JOURNAL OF MATERIALS SCIENCE
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2026
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IF 4.4
Hou Chaojie,Xu Hang,Zhang Bingbing,Zhao Yuan,Wu Fengmin
A flower-like core–shell MnO 2 @CeO 2 composite was synthesized via hydrothermal method. Characterization by X-ray diffraction, Brunauer–Emmett–Teller, scanning electron microscopy, transmission electron microscopy, and X-ray photoelectron spectroscopy confirmed a micro-spherical morphology with a high specific surface area (266.4 m 2 g −1 ) and well-defined mesoporous structure (average pore size: 7.4 nm), facilitating active site exposure and reactant adsorption. Under optimal conditions (25 mg catalyst, 1.5 mL 25 wt% peroxymonosulfate, 2 mL acetonitrile, 600 ppm initial sulfur, 40℃), the desulfurization efficiency for dibenzothiophene reached 81.26%. It maintained 71% efficiency after 5 cycles, with stable chemical structure and morphology. Quenching experiments confirm that the primary oxidation of dibenzothiophene to dibenzothiophene sulfoxide is predominantly mediated by sulfate radicals (·SO 4 ⁻), while the subsequent oxidation of dibenzothiophene sulfoxide to dibenzothiophene sulfone relies primarily on hydroxyl radicals (·OH). Kinetic analysis showed tandem reaction behavior with rate constants k 1 = 0.213 min⁻ 1 and k 2 = 0.187 min⁻ 1 . This catalyst offers promising potential for industrial production of ultra-low-sulfur fuels. Graphical
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TRANSITION METAL CHEMISTRY
·
2026
·Vol. 51
·期 3
·35
·
IF 2.8
Liu Chao,Bi Xue-bin,Xu Jia-yu,Liu Rui-xue,Zhang Shu-feng
Two new metal complexes 9-AIH-Co and 9-AIH-Zn, were synthesized using ( Z )-2-(2-(anthracen-9-ylmethylene)hydrazineyl)-4,5-dihydro-1 H -imidazole (9-AIH) as the ligand and evaluated as anticancer agents. Their structures were determined by single-crystal X-ray diffraction, elemental analysis and mass spectroscopy. The 9-AIH ligand crystallized in acetate form within the orthorhombic crystal system with space group P na2 1 . The cobalt complex, 9-AIH-Co, is a mononuclear complex with chloride counterions, adopting a tetrahedral coordination geometry and crystallizing in the monoclinic system with space group P2 1 /n. Similarly, the zinc complex, 9-AIH-Zn, with acetate counterions, also exhibits a tetrahedral configuration but crystallizes in the monoclinic system with space group C2/c. Anticancer activity assays revealed that 9-AIH-Co demonstrated significant inhibitory effects against three representative tumor cell lines, MGC-803 (gastric cancer), SK-OV-3 (ovarian cancer), and HepG-2 (liver cancer), which were selected for their clinical relevance as models for prevalent and challenging solid tumors. The IC 50 values were 6.45 ± 0.78, 8.28 ± 0.80 and 8.87 ± 2.26 µM, respectively, showing superior activity compared to both the free ligand 9-AIH and the 9-AIH-Zn. In vitro antibacterial tests indicated that 9-AIH-Co possessed antimicrobial properties similar to those of 9-AIH against four common pathogenic bacteria, including Bacillus subtilis , with MIC values ranging from 3.9 to 7.8 µg/mL. Conversely, 9-AIH-Zn showed markedly diminished antibacterial effects, with the MIC value of 125 µg/mL. These findings collectively suggest that metal ions play a pivotal role in modulating the comprehensive biological activities of metal complexes. The coordination of imidazole with Co(II) synergistically enhances both anticancer and antibacterial activities, whereas Zn(II) appears more appropriate for developing complexes with lower cytotoxicity. This research provides fundamental insights into the metal-ion-specific behavior of anthrahydrazone complexes, highlighting cobalt coordination as a promising strategy for developing dual-functional metallodrugs.
