JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2019
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IF 3.571
Ning Yan,Xiao-Fang Wan,Xin-Sheng Chai
This study reported a new headspace gas chromatography (HS-GC) for simultaneously determining the degree of deacetylation (DD) and the degree of substitution (DS) in carboxymethyl chitosan (CMCS), which were based on HS-GC measuring the amounts of CO2 released from both the bicarbonate decomposition suppressed by -NH2 and the reaction between the bicarbonate and the acidified carboxymethyl and amino groups in CMCS. The results showed that the present method has a good measurement precision (RSD < 2.55%) and accuracy (relative differences <5.90%). Compared with the current titration-based method, the present HS-GC techniques provide a more reliable testing in the quantification of amino and carboxymethyl contents in CMCS. Moreover, since the HS-GC can perform an automated sample reaction equilibration and measurement, it could be much more efficient than the existing methods in the batch sample analysis.
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Separations
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2025
·Vol. 12
·期 8
·193
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IF 2.7
Jiaonan Cai,Yong Bai,Fang Li
Interfacial solar evaporation has emerged as a promising strategy for freshwater production, where 3D evaporators offer distinct advantages in heat management and salt rejection. Freeze–thaw cycling is a widely adopted fabrication method for 3D hydrogel evaporators, yet the impact of preparation conditions (e.g., freezing temperature) on their evaporation performance remains poorly understood, hindering rational optimization of fabrication protocols. Herein, we report the fabrication of chitosan-based hydrogel evaporators via freeze–thaw cycles at different freezing temperatures (−20 °C, −40 °C, and −80 °C), leveraging its low cost and environmental friendliness. Characterizations of crosslinking density and microstructure reveal a direct correlation between freezing temperature and network porosity, which significantly influences evaporation rate, photothermal conversion efficiency, and anti-salt performance. It is noteworthy that the chitosan hydrogel prepared at −80 °C demonstrates an excellent evaporation rate in high-salinity environments and exhibits superior salt resistance during continuous evaporation testing. Long-term cyclic experiments indicate that there was an average evaporation rate of 3.76 kg m−2h−1over 10 cycles, with only a 2.5% decrease observed in the 10th cycle. This work not only elucidates the structure–property relationship of freeze–thaw fabricated hydrogels but also provides a strategic guideline for tailoring evaporator architectures to different salinity conditions, bridging the gap between material design and practical seawater desalination.
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JOURNAL OF APPLIED POLYMER SCIENCE
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2025
·
IF 2.8
Linfeng Hu,Yunlong Wang,Hongying Niu,Hongxia Zhu
This study developed chitosan-based hydrogels as field-deployable carriers for sustained fungicide delivery to enhance crop disease resistance and yield. Citral and chitosan were reacted at three molar ratios (N1, N1.5, N2) via acid-catalyzed Schiff-base condensation, and the resulting hydrogels were characterized by FTIR, 1 H NMR, SEM and WXRD. Structural analyses confirmed the formation of self-ordered imine clusters with a d -spacing of 20.5 Å stabilized by non-covalent interactions. N1, the highest-cross-linked hydrogel, showed the best thermal stability ( T 10 = 160°C) and the lowest swelling, releasing 7.0% slower than N1.5 and 37.9% slower than N2. Antifungal assays demonstrated that N1 provided the strongest inhibition against five phytopathogens ( Rhizoctonia solani , Fusarium graminearum , Botrytis cinerea , Rhizoctonia cerealis , and Phytophthora capsici ), improving inhibition of B. cinerea , P. capsici , and F. graminearum by 56.8%, 82.9%, and 181.3%, respectively, compared with free citral. These hydrogels combine antifungal activity, water retention, thermal stability and controlled release, providing a promising strategy for green fungicide delivery in agriculture.
