INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2024
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IF 8.1
Yuanchen Zhu,Gang Liu,Zhenying Cui,Hongwei Yang,Fang Liu,Baolei Jiang,Lei Chen
Blending hydrogen into existing natural gas pipelines is a cost-effective method for large-scale hydrogen transportation. However, high hydrogen ratios cause hydrogen embrittlement in pipeline steel, limiting transportation efficiency. Due to complex structures and harsh application conditions, existing coatings are difficult to apply on pipelines. To tackle such issues, we propose an ionic liquid-polymer composite coating using epoxy resin as coating substrate, based on the competitive adsorption of methane and hydrogen on pipeline steel. Ionic liquids with high methane selectivity were selected via quantum chemical calculation. The protective effect of coatings was characterized using hydrogen pre-charging constant strain tensile tests. Simulation and experimental results demonstrate that epoxy resin coatings reduce hydrogen embrittlement in X80 steel. Modified with selective CH 4 /H 2 permeability ionic liquids, the epoxy resin coating enhances methane and hydrogen competitive adsorption on the steel surface, improving hydrogen embrittlement resistance. This novel coating offers a viable solution for achieving safe and high ratio hydrogen blended transportation in natural gas pipeline.
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COLLOIDS AND SURFACES B-BIOINTERFACES
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2024
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IF 5.4
Juan Wang,Xinchen Zhao,Liyan Qiu
Multidrug resistance (MDR) is an incidental trouble post-chemotherapy, necessitating innovative therapeutic strategies. This study explores the potential of chloroquine (CQ) as a sensitizer for mitoxantrone hydrochloride (MitH) in drug-resistant tumors and introduces a novel pH-responsive drug-induced self-assembly nanovesicle (DIV) based on an amphiphilic polyphosphonitrile (PPAP) for the co-delivery of MitH and CQ. PPAP cannot self-assemble into nanovesicles alone, but when a certain amount of MitH was added, the multiple non-covalent interactions between PPAP and MitH contributed to the formation of DIV, which exactly improved the co-loading content of MitH and CQ to a large extent. CQ prevents MitH efflux and autophagy to reverse MitH resistance. Given the synergy between MitH and CQ at a 1:2 mass ratio with a combination index of 0.40 in K562/ADR cells, MitH and CQ co-loaded DIV (MC-DIV) is constructed and demonstrates a sensitivity index of 7.1 on cytotoxicity compared to free MitH. Furthermore, MC-DIV achieves extended circulation time, synchronous dual-drug delivery, and improved tumor targeting following systemic administration, resulting in exceptional antitumor efficacy in K562/ADR xenograft models with a tumor inhibition rate of 83.0 %. Overall, MC-DIV provides a viable method to maximize the loading capacity of nanocarriers, and potentially serves as a promising formulation for various MitH-resistant tumors.
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Food Chemistry-X
·
2025
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IF 8.2
Jian Ouyang,Ronggang Jiang,Huimin An,Xingchang Ou,Jing Wang,He Xie,Wenjie Fu,Jing Zhang,Hongyu Chen,Qi Liu,Juan Li,Haitao Wen,Ligui Xiong,Jian-an Huang,Zhonghua Liu
Rucheng Baimaocha ( Camellia pubescens ) black tea (RCBT) exhibits floral and sweet attributes with a unique minty-like aroma, distinguishing it from traditional and other innovative black teas. However, its key odorants remain unknown. In this study, gas chromatography-olfactometry (GC-O) combined with aroma extraction dilution analysis detected 26 aroma-active compounds (ACCs), of which 20 ACCs were quantified as odorants of RCBT infusion. In addition, aroma recombination models well simulated the overall aroma characteristics of RCBT infusion, which proved the accuracy of identification and quantification. Omission experiments showed that 12 key odorants played crucial roles in aroma formation of RCBT. Among these, four odorants (methyl salicylate, ( E , Z )-2,6-nonadienal, methyl geranate, and ( E )-2-nonenal), were of great importances for unique minty-like aroma, with significantly higher concentrations compared to other black tea varieties. This study offered a foundational theoretical framework for the processing and quality control of RCBT.
