Polymer Chemistry
·
2019
·Vol. 10
·期 33
·4537-4550
·
IF 4.76
Yu Yang,Haixun Ji,Haichao Duan,Yuqin Fu,Siwen Xia,Changli Lü
In this work, catechol-formaldehyde resin (CFR) microspheres were successfully prepared by a solvothermal method under alkaline conditions. Furthermore, the impacts of the concentration, solvent ratio and temperature on the size and morphology of the as-synthesized CFR microspheres were studied in detail. The results showed that the size of the CFR microspheres could be controlled between 50 and 800 nm by changing the reaction conditions, and the morphology of the CFR microspheres was significantly different under different conditions. The as-prepared CFR microsphere as a support was also used to construct a CFR-stabilized Ag nanoparticle (CFR@Ag) nanohybrid via an in situ reduction and growth process on mussel-inspired CFR layers. Upon alkaline solution treatment on the CFR microspheres, silver nanoparticles could be deposited onto the surface or inside of the CFR microspheres. Additionally, the abundant hydroxyl groups on the CFR spheres could act as reducing agents for both the Ag+ precursor and ligands to stabilize Ag NPs without additional reducing agents. The as-prepared CFR@Ag and alkali-treated CFR microsphere stabilized Ag NP (TCFR@Ag) nanohybrids could serve as highly efficient nanocatalysts for the reduction of 4-nitrophenol and methylene blue (MB) dye with good cycling stability. In addition, the nanohybrids as outstanding antibacterial agents also showed long-term inhibition of microbial growth against bacteria Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).
研究领域:
材料科学
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化学工程
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生物医学
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产品关联
DOI
高影响因子
International Journal of Nanomedicine
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2019
·
IF 4.471
Fengyi Du,Yunchao Wu,Fengting Du,Lirong Zhang,Weiwei Feng,Lulu Zhao,Rong Cai,Lixia Xu,Gaorui Bian,Jiangang Li,Shengqiang Zou,Aihua Gong,Miaomiao Zhang
Background: The gastroretentive drug delivery system is an effective administration route, which can improve the bioavailability of the drug and the therapeutic effect by prolonging the release time of the drug and controlling the release rate in the stomach.Methods: Inspired by the excellent adhesion properties of mussel protein, we prepared novel catechol-grafted chitosan alginate/barium sulfate microcapsules (Cat-CA/BS MCs) with mucoadhesive properties and computed tomography (CT) imaging function for gastric drug delivery. First, barium sulfate nanoclusters used as CT contrast agent were synthesized in situ in the Cat-CA/BS MCs through a one-step electronic spinning method. Next, catechol-grafted chitosan as the mucoadhesive moiety was coated on the surface of Cat-CA/BS MCs by polyelectrolyte molecule self-assembly.Results: The prepared Cat-CA/BS MCs could effectively retained in the stomach for 48 hours and successively released ranitidine hydrochloride, which could be used for the treatment of gastric ulcer. Cat-CA/BS MCs exhibited superior CT contrast imaging properties for real-time tracking in vivo after oral administration.Conclusion: These findings demonstrate that Cat-CA/BS MCs serving as multifunctional oral drug carriers possess huge potential in gastroretentive drug delivery and non-invasive visualization.
研究领域:
药剂学
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药物递送系统
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医学成像
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产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Xiaoxue Liu,Jiao Yang,Jing Cheng,Yi Xu,Wen Chen,Yingchun Li
Development of nanomaterials with multienzyme-like activities (nanozymes) via a simple way has attracted paramounting attention. Generally, enzymatic activity is closely related to the size, surface state, material type, etc. Bimetallic oxides are very appealing owing to their mixed valence and structural advantages. Herein, we reported an eco-friendly strategy to synthesize Co 1.5 Mn 1.5 O 4 nanozyme via sol-gel method. This nanozyme functionally mimics four major enzymes, i.e. laccase, peroxidase (POD), oxidase (OXD), and catalase (CAT). Accordingly, a colorimetric sensing platform was designed to distinguish isomers of organic pollutants ‒catechol (CC) and hydroquinone (HQ) by using Co 1.5 Mn 1.5 O 4 as the sole catalyst. In particular, laccase-like activity of Co 1.5 Mn 1.5 O 4 enables it to directly oxidize CC into yellow o -benzoquinone with good linearity in the range of 1∼1000 μM and a detection limit of 0.35 μM. Meanwhile, HQ can discolor the oxidized substrate that was pre-oxidized with the aid of oxidase-like activity of the nanozyme (linear range: 0.05∼100 μM, detection limit: 0.04 μM). The established colorimetric method has been successfully utilized for selective sensing of CC, HQ in water samples with good selectivity and high sensitivity. Our study contributes to green synthesis of metal-based nanomaterials with multi-enzyme mimicking activities and uncovers new usage of nanozyme in discriminating of environmental pollutants.
