FOOD HYDROCOLLOIDS
·
2022
·
IF 11.504
Peng Wang,Yucheng Zou,Yang Li,Zeyu Qin,Xingquan Liu,Hui Zhang
In this study, chitosan-dialdehyde-β-cyclodextrin-curcumin (CS-DCD-CUR) and alginate dialdehyde (ADA) were alternately deposited on the surface of electrospun cellulose acetate (CA) nanofibers driven by Schiff base bonding and electrostatic attraction. With the increasing number of bilayers, the self-assembled nanofibers showed an increased average fiber diameter from 441 to 576 nm and had relatively rough surfaces. The improved thermal stability and tensile strength of self-assembled nanofibers were attributed to the interactions between CS-DCD-CUR and ADA. The self-assembled nanofibers exhibited pH-sensitive release characteristics under acidic conditions due to the weakening of the electrostatic interaction and the hydrolysis of Schiff-base. Moreover, the self-assembled nanofibers could be used for sustained and controlled release of the curcumin within 620 min and maintained the antioxidant activities . The highest radical scavenging activities against ABTS and DPPH radicals of the nanofibers were 24.75% and 83.56%, respectively. These results suggested that the layer-by-layer self-assembled nanofibers provided a pH-responsive sustained delivery system for bioactive substances with potential applications in functional foods.
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高影响因子
Nanoscale
·
2022
·Vol. 14
·期 35
·12762-12772
·
IF 8.307
Ge Lv,Ziwei Wang,Wenjing Li,Guannan Zhu,Beibei Liu,Bin Song,Min Wu,Xiao Gong
To obtain multicolor carbonized polymer dots (CPDs), acid-assisted hydrothermal/solvothermal reactions are an effective strategy. However, the long wavelength fluorescence of boron–nitrogen codoped CPDs (BN-CPDs) is rarely reported. In this work, we used concentrated hydrochloric acid to regulate the fluorescence (from green to orange) of BN-CPDs via a solvothermal reaction. Meanwhile, 3-formylphenylboronic acid with a benzene ring structure was employed as the boron source, which helped the formation of the internal conjugated structure of CPDs to obtain long wavelength fluorescent CPDs. The fluorescence properties of BN-CPDs were investigated, which indicated the concentration- and solvent-dependent properties of the BN-CPDs. Based on the experimental results, we assume that the multicolor emission of the BN-CPDs originates from the synergistic effects of the degree of graphitization and surface states. Due to the special fluorescence properties of the BN-CPDs, pH sensing and trace water detection in dichloromethane solution can be effectively achieved. The results of the study reveal the potential of BN-CPDs in sensing applications.
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高影响因子
FOOD HYDROCOLLOIDS
·
2020
·
IF 7.053
Xingzhong Zhang,Xiaogang Luo,Yixiang Wang,Yan Li,Bin Li,Shilin Liu
In this work, concentrated Pickering emulsions had been prepared by using soybean protein isolate (SPI) and TEMPO-oxidized bacterial cellulose (TOBC) complex as solid stabilizers. The effects of solid particle content, pH and oil phase volume fraction on the morphology, stability and rheological behaviors of the emulsions had been investigated. It indicated that the emulsion droplets had uniform particle size distribution when the ratio of SPI/TOBC was controlled to 12.5:1 (wt/wt). The emulsification performance could be improved with the increase of solid complex particles content from 1.0% to 3.0%. Moreover, the pH played an important role in regulating the structure and properties of the emulsions. With microscopic observation, the emulsions at pH 7.0 had smaller droplet size (10–15 μm) than that (15–40 μm) of the emulsions at pH 3.0. While the emulsions at pH 3.0 maintained a low creaming index (CI) value than those at pH 7.0, and uniform cellular network structure could be seen by SEM observation. It suggested that the electrostatic complexation between soy proteins and anionic bacterial cellulose nanofibrils at pH 3.0 was more favorable for stabilizing emulsions than those at pH 7.0. This work would provide some guidance for regulating the properties of emulsions that stabilized by soy protein and cellulose nanofibrils.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Ruoyu Dai,Xipao Chen,Ning Ouyang,Yaoping Hu
Carbon dots (CDs) with tunable photoluminescence (PL), especially with long wavelength PL , offer great potential for various applications including sensing, bioimaging, photomedicine, and optoelectronic devices. Here, we use 2,3-diaminopyridine as a single precursor to synthesize colorful CDs in different pH conditions. By simply regulating the reaction media from alkali to neutral to acid, bright CDs emitting violet, green, and orange fluorescence are prepared, respectively. Detailed characterizations reveal that the red-shift of PL is caused by the growing size of sp 2 conjugated domain and increasing content of graphite nitrogen. We embed CDs in starch to suppress self-quenching and enhance the PL quantum yields. The CD/starch composites, possessing efficient solid-state fluorescence, can be coated on the ultraviolet chips (365 nm) to fabricate multicolor light-emitting diodes toward indoor illumination. This work presents a new strategy to adjust the PL wavelength of CDs in a wide range, and clarifies the emission mechanism.
