RENEWABLE ENERGY
·
2022
·
IF 8.634
Zhijin Zhang,Yingjie Du,Geling Kuang,Xuejian Shen,Xiaotong Jia,Ziyuan Wang,Yuxiao Feng,Shiru Jia,Fufeng Liu,Muhammad Bilal,Jiandong Cui
The production of biodiesel catalyzed by lipase has the advantages of simple process, low energy consumption, and low wastewater treatment requirements. However, low activity, poor stability, and difficulty in recycling still limit the application of lipase in production of biodiesel. Herein, a novel lipase hybrid biocatalyst with superior catalytic activity and stability (lipase from Aspergillus oryzae CJLU-3, AOCL@CaP in DES) was developed by dual activation of Ca 2+ and interfacial effect of deep-eutectic solvents (DES)/water two-phase system. AOCL@CaP in DES exhibited significantly enhanced enzymatic activity with a K cat /K m value of 692 s −1 mM −1 and excellent thermostability, tolerance to chemical denaturants, substrate selectivity, and reusability compared with free lipase. Recovery activity of the prepared hybrid biocatalyst in pure water system (AOCL@CaP) and AOCL@CaP in DES was 195% and 250% using p-NPL as substrate, respectively. AOCL@CaP in DES exhibited about 253% of the original activity after 100 days of storage, while free AOCL, AOCL@CaP almost completely lost activity. The FAME content in product biodiesel catalyzed from soybean oil by AOCL@CaP was only 60%, However, the FAME content catalyzed by AOCL@CaP in DES reached 87%, and could be maintained at 50% even after 10 cycles.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Ziyao He,Xiaojuan Liang,Weidong Xiang
All-inorganic halide perovskite nanocrystals (NCs) have become the most promising next generation luminescent materials due to their excellent properties. However, there are many nonradiative recombination defects in colloidal perovskite NCs, which reduce their luminescent efficiency and stability. In this work, we incorporated the alkaline-earth (AE) metal ion Ca 2+ into NCs to further improve the photoluminescence quantum yield (PLQY) of CsPbBr 3 and CsPbBr 1 I 2 NCs. The PLQY of green-emitting CsPbBr 3 and red-emitting CsPbBr 1 I 2 NCs can be boosted to 72.3% and 78.7%, respectively by doping the optimum amount of Ca 2+ . At the same time, we adopted a simple and low-cost one-pot method to integrate Ca 2+ -CsPbX 3 (X 3 = Br 3 , Br 1 I 2 ) NCs and superhydrophobic silica aerogels (AG), not only retaining the high PLQY of NCs, but also greatly improving the water, heat and light stability. Finally, the green-emitting Ca 2+ -CsPbBr 3 @AG, red-emitting Ca 2+ -CsPbBr 1 I 2 @AG composites and the blue chip as the light sources show a wide color gamut that accounts for 129% of the NTCS 1953 value and nearly 100% of the Rec.2020 value. Additionally, we fabricated white light-emitting diode (WLED) devices by coupling Ca 2+ -CsPbBr 1 I 2 @AG composites with commercial YAG:Ce 3+ phosphors on blue chips, obtaining bright white light with a color rendering index (CRI) up to 92.2.
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高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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2020
·
IF 6.155
Shao-Fang Li,Zhen-Yi Gu,Jin-Zhi Guo,Xian-Kun Hou,Xu Yang,Bo Zhao,Xing-Long Wu
In recent years, sodium-ion batteries (SIBs) have been considered as one of the most promising alternatives to lithium-ion batteries (LIBs). Here, a new Na-super-ionic conductor (NASICON) cathode material NaFe 2 PO 4 (SO 4 ) 2 is successfully prepared through solid state method for SIBs. While the poor electronic conductivity of iron-based materials results in its poor rate and cycle performance. Then the electrochemical is effectively promoting via Ca 2+ doping. Na 0.84 Ca 0.08 Fe 2 PO 4 (SO 4 ) 2 have achieved considerable electrochemical properties. The first discharge specific capacity is 121.6 mA h g −1 at 25 mA g −1 with the voltage platform (∼3.1 V) corresponding to Fe 2+/3+ . After 100 cycles, the capacity retention is 55.1 %. The excellent electrochemical performance is caused by some Na + is substituted by Ca 2+ and leading to the fast sodium kinetics, which is well proved by the powder X-ray diffraction pattern and well corresponding to the galvanostatic intermittent titration technique and cyclic voltammetry testing result (the diffusivity values are around at 10 −12 cm 2 s −1 ).
