MOLECULES
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2022
·Vol. 27
·期 23
·8324
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IF 4.927
Xiuying Liu,Yuanyuan Cheng,Binbin Guan,Fei Xia,Ling Fan,Xue Gao,Xiaofei Sun,Xuepeng Li,Lijie Zhu
A multicolor immunochromatographic assay platform based on quantum dot nanobeads (QBs) for the rapid and simultaneous detection of nitrofuran metabolites in different aquatic products is documented. These metabolites include 3-amino-2-oxazolidinone (AOZ), 1-aminohydantoin (AHD), semicarbazide (SEM), and 3-amino-5-morpholino-methyl-1,3-oxazolidinone (AMOZ). QBs with emission colors of red, yellow, green, and orange were employed and functionalized with the corresponding antibodies to each analyte to develop a multicolor channel. The visual detection limits (cutoff values) of our method for AOZ, AHD, SEM, and AMOZ reached up to 50 ng/mL, which were 2, 20, 20, and 20 times lower than those of traditional colloidal gold test strips, respectively. The test strip is capable of detection within 10 min in real samples while still achieving good stability and specificity. These results demonstrate that the developed multicolor immunochromatographic assay platform is a promising technique for multiplex, highly sensitive, and on-site detection of nitrofuran metabolites.Keywords:nitrofuran metabolites;multiplex immunochromatographic assay;quantum dot nanobeads;fluorescent test strip
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Journal of Environmental Chemical Engineering
·
2022
·
IF 7.968
Yan Wu,Ling-Hui Kong,Rong-Fang Shen,Xiao-Jing Guo,Wen-Ting Ge,Wen-Jie Zhang,Zhen-Yue Dong,Xi Yan,Yan Chen,Wan-Zhong Lang
Herein, highly dispersed Fe species supported on activated carbon (CA-Fe-C) was fabricated with the aid of citric acid , showing excellent catalytic performance and stability for the degradation of rhodamine B (RhB) through peroxymonosulfate (PMS) activation. The radical quenching study, electron paramagnetic resonance (EPR) measurement and PMS consumption analysis confirmed the RhB degradation mechanism involving reactive radical species attacking RhB and non-radical oxidation pathway. The main degradation intermediates were identified by LC-MS, and the possible RhB degradation pathways were deduced. A multivariate quadratic polynomial model was developed using the response surface methodology (RSM) to examine how the removal of RhB was influenced by several quantifiable factors, with the objective of optimizing RhB removal. The analysis of variance (ANOVA) was used to evaluate the adequacy and significance of the proposed model. The effects of solution pH values, initial concentration, inorganic anions, PMS dosage, catalyst dosage, and metal loading amount on RhB removal were investigated. The method of initial rates was employed to determine the intrinsic reaction rate law, and the reaction was identified to follow the Langmuir-Hinshelwood (L-H) kinetics model.
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Journal of Materials Chemistry B
·
2022
·Vol. 10
·期 32
·6187-6193
·
IF 7.571
Lulan Yang,Xingyue Chen,Xu Wen,Jiaming Tang,Xiaoling Zheng,Jiaqi Li,Lingling Chen,Shuang Jiang,Tao Le
Sulfadiazine (SDZ) residues in food products and the environment pose a serious threat to human health and ecological balance, thereby warranting the development of new methods for simple, rapid and accurate detection of these compounds. To this end, we developed a novel label-free dual-modal aptasensor for SDZ detection based on distance-dependent color change of gold nanoparticles (AuNPs) and fluorescence resonance energy transfer between AuNPs and rhodamine B (RhoB). In this aptasensor, the binding of the aptamer to SDZ causes unprotected AuNPs to aggregate in NaCl solution, which alters the color of the solution and restores the fluorescence of RhoB. Under optimal conditions, the aptasensor exhibited a linear colorimetric response in the SDZ concentration range of 50–1000 ng mL−1, and a linear fluorescence response in the SDZ concentration range of 4–256 ng mL−1. The limits of detection for colorimetric and fluorescent readings were 28 ng mL−1 and 2 ng mL−1 respectively. The recoveries of SDZ in the spiked real samples were 88.28–108.44% by colorimetry and 90.27–106.04% by fluorometry. Furthermore, the results of this aptasensor showed excellent correlation (R2 ≥ 0.9858) with HPLC findings. Taken together, these experimental results demonstrate that the proposed label-free dual-modal aptasensor can be employed to screen for SDZ contamination in food and environmental samples.