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JOURNAL OF HAZARDOUS MATERIALS
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2019
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IF 7.65
Chaofan Zheng,Huaili Zheng,Yongjuan Wang,Yongjun Sun,Yanyan An,Hongxia Liu,Shuang Liu
In this study, modified magnetic chitosan microparticles (MCDs) were fabricated and used as adsorbents for the removal of Food Yellow 3 (FY3) and Acid Yellow 23 (AY23) from aqueous solution. The magnetic microparticles were characterized by scanning electronic microscope, Brunauer-Emmett-Teller specific surface area, elemental analysis, Fourier transform infrared spectroscopy , X-ray photoelectron spectroscopy, thermogravimetry analysis, differential scanning calorimetry , and vibrating-sample magnetometer. Then, the effects of pH value, initial dye concentration, and contact time on the adsorption of FY3 and AY23 by MCDs were investigated. Evidently, MCDs showed excellent adsorption performance for both food dyes, and their adsorption capacities (833.33 mg/g for FY3 and 666.67 mg/g for AY23) were considerably higher than those of unmodified adsorbents, which could be attributed to the electrostatic interaction and ion exchange between the grafted cationic polymer and food dyes. Adsorption isotherm and kinetic data of the magnetic microparticles were well fitted by Langmuir isotherm and pseudo-second-order kinetic model, respectively. The regeneration and reusability of MCDs were also explored. Results showed that more than 80% adsorption capacities of MCDs for FY3 and AY23 remained after five adsorption-desorption cycles.
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CARBOHYDRATE POLYMERS
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2020
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IF 7.182
Jin Wang,Lehao Zhou,Qihao Sun,Haibo Cai,Wen-Song Tan
The proliferation and osteogenic differentiation of mesenchymal stem cells (MSCs) needed to be promoted for their use in stem cell-based therapy for large bone defects. This study aimed to prepare porous 2a-2 g scaffolds with antioxidant activity to reduce intracellular reactive oxygen species (ROS), which resulted in promoting the proliferation and osteogenic differentiation of MSCs. A series of novel chemically modified 2a-2 g scaffolds were fabricated by an acid-soluble/alkali-insoluble method. Besides, these 2a-2 g scaffolds had good biocompatibility, physicochemical properties and the ability to promote osteogenic differentiation of human adipose-derived stem cells ( h ADSCs). However, the proliferation ability of h ADSCs on 2a-2f scaffolds was weakened. Interestingly, 2 g scaffold had a positive effect on h ADSCs proliferation. These results indicated that the reduction of intracellular ROS was not conducive to h ADSCs proliferation but beneficial to h ADSCs osteogenic differentiation. Taken together, these significant results highlighted potential therapeutic benefit of 2 g scaffold in large bone defects.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Yu Ma,Dongyu You,Yu Fang,Jian Luo,Qinhe Pan,Yunling Liu,Fei Wang,Weiting Yang
The removal of lead ions from water is a global concern due to the great damage to human health when they enter the human body through drinking water. Herein, metal-organic framework/chitosan composite beads for the adsorption of Pb(II) were prepared by the secondary growth method, which allowed the domain-limited growth of TIF-A1 (a tetrahedral imidazolate framework) in the porous matrix of chitosan. This material can remove trace Pb(II) from aqueous solution (100 ppb) with an efficiency of 99.95%, and the remaining Pb(II) content meets the international drinking water standards. Moreover, it exhibited good recoverability for at least five adsorption/desorption cycles. The adsorption mechanism can be ascribed to that Pb(II) ions chelate with the hydroxyl, carboxyl and amino groups in the adsorbent. This work offers a good adsorbent for the removal of trace Pb(II), which has potential applications in reclaimed water treatment.
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CARBOHYDRATE POLYMERS
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2024
·
IF 10.7
Tiantian Wang,Bingbing Xu,Tong Yu,Yan Yu,Jiayi Fu,Yuhang Wang,Xianwu Gao,Zhebin Xue,Ruoxin Li,Guangtao Chang
Hydrogels have garnered significant interest as promising materials for flexible wearable devices. However, it remains a major challenge to develop multifunctional hydrogels. In this study, we prepared a multifunctional hydrogel based on the polyvinyl alcohol (PVA) and chitosan (CS), which is characterized by high strength, good electrical conductivity, and resistance to freezing and water retention. The hydrogel formulation utilizes p -carboxyphenylboronic acid (PBA) and MXene in combination with freeze-thaw cycling and glycerin (GL) immersion technology. Additionally, we explored the applications of this hydrogel in motion detection and sensing. Research results indicate that the hydrogel has excellent mechanical properties, achieving a strength of up to 3.42 MPa, with modulus and toughness improved by 7 times and 5 times, respectively, compared to pure PVA hydrogels. Moreover, when the MXene dispersion is at 8 vol%, the conductivity is 163.15 mS/m, and we explore their applications in strain sensing (GF = 7.03) and motion detection. The hydrogels exhibit a good strain range (600 %) and a fast response time (42 ms), as well as regular and stable electrical signals demonstrated at joints and breathing, providing strategic support for the application of this hydrogel in the field of smart wearable flexibility.
