Frontiers in Sustainable Food Systems
·
2025
·
IF 3.1
Chang Ma,Hooi Tin Ong,Hoon Koon Teoh,Yue Ling Wang,Zhong Han Zhu,Yan Liu,Juan Du
Background: T-2 toxin is a highly toxic mycotoxin that poses serious risks to food safety and human health. There is an urgent need for sensitive, selective, and reliable analytical methods for its detection in complex food matrices.Methods: We developed a novel ratiometric fluorescence immunoassay based on gold nanoparticles encapsulated in manganese dioxide nanosheets (AuNP@MnO₂), which exhibit intrinsic oxidase-like activity. The assay utilizes dual-emission fluorescence (at 430 nm and 570 nm) and quantifies T-2 toxin by measuring the fluorescence intensity ratio (F₄₃₀/F₅₇₀), thereby minimizing environmental and instrumental variability.Results: The method demonstrated excellent linearity over a wide concentration range (0.082–60.00 ng/mL) with a low detection limit of 0.068 ng/mL. High specificity was achieved, showing negligible cross-reactivity against common mycotoxins such as aflatoxin B₁, zearalenone, fumonisin B₁, ochratoxin A, and deoxynivalenol. In spiked corn samples, recoveries ranged from 76.94% to 99.48%, confirming good accuracy, stability, and reproducibility.Conclusion: This ratiometric immunoassay significantly enhances detection precision by self-calibrating through an internal fluorescence reference. Its simplicity, sensitivity, and robustness in real food samples make it a promising tool for rapid and reliable monitoring of T-2 toxin in food safety applications.
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JOURNAL OF HAZARDOUS MATERIALS
·
2025
·
IF 11.3
Hongling Bu,Hanjie Chen,Chengshuai Liu,Hui Tong,Yanfu Wei,Meiqing Chen,Ziming Xu,Jianbo Chen,Peng Yuan
The oxidative transformation of arsenite (As(III)) by iron-bearing clay minerals is a critical process mitigating arsenic mobility and toxicity in aquifers. However, the molecular-scale mechanisms underlying the distinct efficiencies among different clay types remain poorly constrained. Herein, employing synthetic Fe(II)-rich analogues (2:1-type montmorillonite (SIP-1) and 1:1-type kaolinite (SIP-2)), we demonstrate that the expandable 2:1 structure of SIP-1 facilitates a sustained and multi-pathway oxidation process, achieving superior As(III) oxidation (60%) and removal (>99%) under neutral-to-acidic conditions. A suite of evidence confirms that its nanoconfined interlayer microenvironment not only enables direct electron transfer from structural Fe(II) to As(III) but also stabilizes reactive intermediates (ROS and Fe(IV)), thereby inhibiting surface passivation. In contrast, the non-expandable 1:1 structure of SIP-2 constrains oxidation to external surfaces, leading to rapid deactivation via irreversible passivation, with its maximum efficiency shifting to alkaline conditions (76% removal, pH 8). Our findings establish that the crystal structure dictates the interfacial oxidation mechanism and long-term performance, overriding the influence of iron content alone. This mechanistic understanding provides a predictive framework for arsenic fate in heterogeneous subsurface environments and a fundamental principle for designing high-performance, clay-based remediation materials.
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DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Mei Yang,Jingtian Yang,Ruobing Pi,Yunlong Zhou,Meng Sun,Jiang Liu
In the context of the “dual carbon” goals, the development of sustainable photocatalytic systems for carbon dioxide (CO 2 ) reduction is critical for alleviating energy scarcity while mitigating carbon emissions. Utilizing agricultural waste biomass in photocatalytic systems supports the recycling of biomass resources and mitigates the environmental issues caused by stalk burning. In this study, carbon quantum dots (CQDs) with nitrogen and phosphorus doping (NP-CQDs) were prepared by a hydrothermal approach using corn stalks as the carbon source. The NP-CQDs were then incorporated into a composite with graphitic carbon nitride (g-C 3 N 4 ) and nickel hydroxide (Ni(OH) 2 ), successfully obtaining the ternary catalyst of CN/Ni/NP-CQDs. The optimal ratio composite material of CN/Ni/NP-CQDs-4 demonstrates excellent CO 2 reduction performance, exhibiting the CO and CH 4 production rates of 14.24 and 0.73 μmol g −1 h −1 , which are 10.02 and 2.28 times that of pure g-C 3 N 4 . The CN/Ni/NP-CQDs-4 has a relatively large specific surface area, which can provide more active sites and improve the CO 2 reduction efficiency. EPR results show that the Z-scheme heterojunction formed by g-C 3 N 4 and Ni(OH) 2 can effectively suppress the recombination of photogenerated carriers. NP-CQDs serve as an electron mediator, thereby enhancing photogenerated charge transfer capability. This study successfully combines biomass corn stalk derivatives with traditional photocatalytic materials, thereby addressing the challenge of utilizing agricultural waste valorization while reducing the cost of the photocatalytic system. This study provides new insights for constructing a green and sustainable CO 2 reduction photocatalytic system.
