 is in favour of the absorption range of the rGO/TiO 2 -B/W 18 O 49 composite broadening to near infrared light range. The photocatalytic mechanism of Z-scheme rGO/TiO 2 -B/W 18 O 49 composite was verified by an electron spin resonance test. The conduction band of TiO 2 -B and the valence band of W 18 O 49 are used in the photocatalytic degradation of rhodamine B, facilitating the efficient separation of photogenerated carriers . The rGO/TiO 2 -B/W 18 O 49 heterostructure exhibits an excellent photocatalytic performance under full solar-spectrum irradiation. The result may represent a new strategy for the construction of nanocomposites with suitable band structure in the efficient application of full solar light.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Yifang Mi,Na Wang,Xingyu Fang,Jia Cao,Meng Tao,Zhihai Cao
Integration photocatalysis with membrane technology offers a potential solution to combat fouling dilemma. Herein, an interfacial polymerization polyamide nanofiltration (NF) membrane with self-cleaning ability was prepared by incorporation of carbon quantum dots /titanium dioxide (CQD/TiO 2 ) nanoparticles (NPs). The addition of hydrophilic CQD/TiO 2 NPs promoted membrane hydrophilicity and endowed the NF membrane with high water flux (67.22 L m −2 h −1 ), which was 1.8 times compared with that of the pristine membrane, and salt rejection of Na 2 SO 4 (96.7%). Simultaneously, the prepared NF membranes maintained high dye rejection to methyl blue (MYB, 99.1%) and congo red (99.8%). Moreover, visible light-driven photocatalytic ability of CQD/TiO 2 allowed the membranes to efficiently degrade MYB dyes absorbed on the membrane surface. In stark contrast to the results of cyclic physical water cleaning, the flux recovery ratios were maintained 97–98% without sacrificing MYB rejections during the cyclic fouling-irradiation process, demonstrating stable and efficient self-cleaning performance. Even after continuous membrane fouling for 72 h, the water flux only decreased by 6.7% after visible light irradiation, surpassing the performance of pristine polyamide NF membrane (decreased by 23.4%). The hydrophilicity and visible light-driven self-cleaning ability make the prepared NF membrane via interfacial polymerization highly suitable for efficient dye wastewater treatment.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2018
·Vol. 25
·期 31
·31250-31261
·
IF 2.8
Wang Liang,Xie Yingjuan,Liu Wenxiu,Wang Qi,Cao Wenbin
TiO 2 microstructures were synthesized via a facile one-step route for enhanced intrinsic photocatalytic performance. The prepared TiO 2 microstructures are featured by both mesoporous core-shell structures and coexposed {001}/{101} facets. Their intrinsic photocatalytic performance were remarkably enhanced due to their high specific surface area, coexposed {001}/{101} facets, and promoted separation of photogenerated carriers. Furthermore, the origin and detailed mechanism for diethylenetriamine (DETA) that served as a high efficient stabilizer of TiO 2 {001} facet have been theoretically investigated. Finally, a new DETA-modified Ostwald ripening mechanism was originally proposed when studying the growth mechanism of the mesoporous core-shell TiO 2 spherical microstructures with coexposed {001}/{101} facets.
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ACS Applied Materials & Interfaces
·
2020
·
IF 8.758
Enzhu Lin,Ni Qin,Jiang Wu,Baowei Yuan,Zihan Kang,Dinghua Bao
Powder-form piezocatalysts suffer from poor recyclability and pose a potential threat of creating serious secondary pollution, which restrict their practical applications. Thin-film piezocatalysts, which not only exhibit good recyclability but also fully contact with solution, are believed to be one of the solutions to address these problems. In this work, the nanostructured BaTiO3 (BTO) thin films were fabricated by a facile hydrothermal method for their potential applications in piezocatalysis. The vertically standing BTO nanosheets grown on the top of TiO2 nanorod arrays exhibited superior piezocatalytic performance as well as piezo-electrochemical property. Given the different strain states between thin-film piezocatalyst and powder-form piezocatalyst, both the impact force of water and isostatic pressure are taken into consideration in finite element method (FEM) simulation. The FEM simulation shows that a stronger piezoelectric filed can be built in BTO nanosheets because of their easier deformation, and thus can lead to a higher piezocatalytic degradation efficiency. Our work presented here is expected to provide a potential route for the nanoengineering of thin-film piezocatalysts and clarify the catalytic mechanism for substrate-fixed piezocatalysts.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2022
·
IF 7.139
Suqing Peng,Weilin Zhong,Hailun Zhao,Chao Wang,Zhipeng Tian,Riyang Shu,Ying Chen
Photocatalytic hydrogen production and thermal storage are effective ways to convert solar energy into storable chemical energy and thermal energy , but they only respond to specific spectrum. In order to improve the energy conversion and storage efficiency of solar energy in the solar spectrum, hydrothermal and photo-deposition method were employed to synthesized photothermal catalyst while and Au/TiO 2 @PCM composite microcapsules were fabricated by electrostatic adsorption self-assembly methods. Micro-morphologies and structures were detailed characterized by SEM , XRD , UV-Vis, etc. As calculated from the DSC results for effective, enthalpy value , the loading rates of Au/TiO 2 shell for the microcapsule were 12.6% and 15.4% corresponding to rod-shaped and sheet-shaped samples. To test their catalytic performance, the samples were dispersed in the same concentration of glycerol solution, and showed that the light to hydrogen efficiencies were 11.4‰ and 5.0‰ for ATR@PCM and ATF@PCM, respectively with the increasement of 53.8% and 56.1% comparing to their corresponding catalyst nanoparticle suspensions. Photo-thermal conversion efficiencies of ATR@PCM and ATF@PCM were 62.74% and 53.32% after 60 min-irradiations, and they were 48.22% and 25.96% higher than that of Me-PCM. Therefore, it was confirmed that the composite phase change microcapsules prepared in this study have the dual functions of energy storage and photothermal catalysis. Higher solar light to hydrogen energy conversion efficiency may be attained in future study if the stored thermal energy can be successfully employed to activate organic components for helping catalytic hydrogen generation .
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