RSC Advances
·
2015
·Vol. 5
·期 103
·84410-84422
·
IF 3.84
Hai-Min Shen,Gong-Yuan Zhu,Wu-Bin Yu,Hong-Ke Wu,Hong-Bing Ji,Hong-Xin Shi,Yi-Fan Zheng,Yuan-Bin She
Renewable β-cyclodextrin (β-CD) was immobilized onto the surface of hybrid silica using ethylenediamine as linking groups to construct an adsorbent in water treatment (CD@Si), and the obtained CD@Si was characterized through FT-IR, XPS, EDX, contact angle measurement, TGA, solid-state 13C NMR, SEM, and XRD analyses. The effect of initial pH, contact time on the adsorption performance of CD@Si for p-nitrophenol, and the adsorption kinetics, adsorption isotherms, adsorption thermodynamics, reusability and adsorption mechanism were investigated systematically, which indicate that the adsorption of p-nitrophenol onto CD@Si is a very fast process. The adsorption equilibrium can be reached in 15 s with an acceptable equilibrium adsorption capacity of 69.6 mg g−1 at pH 7.0, which is much faster than many reported adsorbents based on β-CD. The adsorption of p-nitrophenol onto CD@Si follows the pseudo-second-order model, obeys the Freundlich model, and is a feasible, spontaneous, and exothermic process which is more favorable at lower temperatures. And the formation of an inclusion complex and a hydrogen bond interaction are two origins of p-nitrophenol being adsorbed onto CD@Si. Additionally, CD@Si can be recycled and reused for at least five runs with an acceptable adsorption capacity, and is a very promising adsorbent for the fast adsorption of p-nitrophenol or its analogues from the aqueous phase. Additionally, this work also provides a strategy to increase the adsorption rate of adsorbents based on β-CD.
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MICROCHEMICAL JOURNAL
·
2017
·
IF 3.034
Agustín G. Crevillén,Mercedes de Frutos,José Carlos Diez-Masa
Isotachophoresis (ITP) coupled to zone electrophoresis (ZE), either free zone electrophoresis (FZE) or gel electrophoresis (GE), carried out mainly in capillaries and, although less frequently, also in microchips, is a powerful preconcentration and separation technique which has been successfully used for the study of many low molecular-weight analytes. However, this analytical technique has been scarcely applied for proteins separation. In this work, an on-chip transient ITP coupled to free zone electrophoresis (t-ITP-MFZE) mode with LIF detection is developed for the preconcentration and separation of the proteins α-lactalbumin and β-lactoglobulin. Firstly, for LIF detection, the proteins were off-chip fluorescently labeled with the fluorogenic reagent Chromeo P503. Then, several separation parameters in t-ITP-MFZE mode such as leading electrolyte, terminating electrolyte, separation voltage, and injection time were optimized to achieve the maximum sensitivity while maintaining an adequate resolution between α-lactalbumin and β-lactoglobulin in a single column configuration t-ITP. Using the optimized electrolytes (50 mM imidazole/HCl pH = 8 as leading electrolyte and 100 mM imidazole/12 mM HEPES pH = 8 as terminating electrolyte) separation of both proteins was achieved in less than 4 min with peak resolution of 1.5. The LODs were 55 nM and 380 nM, for α-lactalbumin and β-lactoglobulin, respectively, which are adequate for some food allergenicity studies. Finally, comparison of the optimized t-ITP-MFZE method to the equivalent MFZE method, carried out also in microchips but without the isotachophoretic preconcentration step, provided preconcentration indexes for both proteins around 10.