研究领域:
环境科学
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生物化学
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材料科学
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2012
·
IF 3.898
Longzhen Zheng,Leyan Xiong,Yindi Li,Jingpeng Xu,Xiaowei Kang,Zhijun Zou,Shaoming Yang,Jian Xia
A polydopamine (PDA)-reduced graphene oxide (RGO) nanocomposite was prepared by a one-step procedure and was characterized by Fourier transform infrared spectra (FTIR), electrochemical impedance spectra (EIS), and atomic force microscopy (AFM). The characterizations confirm the successful reduction of graphene oxide to RGO in the PDA-RGO nanocomposite. The application of PDA-RGO nanocomposite in simultaneous determination of hydroquinone (HQ) and catechol (CC) was investigated. The Δ E p between HQ and CC was 103 mV, which was wide enough to discriminate the dihydroxybenzene isomers. The peak current of HQ was linear to its concentration in the range of 1.0 × 10 −6 to 2.3 × 10 −4 M and the peak current of CC was linear to its concentration in the range of 1.0 × 10 −6 to 2.5 × 10 −4 M.
研究领域:
材料科学
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电化学分析
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产品关联
DOI
高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
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2022
·Vol. 169
·期 12
·127506
·
IF 4.386
Qi Wang,Jinjin Zhang,Wenjing Liu,Jianying Qu
Herein, the copper-based metal organic framework (CuBDC) modified with MoO3 nanorods uniformly distributed on its surface (MoO3@CuBDC) was synthesized by a one-step solvothermal method, and then was treated with high temperature calcination. A series of characterizations demonstrate that MoO3@CuBDC was transformed into a ternary composite of Cu2O nanospheres, Mo2C, and carbon material (Cu2O/Mo2C@C) after the treatment. Moreover, a novel electrochemical sensor based on Cu2O/Mo2C@C modified glassy carbon electrode (GCE) was constructed for simultaneous sensitive detection of catechol (CC) and hydroquinone (HQ). Due to the excellent electrocatalytic ability of Cu2O/Mo2C@C, the prepared sensor exhibits good electroanalytical performance, which shows good linearity in the concentration ranges of 0.50–200.00 μM for CC and HQ with the limits of detection of 0.38 μM and 0.13 μM. In addition, this sensor can be used to detect CC and HQ simultaneously in real samples with satisfactory results.
研究领域:
分析化学
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材料科学
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环境科学
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产品关联
DOI
高影响因子
Scientific Reports
·
2017
·Vol. 7
·期 1
·1-10
·
IF 4.259
Wang Zhong,Zhao Shujun,Song Ruyuan,Zhang Wei,Zhang Shifeng,Li Jianzhang
Novel soybean meal-based biomimetic (STP) adhesives were fabricated via soybean meal (SM) and enhanced by tannic acid (TA) and polyetheylenimine (PEI) (TAPI) co-crosslinking network based on natural polyphenol-inspired chemistry. The multiple physico-chemical interactions (including intermolecular H-bonding and covalent bonding) between the TAPI co-crosslinking system and SM matrices were examined by the Fourier transform infrared spectroscopy, solid-state 13 C nuclear magnetic resonance, X-ray diffraction, thermogravimetric analysis, and scanning electron microscopy. The results showed that a dense, robust, and water-resistant adhesive layer was constructed between network-bound catechol moieties in the TAPI and SM system, endowing the STP adhesive with high wet bonding strength for plywood. As expected, TAPI-modified SM adhesives showed a 156.1% increase in wet bonding strength compared to the control SM adhesive. The adhesion meets standard requirements for interior-use plywood. Both the solid content and residual mass analysis also confirmed that the enhancement in the STP adhesive was attributable to the network crosslinking density and stiffness after integrating the TAPI system. Moreover, the thermal stability of the resultant STP adhesive exhibited a significant improvement. The proposed STP adhesive may be a promising cost-effective and wet-resistant bio-adhesive for the application in the wood composites industry.
