NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 45
·19868-19879
·
IF 3.288
Sleshi Fentie Tadesse,Dong-Hau Kuo,Worku Lakew Kebede,Lalisa Wakjira Duresa
Discharging of organic pollutants from industrial activities into the water bodies is a common worldwide problem, which can adversely affect human life and the environment. Recently, many efficient, eco-friendly, and cost-effective photocatalytic methods have been investigated for environmental remediation. In this study, a simple and facile precipitation method at low temperature was proposed for the synthesis of V-doped Mo(O,S)2 oxysulfide. The crystallinity, morphology, elemental composition, and optical and electrical properties of the as-synthesized materials were characterized by XRD, Raman spectroscopy, FT-IR spectroscopy, FE-SEM, TEM, XPS, PL, and EIS. The photocatalytic performance of both bare and V-doped Mo(O,S)2 was evaluated in the degradation of methylene blue (MB) dye. The holes (h+) and hydroxyl radicals (OH˙) were identified as the main oxidative species for MB degradation. V-Mo(O,S)2-10 synthesized with 10% vanadium precursor showed the highest photocatalytic efficiency for MB degradation under visible light irradiation with an apparent rate constant of 0.028 min−1, which was much greater than that of bare Mo(O,S)2 at 0.0098 min−1. Besides, V-Mo(O,S)2-10 had the lowest recombination rate of electron–hole pairs and charge transfer resistance to enhance the photocatalytic activity, as evidenced by PL and EIS analyses. Therefore, V-doped Mo(O,S)2 can be a potential candidate for photocatalytic degradation of organic dyes for environmental remediation.
研究领域:
环境科学
·
材料科学
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DOI
高影响因子
FirePhysChem
·
2022
·
IF 0
Kunkai Wang,Xiangzhi Li,Kaidi Yang,Huan Huo,Qi Xue,Bozhou Wang,Fuqiang Bi
1,1,4,4-Tetramethyl-2-tetrazene (TMTZ), a potential candidate for replacing 1,1-dimethylhydrazine (UDMH), has excellent properties including a high specific impulse, non-toxicity and non-volatility. However, most synthetic methods depicted in the literature use stoichiometric oxidative coupling, and the oxidizing agents are usually heavy metals or halogens, leading to low synthetic efficiency and high environmental pollution. In order to overcome these problems, it is necessary to explore more environmentally friendly and catalytic synthetic methods. In this paper, a method of photocatalytic oxidative coupling for the preparation of TMTZ was reported for the first time. By using an organic photocatalyst Eosin Y, TMTZ was synthesized rapidly and efficiently. The thermal decomposition properties of TMTZ were studied, and different performance characteristics between TMTZ and UDMH were determined and analyzed, which provided a basis for the application of TMTZ based new liquid propellant.
研究领域:
有机化学
·
催化化学
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能源材料
·
推进剂化学
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DOI
CHROMATOGRAPHIA
·
2019
·Vol. 82
·期 10
·1579-1583
·
IF 1.552
Lou Chunli,Zheng Mengmeng,Xu Yao,Shen Yuting,Kang Jingwu
A sensitive method was developed for detecting 2,2′-azobis(2-amidinopropane) dihydrochloride in polyvinylpyrrolidone by capillary electrophoresis with indirect UV detection. The detection sensitivity was improved significantly using the field-amplified sample injection technique. The background electrolyte was composed of 25 mM imidazole-HCl solution (pH 4.0), in which imidazole acted as the cation probe for the indirect detection at UV 214 nm. Effects of the experimental parameters including pH, the concentration of imidazole as well as the sample injection time on sample preconcentration were investigated and optimized. Under the optimized conditions, baseline separation of 2,2′-azobis(2-amidinopropane) ion with other ions in the polyvinylpyrrolidone samples was achieved within 8 min. The RSD% for the repeatability of the migration time and the peak area were determined as 0.95% and 3.47%, respectively. The limit of detection (LOD, S / N = 3) and the limit of quantitation (LOQ, S / N = 10) were determined as 1.11 × 10 −5 M and 2.77 × 10 −5 M, respectively. The measured recovery at three concentration levels was in the range of 101–104%. This method was successfully applied to detect 2,2′-azobis(2-amidinopropane) in the commercial polyvinylpyrrolidone samples.