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高影响因子
AIP Advances
·
2024
·Vol. 14
·期 8
·
IF 1.4
Zheng Yu,Song Rujuan,Wei Shengjie,Dong Lei,Chen Yazhou
Long-term potentiation (LTP) in the Schaffer-CA1 region of the hippocampus is closely related to learning and memory. Magnetic stimulation, as an effective physical means of regulating synaptic plasticity, has received widespread attention. However, research on the mechanism of the effect of different frequencies of magnetic fields (MFs) on LTP is relatively scarce. This article focuses on Ca 2+ , Na + , K + , NMDA receptors, and AMPA receptors that play important roles in the process of MF regulation of LTP. A combined electrophysiological and pharmacological approach was used to identify Ca 2+ as a key factor in the modulation of LTP by MFs of different frequencies. Subsequently, further experiments revealed that low levels of intracellular Ca 2+ concentration ([Ca 2+ ] i ) intensified the inhibition of low-frequency MFs on LTP, while high levels of [Ca 2+ ] i enhanced the promotion effect of high-frequency MFs on LTP, indicating a positive correlation between [Ca 2+ ] i levels and MF regulation of LTP levels. The research results of this article may help explore the deeper relationship between different frequencies of MFs and synaptic plasticity, and they also have a certain reference value for magnetic stimulation therapy in the treatment of neurological diseases related to LTP injury or learning and memory deficits.
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高影响因子
APPLIED SURFACE SCIENCE
·
2025
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IF 6.9
Songfeng E,Yuan Wang,Yuanming Wang,Jiaming Yang,Junli Ma,Kaiyue Huang,Zhangzi Li,Zhaoqing Lu,Lejia Wang
We discovered that incorporating the Ca 2+ into sodium alginate (SA) solution as ball-milling medium of hexagonal boron nitride ( h -BN) could increase the lateral size of the exfoliated h -BN nanosheets (BNNSs) at least twice those of pure SA solution obtained, which can be owing to the Ca 2+ −induced crosslinking of SA and enhancement of interfacial adhesion forces between SA and h -BN that not only boost the impacting resistance to milling balls but also the exfoliation energy to h -BN. Based on the crucial role of Ca 2+ in h -BN exfoliation, the large-area and small-thickness BNNSs are produced simultaneously with the increased milling speed and Ca 2+ concentration, which can be assembled into highly compact and horizontal oriented structures with aramid nanofibers (ANFs) due to the favorable compatibility, dispersity, and interfacial binding force. This kind of compact and ordered structure enables ANF/BNNS film with high thermal conductivity (TC) since the connective and high-efficiency heat conduction paths, of which the highest TC is 27.57 W⋅m −1 ⋅K -1 . Compared with soft and molecular SA chains, the ANFs show an incredible ability to guide the horizontal orientation of BNNSs for the superior TCs of their composites.