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Materials Today Chemistry
·
2023
·
IF 7.3
L. Wang,D. Wang,Y. Tao,J. Wang,M. Tian,Q. Liu,Y. Yang,Y. Zou,F. Ke,X. Guo,X. Li,D. Gao
Phenylboronic acid functionalized high-crystallinity fluorescent covalent organic framework ( [email protected] ), which can be applied for rifamycin antibiotics and water sensing, and for rifamycin antibiotics adsorption, was synthesized for the first time. To effectively form [email protected] by post-synthetic modification, a fluorescent COF (COF–OMe) was prepared using deep-eutectic solvent as solvent without using catalyst. The [email protected] showed good fluorescence property and adsorption capacity, which owned superior effects in detecting and adsorbing rifampicin, rifapentine, and rifabutin. The results of fluorescence quenching mechanisms showed that internal filtration effect, dynamic quenching, and photoinduced electron transfer were the major mechanisms. Moreover, mainly due to the pore selectivity of [email protected] , hydrogen bonding, and π-π interaction, [email protected] showed good selectivity for three antibiotics. Finally, a dual-function platform based on [email protected] was successfully developed for sensing and adsorbing three antibiotics from various samples. Besides, [email protected] also showed good effect to detect water amount in ethanol (0.1−50%, v/v).
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MOLECULES
·
2023
·Vol. 28
·期 22
·7496
·
IF 4.6
Qian Han,Ling Fan,Xiuying Liu,Yiwei Tang,Pingping Wang,Zaixi Shu,Wei Zhang,Lijie Zhu
Quantum dot nanobeads (QBs) were used as signal source to develop competitive lateral flow immunoassay (LFIA) for the detection of chloramphenicol (CAP). The quantitative detection of CAP was achieved by calculating the total color difference (∆E) values of the test line (T line) using the images of test strips. QB-based LFIA (QBs-LFIA) allowed the effective dynamic linear detection of CAP in the range of 0.1–1.5 ng/mL. The limit of detection (LOD) was 3.0 ng/mL, which was 50 and 667 times lower than those achieved for two different brands of colloidal gold kits. The recoveries of CAP during real-sample detection were 82.82–104.91% at spiked levels of 0.1, 0.7, and 1.5 ng/mL. These results indicate that the developed QBs-LFIA facilitates the sensitive detection of CAP.
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FOOD CHEMISTRY
·
2023
·
IF 8.8
Lingjun Geng,Jiashuai Sun,Mengyue Liu,Jingcheng Huang,Jiwei Dong,Zhen Guo,Yemin Guo,Xia Sun
In this paper, an electrochemical sensor based on a dual recognition strategy of molecularly imprinted polymers (MIPs) and aptamer (Apt) has been designed for the high sensitivity detection of chloramphenicol (CAP). Here, MIPs and Apt have provided dual recognition sites to greatly improve the specific recognition ability of the sensor. Chitosan-multi-walled carbon nanotubes (CS-MWNTs) and AuNPs (gold nanoparticles) have been used for their excellent electrical conductivity. When CAP existed in the detection environment, the imprinted cavities with specific recognition ability bound to CAP through forces such as hydrogen bonds. It hindered the rate of electron transfer and resulted in a decrease in current value. Quantitative detection of CAP could be achieved after analyzing the relationship between the concentration of CAP and the change of current value. After optimizing the experimental parameters, the detection range of the sensor was 10 −8 g/L-10 −2 g/L with the limit of detection of 3.3 × 10 −9 g/L, indicating that the sensor had a high practical application potential.