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高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2019
·
IF 7.65
Suding Yan,Xinping Zhang,Hui Zhang
The combination of persulfate (PS) activation by iron ions with electrochemical process (electro/Fe 3+ /PS) is a promising advanced oxidation process. However, almost all these systems were performed in an unbuffered solution and actually under acidic pH condition, with the electricity being frequently supplied by external power. Considering the high buffering capacity of wastewater and energy saving, peroxydisulfate (PDS) activation by Fe(III) species with bioelectricity provided by microbial fuel cell (MFC) for bisphenol A (BPA) oxidation was investigated at fixed near-neutral pH as well as acidic pH. The results indicate that 90.8% of BPA could be removed at pH 2.5. Though the iron existed in the form of precipitate, BPA could still be efficiently removed at pH 6.0. The precipitate formed in the system at pH 6.0 was identified as the amorphous iron oxyhydroxides. Sulfate radicals in the bulk solution and that adsorbed on the precipitate were the dominant reactive species responsible for the oxidation of BPA in the homogeneous and heterogeneous MFC/Fe(III)/PDS processes, respectively. The mechanisms of BPA degradation at both pH values were proposed via EPR and quenching tests as well as XPS analysis. The effects of operating parameters, the mineralization, the mineralization current efficiency and energy consumption were also explored.
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高影响因子
MATERIALS AND CORROSION-WERKSTOFFE UND KORROSION
·
2018
·Vol. 69
·期 6
·736-748
·
IF 1.259
Xiaojie Liu,Weihua Li,Wei Wang,Liying Song,Weijie Fan,Xiang Gao,Chuansheng Xiong
Mesoporous micro- or nanocontainers have been indicated to be potential carriers of corrosion inhibitors to modify water-based coatings for self-healing properties and excellent anti-corrosion performance. In this work, the eco-friendly mesoporous chitosan microspheres loaded with green corrosion inhibitor sodium phytate were incorporated in self-healing water-based polyacrylate coating. The microspheres with mesoporous surface, uniform size, and promising pH responsiveness were prepared via the water-in-oil (W/O) emulsion chemical cross-linking method. On this basis, chitosan microspheres loaded with 25.79 wt% sodium phytate were obtained by negative pressure impregnation method and the pH-responsive was demonstrated by the electrochemical impedance spectroscopy (EIS). The results of EIS and seawater immersion tests revealed that artificial defected water-based polyacrylate coating containing 5 wt% chitosan microspheres showed high anti-corrosion performance and exhibited self-healing capabilities due to the release of corrosion inhibitor sodium phytate.
