ACS Applied Polymer Materials
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2025
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IF 4.7
Lingfeng Cui,Jing Qiao,Guanyue Zeng,Yuzhu Xiong,Gege Huang,Daiqiang Li
Developing biobased rubber composites that simultaneously boost tensile strength and elongation at break while integrating self-healing capacity and reprocessability remains a critical challenge in the rubber industry. Inspired by the unique multiple hydrogen bonding structure of spider silk and the dynamic β-hydroxy ester exchange reaction, this study constructed an epoxy polyurethane rubber containing octuple hydrogen bonds and incorporated it into epoxidized natural rubber. Carboxylated silica was utilized as a bridging agent to form β-hydroxy ester reversible covalent bonds at the interface between the filler and the rubber, thereby designing a high-strength, self-repairing, and reprocessable’vitrimer’ biobased elastomer. This design approach endows the material with outstanding mechanical properties (tensile strength of 8.92 MPa, Young’s modulus of 2.71 MPa, toughness of 17.45 MJ/m3), excellent self-healing performance (healing efficiency of 92.1%), and superior processability (tensile strength recovery of 97.6%). These properties are primarily attributed to the presence of reversible noncovalent octet hydrogen bonds and dynamic covalent β-hydroxy ester bonds. Furthermore, this design can be readily implemented across different biobased epoxy polymers and carboxyl-rich nanofillers. The design concepts presented herein can be applied to the development of self-healing and reprocessable’vitrimer’ biobased elastomers, providing valuable insights for the future design of green and sustainable polymers.
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ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
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2025
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IF 2.9
Liu Zaizhi,Liao Haibin,Li Hualan,Zou Zhengrong
Cinnamomum camphora chvar. Borneol essential oil (CBEO), a potential antibacterial ingredient, faces challenges in widespread use for food preservation due to its high volatility and low stability. This study aimed to enhance the stability and release properties of CBEO by preparing CBEO/β-cyclodextrin microcapsules. The ultrasound-assisted complexation (UACP) method has been developed to fabricate microcapsules containing CBEO , with β -cyclodextrin used as the wall material. The UACP process was optimized using the Box–Behnken response surface methodology. Under optimal conditions—a wall–core ratio of 4.09, ultrasound time of 52 min, ultrasound power of 617 W, and embedding temperature of 32 °C—the maximum microcapsule yield (84.93 ± 2.21%) and encapsulation efficiency (60.20 ± 1.56%) were achieved. Analysis through scanning electron microscopy, Fourier transform infrared spectroscopy, particle size distribution analysis, thermogravimetric analysis, and X-ray diffraction revealed the effective encapsulation of CBEO by UACP method. Furthermore, CBEO microcapsules exhibited favorable thermal stability and a slow-release effect. This study presents a promising approach to microencapsulation technology for the preparation of plant essential oil microcapsules.
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RENEWABLE ENERGY
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2025
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IF 9.1
Yingfu Tian,Tianliang Lu,Hongjin Qu,Xiaomei Yang,Lipeng Zhou
Efficient conversion of ethyl levulinate (EL) in high concentration to γ-valerolactone (GVL) at moderate temperature via catalytic transfer hydrogenation strategy is highly desirable. In this work, hydrothermally synthesized Sn-β zeolite with high Sn content was employed as a catalyst to realize this aim. Fully crystallized Sn-β zeolite with high Sn content ( n Si / n Sn = 60) was successfully synthesized within 12 days using MgCl 2 as a promoter. The synthesized zeolites were characterized by XRD, SEM, UV-vis spectroscopy, FT-IR spectroscopy and XPS. The L acid density of Mg-Sn-β-60-12d increased to 90 μmol g −1 compared to Mg-Sn-β-100-7d (56 μmol g −1 ). 92% yield of GVL was achieved on Mg-Sn-β-60-12d using high concentration of EL (1.2 mol L –1 ) as reactant at 130 o C for 8 h. The performance of Mg-Sn-β is better than that of Sn-β with same n Si / n Sn . The reaction mechanism over Mg-Sn-β was discussed. In addition, Mg-Sn-β-60-12d showed excellent stability and reusability during five runs.