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BIORESOURCE TECHNOLOGY
·
2023
·
IF 11.4
Yanzhuo Zhang,Yutai Sun,Rui He,Jing Zhao,Jiqin Wang,Tonghuan Yu,Xiaozhuan Zhang,Alexandr V. Bildyukevich
Simulation of microbial aging biochar in compost is an important index for evaluating the biochar degradation efficiency of antibiotics. In this study, biochar was prepared by adding microplastics (MPs) to sludge, and the degradation effect of biochar/(peroxymonosulfate, PMS) on antibiotics was evaluated during the compost aging process of biochar. After the compost aging of biochars, the antibiotic degradation efficiency of HPBC500, HPBC500 + polystyrene (PS), HPBC900/PMS, and HPBC900 + PS/PMS decreased by 6.47, 15.2, 10.16, and 10.33 %, respectively. Environmentally persistent free radicals (EPFRs) and defect structure were the main contributors to the activation of PMS. EPFRs produced through PS pyrolysis of biochar exhibited strong reactivity but poor stability during the degradation of antibiotics. Biochar enhanced the growth of microorganisms in compost but reduced its specific surface area. The antibiotic degradation efficiency of the biochar was positively correlated with the concentration of EPFRs. This study elucidated the durability of different biochar toward antibiotic degradation.
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ACS Applied Nano Materials
·
2023
·
IF 5.9
Xuan Wan,Haohao Du,Du Tuo,Xiaoman Qi,Tianyu Wang,Jingtao Wu,Guangli Li
The excessive use of gatifloxacin (GAT) can seriously pollute the environment and damage human health. Therefore, reliable detection of its concentration is essential for environmental protection and physical health. Herein, an efficient and stable voltammetric sensor based on zirconium-based metal–organic framework/carboxylated multiwalled nanotube nanocomposites (UiO-66/MWCNT-COOH) was constructed for the determination of GAT. The morphologies, microstructures, and electrochemical properties of UiO-66/MWCNT-COOH were investigated by using various microscopic, spectroscopic, and electrochemical techniques. UiO-66/MWCNT-COOH showed good electrocatalytic activity for GAT oxidation with remarkable voltammetric response signals, which was primarily attributed to the synergistic effect from UiO-66 and MWCNT-COOH. Electrochemical kinetics studies revealed that the electrocatalytic oxidation of GAT is an irreversible and diffusion-limited reaction involving two protons and two electrons. The anodic peak current of GAT is linearly correlated with GAT concentration in the range from 0.05 to 10 μM with a low detection limit of 0.0075 μM. Moreover, UiO-66/MWCNT-COOH demonstrated high selectivity, reproducibility, and repeatability as well as extraordinary long-term stability (at least 7 weeks). The proposed UiO-66/MWCNT-COOH reliably detected trace GAT in the effluent, milk, human serum, and eye drops with satisfactory recoveries. Together with its outstanding merits such as low cost, robust response, short assay time, and good sensitivity, the proposed sensor shows enormous prospects for in situ determination of multiple antibiotics.
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
·
2023
·Vol. 120
·期 43
·e2311585120
·
IF 11.1
Chao-Hai Gu,Song Wang,Ai-Yong Zhang,Chang Liu,Jun Jiang,Han-Qing Yu
Single-atom Fenton-like catalysis has attracted significant attention, yet the quest for controllable synthesis of single-atom catalysts (SACs) with modulation of electron configuration is driven by the current disadvantages of poor activity, low selectivity, narrow pH range, and ambiguous structure–performance relationship. Herein, we devised an innovative strategy, the slow-release synthesis, to fabricate superior Cu SACs by facilitating the dynamic equilibrium between metal precursor supply and anchoring site formation. In this strategy, the dynamics of anchoring site formation, metal precursor release, and their binding reaction kinetics were regulated. Bolstered by harmoniously aligned dynamics, the selective and specific monatomic binding reactions were ensured to refine controllable SACs synthesis with well-defined structure–reactivity relationship. A copious quantity of monatomic dispersed metal became deposited on the C3N4/montmorillonite (MMT) interface and surface with accessible exposure due to the convenient mass transfer within ordered MMT. The slow-release effect facilitated the generation of targeted high-quality sites by equilibrating the supply and demand of the metal precursor and anchoring site and improved the utilization ratio of metal precursors. An excellent Fenton-like reactivity for contaminant degradation was achieved by the Cu1/C3N4/MMT with diminished toxic Cu liberation. Also, the selective ·OH-mediated reaction mechanism was elucidated. Our findings provide a strategy for regulating the intractable anchoring events and optimizing the microenvironment of the monatomic metal center to synthesize superior SACs.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2023