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高影响因子
Light-Science & Applications
·
2022
·Vol. 11
·期 1
·1-10
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IF 20.257
Liu Dongjie,Li Guogang,Dang Peipei,Zhang Qianqian,Wei Yi,Qiu Lei,Molokeev Maxim S.,Lian Hongzhou,Shang Mengmeng,Lin Jun
Near-infrared (NIR)-emitting phosphor-converted light-emitting diodes have attracted widespread attention in various applications based on NIR spectroscopy. Except for typical Cr 3+ -activated NIR-emitting phosphors, next-generation Cr 3+ -free NIR-emitting phosphors with high efficiency and tunable optical properties are highly desired to enrich the types of NIR luminescent materials for different application fields. Here, we report the Fe 3+ -activated Sr 2− y Ca y (InSb) 1− z Sn 2 z O 6 phosphors that exhibit unprecedented long-wavelength NIR emission. The overall emission tuning from 885 to 1005 nm with broadened full-width at half maximum from 108 to 146 nm was realized through a crystallographic site engineering strategy. The NIR emission was significantly enhanced after complete Ca 2+ incorporation owing to the substitution-induced lower symmetry of the Fe 3+ sites. The Ca 2 InSbO 6 :Fe 3+ phosphor peaking at 935 nm showed an ultra-high internal quantum efficiency of 87%. The as-synthesized emission-tunable phosphors demonstrated great potential for NIR spectroscopy detection. This work initiates the development of efficient Fe 3+ -activated broadband NIR-emitting phosphors and opens up a new avenue for designing NIR-emitting phosphor materials.
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
·
IF 8.5
Yige Chen,Qiaoyu Huang,Man Zhou,Yong Hu,Yuhong Zhang,Xueliang Jiang,Zhaoxia Chen
Conductive hydrogels have demonstrated great potential in flexible wearable sensors due to their excellent flexibility and conductivity. Nevertheless, traditional hydrogels suffer from limitations such as weak mechanical properties, inadequate fatigue resistance, and lack of recyclability, which have hindered their practical applications. In this study, a polyvinyl alcohol/polyacrylamide/κ-carrageenan-Ca 2+ /K + (PPK-Ca 2+ /K + ) composite hydrogel was developed by constructing a dynamic network structure involving hydrogen bonds, electrostatic interactions, and synergistic co-crosslinking of Ca 2+ /K + . The resulting ionic conductive hydrogel exhibited remarkable stretchability (~ 414 %), high tensile strength (1190 kPa), and excellent fatigue resistance. Benefiting from the negatively charged κ-carrageenan and the ion transport co-regulation by Ca 2+ /K + , the hydrogel achieved a high ionic conductivity of 7.26 mS/cm. Moreover, owing to the thermoreversible properties of κ-carrageenan and PVA, the hydrogel material could be recycled through high-temperature remolding processes. The flexible sensor assembled with PPK-Ca 2+ /K + hydrogel demonstrated high sensitivity, a broad detection range (0–400 %), and rapid response time (152 ms), enabling precise monitoring of various human activities, ranging from large joint movements to subtle muscle contractions. The proposed fabrication strategy for robust, fatigue-resistant, self-healing, and recyclable conductive hydrogel provides new insights for developing high-performance wearable sensors and electronic skin.
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DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2018
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IF 6.434
Jun Hou,Hanlin Ci,Peifang Wang,Chao Wang,Bowen Lv,Lingzhan Miao,Guoxiang You
The effect of Ca 2+ and alginate on the stability of CeO 2 nanoparticles (NPs) was investigated using dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA); the two methods were then compared. DLS showed rapid aggregation of CeO 2 NPs in 8 mM Ca 2+ solution; however, NTA showed that some primary aggregates (200–400 nm) still remained—a result that was obscured in DLS measurements. Aggregation of alginate molecules was also studied using DLS and NTA, where NTA particle concentration and video provided additional information on the alginate aggregation progress. Finally, DLS showed that in the presence of alginate, the aggregation rate and size of CeO 2 NPs increased. NTA intensity measurements provided insight into a heteroaggregation and bridging mechanism. NTA particle concentration and video also showed CeO 2 NPs were linked by alginate gel in high Ca 2+ concentration (>4 mM). the DLS and NTA had different advantages in measuring particle size. DLS could better study the initial aggregation stage and large aggregates, while NTA could better detect small aggregates. NTA also measured particle number concentration, individual intensity, and particle motion video, which provided additional insight. Combining these two methods could help us to better understand the behavior and fate of NPs in water.