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MEDICAL ENGINEERING & PHYSICS
·
2025
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IF 2.3
SHENGJIE WANG,WEI LIU,CHAO YANG,XIANLONG ZHANG,CHUNMING LYU
Prosthetic loosening represents a catastrophic postoperative complication in artificial joint replacement, resulting in severe patient morbidity and substantial healthcare costs. This investigation aimed to develop a novel strategy for preventing prosthetic loosening. Two-dimensional MXene V 2 C nanosheets were synthesized and subsequently immobilized onto three-dimensional porous sulfonated polyetheretherketone (SPEEK) surfaces with polydopamine (PDA) to form V 2 C-PDA@SPEEK (Abbrev. V 2 C-PS). The biocompatibility was systematically evaluated using rat bone marrow mesenchymal stem cells (rBMSCs) and murine models. The osteogenic differentiation potential of V 2 C-PS was assessed through real-time PCR analysis, Alkaline phosphatase (ALP) staining, and Alizarin Red staining. The in vivo osteogenic capacity of V 2 C-PS surrounding the implant material was evaluated in rat femoral models using micro-CT analysis, biomechanical pull-out testing, sequential fluorescent labeling of newly formed bone, and Van Gieson staining. The molecular mechanisms underlying V 2 C-PS -mediated osteogenic differentiation of rBMSCs were investigated both in vitro and in vivo using chemical inhibitors, β-catenin shRNA lentiviral silencing, and β-catenin mRNA lentiviral overexpression. The results demonstrated that V 2 C-PS exhibited excellent biocompatibility. Quantitative analysis revealed substantial upregulation (p<0.05) of critical osteogenic markers, including RUNX2 (4.4-fold), COL-1 (5.7-fold), OCN (3.3-fold), BMP-2 (4.4-fold), OPN (3.1-fold), BSP (3.3-fold), ON (4.3-fold), and OSX (2.83-fold), in the 25V 2 C-PS treatment group compared to PS group. The bone parameters were also remarkably enhanced in the 25V 2 C-PS group (BMD increased by 241 %, bone-implant contact by 159 %, BV/TV by 225 %, Tb.N by 281 %, Tb.Th by 214 %, maximum pull-out force by 250 %, and Tp.Sp decreased by 33 %). Furthermore, V 2 C-PS were found to enhance rBMSC osteogenic differentiation through activation of the Wnt/β-catenin signaling pathway. This study presents a promising approach for preventing orthopedic prosthetic loosening and demonstrates significant potential for clinical translation.
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MACROMOLECULES
·
2025
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IF 5.2
Ziyuan Zhou,Binghua Wang,Changyu Shen,Bin Zhang
Previous research studies on isotactic polypropylene (iPP) have shown that the ratio of growth rate β to α phase (Gβ/Gα) exceeds 1 when the crystallization temperature (Tc) is between the lower and upper critical temperature limits (Tc** ∼ 100 °C and Tc* ∼ 141 °C, respectively), due to the faster surface kinetics of β-iPP. However, in this work, we observed that when the film thickness (d) decreases from 24 to 9 nm, the temperature interval of Gβ/Gα > 1 narrows and even disappears, as Tc* gradually shifts to lower temperatures while Tc** remains constant. This is presumably because, as d decreases, the width (wd) of the depletion zone of β-iPP expands more significantly than that of α-iPP, resulting in slower diffusion toward the growth front of β-iPP. Consequently, Gβ decreases more than Gα as d diminishes, leading to a reduction in the value of Gβ/Gα, especially at higher Tc, where Gβ/Gα becomes less than 1. Moreover, we found that the diffusion activation energy (Eaβ) of β-iPP is consistently greater than that of α-iPP (Eaα) at a given d, and the gap between Eaα and Eaβ increases as d decreases. This further highlights that the slower diffusion process for β-iPP progressively becomes the main factor affecting the difference between Gα and Gβ as d diminishes.