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产品关联
DOI
高影响因子
CELL BIOCHEMISTRY AND BIOPHYSICS
·
2024
·
IF 1.8
Tu Jia,Liu Qiaoling,Sun Huirong,Gan Luzhen
Diabetic cardiomyopathy (DCM) is a prevalent complication of diabetes mellitus characterized by cardiac dysfunction and myocardial remodeling. Farrerol (FA), an active ingredient in Rhododendron with various pharmacological activities, has an unclear specific role in DCM. Therefore, this study aims to investigate the effects of FA on DCM rats and elucidate its mechanism. The type 2 diabetes mellitus (T2DM) model was induced in adult male Sprague-Dawley rats by administering a high-fat diet for 8 weeks along with STZ injection. Subsequent to successful modeling, FA and the positive drug Dapagliflozin (Dapa) were orally administered via gavage for an additional 8-week period. After administration, the rats’ body weight, fasting blood glucose, fasting insulin, and blood lipid profiles were quantified. Cardiac function was assessed through evaluation of cardiac function parameters, histopathological examination and measurement of myocardial enzyme markers were conducted to assess myocardial injury and fibrosis, Oil red O staining was utilized to evaluate myocardial lipid accumulation, wheat germ agglutinin (WGA) staining was used for assessing cardiomyocyte hypertrophy, and Western blot analysis was used to detect the proteins expression level of AMP-activated protein kinase (AMPK) pathway. The rat cardiomyocyte H9c2 were induced with palmitic acid to establish an in vitro cell model of myocardial lipid toxicity. Subsequently, the cells were subjected to treatment with FA and AMPK inhibitor Compound C, followed by assessment of lipid formation and expression levels of proteins related to the AMPK signaling pathway. The findings demonstrated that both FA and Dapa exhibited efficacy in ameliorating diabetic symptoms, cardiac dysfunction, myocardial fibrosis, cardiomyocyte hypertrophy, and lipid accumulation in T2DM rats. Additionally, they were found to enhance AMPK phosphorylation and PPARα expression while down-regulating CD36. Similarly, FA was observed to inhibit lipid formation in H9c2 and activate the AMPK signaling pathway. However, the improved effect of FA on lipotoxic cardiomyocytes induced by palmitic acid was partially reversed by Compound C. Therefore, the activation of the AMPK signaling pathway by FA may enhance cardiac lipid metabolism, thereby improving cardiac dysfunction and myocardial fibrosis in DCM rats.
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产品关联
DOI
PubMed
高影响因子
ADSORPTION SCIENCE & TECHNOLOGY
·
2019
·
IF 1.2
Yue Sun,Weisheng Zheng,Deqiang Yin
Two novel weakly basic anion exchange resins BNH and BN2 bearing two different functional groups was fabricated via the two-step amination of chloromethylated polystyrene-divinylbenzene beads with dibutylamine and dimethylamine. The adsorption properties of BNH and BN2 for the 2-naphthalenesulfonic acid (NSA) removal from wastewater were compared with two synthesized monofunctional anion exchange resins BN0 and BN6 (derived from dimethylamine and dibutylamine, respectively). The experimental data revealed that the adsorption process on the four resins fitted well with the pseudo-second-order kinetics equation and the equilibrium isotherms were in good agreement with the Langmuir model. Thermodynamic analyses illustrated that 2-naphthalenesulfonic acid adsorption onto resins was an endothermic and spontaneous process. Importantly, BN2 still displayed relatively high adsorption capacity in the existence of Na2SO4, indicative of an excellent selectivity for 2-naphthalenesulfonic acid over sulfate than other resins. The obtained results elucidate that BN2 could have potential industrial application in effluent disposal fields because of its superior selectivity, acceptable kinetics, and desorption capability.
研究领域:
环境科学
·
化学工程
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DOI
高影响因子
MOLECULES
·
2025
·Vol. 30
·期 11
·2400
·
IF 4.6
Ming Yuan,Huai Wang,Mingjun Yu,Sen Yao,Risheng Yao
Cisplatin (CIS) is a widely used chemotherapeutic agent that is highly effective against various cancers. However, its clinical application is frequently limited by its substantial nephrotoxic side effects. The gastrin-releasing peptide receptor (GRPR), a critical regulator in inflammatory diseases, has been identified as a promising therapeutic target. Our previous studies have demonstrated that the GRPR antagonists PD176252 and RH-1402 can mitigate CIS-induced nephrotoxicity through anti-inflammatory mechanisms. Based on these findings, we designed and synthesized a series of 2-arylpropanoic acid-L-tryptophan derivatives to enhance the therapeutic effects. Among these compounds,3mexhibited superior renal protection by significantly improving mouse renal tubular epithelial cell (mRTEC) viability from 50.2 ± 2.6% to 80.5 ± 3.9%, surpassing PD176252 (70.8 ± 1.4%) and RH-1402 (73.9 ± 3.7%). Moreover, compound3mmarkedly reduced the expression of kidney injury molecule-1 (KIM-1) and inflammatory cytokines [Tumor Necrosis Factor-α (TNF-α), Interleukin-6 (IL-6), Monocyte Chemoattractant Protein-1 (MCP-1)]. Finally, molecular docking results revealed that3mexhibited a high binding affinity for GRPR. Computational predictions using SwissADME further indicated that3mpossesses favorable drug-like properties, thereby supporting its potential as a promising candidate for mitigating CIS-induced nephrotoxicity.