研究领域:
环境科学
·
纳米技术
·
化学
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高影响因子
JOURNAL OF ETHNOPHARMACOLOGY
·
2026
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IF 6.8
Chunlai Wang,Xiao Xu,Haoyun Zhu,Dengyu Wu,Jianing Liang,Xiangxiang Wang,Ruoxi Song,Liangye Shen,Yuhang Hu,Dechang Wang,Haoru Zhu,Xinhui Cheng,Yu Qi
Ethnopharmacological relevance Effective activation of neuronal autophagy and clearance of amyloid-beta (Aβ) represents a promising therapeutic strategy in the treatment of Alzheimer's disease (AD). The Acori Tatarinowii Rhizoma-Curcumae Radix Herbal pair (ACHP), derived from the traditional Changpu Yujin Decoction, has a long history in Traditional Chinese Medicine for addressing conditions related to cognitive function. However, the precise mechanisms underlying its role in autophagic dysfunction-related dementia remain unclear. Aim of the study This study aims to investigate the neuroprotective effects of ACHP and the underlying mechanisms in AD. Materials and methods Analysis of prototype constituents in drug-containing serum was performed using UHPLC-Triple-TOF/MS. The neuroprotective effects of ACHP were evaluated in APP/PS1 mice using behavioral tests, including the Y-maze and Morris water maze. Transcriptomic analysis was conducted to identify potential neuroprotective pathways activated by ACHP. Neuronal damage and structural recovery were assessed through HE and Nissl staining. In addition, the anti-inflammatory and autophagy-regulating effects of ACHP were further investigated in N2a/APP cells. The molecular mechanisms were further elucidated using Western blot, immunofluorescence, ELISA, and qRT-PCR in both in vivo and in vitro models. Results Twenty-five compounds in ACHP-treated mouse serum were identified. ACHP improved spatial learning and memory performance, increased intracellular Ca 2+ levels and downregulated the expressions of proinflammatory cytokines, including TNF-α, IL-1β, and IL-6, while significantly promoting autophagy. ACHP increased CaMKKβ protein expression and activated the AMPK signaling pathway (elevated p-AMPK/AMPK ratio), as well as those of autophagy-related proteins, while improving neuronal morphology. Conclusion These findings indicate that ACHP alleviates neuro-inflammatory damage and cognitive impairment potentially through modulation of the Ca 2+ /CaMKKβ–AMPK–mTOR signaling pathway involved in autophagy.
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PubMed
高影响因子
MINERALS ENGINEERING
·
2026
·
IF 6
Xuefei Zhang,Siwei Zhuang,Lujun Wang,Guowei Han,Yalei Zhang,Fanfei Min
Complexation color development-infrared spectroscopy (CCDIR) measures Ca 2+ directly. • CCDIR remains linear at 10 ∼ 150 mg/L Ca 2+ , unlike visible spectrophotometry. • CCDIR achieves a 0.354 mg/L detection limit and 96 ∼ 104% recoveries. • The infrared response of CCDIR method remains measurable from pH 3 to 12. • This method exhibits strong anti-interference ability to Na⁺ and K⁺. Conventional complexation color development-visible spectrophotometry (CCDVS) is limited for direct determination of high-concentration Ca 2+ in mineral-processing circulating water because it becomes nonlinear at high concentrations. To address this limitation, this study integrates complexation color development with infrared spectroscopy and proposes a novel detection approach, complexation color development-infrared spectroscopy (CCDIR). At pH = 11, CCDIR was linear over 0 ∼ 10 mg/L (T = 0.1328C + 2.3903, R 2 = 0.999) and 10 ∼ 150 mg/L (T = 0.0246C + 3.5370, R 2 = 0.999), whereas CCDVS was linear only at 0–10 mg/L (A = -0.1265C-0.0579, R 2 = 0.993) and presented a nonlinear model at 10 ∼ 150 mg /L. The limits of detection were 0.354 and 0.372 mg/L for CCDIR and CCDVS, respectively. Across the CCDIR samples studied, relative error and relative standard deviation remained below 4%, corresponding to recoveries of 96 ∼ 104%. CCDVS relies on a specific pH (pH = 11), and pH fluctuations significantly reduce its accuracy. In contrast, CCDIR shows a wider pH adaptation window (3 ∼ 12), offering greater environmental adaptability and stability. A comparison of the calibration slopes revealed that CCDIR offered a more stable and predictable response over its extended linear range compared to the limited linear range and subsequent nonlinear behavior of CCDVS. At 150 mg/L, 20 mg/L Na + and K + changed the visible signal by only 0.36% and 0.32%, respectively, whereas Mg 2+ produced measurable interference. CCDIR technology provides technical support for accurate determination of high-concentration Ca 2+ in mineral processing wastewater, as well as data support for rapid detection of metal ions in coal washing and processing processes.