研究领域:
材料科学
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生物化学
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产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry B
·
2023
·Vol. 11
·期 23
·5123-5130
·
IF 7
Hong Wang,Mengmeng Gu,Menghua Yan,Xiuming Wu,Yuming Dong,Guang-Li Wang
Cathodic photoelectrochemistry, a research hotspot in state-of-art bioassays, is generally circumscribed by its monotonous signal transduction tactic of photoinduced electron transfer (PET) mechanism, which significantly narrows the scope of its applications. In this study, we reveal the surface oxygen vacancy (VO) formation elicited by the spontaneous coordination of catechol (CA) onto the surface of BiOI nanoplates for the innovative operation of the cathodic PEC signal transduction tactic. The in situ-generated VO functions as a carrier separation center to efficiently promote photocurrent generation. Taking tyrosinase (TYR) and Escherichia coli O157:H7 (E. coli O157:H7) as model targets, the established signal transduction tactic was validated as efficient and sensitive for the detection of the two targets with linear ranges from 1.0 × 10−4 to 1.0 U mL−1 and 5.0 to 1.0 × 106 CFU mL−1, respectively. Low-detection limits of 1.0 × 10−4 U mL−1 and 3.0 CFU mL−1 were achieved for TYR and E. coli O157:H7, respectively. This study opens up a new perspective of in situ generated surface VO on semiconductors, which underlies an innovative PEC signal transduction mechanism with convincing analytical performance. Hopefully, it might encourage more explorations of new methodologies for introducing surface vacancies with exquisite applications.
研究领域:
光电化学
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生物分析
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分析化学
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纳米材料
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生物传感器
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产品关联
DOI
PubMed
高影响因子
Advanced Healthcare Materials
·
2023
·
IF 10
Yiming Chen,Peng Ni,Renfeng Xu,Xueli Wang,Chunhui Fu,Kaixuan Wan,Yan Fang,Haiqing Liu,Yunxiang Weng
Wet adhesion is critical in cases of wound closure, but it is usually deterred by the hydration layer on tissues. Inspired by dopamine-mediated underwater adhesion in mussel foot proteins, wet tissue adhesives containing catechol with 2–3 carbons side chains are reported mostly. To make wet adhesion of this type of adhesives much tougher, catechol derivatives with a long aliphatic side chain (≈10 atoms length) are synthesized. Then, a series of strong wet tissue adhesive hydrogels are prepared through photoinduced copolymerization of acrylic acid with synthetic monomers. The adhesive hydrogel has a high cohesion strength, that is, tensile strength and strain, and toughness of ≈1800 kPa, ≈540%, and ≈4100 kJ m −3 , respectively. Its interfacial toughness on wet and underwater porcine skin is respectively ≈1300 and ≈1100 J m −2 , and its adhesion strength to wet porcine skin is ≈153 kPa. These values are much higher than those of dopamine-based adhesives in the same conditions, demonstrating that the long aliphatic side chain on catechol can greatly improve the wet tissue-adhesion. Additionally, the tough interfacial adhesion can be broken on demand with 5 wt.% aqueous urea solution. This adhesive hydrogel is highly promising in safe wound closure.
研究领域:
材料科学
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生物材料
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生物医学工程
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化学工程
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2019
·
IF 4.784
Wen Tang,Chao Chen,Wen Sun,Ping Wang,Dongzhi Wei
Owing to dopamine's excellent adhesion ability and easy modification, it has been widely applied for enzyme immobilization , while the high cost of dopamine and low activity recovery of immobilized enzyme highly impede large-scale application of immobilized enzyme . We herein developed a low-cost and ideal activity recovery enzyme immobilization strategy based on magnetic nanoparticles by replacing dopamine with cheap Catechol/tetraethylene pentamine (CPA) binary system and introducing spacer-arms. In brief, CPA was first polymerized and deposited on the surface of magnetic nanoparticles with a modified mussel-inspired method, and the generated poly(CPA) layer was further functionalized with ethylene glycol diglycidyl ether (EGDE) molecules as spacer-arms for enzyme immobilization. Subsequently, lipases as model enzymes were firmly immobilized on the surface of such amino-epoxy functionalized magnetic materials through ion exchange and covalent attachment with 180.6 mg/g support of loading capacity and 69.2% of activity recovery under the optimized conditions. Furthermore, the immobilized lipase exhibited the improved tolerance rang of pH, temperature and storage stability as well as excellent reusability. Most strikingly, the theoretical simulation and secondary structure analysis of immobilized lipase revealed that the biocompatible microenvironment and flexible tethering at interface could effectively improve performance of the immobilized enzyme and stability. Thus, this novel immobilized enzyme strategy will open up a new perspective for the development of enzyme immobilization and lower the cost of immobilized enzyme in large-scale industrial application.