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Polymer Chemistry
·
2024
·
IF 4.1
Ningning Zhang,Xianjie Pan,Aoqian Xi,Wenpei Chen,Ting Huang,Yanning Zeng
The increase in nondegradable polymer waste and the depletion of nonrenewable fossil resources result in environmental concerns and unsustainable industrial development. It is significant to fabricate polymer thermosets with degradable, self-healable, weldable and recyclable performances from biomass. Herein, for the first time, natural peach gum (PG) as an attractive feedstock was employed to prepare degraded and recycled polyimine (PI) networks, due to the hydrolysable and renewable nature of PG. Firstly a peach gum polysaccharide with pendent –CHO groups (PGP-CHO) was synthesized through a graft reaction between 4-formylbenzoic acid and PGP; then it was cured with chitosan (CS) via a moderate and catalyst-free Schiff base reaction resulting in fully biobased PI networks (PGCS). The resultant PGCS-100 networks display good mechanical properties (tensile strength of ∼56.5 MPa and Young's modulus of ∼439 MPa) and high thermal stability (initial decomposition temperature around 227.1 °C). Meanwhile, the PGCS-100 network containing the most dynamic imine bonds exhibits superior self-healing, welding, shape memory and reprocessing performances. Moreover, PGCS-100 can be degraded completely under acidic conditions, allowing sustainable recycling. Furthermore, PGCS-100 can be applied in recycled adhesion, exhibiting excellent adhesion strength (10.5 MPa). Briefly, a new strategy to develop green environmentally friendly PI networks with high performance from biomass is provided, contributing to the reduction of polymer waste and sustainable industrial development.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Yilin Yu,Ning Kong,Zhaoyang Hou,Libo Men,Pei Yang,Zhengjin Wang
Developing a packaging material with integrated cushioning, intelligent and active functions is highly desired but remains challenging in the food industry. Here we show that a sponge-like porous hydrogel with pH-indicating and antibacterial additives can meet this requirement. We use polyvinyl alcohol and chitosan as the primary polymers to construct a hydrogel with hierarchical structures through a freeze-casting method in combination with salting-out treatment. The synergy of aggregated polymer chains and the sponge-like porous structure makes the hydrogel resilient and efficient in energy absorption. It also enables rapid movement of molecules/particles and fast reaction due to the large specific surface area of the pore structures and the large amount of free water in it, leading to a sensitive pH-indicating function. The hydrogel shows an obvious color variation within a wide pH range in 3 min. The silver nanoparticles are fixed in the dense polymer networks , enabling a lasting release of silver ions . The porous structure makes the silver ion reach the protected item in a short time, achieving an antibacterial effect against S. aureus and E. coli with little cytotoxicity. This work paves the way for fabricating multifunctional hydrogels for diverse advanced packaging systems.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yong Zhang,Zhengyang Xue,Xuan Liu,Jiaqi Feng,Kexing Jiang,Yujia Liu
With the development of the nuclear industry, the direct discharge of uranium-containing wastewater has become increasingly harmful to the environment. A novel graphene oxide-supported and phosphoric-crosslinked chitosan gel bead (C-PGCB) with excellent uranium uptake capability was successfully fabricated to treat uranium-containing wastewater. The experimental results showed that the introduction of P O and C O bonds through phosphoric acid crosslinking could greatly improve the capturing ability of chitosan-based materials, which could reach 97.1 % and 460.9 mg g −1 within 20 min, respectively. In the presence of multiple coexisting ions, the adsorbent still maintained high uranium adsorption efficiency. After 5 cycles, the uptake efficiency of C-PGCB with good cycle stability remained above 90 %. The fitting both the dynamic model and the isotherm model showed that the uranium uptake of C-PGCB was a uniform single-layer chemisorption process. Furthermore, the excellent dynamic separation properties proved the great potential value in the uranium-containing wastewater treatment. The uptake of C-PGCB for uranium could be owed to synergistic complexation and electrostatic interaction between uranium and multifunctional groups on C-PGCB. This work offered a chitosan-based adsorbent to effectively remove uranium from wastewater and gave a novel and effective way for the construction of chitosan-based adsorbents to enhance capture performance.