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Scientific Reports
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2017
·Vol. 7
·期 1
·1-9
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IF 4.259
Yi Xin,Wu Yuxuan,Tan Guoxin,Yu Peng,Zhou Lei,Zhou Zhengnan,Chen Junqi,Wang Zhengao,Pang Jinshan,Ning Chengyun
Traced dopamine (DA) detection is critical for the early diagnosis and prevention of some diseases such as Parkinson’s, Alzheimer and schizophrenia. In this research, a novel self-supporting three dimensional (3D) bicontinuous nanoporous electrochemical biosensor was developed for the detection of dopamine by Differential Pulse Voltammetry (DPV). This biosensor was fabricated by electrodepositing palladium nanoparticles (Pd) onto self-supporting nanoporous gold (NPG) wire. Because of the synergistic effects of the excellent catalytic activity of Pd and novel structure of NPG wire, the palladium nanoparticles decorated NPG (Pd/NPG) biosensor possess tremendous superiority in the detection of DA. The Pd/NPG wire biosensor exhibited high sensitivity of 1.19 μA μΜ −1 , broad detection range of 1–220 μM and low detection limit up to 1 μM. Besides, the proposed dopamine biosensor possessed good stability, reproducibility, reusability and selectivity. The response currents of detection in the fetal bovine serum were also close to the standard solutions. Therefore the Pd/NPG wire biosensor is promising to been used in clinic.
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NEW JOURNAL OF CHEMISTRY
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2024
·Vol. 48
·期 36
·15839-15845
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IF 2.7
Tao Wang,Mengyao Shi,Changyan Guo,Jide Wang
ZIF-67 has garnered much attention in the field of photocatalytic water splitting due to the advantages of MOFs and zeolite sieves. However, post-modification and composite strategies have emerged as effective approaches to enhance its photocatalytic performance, particularly in enabling bi-functionality for oxidation-coupled reduction reactions. In this study, 2-mercaptobenzimidazole (MBI) modified ZIF-67 and cadmium sulfide (CdS) composites were prepared to investigate their application in photocatalytic oxidation-coupled hydrogen evolution reactions. The results demonstrated an enhancement in hydrogen production performance over CdS@ZIF-67-MBI, with an increase from 2.39 mmol g−1 h−1 to 4.49 mmol g−1 h−1 upon the introduction of MBI. Moreover, the conversion efficiency of benzyl alcohol reached an improved value of 58.5%. The study findings revealed that the heterogeneous coupling between ZIF-67 and CdS, along with the effective charge transfer facilitated by the anion S, played a decisive role in promoting charge–hole separation of composite materials and improving carrier transport efficiency. This demonstrates the viability of utilizing ZIF-67 in a bifunctional photocatalytic reaction system, thereby paving the way for broader applications of ZIF-67.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2024
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IF 3.8
Da Sheng,Qing He,Zhong-Hua Cao,Lun-Bo Chen,Song-Hai Wu,Yong Liu,Hai-Tao Ren,Xu Han
Although photooxidation of benzyl alcohol to benzaldehyde in aqueous solution is an important chemical process, its selectivity cannot be readily controlled due to the overoxidation of benzaldehyde. In this study, a series of Bi–Mo/CN photocatalysts are synthesized, and their reactivity in photooxidation of benzyl alcohol under visible light is compared. Bi–Mo/CN-2 exhibits high photocatalytic reactivity in the conversion of benzyl alcohol (51%) with a high selectivity toward benzaldehyde of 99.9%. In this process, the formed ≡Bi–OO• and ≡Bi–OOH selectively oxidize benzyl alcohol to benzaldehyde via the H-abstraction pathway after O2 is photoreduced on Bi–Mo/CN, accompanied by the formation of H2O2. Meanwhile, the doped Mo utilizes the produced H2O2 or ≡Bi–OOH to produce ≡Mo–O2 peroxo, which not only contributes to the selective oxidation of benzyl alcohol to benzaldehyde but also effectively prevents overoxidation of benzaldehyde. This work provides new insight into designing novel photocatalysts for selective oxidation of organic substrates.