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Journal of Ocean University of China
·
2026
·Vol. 25
·期 2
·586-598
·
IF 1.6
Zeng Chu,Lyu Likang,Liu Mengqun,Yang Xiaodong,Zhao Hongkui,Wen Haishen,Li Jifang,Qi Xin
Caspase-9, the most intensively studied caspase, plays a crucial role in mitochondrial or intrinsic apoptosis of mammals as a protease. To explore the role of caspase-9 in fish, we cloned casp9 gene from rainbow trout ( Oncorhynchus mykiss ) and studied its characteristic and functions. Our in vivo experiments revealed that casp9 expression was significantly upregulated 24 h after bacterial challenge in the gills, accompanied by notable histopathological changes and apoptosis signals. Gene cloning identified that rainbow trout caspase-9 is a 455 amino acid protein encoded by a 1368 bp gene, characterized by a conserved CARD domain, as well as prominent large (P20) and small (P10) subunits. Functional assays of recombinant rainbow trout caspase-9 (rcaspase-9) showed dose-dependent proteolytic activity, with significantly higher activity at 2 mg/mL than at 0.2 mg/mL. Conversely, the CARD domain-deleted version exhibited minimal activity even at 2 mg/mL, demonstrating that the CARD domain is indispensable for homodimerization and self-activation. Additionally, RT-qPCR results indicated that casp9 was mainly expressed in gills and spleen. In vitro studies demonstrated significant upregulation of casp9, apaf-1 and cyt c , along with downregulation of bcl-2 in primary gill cells in response to LPS, peptidoglycan and poly I:C stimulation. Furthermore, rcaspase-9 induced upregulation of casp6 and casp7 in these cells. These findings underscore the importance of caspase-9 in immune defense and apoptosis triggered by pathogens in rainbow trout.
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IONICS
·
2026
·
IF 3.4
Hou Kangwei,Chang Xinhao,Li Xiaolin,Wang Li,Liang Guangchuan
The development of high-performance anode materials is crucial for lithium-ion battery. This work presents a strategic design of carbon quantum dots (CQDs) modified amorphous-dominated high-entropy oxide (FeCoNiCrMn) 3 O 4 (FCNCMO) synthesized via a combined hydrothermal and calcination approach as anode material for lithium-ions batteries. Systematic characterization reveals that CQDs form conductive bridges between particles, not only enhancing interparticle electron transport but also acting as an elastic buffer layer to suppress volume variations during cycling, while simultaneously refining the particle size from 433.6 nm (pristine FCNCMO) to 254.8 nm (FCNCMO/CQDs-10) and preventing particle aggregation to provide larger specific surface area 330.38 m 2 g − 1 , thereby providing more active sites for electrochemical reactions. Electrochemical tests demonstrate that the optimal FCNCMO/CQDs-10 composite delivers a high discharge capacity of 515.9 mAh g − 1 after 200 cycles at 200 mA g − 1 , significantly surpassing pristine FCNCMO (302.1 mAh g − 1 ). This composite also exhibits outstanding rate capability, delivering 190.2 mAh g − 1 at high current density of 2 A g − 1 while recovering to 831.6 mAh g − 1 when current density returns to 0.1 A g − 1 . This study provides a valuable strategy of stabilizing amorphous-dominated structures for developing high-performance HEO anodes.
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Clinical Oral Investigations
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2026
·Vol. 30
·期 3
·96
·
IF 3.6
Zhang Suqin,Yang Xinyu,Liu Ting,Xie Haifeng,Chen Chen
Objectives This study aims to investigate how the molecular weight, steric hindrance, number of phenolic hydroxyl groups, and their spatial arrangement in four polyphenols influence the inhibition of matrix metalloproteinase (MMP) activity and the promotion of collagen cross-linking and remineralization through polyphenol pre-treatment, and further analyze how these effects enhance the stability of the hybrid layer. Materials and methods Resin-dentin bonding specimens, collagen membranes, and demineralized dentin slices were prepared with/without pretreatment using four polyphenols: myricetin, resveratrol, proanthocyanidins (PA), and tannic acid, representing stilbenes, flavonoids, condensed tannins, and tannins. Then the microtensile bond strength (µTBS), nanoleakage, and in situ zymography were evaluated. The ability of polyphenols to inhibit MMP activity, promote collagen cross-linking and remineralization was assessed through quantitative MMP activity assays, hydroxyproline assays, cross-linking degree measurements, transmission electron microscopy (TEM), Zeta potential measurements, X-ray diffraction (XRD), and attenuated total reflectance-fourier transform infrared spectroscopy (ATR-FTIR). Results Among the four polyphenols, PA and myricetin demonstrated the strongest bonding enhancement by significantly increasing µTBS, reducing nanoleakage, and inhibiting MMP-9. PA and tannic acid were the most effective in promoting collagen cross-linking, while PA and myricetin showed the best remineralization capacity. Conclusions All four polyphenols promoted collagen cross-linking, inhibited MMP activity, and enhanced remineralization; PA and myricetin ultimately led to more significant increases in µTBS and reductions in nanoleakage. Clinical relevance PA and myricetin have better capabilities for enhancing bonding durability, which is very valuable for future screening of suitable polyphenols and even designing and synthesizing better-performing polyphenol structures artificially.