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CHINESE JOURNAL OF POLYMER SCIENCE
·
2019
·Vol. 37
·期 7
·664-673
·
IF 2.804
Liu Ya-Di,Zhang Qiang,Yu Xin-Hong,Liu Jian-Gang,Han Yan-Chun
For poly(9,9-dioctylfuorene) (PFO), β phase (coplanar conformation with the intra-chain torsion angle of 165°) has a greater conjugation length and higher degree of order compared to those of α phase, which favors charge carrier transport. However, the highest content of β phase obtained so far is 45%. We propose to increase the content of β phase by promoting the solution aggregation of PFO molecules and extending film-forming time. For this purpose, 1,8-diiodooctane (DIO) is added to PFO o -xylene solution, which enhances the interaction of PFO chains and improves the planarity of PFO backbone, resulting in the formation of ordered aggregation. The aggregates act as nucleation centers to promote the formation of β phase. The content of β phase increases with increasing DIO concentration and reaches a platform of 39% as DIO is more than 4 vol%. Furthermore, the film is kept in a sealed environment with o -xylene atmosphere for 3 h, thus the PFO molecules have enough time to diffuse to the crystallization front and achieve disorder-order transition. As a result, the crystallinity of PFO is improved significantly and the content of β phase increases to 52%, reaching the highest value reported so far.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2020
·
IF 5.162
Zhong Shi,Zhuangzhuang Shi,Mengmeng Wu,Yaqi Shen,Guoqiang Li,Ting Ma
Food-grade emulsion gels have attracted increasing attention in food and drug manufacturing, owing to their potential as novel delivery systems for lipophilic bioactive ingredients. Emulsion gels are structurally either a polymeric gel matrix with incorporated emulsion droplets (emulsion-filled gels), or a network of aggregated emulsion droplets (emulsion particulate gels). In this study, a novel emulsion gel was prepared by formulating an oil-in-water (O/W) emulsion stabilized by sanxan alone, followed by heating and cooling treatment, resulting in a structured solid system. Stable O/W type sanxan emulsion gels (SEGs) were obtained at sanxan concentration >0.5% ( w /w). Fluorescence microscopy results confirmed the adsorption of sanxan on oil droplet surfaces. The effect of temperature and sanxan/oil concentrations on the rheological and textural properties of the SEGs was evaluated: the SEG containing 1% (w/w) sanxan and 20% (w/w) sunflower oil exhibited excellent rheological and textural properties. Further, the addition of 10 mM Na + or 5 mM Ca 2+ greatly enhanced the thermostability of the SEG. The potential of SEGs as sustained-release delivery systems for β-carotene was also explored. The findings are of great interest for the development of novel delivery systems based on emulsion gels stabilized by sanxan for the sustained release of lipophilic components.
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ANALYTICA CHIMICA ACTA
·
2024
·
IF 5.7
Hui Zhou,Jihang Zhai,Huiyuan Gong,Ru Fang,Yongmei Zhao,Wen Luo
Background The formation of amyloid-β (Aβ) plaques is one of the key neuropathological hallmarks of Alzheimer's disease (AD). Near-infrared (NIR) probes show great potential for imaging of Aβ plaques in vivo and in vitro. Dicyanoisophorone (DCIP) based Aβ probes have attracted considerable attention due to their exceptional properties. However, DCIP probes still has some drawbacks, such as short emission wavelength (<650 nm) and low fluorescence intensity after binding to Aβ. It is clear that further modification is needed to improve their luminescence efficiency and sensitivity. Results We designed and synthesize four novel pyrrolidine-alkylamino-substituted DCIP derivatives ( 6a - d ) as imaging agents for β-amyloid (Aβ) aggregates. Compound 6c responds better to Aβ aggregates than the other three compounds ( 6a , 6b and 6d ) and its precursor DCIP. The calculated detection limit is to be as low as 0.23 μM. Compound 6c shows no cytotoxicity in the tested concentration for SH-SY5Y and HL-7702 cells. Additionally, compound 6c is successfully applied to monitor Aβ aggregates in live SH-SY5Y cells and APP/PS1 transgenic mice . The retention time in the transgenic mice brain is much longer than that of age-matched wild-type mice. Significance The results indicates that compound 6c had an excellent ability to penetrate the blood-brain barrier and it could effectively distinguish APP/PS1 transgenic mice and wide-type mice. This represents its promising applications for Aβ detection in basic and biomedical research .
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FOOD HYDROCOLLOIDS
·
2023
·
IF 10.7
Jinpeng Li,Liang Li
A novel nanoparticle was prepared with soy protein isolate (SPI)-oat β-glucan (OG) conjugates obtained by extrusion (extruded SPI-OG) to stabilize the emulsion. Extruded SPI-OG nanoparticles exhibited a spherical and stable structure. The 90 °C and 110 °C extruded SPI-OG nanoparticles had higher absolute value of zeta potential (13.35 mV and 12.24 mV, respectively) and an average particle size of less than 200 nm. Moreover, interfacial tension of nanoparticles increased with increasing extrusion temperature, but diffusion rate and surface hydrophobicity were decreased, while penetration rate ( K p ) and rearrangement rate ( K r ) increased and then decreased. The 90 °C and 110 °C extruded SPI-OG nanoparticles had the highest K p and K r , and increased by 38.14% and 40.11%, 175.16% and 168.15%, respectively, compared with K p and K r of SPI nanoparticles. And emulsion stabilized by these two nanoparticles exhibited the extraordinary emulsion stability of 81.64% and 80.07%, respectively (p > 0.05). These results demonstrated that adsorption rate of extruded SPI-OG nanoparticles to the oil-water interface decreased, but could rapid unfold and rearrange at the interface to form interfacial layer for stabilizing emulsion. And adsorption capacity and microstructure of emulsion also proved that more extruded SPI-OG nanoparticles could adsorb onto the interface to form a dense interfacial layer. This may provide a theoretical basis for novel nanoparticles as interfacial stabilizer in emulsion.