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高影响因子
Desalination and Water Treatment
·
2024
·
IF 1
Debo Wu,Xingmin Gao,Shuiping Yang,Winston Duo Wu
Sequential removal of phenol and As(V) from co-contaminated water by ferrate (Fe(VI)) was investigated. The results showed that a neutral pH condition favored the sequential of phenol and As(V) by Fe(VI). Around 70% of phenol was removed at neutral pHs with a Fe(VI): phenol molar ratio of 10:1. While about 50% of As(V) was finally removed under similar conditions. The presence of a high concentration of Cl – (up to 0.2 M) showed 6% inhibitory effect on the final removal percentage of phenol compared to that without Cl – . Fourier transform infrared spectroscopy, X-ray powder diffraction, and X-ray photoelectron spectroscopy analyses suggested that As(V) was removed through adsorption by the precipitates (amorphous iron (oxy)hydroxide), while phenol was removed via degradation (89%) and adsorption (11%), respectively. Removal of As(V) occurred immediately when phenol degradation was initiated, indicating a rapid generation of Fe(III)- (oxy)hydroxide. Our study also revealed that an excessive amount of Fe(III) ions in the aqueous phase did not facilitate the degradation of phenol. On the other hand, improving the precipitation rate of Fe(III) could further improve the removal efficiency of phenol and As(V).
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高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2016
·Vol. 16
·期 12
·12517-12525
·
IF 1.338
Xiao Xin,Liu Chao,Zuo Xiaoxi,Liu Jianju,Nan Junmin
Flower-like BiOCl microspheres are synthesized by a microwave route, and their pH-dependent adsorption and recovery of methylene blue (MB) are studied. The as-synthesized BiOCl exhibits hierarchical structures with dominant {001} facets, a specific surface area of 36.39 m2
g−1, and mesoporous approximately 18 nm in diameter. Compared with BiOCl nanoplates, the adsorption of MB (20 mg L−1, pH = 6.8) over the BiOCl microspheres increases from 21% to 98.2% after only 2 min using an adsorbent dosage of 1 g L−1.
The excellent adsorption capacity, i.e., a maximum capacity of 24.2 mg g−1 and 26.2 mg g−1 at pH = 6.8 and 3.5, respectively, is attributed to the negatively charged facets, high surface area, and unique defects/vacancies and micro/nanostructures of as-synthesized
material. In addition, the adsorption of MB at pH = 11.9 is only approximately 1/14 of that at pH less than 6.8, indicating the pH-dependent adsorption behavior of the BiOCl. Thus, the BiOCl microspheres are regarded as a promising green pH-dependent adsorbent, and the adsorbed MB is recovered
instead of degraded. The pH-dependent adsorption behavior for MB over the BiOCl is demonstrated to be closely related with not only the unique surface of the BiOCl microspheres but also the polarity of MB in different solution pH.
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高影响因子
Nanoscale Advances
·
2025
·
IF 4.6
Weibo Xu,Xiaohan Li,Fujin He,Han Zhao,Jing Wu,Mengyu Li,Xiaoying Dai,Yanmin Li,Xiaojiao Hu,Xiao-Dong Li,Juan Cen,Peng Guo,Shaofeng Duan
Prostate cancer (PCa) is the most common cancer in men and the leading cause of cancer death worldwide. Overactivation of PI3K signaling has been reported to be associated with PCa. TGX221 is an effective specific inhibitor of PI3K, but its clinical application is greatly limited due to its poor solubility. Herein, by using folic acid-PEG-cholesterol semi-succinate (FA-PEG-CHEMS) as the targeting component, we developed a folate receptor-targeted pH-sensitive liposomal delivery system loaded with TGX221 (FA-Lip-TGX221) that could realize effective delivery and controlled release of drugs in the tumor. The prepared liposomes exhibited a uniform particle size and high stability. In addition, FA-Lip-TGX221 could be effectively internalized by PC-3 cells due to its ability to target folate receptors, thereby accumulating in tumor issues. Meanwhile, in vitro and in vivo experiments suggested that FA-Lip-TGX221 could activate PERK-ATF4-CHOP signaling pathway by inhibiting PI3K/110β signaling in PCa, thus significantly promoting endoplasmic reticulum (ER) stress-mediated cancer cell death. In conclusion, FA-Lip-TGX221 is a promising nano delivery vehicle for the treatment of PCa, and also provides new ideas for all tumors overexpressing folate receptors.