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RESEARCH ON CHEMICAL INTERMEDIATES
·
2026
·
IF 3.3
Tian Si,Su Zhen,Ge Yuansheng,Su Zhiwei,Shen Feng,Tong Gui,Liang Xiaoyang,Jiang Zhenjie,Zhang Lixin,Guan Qingqing
The catalytic cracking of high-boiling chlorosilanes, such as Si 2 Cl 6 —common by-products in polysilicon production—into lower-boiling-point chlorosilanes is essential for their reuse. However, conventional liquid-phase amine catalysts suffer from limited durability and low economic viability due to deactivation caused by metal impurities such as Al 3+ and Ti 4+ . In this work, a novel solid-state guanidine-grafted Merrifield resin (G-M-resin) catalyst was successfully synthesized via nucleophilic substitution. Significantly, the newly developed G-M-resin catalyst exhibits excellent durability, high efficiency , and recyclability in the catalytic cracking of Si 2 Cl 6 . After five reaction cycles, the G-M-resin catalyst maintains high catalytic efficiency, with only a 9% loss in the presence of Al 3+ and a 23.6% loss with both Al 3+ and Ti 4+ . In contrast, a conventional organic amine catalyst suffered a 40.8% loss of activity under Al 3+ and was completely deactivated when both metal ions were present. The superior stability of the G-M-resin catalyst originates from the low binding energy between the grafted guanidine groups and the interfering metal ions (Ti 4+ and Al 3+ ), thereby effectively preserving the active sites from deactivation. Furthermore, the solid-state design of the G-M-resin catalyst facilitates its regeneration, allowing for full recovery of initial performance after reactivation. This addresses a key limitation associated with conventional liquid amine catalysts. This work presents a durable and regenerable solid catalyst for converting high-boiling chlorosilanes, offering a promising strategy for maintaining catalytic activity in challenging environments.
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Scientific Reports
·
2026
·
IF 4.9
Zhang Yanming,Wu Wenjia,Meng Ting,Yang Shuiping,Miao Gong
This study aimed to investigate the role of miR-25-3p carried by human amnion epithelial cell (hAEC)–derived exosomes in regulating MUC5AC production and apoptosis in conjunctival goblet cells. hAEC-derived exosomes were isolated, characterized, and evaluated for their uptake by conjunctival goblet cells. qRT-PCR, flow cytometry, Western blotting, and ELISA were used to assess the effects of exosomes on MUC5AC expression and apoptosis, with a focus on the contribution of miR-25-3p. The interaction between miR-25-3p and its predicted target BCL2L11 was examined using dual-luciferase reporter assays. Conjunctival goblet cells efficiently internalized hAEC-derived exosomes. Exosome treatment increased MUC5AC expression ( P < 0.01) and reduced apoptosis ( P < 0.01). miR-25-3p was found to mediate these effects, at least in part, through targeting BCL2L11, thereby promoting MUC5AC production ( P < 0.01) and decreasing apoptosis ( P < 0.01). hAEC-derived exosomes, particularly those containing miR-25-3p, modulate mucin expression and apoptosis in conjunctival goblet cells. These findings provide mechanistic insight into how exosomal miRNAs may contribute to maintaining ocular surface homeostasis, suggesting a potential role for exosomal miR-25-3p in supporting ocular surface health.