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CHEMICAL ENGINEERING SCIENCE
·
2024
·
IF 4.1
Yan Ouyang,Qi Liu,Tong Luo,Qinlan Luo,Min Xiao,Hongxia Gao,Zhiwu Liang
CO 2 loaded amine polymerizes during solvent regeneration at temperatures above 100 °C, resulting in the deterioration of solvent performance. Herein, five primary amines were heated to 120, 135 and 150 °C with CO 2 loading of 0.4C/N to study thermal degradation. It was found that 2-amine-1-butanol showed the greatest amine loss of 38.5 % after heating to 135 °C for 672 hrs while 2-amino-2-methyl-1-propanol was most stable with amine loss of 17.4 % under the same conditions. The degradation products were identified and the reaction pathway was studied through density functional theory (DFT) calculation. Furthermore, the transition state for ring closure and opening reactions was analyzed. The ring closure reaction to form oxazolidinones had a higher energy barrier, showing that it was the limiting step. This is further supported by the good agreement with experimental results. The structure–activity relationship showed the strong steric hindrance effect and the methyl group at β-carbon improved the amine stability.
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Energy & Environmental Science
·
2024
·
IF 32.4
Wenhua Xue,Jian Ye,Zhi Zhu,Reeti Kumar,Jun Zhao
The photocatalytic conversion of biomass into valuable chemicals offers a more energy-efficient and low-carbon alternative to traditional thermal catalysis, representing a promising strategy for fine chemical production without relying on fossil fuels. While most studies have focused on catalyst design to improve efficiency, the precise tuning of solvents has been neglected. This study examines the conversion of 5-hydroxymethylfurfural (HMF) into 2,5-diformylfuran (DFF) as a representative biomass alcohol oxidation reaction, revealing a novel strategy for enhancing photocatalytic efficiency through solvent fine-tuning. The introduction of minute quantities of water into an acetonitrile solvent matrix during the HMF oxidation reaction was observed to engender pronounced enhancements in catalytic performance, with the degree of effect contingent on precise water concentration. Trace water is an active participant in the catalytic cycle, diminishing the activation energy barrier for bond cleavage and averting catalyst deactivation. This mechanism also proved applicable to other photocatalysts and various alcohol substrates, highlighting the potential of this strategy for enhancing photoenergy utilization and reaction efficiency.
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2024
·Vol. 40
·期 4
·704-711
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IF 3.1
Zheng Mingdan,Chen Ya,Liu Zhan,Lyu Jiamin,Ye Bo,Sun Ming-Hui,Chen Li-Hua,Su Bao-Lian
Hollow zeolite microspheres have recently attracted much attention for their applications in catalysis, microreactors and biomedicine. Herein, we present hierarchically structured zeolite ZSM-5 microspheres with unique, abundant macropores that allow more efficient use for catalysis. The hierarchically macroporous zeolite ZSM-5 microspheres are synthesized under the assistance of water/oil emulsions and using polystyrene nanospheres as templates. The zeolite microsphere is assembled by uniform hollow zeolite nanospheres. Their large inner cavities and thin zeolite shells lead to smaller diffusion channel and higher improved accessibility to active sites, contributing to high catalytic performance in the catalytic conversion of benzyl alcohol in mesitylene. Such novel zeolite microspheres with impressive performance will be applied to numerous other industrial catalytic reactions.