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高影响因子
Antioxidants
·
2025
·Vol. 14
·期 4
·490
·
IF 6.6
Chao Ma,Yu Nie,Donglei Zhang,Lulu Ran,Su Xu,Xun Ran,Junya Huang,Lingshuai Meng
Background: Blueberry anthocyanin such as Cyanidin-3-O-glucoside may help prevent Alzheimer’s disease. We aimed to investigate the preventive and therapeutic effects of Cyanidin-3-O-glucoside against Aβ1–42-induced apoptosis of SH-SY5Y cells as well as the underlying mechanisms. Methods: Cell viability and intracellular and mitochondrial reactive oxygen species were detected by MTT, a reactive oxygen species detection kit, and a MitoSOX red mitochondrial superoxide indicator. The mitochondrial membrane potential, intracellular calcium ion content, and adenotriphophate (ATP) were identified via a mitochondrial membrane potential detection kit, calcium ion detection kit, and ATP detection kit, and apoptosis was detected via flow cytometry. Transcription of apoptosis-related genes was detected using real-time fluorescence quantitative polymerase chain reaction, and expression of apoptosis-related proteins was identified using Western blot. Results: We found that Cyanidin-3-O-glucoside could downregulate the expression of cytochrome c, caspase 9, caspase 3, and other genes and proteins, which consequently reduced the rate of apoptosis. Additionally, it could upregulate Bcl-2 gene and protein expression, downregulate Bax gene and protein expression, regulate mitochondrial membrane permeability and calcium-release channels, reduce calcium influx into mitochondria, maintain intracellular calcium ion levels, reduce intracellular levels of reactive oxygen species and increase ATP levels, maintain the mitochondrial membrane potential at a normal level, maintain normal mitochondrial functioning, and prevent apoptosis. Discussion: Taken together, Cyanidin-3-O-glucoside showed dose-dependent preventive and therapeutic effects against Aβ1–42-induced apoptosis of SH-SY5Y cells. Conclusions: Cyanidin 3-O-glucoside showed a better preventive effect than therapeutic effect against Aβ1–42-induced apoptosis in SH-SY5Y cells.
研究领域:
神经生物学
·
药理学
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PubMed
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Ling-Zhi Liu,Rui Zhou,Yong-Li Li,Yue-Hong Pang,Xiao-Fang Shen,Jun Liu
Neonicotinoids, the fastest-growing class of insecticides, have posed a multi-media residue problem with adverse effects on environment, biodiversity and human health. Herein, covalent organic framework-sodium alginate-Ca 2+ -polyacrylic acid composite beads (CACPs), facilely prepared at room temperature, were used in convenient dispersive solid-phase extraction (dSPE) and combined with high-performance liquid chromatography (HPLC) for the detection of five neonicotinoid insecticides (thiamethoxam, acetamiprid, dinotefuran, clothianidin, imidacloprid). CACPs can be completely separated within 1 min without centrifugation. After seven adsorption/desorption cycles, it maintained high extraction efficiencies (>90%). The developed method exhibited a wide linear range (0.01 ∼ 10 μg mL −1 ), low limits of detection (LODs, 0.0028 ∼ 0.0031 mg kg −1 ), and good repeatability (RSD ≤ 8.11%, n = 3). Moreover, it was applied to the determination of five neonicotinoids in fruit and vegetables (peach, pear, lettuce, cucumber, tomato), and recoveries ranged from 73.6% to 116.2%.
研究领域:
分析化学
·
环境科学
·
食品安全
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PubMed
高影响因子
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