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IF 4.4
Zhenping Liu,Jun Zhou,Xianfeng Wang,Jinsong Zhao,Peng Zhao,Yi Ma,Suyi Zhang,Danqun Huo,Changjun Hou,Kang Ren
In view of the urgent need for fluoroquinolones contamination detection in the fields of food safety, a novel aptasensor based on the fluorescence quenching property of graphene oxide (GO) and the fluorescence characteristic of cadmium selenide quantum dots (CdSe QDs) was developed for fluoroquinolones highly sensitive detection in this work. The CdSe QDs with carboxyl-rich surface were synthesized successfully and fluoresced at 525 nm under the optimal excitation light of 366 nm. Based on the hydrophobic and π-π stacking between GO and aptamer, aptamer labeled by CdSe QDs fluorescence (CdSe QDs-apt) were adsorbed by GO and the fluorescence of CdSe QDs was quenched. After the aptamer combined specifically with fluoroquinolones, greater specific force lead to the desorption of CdSe QDs-apt from GO and fluorescence recovery. Represented by Ciprofloxacin (CIP), a member of fluoroquinolones, the fluorescence emission increased with the increasing of CIP concentrations from 8 nM to 500 nM, and the detection limit was 0.42 nM. The spiked recoveries in real samples of honey and milk were 91.5–96.9 % and 90.3–95.2 %, respectively, indicating that the aptasensor was reliable. Moreover, the fluorescence responses of multiple members of fluoroquinolones were found to be consistent, denoting that the fluorescence aptasensor can be used to detect the total amount of multiple members of fluoroquinolones. These results showed that the aptasensor can be used as a promising platform for fluoroquinolones detection.
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JOURNAL OF HAZARDOUS MATERIALS
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2023
·
IF 13.6
Nan Li,Juan Zheng,Lu-Dan Yu,Yuan-Jun Tong,Xinying Gong,Yu Hou,Guosheng Chen,Jianqiao Xu,Fang Zhu,Gangfeng Ouyang
The complex sample matrix and low environmental concentration make it challenging to effectively determine the polar glucocorticoids. In particular, a green, economical, and environmentally friendly method is urgently needed, since a large amount of extraction solvents, samples, and extraction materials have been commonly used to improve the sensitivity of the reported methods. In this study, a green and robust phenol and bismuth-based MOF of SU101 was mildly synthesized and fabricated as a brand new solid-phase microextraction (SPME) fiber. Only tiny amounts of SU101 and desorption solvents were employed to realize the high-efficiency enrichments of glucocorticoids from water samples. The detection performance of proposed SU101 fiber towards glucocorticoids was much superior to the single-component and multi-component commercial fibers. It indicated that SU101 fiber could be an excellent candidate for the enrichments of polar pharmaceuticals. After it was coupled with the instrument of high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS), the linear range of 5–10000 ng L −1 with detection limits low to 0.070–1.5 ng L −1 and satisfactory recoveries were achieved by the developed method. Benefiting from the environmental friendliness of SU101 and the less-solvent consumption of SPME technique, this work presented a green and economical strategy for determinations of trace glucocorticoids.
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TALANTA
·
2023
·
IF 6.1
Baisen Chen,Rongxia Tan,Yanhui Zhong,Yufei Hu,Gongke Li
Ce-PA-Tb polymer with Ce and Tb as metal ion centers was prepared and applied in chemiluminescence (CL) reaction. The structure and property of Ce-PA-Tb were explored. Ce-PA-Tb combines both the oxidant ion (Ce(IV)) and luminescence ion (Tb(III)). Difloxacin can enhance the CL signal of Ce-PA-Tb-SO 3 2- reaction in acidic medium. Under the optimized affecting factors, a CL method for the selective difloxacin determination was established. The CL intensity showed a good linear relationship from 10.0 to 300.0 μg/L (r = 0.9996) with the limit of detection was 1.1 μg/L. The method with the signal response at 0.5 s and completed the CL process within 10 s. The method was used to determine difloxacin in aquatic products, and the recovery rate was in the range of 88.1%–104.0%. The CL method designed Ce-PA-Tb based is demonstrated to be an excellent tool for difloxacin determination in aquatic products.
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