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EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
·
2024
·
IF 6
Zhiran Ju,Junde Xu,Keshuang Tang,Fener Chen
COX-2/NLPR3-targeted therapy might be beneficial for the inflammation diseases. To discover novel anti-inflammatory compounds with favorable safety profiles, three new series of non-carboxylic diclofenac analogues bearing various ring systems, such as oxadiazoles 4a - 4w , triazoles 6a - 6m , and cyclic imides 7a and 7b , were synthesized. The synthesized analogues were evaluated for their inhibitory activity against COX-2 enzyme. Among them, compound 6k exhibited potent selective COX-2 inhibition (IC 50 = 1.53 μM; selectivity ((IC 50 (COX-1)/IC 50 (COX-2) = 17.19). Treatment with compound 6k effectively suppressed the NF-κB/NLRP3 signaling pathway, resulting in reduced expression of pro-inflammatory factors. The in vivo ulcerative colitis assay demonstrated that compound 6k significantly ameliorated histological damages and showed strong protection against DSS-induced acute colitis. The collected results indicated that compound 6k displays anti-inflammatory activity through COX-2/NLRP3 inhibition. Therefore, compound 6k represents a promising candidate for further development as a new lead compound with reduced colitis side effects.
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高影响因子
Canadian Journal of Chemistry
·
2022
·Vol. 100
·期 6
·
IF 1.051
Junyong Sun,Xian Liu,Like Chen,Lijun Peng,Xitian Peng,Tian Gan
Herein, polyvinylpyrrolidone-stabilized Au nanorods were controllably implanted into ZIF-8 to form a well-uniformed AuNRs@ZIF-8 electrocatalyst with a multicore-shell structure. After characterizing the chemical and physical properties, a novel electrochemical sensing platform was fabricated for 2-chlorophenol (2-CP) monitoring based on the AuNRs@ZIF-8 modified glassy carbon electrode. Due to the unique electrochemical property of AuNRs cores and ultra-porous architecture of ZIF-8 shell, the electrocatalyst would effectively accelerate the electron transfer and greatly improve the electrochemical response of 2-CP. Under the optimized experimental conditions, the oxidation peak current of 2-CP enhanced linearly with the increase of its concentration between 0.010 and 40 μM, and the limit of detection was 3.6 nM based on S/N = 3. Meanwhile, the prepared AuNRs@ZIF-8 electrode showed favorable stability, reproducibility, and selectivity, which could be applied to the accurate analysis of 2-CP in aquaculture with standard addition recovery ranging from 96.67% to 104.0%.
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JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2018
·Vol. 18
·期 4
·2914-2920
·
IF 1.354
Li Jie,Zhang Jia,Chen Lianxi,Wang Yu,Liu Zhenhui
A new effective surface poly(1-vinyl-2-pyrrolidone) (PVP) grafted layer protected selective etching strategy has been used for preparing vinyl functionalized porous silica nanospheres (V-PSNSs). The main reaction mechanism was relied on the vinyl groups distributed on the surface of
outer vinyl silica nanospheres (V-SiO2) which can be polymerized with another vinyl monomer, such as 1-vinyl-2-pyrrolidone (VP), in the presence of initiator. It was observed from the research results that only grafting PVP on the surface of outer vinyl silica nanospheres (V-SiO2)
can V-PSNSs be obtained, because grafting PVP was able to protect outer V-SiO2 from being etched prior to inner pure silica (sSiO2). In addition, effect of the amounts of sSiO2@V-SiO2 as another monomer substrate on the formation of PVP grafted sSiO2@V-SiO2
(sSiO2@V-SiO2/PVP) was discussed. The results showed that the less of the sSiO2@V-SiO2 amounts, the thinner of the PVP grafted layer on the surface of sSiO2@V-SiO2, the poorer protection ability of the surface. In the present
study, V-PSNSs with 29 m2g−1 of BET surface areas and 0.1 cm3g−1 pore volumes were successfully synthesized by grafting 0.3 g of VP on the surface of 0.3 g of sSiO2@V-SiO2 and subsequent etching.