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FIBERS AND POLYMERS
·
2026
·
IF 3.1
Xing Luyi,Lin Tao,Yin Xuefeng,Qu Sitian,Peng Guoqiang,Li Chenyang
Highly conductive hydrogel electrolytes have substantially promoted the advancement of flexible electronic devices. For such electrolytes, addressing the intrinsic trade-off between mechanical integrity and electrical conductivity is crucial for achieving optimal performance. This study investigates a composite hydrogel composed of cellulose nanofiber (CNF) and polyacrylamide (PAM), in which the interaction between CNF and PAM forms a stable structural network and facilitates efficient ion transport pathways. Furthermore, the incorporation of ferrous acetate (Fe(CH₃COO)₂) encapsulated within β-cyclodextrin (β-CD@Fe) into the hydrogel matrix markedly improves the ionic conductivity and enables a favorable balance between mechanical strength and electrical conductivity. As a result of this innovative design, the hydrogel exhibits excellent electrochemical properties, including an ionic conductivity of 0.0514 S cm −1 and a specific capacitance of 37.8 F cm −2 . Notably, the hydrogel maintains excellent cycling stability, retaining a Coulombic efficiency of 97.32% after 2000 charge–discharge cycles. Coupled with its combination of robust adhesion, self-healing capabilities, and exceptional mechanical durability alongside superior electrochemical performance, this hydrogel is a promising candidate for high-power-density, long-cycle-lifetime energy storage systems.
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Nano-Micro Letters
·
2026
·Vol. 18
·期 1
·237
·
IF 38.5
Wang Xiaoxue,Xu Yuhui,Zhang Jianhua,Xi Yukun,Hou Ningjing,Chen Yixuan,Liu Dongzhu,Yang Zihao,Wen Haocheng,Kang Jia,Yang Xiaoli,Song Xuexia,Wang Jingjing,Li Wenbin,Zhang Jiujun,Zhang Kun,Li Xifei
Na4Fe3(PO4)2P2O7 (NFPP) is regarded as a prospective cathode for sodium-ion batteries (SIBs) because of its high structural stability and cost-effectiveness. However, its practical application is hindered by intrinsically low electronic conductivity. Herein, an unconventional electron transfer mechanism from Ni2+ to Fe3+ ions is unveiled in Ni-doped Na4.3Fe3(PO4)2P2O7 (NFPP-Ni) cathode, which facilitates electronic coupling within the Fe−O−Ni coordination unit and thereby effectively boosts electron transport. Moreover, the redox kinetics and reversibility of NFPP materials are predominantly governed by the degree of Fe−O covalency. The intermediate eg occupancy of Fe2+, modulated by the presence of Ni2+, optimizes the overlap between Fe d and O p orbitals. The adjustment of Ni dopant strikes a balance between accelerating Na+ diffusion kinetics and mitigating lattice strain during cycling. As a result, the NFPP-Ni electrode displays impressive rate capacity (121.0 mAh g−1 at 0.1C / 80.9 mAh g−1 at 10C) and stable cyclability (89.1% capacity retention after 1000 cycles). More importantly, the relationship between Fe eg orbital occupancy and Fe−O covalency in NFPP as modulated by various transition metal cations (Ni2+, Mn2+, Zn2+, Co2+ and Cu2+) with different electron configurations are systematically elucidated, thereby providing insights for the commercial development of sodium-ion batteries (SIBs).
