Metabolomics
·
2022
·Vol. 18
·期 11
·1-14
·
IF 4.747
Li Yongyu,Tian Sicheng,Yang Le,Bao Xiaoming,Su Lin,Zhang Xiang,Liu Sijing,Zhu Yalan,Yang Jiaxue,Lin Hua,Zhang Jing,Zeng Jumei,Wang Chuan,Tang Tian
Introduction Previous reports revealed the role played by Salmonella PhoP–PhoQ system in virulence activation, antimicrobial tolerance and intracellular survival, the impact of PhoP–PhoQ on cell metabolism has been less extensively described. Objectives The aim of this study is to address whether and how the PhoP–PhoQ system affects the cell metabolism of Salmonella. Methods We constructed a Salmonella phoP deletion mutant strain TT-81 (PhoP-OFF), a Salmonella PhoP constitutively expressed strain TT-82 (PhoP-ON) and a wild-type Salmonella PhoP strain TT-80 (PhoP-N), using P22-mediated generalized transduction or λ Red-mediated targeted mutagenesis. We then measured the in vitro growth kinetics of all test strains and determined their metabolomic and transcriptomic profiles using gas chromatography coupled with tandem mass spectrometry (GC–MS/MS) and RNA-seq technique, respectively. Results Low-Mg 2+ conditions impaired the growth of the phoP deletion mutant strain TT-81 (PhoP-OFF) dramatically. 42 metabolites in the wild-type PhoP strain TT-80 (PhoP-N) and 28 metabolites in the PhoP constitutively expressed strain TT-82 (PhoP-ON) changed by the absence of phoP . In contrast, the level of 19 compounds in TT-80 (PhoP-N) changed comparing to the PhoP constitutively expressed strain TT-82 (PhoP-N). The mRNA level of 95 genes in TT-80 (PhoP-N) changed when phoP was disrupted, wherein 78 genes downregulated and 17 genes upregulated. 106 genes were determined to be differentially expressed between TT-81 (PhoP-OFF) and TT-82 (PhoP-ON). While only 16 genes were found to differentially expressed between TT-82 (PhoP-ON) and TT-80 (PhoP-N). Conclusion Our findings confirmed the impact of PhoP–PhoQ system on lipopolysaccharide (LPS) modification, energy metabolism, and the biosynthesis or transport of amino acids. Most importantly, we demonstrated that the turnover of a given metabolite could respond differentially to the level of phoP . Taken together, the present study provided new insights into the adaptation of Salmonella to the host environment and helped to characterize the impact of the PhoP–PhoQ system on the cell metabolism.
研究领域:
微生物学
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分子生物学
·
系统生物学
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DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2020
·
IF 3.83
Yongli Zhang,Minghui Li,Zihui Kong,Chao Liang,Cheng Zhou,Mao Xia,Zhi Zhou
Outdoor lighting and other lighting systems can disrupt natural plant growth habits. Thus, LED lighting that is not detrimental to plant growth is required. In our study, Dy 3+ -doped Ca 8 ZnY(PO 4 ) 7 :Dy 3+ phosphor with enhanced luminescence properties caused by the co-dopants Mg 2+ and B 3+ were synthesised. The samples had multiple excitation peaks, indicating they are excited by either near-ultraviolet (n-UV) or blue chips. All samples exhibited bright narrow yellow and blue emission corresponding to the transitions of Dy 3+ ions with 4 F 9/2 → 6 H 13/2 and 4 F 9/2 → 6 H 13/2 , respectively. Moreover, doping with Mg 2+ and B 3+ enhanced the luminescence intensity, reaching 113.6 and 119.7%, respectively. In addition, the luminescence emission intensity at 150 °C was maintained at approximately 95% of the initial value at 25 °C, and its thermal stability increased by 123%. Devices assembled with an n-UV chip (388 nm) and the as-obtained CZMYP:Dy 3+ phosphor emitted a bright warm white light and simulated outdoor dark lighting for tobacco cultivation, indicating that the as-prepared phosphor is an excellent candidate material for plant habitat-conscious phosphors.