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RSC Advances
·
2014
·Vol. 4
·期 69
·36675-36681
·
IF 3.708
Jiangang Gao,Shaobo Yu,Benpei Zheng,Qingping Song,Xingxing Peng,Ying Lin,Gang Zou,Qijin Zhang
A triblock PEG-based polymer (CP1113) with a clear ABA structure was synthesized from 1,13-tridecanedioic acid (DA13) and mono-methoxy-poly(ethylene glycol) (MePEG) via condensation reaction. An inclusion complex (IC1113) with β-cyclodextrin (CD) was prepared by co-precipitation and the IC formation was confirmed by transmittance determination with a UV-Vis spectrometer. Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), and thermogravimetry analysis (TGA) were adopted to characterize IC1113 and the experimental data showed that a channel-type polypseudorotaxane was formed. For further investigating the inclusion behaviors, 1H-NMR spectroscopy was used to determine the molar ratio between CP1113 and β-CD and 2D ROSEY spectra were recorded to elucidate the IC formation mechanism. The results revealed that β-CD threaded onto the polymer main chain at a molar ratio of 7.8 : 1 and the molar ratio of EG segments to β-CD in IC1113 was ca. 8.28 : 1. It was concluded that β-CD accommodated both the methylene and the PEG segments and herein hydrophobic and hydrogen-bonds interactions played the most important roles with a hydrophobic stabilizing and hydrogen-bond inducing effect, which “amplified” the hydrophobic interaction between β-CD and the methylene segment along the hydrophilic PEG segments.
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BIOORGANIC CHEMISTRY
·
2020
·
IF 4.831
Ibrahim Khalifa,Du Xia,Kunal Dutta,Jinmeng Peng,Yangyang Jia,Chunmei Li
Advanced glycation end-products (AGEs), which instigate many disorders, are mostly mediated by dicarbonyl rearrangements. We studied the corresponding mechanisms of the anti-glycation effects of two anthocyanins purified from mulberry fruits, namely cyanidin 3-glucoside (C3G) and cyanidin 3-rutinoside (C3R), on glycated β-lactoglobulins (β-Lg). Both mulberry anthocyanins (MAs) inhibited the AGEs-formation in a dose-dependent manner, but the effect of C3R was significantly stronger than that of C3G (p < 0.05). MAs inhibited AGEs-formation by selectively trapping dicarbonyls, especially glyoxal. The UPLC-ESI-Q-TOF-MS results characterized that C3R formed mono- and di-glyoxal adducts, where C3G only created di-glyoxal adducts. Additionally, C3R could directly interact with some of the glycation sites of β-Lg. Overall, GO-trapping and β-Lg-MAs covalent/noncovalent binding are disclosed as the key mechanisms of the anti-AGEs activity of MAs on β-Lg, which could be valorised as effectual AGEs inhibitors in proteins-rich matrices.
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高影响因子
INORGANIC CHEMISTRY
·
2018
·
IF 4.7
Rajaboopathi Mani,Huaidong Jiang,Santosh Kumar Gupta,Ziqing Li,Xiulan Duan
The europium ion probes the symmetry disorder in the crystal structure, although the distortion due to charge compensation in the case of aliovalent dopant remains interesting, especially preparation involves low and high temperatures. This work studies the preparation of the β-Ca2SiO4 (from here on C2S) particle from Pechini (C2SP) and hydrothermal (C2SH) methods, and its luminescence variance upon doping with Eu2+ and Eu3+ ions. The blue shift of the charge-transfer band (CTB) in the excitation spectra indicates a larger Eu3+–O2– distance in Eu3+ doped C2SH. The changes in vibrational frequencies due to stretching and bending vibrations in the FTIR and the Raman spectra and binding energy shift in the XPS analysis confirmed the distorted SiO44– tetrahedra in C2SH. The high hydrothermal temperature and pressure produce distortion, which leads to symmetry lowering although doping of aliovalent ion may slightly change the position of the Ca atoms. The increasing asymmetry ratio value from C2SP to C2SH clearly indicates that the europium ion stabilized in a more distorted geometry. It is also supported by Judd–Ofelt analysis. The concentration quenching and site-occupancy of Eu3+ ions in two nonequivalent sites of C2S were discussed. The charge state and concentration of europium ions in C2SP and C2SH were determined using X-ray photoelectron spectroscopy measurements. The C2S particles were studied by X-ray powder diffraction, FTIR, Raman, BET surface area, TGA/DTA, electron microscopy, XPS, and luminescence spectroscopy. The impact of citrate ion on the morphology and particle size of C2SH has been hypothesized on the basis of the microscopy images. This study provides insights that are needed for further understanding the structure of C2S and thereby improves the applications in optical and biomedical areas and cement hydration.