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高影响因子
MOLECULES
·
2023
·Vol. 28
·期 18
·6713
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IF 4.6
Cong Huang,Yuan Zhong,Rong Zeng,Jie Wang,Qingwen Fang,Shuzhen Xiao,Ji Zhang,Zongde Wang,Shangxing Chen,Dayong Peng
In order to develop a new type of antioxidants with high efficiency, a series of β-ionone thiazolylhydrazone derivatives were designed and synthesized from β-ionone, and their structures were characterized by1H-NMR,13C-NMR, FT-IR, and HR-MS. The antioxidant test in vitro indicated that most of the target compounds had high biological activity. Among them, compound1kexhibited very strong DPPH (1,1-diphenyl-2-picrylhydrazyl radical)-scavenging activity with a half-maximal effective concentration (IC50) of 86.525 μM. Furthermore, in the ABTS (2,2-azinobis (3-ethylbenzothiazoline-6-sulfonate) diammonium salt)-scavenging experiment, compound1mexhibited excellent activity with an IC50of 65.408 μM. Their biological activities were significantly better than those of the positive control Trolox. These two compounds, which have good free-radical-scavenging activity in vitro, were used as representative compounds in the anti-browning experiment of fresh-cut potatoes. The results showed that1kand1mhad the same anti-browning ability as kojic acid, and they were effective browning inhibitors. In addition, it is well known that microbial infection is one of the reasons for food oxidation. Therefore, we investigated the antifungal activity of 25 target compounds against eight plant fungi at a concentration of 125 mg/L. The results indicated that these compounds all have some antifungal activity and may become new potential fungicides. Notably, compound 1u showed the best inhibitory effect againstPoria vaporaria, with an inhibition rate as high as 77.71%; it is expected to become the dominant structure for the development of new antifungal agents.Keywords:thiazolylhydrazone;synthesis;antioxidant;antifungal;anti-browning
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JOURNAL OF MOLECULAR LIQUIDS
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2023
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IF 6
Nan Zhou,Hua Yan,Peibai Wei,Hongyu Guo,Fafu Yang
Although some AIE-based CPL materials had been presented, the design and synthesis novel AIE-based CPL materials and studies on the relationship of structure–property were still a challenging work. Herein, series of novel 1,4-bis(β-cyanostyryl)benzene derivatives 2a , 2b and 2c bearing chiral alkyl chains were prepared, and the influence of length of alkyl chains on CPL properties were investigated for the first time. Samples 2a , 2b and 2c were synthesized by simple procedure with 83–88 % yields. Samples 2b and 2c with longer chains displayed the typical liquid crystalline properties. All of them showed strong fluorescence in both solution and aggregated states. Their chiroptical properties of CD and CPL signals were influenced strongly by the molecular stacking in various states. The self-assembly in mesophase resulted in the best chiroptical properties. The longer alkyl chains contributed to stronger CD and CPL signals. The highest g lum value attained 1.6 × 10 -2 for sample 2c based on the effective chirality transfer and amplification of liquid-crystalline mesophase.
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JOURNAL OF HAZARDOUS MATERIALS
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2020
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IF 9.038
Yuancai Lv,Jiachen Ma,Kaiyang Liu,Yanting Jiang,Guifang Yang,Yifan Liu,Chunxiang Lin,Xiaoxia Ye,Yongqian Shi,Minghua Liu,Lihui Chen
A porous β -cyclodextrin modified cellulose nano-fiber membrane (CA-P-CDP) was fabricated and employed to treat the trace bisphenol pollutants (bisphenol A (BPA), bisphenol S (BPS), and bisphenol F (BPF)) in water. The characterization highlighted the porous structure, stable crystal structure, good thermal stability of the obtained CA-P-CDP, as well as abundant functional groups, which could greatly improve the adsorption of bisphenol pollutants and recovery. During the static adsorption process, the adsorbents dosage, temperature and pH showed significant influence on the adsorption performance. At the selected conditions (25 °C, 7.0 of pH and 0.1 g L -1 of CA-P-CDP dosage), the BPA/BPS/BPF adsorption on CA-P-CDP could rapidly reached the equilibrium in 15 min by following the pseudo-second-order kinetic model, and the maximum adsorption capacities were 50.37, 48.52 and 47.25 mg g −1 , respectively, according to Liu isotherm model. The mechanisms between the bisphenol pollutants and CA-P-CDP mainly involved the synergism of hydrophobic effects, hydrogen-bonding interactions and π-π stacking interactions. Besides, the dynamic adsorption data showed that the volume of treated water for CA-P-CDP (0.58 L) was 14.5 times larger than that of pristine cellulose membrane (0.04 L), revealing satisfactory adsorption performance of trace BPA in water. Furthermore, during the treatment of real water samples (lake water and river water) with trace bisphenol pollutants, the complete removal of the pollutants were evidently observed, which strongly verified the possibility of CA-P-CDP for the practical application.