研究领域:
材料科学
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发光材料
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固态照明
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光学性质
·
植物生理与照明
✓ 已验证
DOI
高影响因子
Journal of Physical Chemistry C
·
2021
·
IF 4.126
Di Wu,Wen Ren,Yang Yang,Jiulin Wang,Yanna NuLi
A magnesium–sulfur (Mg–S) battery system is considered a high-performance candidate for next-generation secondary batteries, because of its prominent advantages such as high safety, low cost, and high energy density. However, the shuttle effect caused by the dissolution of polysulfides leads to irreversible loss of capacity. Herein, we prepare a S0.96Se0.04@CMK3 composite (with a high S + Se content of 82.6 wt %) and employ the composite material as a cathode for Mg batteries with easily prepared hybrid electrolytes. The electronic conductivity of the cathode material increases by 18 orders of magnitude after Se doping, from 5 × 10–28 to 6.5 × 10–10 S m–1. Compared with S@CMK3, doped Se in S0.96Se0.04@CMK3 plays an important role in maintaining capacity stability by lowering polarization, facilitating electron transport, and improving reaction kinetics. The S0.96Se0.04@CMK3 cathode delivers a stable and reversible capacity of 492.9 mAh g–1 after 110 cycles, which is almost twice that of the S@CMK cathode without Se doping, and better rate performance. This Se-doping strategy proposes an effective method to exploit high-performance cathodes for Mg–S batteries.
研究领域:
电化学
·
能源材料
·
无机化学
·
纳米材料
·
二次电池
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2019
·
IF 4.175
Qinghong Meng,Ji-Guang Li,Qi Zhu,Xiaodong Li,Xudong Sun
A series of phase-pure [(Gd 0.6 Lu 0.4 ) 1- y Ce y ] 3 [Al 1- z (Mg/Si) z ] 5 O 12 ( y = 0–0.012, z = 0–0.15) garnet phosphors were synthesized via gel-combustion, and the effects of Mg 2+ /Si 4+ substitution on characteristics of the garnet host and Ce 3+ luminescence were investigated in detail. The maximum amount of equimolar Mg 2+ /Si 4+ dopants that can be incorporated into the garnet lattice and the optimal Ce 3+ content for luminescence were determined to be around z = 0.15 and y = 0.010, respectively. Mg 2+ /Si 4+ codoping was analyzed to narrow bandgap of the host, non-uniformly compress the [CeO 8 ] dodecahedron , enlarge the [Al-O] polyhedrons and meanwhile alter bond angles. Increasing Mg 2+ /Si 4+ content was found to lower the intensity, fluorescence lifetime and thermal stability of Ce 3+ luminescence and meanwhile red-shift the 4f-5d 1 excitation/emission peaks. The results were interpreted by considering band structure and crystal field splitting of the Ce 3+ 5d energy level. The y = 0.01 and z = 0.15 phosphor exhibited a broad emission peaked at ∼561 nm under 457 nm excitation, with CIE color coordinates of around (0.449,0.527), a correlated color temperature of ∼3567 K, a fluorescence lifetime of ∼43 ns, and an activation energy for thermal quenching of ∼0.267 eV. Electroluminescence indicated that the phosphors may find potential application in warm-white LEDs excited by blue-LED chips.
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DOI
高影响因子
JOURNAL OF LUMINESCENCE
·
2023
·
IF 3.6
Liwei Zeng,Jiyou Zhong,Wenbin Lin,Weiren Zhao
NIR phosphor-converted light-emitting diode (NIR pc-LED) has attracted many attentions for its promising applications in biomedical imaging, night vision, spectroscopy, and many other fields, while the discovery of broadband NIR phosphors with high external quantum efficiency (EQE) remains a challenge. Herein, a series of efficient and tunable broadband NIR-emitting Ga 1.97-2 x Mg x Sn x O 3 :0.03Cr 3+ phosphors were synthesized via [Mg 2+ -Sn 4+ ] substituting [Ga 3+ -Ga 3+ ] in Ga 2 O 3 :Cr 3+ system. As increase of substituting ratio x , a significant red-shift in the emission spectra from 726 to 793 nm with a full width at half maximum (FWHM) extended from 121 to 167 nm can be observed. All the samples have an EQE above 40% under 450 nm excitation; and the excitation peak in the blue light region remains unchanged, enabling these materials to be efficiently excited by blue LEDs. Finally, a NIR pc-LED device was fabricated by integrating the optimized Ga 1.77 Mg 0·1 Sn 0·1 O 3 :0.03Cr 3+ phosphor on a blue LED chip, which exhibits a high NIR output power of 33.41 mW with a photoelectric conversion efficiency of 12.01% under a drive current of 100 mA. These results indicate that the obtained NIR phosphors may have potential in NIR pc-LEDs applications.