研究领域:
药理学
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肿瘤学
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毒理学
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分子生物学
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DOI
PubMed
高影响因子
TALANTA
·
2021
·
IF 6.057
Huazheng Yu,Yanhong Li,Aisheng Huang
Sialic acid (SA) is a crucial component of glycoproteins and glycolipids on the cellular membrane, which is essential for maintaining the function of cell membranes, such as cell recognition and communication. Simultaneously, sialic acid plays a significant role in many physiological and pathological processes. Hence, it is urgent to develop a simple and sensitive strategy for determining sialic acid. In this work, a new metal-organic framework called UiO-66-NH 2 @B(OH) 2 has been designed and synthesized for the recognition and detection of sialic acid. The boronic acid functional group in UiO-66-NH 2 @B(OH) 2 can bind to a diol moiety of the glycerol side chain of sialic acid, which will attenuate or even quench the fluorescence of UiO-66-NH 2 @B(OH) 2 , thus opening a new road to detect sialic acid. Based on the measurement results, sialic acid can be quantitatively measured in a linear range of 0.05–2.5 mmoL/L with the UiO-66-NH 2 @B(OH) 2 probe. The detection limit of sialic acid is as low as 0.025 mmol/L. Furthermore, the boronic-acid functionalized probe UiO-66-NH 2 @B(OH) 2 displays high sensitivity and high selectivity to recognize the sialic acid in mouse serum samples. Therefore, the developed UiO-66-NH 2 @B(OH) 2 can be used as a promising probe to identify and detect sialic acid in the practical application.
研究领域:
分析化学
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生物化学
·
材料科学
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DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2018
·
IF 5.091
Peng Ye,Qiancheng Zou,Luyang An,Yi Wei,Aihua Xu,Xiaoxia Li
Due to low cost and low toxicity, manganese oxides have been extensively explored to reduce organic pollutants in wastewater via peroxymonosulfate (PMS) activation; but the development of manganese-based catalysts with facile synthesis process at low temperatures and high efficiency is still of significant practical interest. In this paper, a simple room temperature method has been successfully developed to synthesize cryptomelane-type manganese octahedral molecular sieves (OMS-2) from KMnO 4 and MnSO 4 in the presence of carbon nanotubes (CNTs). The redox reaction between amorphous manganese oxide and CNTs results the decrease of manganese valences and the formation of OMS-2 phase at a low temperature of 25 °C. The changes of synthesis time, temperature and CNTs dosage altered the characteristics of the prepared materials. Compared with CNTs, OMS-2 and other manganese oxides hybrids, the synthesized catalysts demonstrated a remarkable efficiency for PMS activation to degrade organic dyes and a superior reusability during ten successive cycles. Sulfate radicals were formed as the active species in the system from the oxidation of low valent Mn species by PMS. This study not only provides a simple method to synthesize OMS-2 at room temperature, but also improves the understanding of PMS activation on manganese-based catalysts for pollutants degradation.
研究领域:
环境科学
·
催化化学
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DOI
高影响因子
Journal of Nanoelectronics and Optoelectronics
·
2021
·Vol. 16
·期 11
·1834-1843
·
IF 0.961
Yuan Wenfeng,Yang Jia,Yuan Mengmeng,Fan Jiacheng,Li Ke,Wang Libo,Zhou Aiguo
In this paper, a novel conductive hydrogel was made by a one-pot method at 60 °C for 12 hours in one step without any cross-linking agent. The hydrogel was composited of Ti3C2 MXene nano slices, poly(vinyl alcohol) (PVA) and poly-N-(2-hydroxyethyl acrylamide)
(PHEAA), named as MXene/PVA/PHEAA hydrogel. Compared with previous methods to make MXene hydrogel, this one-pot method was facile and fast. The as-prepared hydrogel was highly stretchable with the breaking elongation of 1300% and tensile strength of 1.1 MPa. MXene nano sheets dispersed in
the hydrogel formed a three-dimensional conductive network, which increased the strength and conductivity of the gels. The conductivity changed with the gel’s deformation and could be applied as strain sensors. The strain sensors made of the hydrogels were highly stretchable, bendable
and flexible with the response range of 1%–300% and a large gauge factor of 4.23. The sensors can be applied to detect human movements such as finger bending, leg bending, water drinking. The MXene/PVA/PHEAA hydrogel made by this facile one-pot method is promising to make strain sensors
for health detection.