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AAPS PHARMSCITECH
·
2025
·Vol. 26
·期 4
·1-17
·
IF 4
Luo Zhilin,Sun Yao,Cai Shihao,Liu Hongting,Zhao Conglu,Xu Xiang,Xu Aiguo,Zhou Honggang,Yang Cheng,Gu Xiaoting,Ai Xiaoyu
Idiopathic Pulmonary Fibrosis (IPF) is a rare and serious chronic interstitial lung disease that may endanger the lives of patients. The median survival time of patients with idiopathic pulmonary fibrosis is short, and the mortality rate is higher than that of many types of cancer. At present, pirfenidone (PFD) and nintedanib (NDNB) have been approved by FDA for IPF, but they can only delay the process of pulmonary fibrosis and cannot cure the disease. Therefore, it is urgent to develop other drugs with the effect of improving pulmonary fibrosis. Ellagic acid (EA) can inhibit the Wnt-signaling pathway and has an effect in treating pulmonary fibrosis induced by bleomycin (BLM) in mice. However, its solubility is poor, resulting in its low bioavailability and limited therapeutic benefits, so its clinical application has been limited. Herein, based on the characteristics of nano-drug lung delivery system, chitosan (CS) was selected as the carrier, and ellagic acid-loaded chitosan nanoparticles (EA-CS-NPs) were prepared by ionic gelation method. The EE% and DL% of prepared EA-CS-NPs was 73.73 ± 4.52% and 6.23 ± 1.09%, the particle size was 119.6 ± 5.51 nm (PDI = 0.234 ± 0.017), the zeta potential was 29.833 ± 0.503 mV. The morphology of the nanoparticles was observed by TEM microscope, which was round, uniform dispersion, indicating that the preparation process is stable and feasible. The toxicity experiment showed that EA-CS-NPs maintained 80% cell viability, significantly higher than that of the NDNB group, indicating lower toxicity and better inhibitory effects on TGF-β1-stimulated MLg and NIH-3T3 cells. Wound healing assay results showed that the inhibitory effect of EA-CS-NPs on cell migration was more pronounced than that of EA in the same amount of EA-containing drugs. Drug uptake experiments revealed that EA-CS-NPs significantly enhanced drug uptake in MLg and NIH-3T3 cells. In vivo , Cy7-CS-NPs exhibited higher fluorescence intensity in rat lungs compared to Cy7 solution, indicating better lung retention. The in vivo efficacy test showed that compared with the EA group, EA-CS-NPs could better reduce the area of pulmonary fibrosis and collagen deposition, improve lung function, and have a longer retention time in the lung. In summary, our results revealed that EA-CS-NPs may be a good choice for the treatment of pulmonary fibrosis. Graphical
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COMPOSITES COMMUNICATIONS
·
2025
·
IF 7.7
Yanwen Xiao,Qiaoyu Huang,Yong Hu,Yige Chen,Man Zhou,Zhaoxia Chen,Xueliang Jiang,Yuhong Zhang
Creating conductive hydrogel flexible wearable sensors with excellent conductivity, adhesion, antibacterial and biocompatibility still poses a challenge. Herein, an electrically stable multifunctional poly (vinyl alcohol)/quaternary ammonium chitosan-lithium ion conducting hydrogel (PVA/HACC-Li + ) was fabricated. PVA-based hydrogels regulated by Li + and HACC have high electrical conductivity (12.35 ms/cm), high stretchability (∼372 %), excellent antibacterial properties, effectively inhibiting both Escherichia coli and Staphylococcus aureus, and very good biocompatibility (L929 cell survival rate of 108.76 %). Moreover, PVA/HACC-Li + hydrogel successfully serve as strain sensor, which can accurately identify different joint and subtle muscle movements signals of the human body with high sensitivity (GF = 2.42), wide sensing range (0–300 %) and fast response time (183 ms). Thus, this endeavor offers a feasible method for utilizing versatile multifunctional hydrogels in the field of motion monitoring and serves a practical reference for the diverse applications within wearable electronic skin.
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