研究领域:
材料科学
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光学材料
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固态照明
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光子学
·
发光材料
✓ 已验证
DOI
高影响因子
DESALINATION
·
2026
·
IF 9.9
Xin Shi,Qiuyan Bi,Zizhen Peng,Zhicheng Wang,Yakai Lin,Wenzhong Ma,Chuanjie Fang,Chao Zhang,Shiai Xu
In situ SiO 2 growth with DA-g-C 3 N 4 co-doping yields hybrid crosslinked PA layer. • Compound strategy mitigates DA-g-C 3 N 4 aggregation in PA layer. • Achieved simultaneous gains in Mg 2+ /Li + selectivity and permeability performance. • MgCl 2 rejection stayed >93% over 160 h, demonstrating excellent long-term stability. It is often difficult for thin-film composite (TFC) nanofiltration (NF) membranes to balance high separation selectivity and high permeability, and the contradiction between the two will lead to their overall performance constraints. In this study, a dual-phase regulation strategy is proposed, which adopts the in-situ sol method and the composite strategy of introducing two-dimensional materials for the preparation of organic-inorganic cross-linked polyamide (PA) NF membranes. A trimesoyl chloride (TMC) organic phase solution containing tetraethyl orthosilicate was first introduced onto the polyethersulfone (PES) substrate, followed by contact with a polyethyleneimine (PEI) aqueous phase solution containing dopamine-functionalized carbon nitride (DA-g-C 3 N 4 ), during which silicon dioxide (SiO 2 )/Si–O–Si domains were generated in situ within the PA layer. These domains restricted the free volume of the PA layer, narrowed the effective pore-size distribution, and suppressed nonselective defects, while the embedded DA-g-C 3 N 4 improved the compatibility between the nanofillers and the PA layer, thereby producing P-1Si-0.025CN membranes with an effective pore size of 0.4 nm. Compared with the P-NF membrane prepared by reverse interfacial polymerization of TMC and PEI directly on the PES substrate, Mg 2+ /Li + separation factor (SF) increased to 67.2 (Mg 2+ /Li + mass ratio is 20), salt solution flux was 27.1 LMH, separation and permeation capacity of mixed salt was enhanced, salt solution flux has increased by 4 times, and the SF has increased by 7 times, Mg 2+ /Li + ratio decreased from 20 in feed to 0.71 in permeation process. Moreover, it exhibited excellent separation performance in diluted salt lake brine, with an Mg 2+ rejection rate exceeding 98%, and it also exhibited high fouling resistance and long-term stability. Download: Download high-res image (155KB) Download: Download full-size image
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产品关联
DOI
高影响因子
JOURNAL OF CRYSTAL GROWTH
·
2025
·
IF 2
Yisong Yang,Sha Chen,Zhishun Wei,Ying Chang,Yan Xiong,Junxiang Zhao,Hu Zhu,Min Li,Qirui Yang,Guoqiang Yi
This study proposes a method involving stirring after a constant-temperature water bath in a salt solution to enhance the crystal size, overall homogeneity, and hydration strength of α-hemihydrate gypsum (α-HH). Utilizing by-product gypsum from the chlor-alkali industry as raw material, the influence of Mg 2+ ions on phase evolution and final morphology was systematically investigated. During the constant-temperature water bath process in salt solution, the neutral MgSO 4 0 ion pairs formed by Mg 2+ and SO 4 2- facilitated the dissolution of dihydrate gypsum (DH) while amplifying the solubility difference between α-HH and DH, thereby promoting preferential crystallization and precipitation of α-HH. Furthermore, Mg 2+ inhibited crystal growth along the c-axis direction during α-HH development, effectively reducing the aspect ratio. The subsequent stirring process significantly increased secondary nucleation probability, enabling mutual adhesion among α-HH crystals of varying dimensions. This synergistic process ultimately yielded enlarged α-HH crystals with an average particle size of 143.21 μm and aspect ratio of 5.57. The flexural strength and absolute dry compressive strength of bulk samples prepared from these α-HH crystals are discussed in detail, demonstrating substantial improvements in mechanical properties compared to conventional preparation methods.