研究领域:
材料科学
·
生物化学
·
生物技术
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纳米技术
·
酶学
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DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2016
·
IF 5.557
Sikuai Xue,Chengcai Li,Jiuming Li,Hailin Zhu,Yuhai Guo
To improve hydrophilicity and anti-fouling property of the polytetrafluoroethylene (PTFE) flat microfiltration (MF) membrane, a facile method was developed to modify the membrane via the co-deposition of catechol (CA) and polyethyleneimine (PEI) followed by surface mineralization of γ-(2,3-epoxypropoxy) propytrimethoxysilane (KH560). The surface chemical composition, surface morphology, hydrophilicity and filtration performance of the PTFE flat membrane were investigated by ATR-FTIR, XPS, FESEM, WCA and pure water flux measurements, respectively. After using this low-cost and simple modification method, the PTFE flat membrane was endowed with excellent hydrophilicity, high water permeation flux and superior anti-fouling property. Then, the oil/water separation tests were conducted using the modified PTFE flat membranes. The size distribution of the oil droplets is between 0.12–1.44 µm and the mean pore size of pristine PTFE flat MF membrane is 0.22 µm. The as-prepared hydrophilized PTFE flat membranes possess an excellent oil resistant ability with oil rejection ratio near 99%. Finally, the surface stability of the modified membrane was studied and the mineralized membrane showed excellent acid resistant ability. Therefore, this facile strategy holds attractive potential practical application in water environmental remediation.
研究领域:
材料科学
·
环境工程
·
膜技术
·
表面化学
·
水处理
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DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2013
·
IF 5.695
He-Fang Wang,Ye-Yu Wu,Xiu-Ping Yan
A room-temperature phosphorescence (RTP) strategy was developed for direct, additive-free discrimination of catechol from resorcinol and hydroquinone based on sodium tripolyphosphate capped Mn-doped ZnS quantum dots (STPP-Mn-ZnS QDs). The RTP response of STPP-Mn-ZnS QDs to the three isomers was pH-dependent, and the greatest difference in the RTP response to the isomers was observed at pH 8.0: catechol enhanced the RTP intensity of the QDs, while resorcinol and hydroquinone had little effect on the RTP intensity of the QDs. The enhanced RTP intensity of 1 μM catechol was not affected by the coexistence of 30 μM resorcinol and 50 μM hydroquinone at pH 8.0. The detection limit of this RTP method was 53 nM catechol, and the precision was 3.2% (relative standard deviation) for five replicate detections of 1 μM catechol. The discrimination mechanism was ascribed to the weak bonded ligand of STPP-Mn-ZnS QDs and the different interaction between the three isomers and STPP-Mn-ZnS QDs. The strong binding of catechol to Zn resulted in the extraction of Zn from the surface of STPP-Mn-ZnS QDs and the generation of holes that were trapped by Mn2+ to form Mn3+. Catechol also promoted the reduction of Mn3+ into Mn2+ excited state, thus ultimately inducing the enhanced RTP response of STPP-Mn-ZnS QDs.
研究领域:
分析化学
·
纳米材料
·
发光传感器
·
环境监测
·
化学传感
✓ 已验证
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2026
·
IF 3.9
Jintao Liu,Dekun Duan,Monan Wang,Jinghan Wang,Weixue Zhang,Yue Zhang,Qiuli Zhang,Gan Ye
Abstract Catechol-functionalized UiO-66(Zr) holds considerable promise for targeted catalytic transformations owing to its distinctive electronic and structural properties. However, the direct synthesis of such frameworks has remained a persistent synthetic challenge. Herein, we report a rational, solvent-free, one-pot synthetic strategy enabling precise control over catechol functionalization in UiO-66(Zr) (UiO-66(Zr)-(OH)2) with well-defined hierarchical porosity. The optimized UiO-66(Zr)-0.25(OH)2 displays markedly improved catalytic performance in the esterification of levulinic acid (LA) with primary alcohols to yield alkyl levulinates. This superior activity arises synergistically from three key features: (i) increased Brønsted acidity imparted by the ortho-dihydroxyphenyl groups; (ii) a hierarchical pore architecture that enhances mass transport and substrate accessibility; and (iii) strong adsorptive affinity for both LA and alcohol substrates. Under standardized 12 h batch reactions with an alcohol-to-LA molar ratio of 20 and 50 mg of catalyst, UiO-66(Zr)-0.25(OH)2 achieves LA conversions of 98.9, 97.9, 95.6, and 94.3% with methanol, ethanol, 1-propanol, and 1-butanol, respectively, while maintaining >99.9% selectivity for the corresponding products of alkyl levulinates at optimally tuned reaction temperatures (60, 70, 80, and 100 °C). This work establishes a practical and environmentally sustainable synthetic strategy for the rational design of functionalized metal–organic frameworks, enabling high-efficiency, heterogeneous catalysis in targeted reactions.
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DOI
高影响因子
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