研究领域:
材料科学
·
生物医学工程
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DOI
高影响因子
Landslides
·
2019
·Vol. 16
·期 7
·1313-1324
·
IF 4.252
Yang Wentao,Wang Yunqi,Sun Shao,Wang Yujie,Ma Chao
Detecting slope movement before landslides occur in mountain regions is crucial for disaster reduction. In October 2018, a gigantic landslide occurred on the Jinsha River, causing dammed-lake breach flood 500 km downstream. In this work, we used 25 Sentinel-2 images from November 2015 to August 2018 to explore the capability of this high temporal resolution optical images in detecting slope movement before the Jinsha River landslide. Normalized difference vegetation index (NDVI) was calculated to composite temporal profiles using all Sentinel-2 images. With this NDVI time series, unsupervised K-means classifier was applied to initially classify the study area and find the best thresholds for automatically extracting landslide scars in the image series. These extracted landslide scars were validated using interpreted results from two high spatial resolution images of similar dates in 2015 (user’s accuracy 89.7%, producer’s accuracy 83.6%) and 2018 (user’s accuracy 90.8%, producer’s accuracy 74.9%). After validation, extracted landslide scars of different years were counted and displayed in an RGB composite image to highlight slope movement. In addition, monotonous decrease/increase of NDVI was also observed, indicating continuous expansion of landslide scarps and movement of landslide head along the slope on the landslide surface. This work demonstrated the capability of Sentinel-2 time series images to capture slope movement with short revisit time at low cost. By incorporating other environmental information (such as elevation), this proposed method has the potential to consistently map pre-landslide slope movements over a large region.
研究领域:
遥感地质学
·
环境灾害监测
·
地理信息系统
·
山地灾害防治
·
地球观测
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DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2021
·
IF 8.128
Lixia Wang,Rongfei Ye,Panming Jian,Jiangyong Liu
Metal-free catalysts with environmental friendless, cost-competitiveness and less susceptibility to leaching and poisoning over metal-based catalysts, have revolutionized in the catalysis domain. In this respect, we herein report the first application of cheap and abundant pumpkin-derived N -doped porous carbon for the reduction of 2-methyl-4-nitrophenol assisted by NaBH 4 . The obtained catalyst is cost-competitive, efficient and robust, with an attractive mass-normalized rate constant of 4.73 s −1 g −1 and good recycling performance. Systematical analyses demonstrate that the 2-methyl-4-nitrophenol reduction reaction catalyzed by the N -doped carbon proceeds through the Langmuir–Hinshelwood kinetics and the performance enhancement benefits from the strong adsorption and activation of the substrates induced by the electronic modulation in the carbon framework via N -doping. This study opens up new avenues for the high-value use of pumpkin as well as the development of metal-free strategy in more catalytic applications.
研究领域:
催化化学
·
环境科学
·
材料科学
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DOI
高影响因子
International Journal of Electrochemical Science
·
2023
·
IF 1.5
Jiao Chen,Hongye Qin,Yaping Pan,Jinli Wu,Jianan Liu,Wanying Lin,Jun Jiang,Enzuo Liu,Junwei Sha,Fang He,Liying Ma,Naiqin Zhao
It is necessary and challenging to develop platinum-based electrocatalysts with low Pt content and high performance for industrial development in a suitable strategy. Herein, ultralow Pt (0.35 wt%) loading Ni(OH) 2 nanosheets (named as 2-Pt/Ni(OH) 2 ) with cataphracted structure is synthesized on nickel foam by one-step hydrothermal process. It only needs an overpotential of 34 mV to achieve a current density of 10 mA cm -2 without any significant decrease for 40 hours. This excellent performance of hydrogen evolution reaction (HER) is attributed to the fact that the cataphracted structure not only has a larger active area and more active sites, but also effectively limits the size of Pt nanoparticles to 2~3 nm, which results in a higher active quality. In addition, the relatively simple and easily operational one-step method can reduce the Pt content to 0.35 wt% significantly. This facile strategy opens up new approaches in the rational design and synthesis of low loading Pt electrocatalysts with eminent electrocatalytic activity for industrial production.
研究领域:
材料科学
·
电化学
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DOI
高影响因子
危险品化学品经营许可证（带存储）