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PubMed
高影响因子
BIOMACROMOLECULES
·
2015
·
IF 5.75
Menglin Wang,Jin Sun,Yinglei Zhai,He Lian,Cong Luo,Lin Li,Yuqian Du,Dong Zhang,Wenya Ding,Shuhong Qiu,Yuhai Liu,Longfa Kou,Xiangfei Han,Rongwu Xiang,Yongjun Wang,Zhonggui He
To improve the bioavailability of orally administered drugs, we synthesized a pH-sensitive polymer (poly(ethylene glycol)–poly(2-methyl-2-carboxyl-propylene carbonate)–vitamin E, mPEG–PCC–VE) attempting to integrate the advantages of enteric coating and P-glycoprotein (P-gp) inhibition. The aliphatic polycarbonate chain was functionalized with carboxyl groups and vitamin E via postpolymerization modification. Optimized by comparison and central composite design, mPEG113–PCC32–VE4 exhibited low critical micelle concentration of 1.7 × 10–6 mg/mL and high drug loading ability for tacrolimus (21.2% ± 2.7%, w/w). The pH-responsive profile was demonstrated by pH-dependent swelling and in vitro drug release. Less than 4.0% tacrolimus was released under simulated gastric fluid after 2.5 h, whereas an immediate release was observed under simulated intestinal fluid. The mPEG113–PCC32–VE4 micelles significantly increased the absorption of P-gp substrate tacrolimus in the whole intestine. The oral bioavailability of tacrolimus micelles was 6-fold higher than that of tacrolimus solution in rats. This enteric polymer therefore has the potential to become a useful nanoscale carrier for oral delivery of drugs.
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产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2018
·
IF 3.997
Linlin Wang,Wei Dai,Meng Yang,Xinran Wei,Ke Ma,Botao Song,Pengxiang Jia,Yongkuan Gong,Jingfa Yang,Jiang Zhao
In this study, we modified the well-known photothermal polydopamine nanoparticles with the poly[(2-methacryloyloxy)ethyl phosphorylcholine- b -(2-dimethylamino)ethyl methacrylate] (PMPC- b -PDMAEMA) diblock copolymers, containing both biocompatible cell membrane phosphorylcholine zwitterions segments and pH-responsive dimethylaminoethyl units on the polymer chains, to achieve both the photothermal property and pH-responsive release behavior. The results showed that the obtained nanoparticles had a narrow size distribution with the diameter about 220 nm. Besides, the modified polydopamine nanoparticles showed enhanced colloidal stability, pH-sensitive drug release behavior, excellent biocompatibility and remarkable near-infrared photothermal property. Thus, it is highly anticipated that PMPC- b -PDMAEMA modified polydopamine nanoparticles can serve as a powerful drug delivery system for combined pH-sensitive drug release and near-infrared photothermal therapeutic.
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产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Lu Mu,Huihui Wang,Zihao Zhang,Hong-Man Hou,Gong-Liang Zhang,Hongshun Hao,Jingran Bi
Monitoring food freshness is considerably important for food safety. In this study, a smart pH-responsive fluorescence hydroxypropyl methyl cellulose-κ-carrageenan-fluorescein isothiocyanate-NH 2 -CaAl 2 O 4 (H-K-F-N) film was prepared. Taking synergetic advantage of the pH-dependent behavior of fluorescein isothiocyanate dye and the luminescence characteristics of calcium aluminate phosphor, the film exhibited a unique strong pH-responsive fluorescence with an exceptional linear relationship (correlation coefficient, R 2 = 0.9993) across a wide pH rang of 2.0–12.0. Moreover, the H-K-F-N film, as a smart sensor, could be used to estimate the total volatile basic nitrogen and total viable count through fluorescence intensity based on the partial least squares regression model and support vector machine regression, respectively. Leveraging the relationship between the fluorescent image's digital signals and food freshness indicators, a smartphone-assisted system was developed. These results demonstrated that H-K-F-N film is promising for applications in intelligent food packaging and food safety monitoring.
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高影响因子
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