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CHINESE JOURNAL OF CATALYSIS
·
2014
·
IF 1.552
Zhongkui Zhao,Renzhi Li,Yu Li
A clean and highly efficient synthesis of 1-amino-2-acetylanthraquinone via reductive isoxazole ring cleavage of 3-methylanthra[1,2- c ]isoxazole-6,11-dione catalyzed by trace copper using hydrazine hydrate as a clean reducing agent and water as a green reaction medium under mild reaction conditions was investigated. Various transition-metal catalysts were screened for the reductive ring-opening reaction, and Cu(NO 3 ) 2 was shown to be an excellent catalyst. A conversion of 97.2% and 1-amino-2-acetylanthraquinone selectivity greater than 95% were obtained in the presence of 2.6 mol% Cu(NO 3 ) 2 (turnover number 38) with 1.3 equiv. of hydrazine hydrate for 2 h in water. The structure of the product was confirmed by 1 H nuclear magnetic resonance spectroscopy and mass spectrometry ; the main byproduct was hydroxyl-substituted 1-amino-2-acetylanthraquinone. A possible reaction mechanism for the copper-catalyzed ring cleavage of 3-methylanthra[1,2- c ]isoxazole-6,11-dione with hydrazine hydrate was proposed.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2021
·
IF 5.316
Xiao-Yu Zhong,Gui-Wei Yan,Zhi-Hui Chen
Lead-free ferroelectric ceramics of (1-x)Ba 0.98 Li 0.02 TiO 3 -xBi(Mg 1/2 Sn 1/2 )O 3 (abbreviated as (1-x)BLT-xBMS, x = 0, 0.02, 0.04, 0.05, 0.06, 0.08) were synthesized through conventional solid-state sintering method. The effects of Bi(Mg 1/2 Sn 1/2 )O 3 addition on the phase transition, microstructure, the dielectric properties and the energy storage properties were investigated. All the BLT-BMS samples exhibited single phase perovskite structure. XRD and Roman spectrum confirmed the coexistence of the orthorhombic phase and tetragonal phase in the samples with x = 0.00–0.05, which turned to the coexistence of orthorhombic and cubic phase in the samples with x > 0.05. All the samples display dense microstructures with clear grain boundaries. The average grain size of the samples increases and the relaxor characteristics become stronger with the addition of BMS. The existence of orthorhombic phase apparently promotes the energy storage performance. The maximum energy density of 0.16 J/cm 3 and the largest energy efficiency of 70.42% were achieved with orthorhombic/tetragonal ratio of 53/47 at x = 0.05.