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Polymer Chemistry
·
2021
·Vol. 12
·期 42
·6123-6133
·
IF 5.582
Yue Liu,Zhiping Su,Shuangcheng Jiang,Haoran Sun,Haixia Lyu,Zenghong Xie
In this study, a new bridged bis(β-cyclodextrin) (CD) functionalized urea–formaldehyde monolithic column was prepared by “one-pot” method within 30 minutes. The structures of bridged-CD and the obtained monolithic column were characterized by scanning electron microscopy, nuclear magnetic resonance spectroscopy, infrared spectroscopy and energy dispersive spectroscopy. The chromatographic performance of native-CD-monolith, N,N′-methylenebisacrylamide (MBA)-bridged-CD-monolith and N,N′-(1,2-dihydroxyethylene) bisacrylamide (DAA)-bridged-CD-monolith was systematically evaluated by separating five analytes. As a result, all tested analytes were separated on an MBA-bridged-CD-monolith and DAA-bridged-CD-monolith with high resolutions (1.21–6.80), which showed that the bridged-CD-monolith exhibited a better chromatographic performance with enantioselectivity due to providing mixed-modes such as hydrophilicity, hydrogen bonding, ionic dipole and synergy compared with those of the native-CD-monolith. In addition, the enantioselectivity of the bridged-CD-monolith was related to the polarity of a functional linker. As a new chiral separation material, the bridged-CD functionalized urea–formaldehyde monolithic column may be widely applied in the analysis of chiral compounds due to its rapid preparation and higher enantioseparation performance.
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Food Biophysics
·
2022
·Vol. 17
·期 4
·598-611
·
IF 3.34
Yang Pan-pan,Shi Yu-gang,Li Dong-hui,Chen Ru-kang,Zheng Mei-zhi,Ma Kai-zhi,Xu Nuo,Dong Li-juan,Li Teng
To guarantee the safety and quality of food and prolong its shelf life, a novel multi-functionalized chitosan-based film with the outstanding antimicrobial property was prepared by incorporating with β -cyclodextrin ( β CD) and octyl gallate (OG). The OG encapsulation with β CD to form inclusion complexes ( β CD/OG-IC) endows OG with improved water-solubility and physicochemical stability. The formation of β CD/OG-IC has been proved through analytical techniques including FTIR, XRD, DSC and 1 H NMR. Then the chitosan (CS) films containing β CD/OG-IC were fabricated and their mechanical, physical properties and antimicrobial activities against four foodborne pathogens ( E. coli , S. aureus , L. monocytogenes and P. fluorescens ) were evaluated. The increased antibacterial activities of the CS film containing β CD/OG-IC were demonstrated by measuring the diameter of the inhibition zone. Meanwhile, the composite films showed higher tensile strength, more excellent water vapor resistance in contrast to pure CS films. Additionally, the composite films showed slow-release capacity and enhanced antibacterial efficacy to remarkably extend the shelf life of blueberry and asparagus. Our results substantially suggest that CS film containing β CD/OG-IC is a potential candidate for use as a multi-functionalized layer in the food-packaging system.
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2020
·
IF 3.99
Jing Guo,Jianguo Jiang,Xiaolong Gu,Xia Li,Tianqing Liu
Multiple emulsions provide a facile route for particle preparation due to their ability to be used as liquid templates. Herein, biocompatible oil-in-water-in-oil (O 1 /W/O 2 ) double emulsions were fabricated using a two-step procedure and applied as templates for preparation of calcium alginate hydrogels with encapsulated β-carotene. The encapsulation efficiency ( EE ) of β-carotene showed a positive correlation to the outer-to-inner droplet size ratio of the O 1 /W/O 2 emulsion. The maximum EE , ∼50 wt%, could be achieved in the freshly prepared O 1 /W/O 2 emulsion when using aqueous alginate of 2 wt% as the intermediate phase and β-carotene-loaded R-(+)-limonene of 0.1 wt% as the inner oil phase. Gelation of the alginate phase was induced by addition of a small amount of aqueous CaCl 2 into the β-carotene-loaded O 1 /W/O 2 emulsion. The resulting hydrogels in water were characterized by laser diffraction and several microscopy measurements. The hydrogels showed good spherical shape and their average size was a little larger than that of the emulsion droplet templates. This work contributed to the understanding of encapsulation in O 1 /W/O 2 emulsion system and provided a novel methodology for encapsulation of carotenoids and other lipophilic bioactives.
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危险品化学品经营许可证（带存储）