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产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2025
·
IF 9
Cuijing Liu,Lei Li,Linbo Li,Xihong He,Hideto Matsuyama
Covalent organic framework (COF) emerges as a promising membrane material for ion separation, such as Li + extraction from brines. However, the single-functionalization of most COF channels hinders further improvements in separation efficiency. Herein, the angstrom size, positive charge and Li + affinitive sites have been integrated in the channels of triaminoguanidine (TG)-based COF membranes. Aldehydes with different lengths of oxygen-containing side chains were employed to precisely tune the size and ion affinity of the channels. Precisely engineered cationic channels with moderate pore size and Li + affinitive sites enable Mg 2+ rejection through synergistic size exclusion and Donnan exclusion, while simultaneously accelerating Li + permeation via affinitive interactions. The optimized membrane, TG-1, achieves a remarkable Li + /Mg 2+ selectivity of 423 with a Li + permeation rate of 34.02 mmol m -2 h -1 . Additionally, TG-1 is able to perform well in practical conditions including high Mg 2+ /Li + mass ratio, high temperature, long operation time and also in various mono-/divalent metals separations. This study offers insights in the construction of multi-functional membrane channels for efficient ion separations.
研究领域:
材料科学
·
化学工程
·
分离技术
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产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Xin Zhang,Licai Chen,Yunliang Zhao,Yupeng Sun,Renbo Gao,Yanhui Miao,Shuai Cheng,Songliang Ma,Haoyu Bai,Tingting Zhang
Interfacial polymerization (IP) is a common approach for preparing selective nanofiltration (NF) membranes for efficient lithium extraction from salt-lake brines, yet controlling the structure and thickness of the polyamide (PA) selective layer remains challenging. In this study, a two-dimensional montmorillonite (2D MMT) layer was incorporated into the IP process to regulate interfacial reaction behavior. The 2D MMT layer was conducive to enriching amine monomers and inhibiting diffusion rate, thereby resulting in a thinner PA selective layer and the reduced water transport resistance. At the same time, the increased density of amine groups on the membrane surface implied that the membrane has a higher positively charge, which is more favorable for the Mg 2+ /Li + selective separation. As-optimized 2D MMT modified PA membrane demonstrated a high Mg 2+ /Li + selectivity of 35.45, nearly 6 times as high as that of the bare PA membrane. In addition, the stronger hydrophilicity of the 2D MMT modified PA membrane effectively retarded contamination, contributing to the long-term operational stability of the membrane and prolonging service life. This work provides a versatile strategy for enhancing NF membrane performance by employing 2D clay nanosheets to modulate the IP process. As-modified 2DMMT-PA membrane is suitable for practical applications in sustainable lithium resource recovery.
研究领域:
膜科学
·
材料工程
·
分离技术
·
环境工程
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2025
·
IF 5.6
Qian Zhang,Xinwen Li,Kang Chen,Ying Hu,Rongmei Liu,Guixiang Qian,Zhongliang Tian,Chao Yang
This study presents a FePO 4 -Zn/Pt hybrid power battery system designed for lithium extraction from salt lake brines. Initially, the FePO 4 -Zn battery is utilized for lithium intercalation to form LiFePO 4 , which is subsequently reassembled into a LiFePO 4 -Pt battery for lithium deintercalation. As a result, a Li + -rich aqueous solution, free from interfering metal cations, is obtained. The system eliminates the need for ion-exchange membranes, as the Pt electrode remains separated from the brine, thereby preventing contamination by impurity cations. When applied to a brine containing 0.25 g/L Li + and 73 g/L Mg 2+ , followed by desorption in a solution of 0.25 g/L Li + , only a minimal amount of Mg 2+ was transferred to the lithium chloride solution after two cycles, achieving effective lithium extraction and enrichment with an efficiency of 80.6%.