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ZEITSCHRIFT FUR NATURFORSCHUNG SECTION A-A JOURNAL OF PHYSICAL SCIENCES
·
2023
·Vol. 78
·期 10
·921-926
·
IF 1.8
Cong Liu,Junshen Xing,Zheng Liu,Wenlin Feng
BaSr 2 (PO 4 ) 2 : 4 %Eu 3+ , 4 % A ( A = Li + , Na + , K + ) phosphors were prepared by high-temperature solid-phase method. The crystal structure, photoluminescence properties, thermal stability, chromaticity coordinates, and fluorescence lifetime of the samples were investigated. The excitation and emission spectra of the samples are broadbands and the maximum peak of the emission spectrum is located at 619 nm. Among three charge compensators, the luminescence intensity is optimal for Li + co-doping case, and the quenching temperature of the typical sample is about 500 K. the fluorescence lifetime
τ
is 1469.6 ns, and the chromaticity coordinates exhibit a strong red emission. The present phosphor has a potential application for white light-emitting diodes (LEDs) under the near-ultra violet (n-UV) light excitation.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2019
·
IF 5.107
Rui Wang,Xingang Li,Jian Na,Yan Wu,Runnan Zhao,Yutao Yan,Hong Li,Xin Gao
Reversible reaction-assisted technology for ethanediol (EG) and 1, 2-butanediol(1,2-BDO) azotropic mixture separation was proved effective. However, the missing acetalization kinetic parameters hinder the process design and industrialization. This paper addresses the competitive kinetics of EG and 1,2-BDO mixture towards propyl aldehyde. The reaction mechanism was illustrated, and the impacts of feed composition, temperature and solution inhomogeneity were explored. The pseudo-homogeneous model was derived for the system, and the kinetic parameters were obtained. Results demonstrated that the aldehyde and 2-ethyl-1,3-dioxione (2ED) inputs were crucial manipulation variables for reversible reaction-assisted separating (RRAS) process design. The RRAS process was proposed, based on the competitive kinetics, to evaluate the techno-economic performance of RRAS. Two promising processes, which differed in the conversion of EG, were proposed to implement the separation. The economic evaluation revealed that the flowsheet with EG and 1,2-BDO both being converted to acetals and EG then being recovered through 2ED hydrolyzation, has more potential for industrial application.
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DALTON TRANSACTIONS
·
2019
·Vol. 49
·期 12
·3743-3749
·
IF 4.052
Ruling Tang,Chunli Hu,Jianghe Feng,Zhi Fang,Yan Chen,Fang Kong,Jianggao Mao
Two new inorganic metal borate derivatives, Sr5TeO2(BO3)4 and NaSr5(BO3)(SiO4)2, have been obtained through a high temperature solid reaction method. Sr5TeO2(BO3)4 crystallizes in a tetragonal space group of P4/mnc featuring a three-dimensional (3D) structure composed of a porous 3D strontium framework stabilized by the unique zero-dimensional (0D) [TeO2(BO3)4]10− anions. NaSr5(BO3)(SiO4)2 crystallizes in a monoclinic space group of P21/c with a 3D structure consisting of a splendid strontium 3D framework strengthened by isolated BO3 and SiO4 groups. The sodium cations located in the empty space of the structure. Thermal stability analyses, optical property measurements and theoretical studies of the compounds were performed. Refractive index calculations revealed that the birefringence of Sr5TeO2(BO3)4 and NaSr5(BO3)(SiO4)2 is 0.048 and 0.029, respectively, at 1064 nm.
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NEW JOURNAL OF CHEMISTRY
·
2016
·Vol. 40
·期 3
·2333-2342
·
IF 3.277
Qunbo Mei,Ruqiang Tian,Yujie Shi,Qingfang Hua,Chen Chen,Bihai Tong
Different types of fluorescent probes for Hg2+ based on the 5-thiophen-2-yl-benzothiazole derivatives (TBT, 2-thiophen-2-yl-benzothiazole; CTBT, 9-(5-benzothiazol-2-yl-thiophen-2-yl)-9H-carbazole; DTBT, 2-(5-acenaphthen-5-yl-thiophen-2-yl)-benzothiazole; and NTBT, 6-(5-benzothiazol-2-yl-thiophen-2-yl)-2-hexyl-benzo[de]isoquinoline-1,3-dione) were realized by changing the subsituents. Multisignaling changes were observed through UV-vis absorption and fluorescence spectra upon addition of Hg2+. The addition of Hg2+ on TBT induced a remarkable OFF/ON-type fluorescence signaling behavior. With the introduction of electron-donating carbazole, the detection behavior of CTBT was just the reverse of what TBT displayed, while a ratiometric fluorescent probe based on DTBT for Hg2+ was prepared by introducing the weak electron-drawing group acenaphthene. Moreover, the dichloromethane solution of CTBT and DTBT showed a distinct color change from colorless to yellow with the addition of Hg2+, which indicated that these two probes would facilitate the naked-eye detection of Hg2+. However, both UV-vis absorption and fluorescence spectra of NTBT with strong electron-withdrawing substituents showed no obvious change upon addition of Hg2+. It would be concluded that the electronic properties of the molecule was one of the vital factors in designing chemosensor molecules.
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