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ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Yingxue Jin,Jiajing Chen,Wen Xie,Jinni Zhang,Jingjing Yan,Canrong Chen,Jiashi Lin,Zongwei Cai,Zian Lin
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) holds great promise for the rapid and sensitive detection of biomolecules, but its precise detection of small molecule metabolites is hindered by severe background interference from the organic matrix in the low molecular weight range. To address this issue, nanomaterials have commonly been utilized as substrates in LDI-MS. Among them, covalent organic frameworks (COFs), known for their unique optical absorption and structural properties, have garnered significant attention. Despite these advantages, their low ionization efficiency remains a challenge. Herein, a composite material of COF-S@Au nanoparticles (NPs), by incorporating Au NPs into a sulfur-functionalized COF (COF-S) through postsynthetic modification, was designed and adopted as substrates. This hybrid material leverages the synergistic effects of COF-S and Au NPs to improve the desorption/ionization efficiency and minimize background interference. The COF-S@Au NPs demonstrated a 5–16-fold improvement in MS signals of small biomolecules along with a clean background and excellent resistance to salt and protein interference. Their corresponding limits of detection (LODs) were achieved at ∼pmol. Furthermore, the COF-S@Au NPs were applied to analyze metabolites in a triclosan (TCS)-exposed mouse model, successfully identifying 10 differential metabolites associated with TCS toxicity. This work provides a foundation for developing advanced LDI-MS materials for high-performance metabolic analysis and offers valuable insights into TCS metabolic toxicity with potential applications in environmental toxicology.
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JOURNAL OF HAZARDOUS MATERIALS
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2024
·
IF 12.2
Xin Liu,Tiehu Li,Yuhui Liu,Yiting Sun,Yanying Han,Tung Chun Lee,Amir Zada,Zeqi Yuan,Fei Ye,Jiahe Chen,Alei Dang
Sensitive and rapid identification of volatile organic compounds (VOCs) at ppm level with complex composition is vital in various fields ranging from respiratory diagnosis to environmental safety. Herein, we demonstrate a SERS gas sensor with size-selective and multiplexed identification capabilities for VOCs by executing the pre-enrichment strategy. In particular, the macro-mesoporous structure of graphene aerogel and micropores of metal-organic frameworks (MOFs) significantly improved the enrichment capacity (1.68 mmol/g for toluene) of various VOCs near the plasmonic hotspots. On the other hand, molecular MOFs-based filters with different pore sizes could be realized by adjusting the ligands to exclude undesired interfering molecules in various detection environments. Combining these merits, graphene/AuNPs@ZIF-8 aerogel gas sensor exhibited outstanding label-free sensitivity (up to 0.1 ppm toluene) and high stability (RSD=14.8%, after 45 days storage at room temperature for 10 cycles) and allowed simultaneous identification of multiple VOCs in a single SERS measurement with high accuracy (error < 7.2%). We visualize that this work will tackle the dilemma between sensitivity and detection efficiency of gas sensors and will inspire the design of next-generation SERS technology for selective and multiplexed detection of VOCs.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-7
·
IF 15.7
Yao Aiping,Xu Hongliang,Shao Kuizhan,Sun Chunyi,Qin Chao,Wang Xinlong,Su Zhongmin
Soft porous crystals, recognized as the third generation of smart porous materials, can undergo structural deformations in response to external stimuli, such as temperature, pressure, and guest molecules. Currently, the dynamic phase transformations of soft porous crystals are predominantly determined through quantitative modeling based on gas adsorption and powder X-ray diffraction. Herein, we investigate the single-crystal-to-single-crystal structural transformation of covalent organic soft porous crystal modeled on COF-300 and identified nine distinct conformational isomers induced by different guest molecules at room and high temperatures. Notably, COF-300 can maintain its single-crystal structure even at 280 °C and efficiently absorbs polycyclic aromatic hydrocarbons in their molten state. The kinetics of structural transformations among conformational isomers are investigated by combining PXRD and theoretical calculations. The structural transformation from a high-energy state to a low-energy state is a rapid, energetically favorable process, while the reverse transformation is a slow process driven by concentration gradients.
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