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JOURNAL OF MATERIALS SCIENCE
·
2026
·
IF 4.4
Cui Wenfang,Zhu Mingzhu,Sun Yongmei,Zhang Keyu,Ma Mei
The three-dimensional framework for lithium storage endows TiP 2 O 7 with excellent stability and considerable capacity. However, its practical application is hindered by poor electrical conductivity and an unclear understanding of its structural evolution. Herein, we present a nitrogen-doped carbon-coated TiP 2 O 7 composite prepared by a straightforward and scalable surface modification strategy, which exhibits superior rate capability compared to previous reports. Specifically, it achieves specific capacities of 435, 341, and 263 mA h g −1 at current densities of 2, 5, and 10 A g −1 , respectively. Kinetic analysis confirms that the nitrogen-doped carbon coating on TiP 2 O 7 surface significantly accelerates the interfacial charge transfer, leading to a dominant pseudocapacitive behavior. Importantly, ex-situ transmission electron microscopy characterization reveals that the TiP 2 O 7 in the composite evolves into homogeneous nanocrystals after 100 cycles at a low current density of 0.2 A g −1 . By contrast, despite the TiP 2 O 7 transforming into nanocrystals with inconsistent sizes and reduced crystallinity after 1000 cycles at a high current density of 1 A g −1 , the effective coating of N-doped carbon preserves the capacity of the anode at up to 462.6 mA h g −1 . These findings suggest that this universal strategy can significantly enhance the performance of TiP 2 O 7 -based anode materials for lithium-ion batteries. Graphical abstract
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International Journal of Minerals Metallurgy and Materials
·
2026
·Vol. 33
·期 2
·657-668
·
IF 8.8
Liu Haobo,Wang Liangtai,Qiao Tongjie,Xi Fengshuo,Chen Xiuhua,Lu Jijun,Li Xiufeng,Ma Wenhui,Li Shaoyuan
The rapid expansion of the photovoltaic industry has generated heavily oxidized waste silicon (wSi), which hinders efficient recycling owing to its small particle size and uncontrolled surface oxidation. This study introduces a molten salt electrochemical strategy for converting photovoltaic wSi into NiSi 2 –silicon nanorods (NiSi 2 –SiNRs) as high-performance anode materials for lithium-ion batteries. A stable oxidized passivation layer is formed on the wSi surface via controlled oxidation, and further in situ generated highly active NiSi 2 droplets. The molten salt electric field modulates the surface energy of silicon, while particle integration drives localized directional growth, enabling the self-assembly of NiSi 2 –SiNRs composites. These NiSi 2 –SiNRs anodes exhibit rapid ion transport and effective strain buffering. The high aspect ratio of SiNRs and the presence of retained NiSi 2 facilitate both longitudinal and transverse Li + diffusion. Owing to their robust structural design, the NiSi 2 –SiNRs anode achieves an excellent initial Coulombic efficiency of 91.61% and retains 72.99% of its capacity after 800 cycles at 2 A·g −1 . This study establishes a model system for investigating silicide/silicon interfaces in molten salt electrochemical synthesis and provides an effective strategy for upcycling photovoltaic wSi into high-performance lithium-ion battery anodes.
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Nature Communications
·
2026
·Vol. 17
·期 1
·987
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IF 15.7
Wei Zhidong,Jin Fei,Li Tong,Qian Lili,Ma Juan,Liu Fengling,Zheng Weiying,Wang Yu,Zhang Siwei,You Ye,Feng Zhang-Qi,Wang Ting
Capacitively coupled electrical stimulation modulates neuronal activity through reversible charging and without charge transfer reactions. This represents a promising and safe neuromodulation scheme but achieving wireless and high capacitive charge density injection remains challenging. Here, we developed a topological fibrous-architecture sonocapacitor (SonoCap) that assembled from piezoelectric-dielectric composite nanosphere (UCapT) and two-dimensional cellulose. UCapT features a unique piezoelectric core-hollow cavity-dielectric cage structure that can efficiently couples ultrasound excitation to achieve piezoelectric electron-capacitance transfer, and its highly assembled SonoCap achieves cumulative charge storage, a high ion-accessible surface area, and macroscopic softness, thereby enabling wireless and high capacitive charge density injection. SonoCap can achieve a capacitive charge density output of up to 9.7 mC cm −2 under 0.63 W cm −2 ultrasound excitation, while generating a negligible Faradaic charge of 2 nC cm −2 . We demonstrated that SonoCap can transcranially and epidurally modulate neural circuit dynamics in rat and pig brains, without introducing intracerebral foreign bodies and maintaining ventricular homeostasis. By integrating a deep learning-based closed-loop diagnostic system, on-demand, wireless, and epidural capacitive electrical stimulation treatment for temporal lobe epilepsy can be achieved. The design concept of SonoCap is expected to inspire expanding development of functional capacitive stimulators, potentially promoting the widespread application of capacitive electrical neuromodulation.
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