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TEXTILE RESEARCH JOURNAL
·
2017
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IF 1.443
Ruijun Wang,Zhengchu Liu,Lifeng Cheng,Shengwen Duan,Xiangyuan Feng,Ke Zheng,Yi Cheng,Jie Zeng
Xylanase plays an important role in the hydrolysis of hemicellulose and has gained much attention in the field of biological degumming. The research for xylanases with cellulase-free and high activity for biological degumming has intensified in recent years. In the present research, heterologous expression of a novel endo-β-1,4-xylanase (GH30) from Dickeya dadantii DCE-01 in Escherichia coli BL21 (DE3) was reported. Biochemical characterization of the enzyme and a potential application in ramie biological degumming was discussed. The results showed that the xylanase gene consists of 1251 nucleotides, belonging to glycoside hydrolase family 30 (GH30). The optimal activity of the xylanase was observed at 50℃ and a pH value of 6.4. The Km and Vmax values for beechwood xylan were 14.25 mg/mL and 296.6 μmol/mg, respectively. The catalytic activity was enhanced by addition of 1 mM Cu2+, Ca2+, Mg2+, and K+. The recombinant enzyme was specific for xylan substrates. The enzyme exhibited hydrolytic activity toward ramie hemicellulose. The recombinant xylanase could be effectively applied to ramie degumming.
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EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
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2022
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IF 7.088
Li-An Shen,Xinyan Peng,Ya Bao,Chenglong Liu,Hao Zhang,Jianqi Li,Di Zhu,Qingwei Zhang
The β -catenin/B-cell lymphoma 9 (BCL9) protein-protein interaction (PPI) is a potential target for the suppression of hyperactive Wnt/ β -catenin signaling that is vigorously involved in cancer initiation and development. Herein, we first described quercetin and its derivatives had potential inhibitory effects on β -catenin/BCL9 PPI. The most potent compound, quercetin-3′- O -(4-methylpiperazine-1-yl) propyl ( C1 ), directly binded with β -catenin and disrupted the β -catenin/BCL9 interaction in both the protein level and the cellular context. C1 also effectively inhibited colorectal cancer in vitro and showed better selectivity in inhibiting hyperactive Wnt/ β -catenin signaling cells like CT26 and HCT116. And we further confirmed that C1 could inhibit CT26 tumor growth in vivo and regulate the tumor immune microenvironment. This study provides a good chemical probe to explore β-catenin-related biology and a drug-like quercetin derivative as novel β -catenin/BCL9 PPI inhibitors for further drug development.
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FOOD CHEMISTRY
·
2025
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IF 9.8
Yanyan Wu,Yamei Wu,Yongqiang Zhao,Huan Xiang,Zhiming Hao,Qing Wang,Yueqi Wang
The effect of oat β-glucan (OG) on the structure, interfacial behavior and emulsion rheological properties of sea bass myofibrillar protein (MP) was investigated. Fourier transform infrared spectroscopy demonstrated that adding OG decreased the α-helix content in MP from 27% to 22% and increased the β-sheet content, suggesting that OG facilitated MP unfolding. When the OG content was 1.2%, the interfacial tension decreased by approximately 20%, and the diffusion rate increased by approximately 1.5-fold. These changes augmented the physical stability of emulsions. Rheological analysis showed that 3% OG promoted the energy storage modulus (G') of the emulsion. These changes enhanced MP adsorption and rearrangement at the oil-water interface, which enhanced viscoelasticity in the interfacial film and further increased the emulsion stability. These findings augment the understanding of protein-polysaccharide interactions and provide guidance for improving protein emulsion stability.
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GREEN CHEMISTRY
·
2025
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IF 9.2
Keyi Huang,Chengqi Zhao,Zixuan Xu,Qing Zhao,Huiqin Xu,Xiaomin Zhang,leizhi zheng,You-Ting Wu
The efficient capture and conversion of hydrogen sulfide (H2S) represent a critical challenge in addressing key issues in energy and environmental fields. In this study, we innovatively designed and synthesized a series of carbonyl-functionalized metallic ionic liquids (CMILs), which exhibit dual functionality as both absorbents and catalysts under mild conditions. Experimental results demonstrate that the [Na-15C][LA] system delivers outstanding performance under ambient conditions (30 ℃, 1.0 bar), achieving an H 2 S absorption capacity of 1.73 mol/mol, H 2 S/CO 2 selectivity of 101.2, and an exceptionally high H 2 S/CH 4 selectivity of 1122.2. NMR, FT-IR, and DFT calculations confirm that the carbonyl group serves as the active site for efficient H 2 S capture.Notably, these CMILs function as highly effective catalysts, facilitating the solvent-free conversion 2 of H 2 S with α, β-unsaturated carboxylates into thiols and thioethers under mild conditions. Moreover, the system enables spontaneous phase separation between the catalyst and products without requiring additional components, achieving quantitative conversion (> 99%) while adhering to green chemistry principles. This integrated design provides a novel technical approach for the efficient capture and resource utilization of H2S.
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