研究领域:
电化学
·
能源材料
·
环境工程
·
分离科学
·
无机化学
·
资源循环利用
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2016
·
IF 4.803
Xue Bai,Wen Li,Aijia Wei,Xiaohui Li,Lihui Zhang,Zhenfa Liu
Spinel Li 4 Ti 5 O 12 co-doped with Mg 2+ and F − was synthesized by solid-state reaction of anatase TiO 2 , Li 2 CO 3 , NH 4 F, and Mg(NO 3 ) 2 . For comparison, Mg 2+ -doped and F − -doped Li 4 Ti 5 O 12 were prepared using the same method. The structure and electrochemical performance of the prepared materials were investigated by X-ray diffraction, scanning electron microscopy, energy dispersive X-ray spectroscopy, high-resolution transmission electron microscopy, electrochemical impedance spectroscopy, and galvanostatic charge-discharge tests. Using an internal standard and Rietveld refinement, we calculated the lattice parameters of the samples. After co-doping with Mg 2+ and F − , the dopant ions enter the Li 4 Ti 5 O 12 lattice, resulting in the reduction of Ti 4+ to Ti 3+ , and increasing the conductivity of the material. Furthermore, the Mg 2+ and F − co-doping technique resulted in smaller primary particles with a narrow size distribution, factors that can accelerate transfer of Li + between the electrode and electrolyte. Consequently, the Mg 2+ and F − co-doped Li 4 Ti 5 O 12 material exhibits a superior rate performance and delivers discharge capacities of 159.4, 154.1, 146.5, 120.8, 102.7, and 76 mAh g −1 at 0.2C, 0.5C, 1C, 3C, 5C, and 10C, respectively, significantly higher than those of pure Li 4 Ti 5 O 12 (155.4, 138.6, 124.2, 94.1, 76.7, and 52.2 mAh g −1 at the same C-rates). Moreover, the Mg 2+ and F − co-doped Li 4 Ti 5 O 12 showed outstanding cycling stability, and the capacity retention was 99.62% after 150 cycles at 5C rate. Therefore, the Mg 2+ and F − co-doping technique has proven an effective approach to improve the electrochemical performance of Li 4 Ti 5 O 12 .
研究领域:
材料科学
·
电化学
·
储能技术
·
锂离子电池
✓ 已验证
DOI
高影响因子
Journal of Energy Storage
·
2025
·
IF 9.8
Yue Yu,Yujiao Guo,Ping Ning,Haibibu Aziguli
The spinel LiMn 2 O 4 is considered a promising cathode option material because it provides three-dimensional pathways for Li-ion diffusion. However, LiMn 2 O 4 exhibits insufficient rate capabilities and rapid structural deterioration during prolonged cycling, particularly under conditions of high current or elevated temperatures. Herein, we introduce a Mg 2+ /Al 3+ co-doping strategy to evade these problems. As a result, the co-doping of Mg 2+ and Al 3+ facilitates the development of a polyhedral morphology, enhancing both structural stability and rapid Li-ion diffusion. Furthermore, the incorporation of Mg 2+ and Al 3+ , which have a stable electronic configuration, enhances structural stability through their relatively stronger Mg O and Al O bonds compared to the Mn O bond. Therefore, the LiMg 0.02 Al 0.08 Mn 1.90 O 4 delivers the first discharge capacity of 107.6 mAh‧g −1 at 1 C. Importantly, the LiMg 0.02 Al 0.08 Mn 1.90 O 4 cathode achieves long cycling lifespans exceeding 1000 cycles at high current rates of 20 C. A capacity retention of 70.0 % is retained at 20 C after 1000 cycles, as well as a high-temperature capacity retention of 47.4 % after 500 cycles at 5 C and 55 °C. Moreover, the Mg 2+ /Al 3+ co-doping facilitates the kinetic process of Li + migration, leading to a relatively high Li + diffusion coefficient and a low apparent activation energy.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）