CELLULOSE
·
2021
·Vol. 28
·期 17
·10707-10714
·
IF 5.044
Li Hongbing,Zong Yudong,Li Xia,Ding Qijun,Jiang Yifei,Han Wenjia
Cellulose is the most widely distributed polymer material in nature and is considered a low-cost, green and recyclable material. Because of its excellent mechanical, optical and thermal properties, people are interested in the research of cellulose-based flexible electronic devices. Among them, bacterial cellulose has a low fiber bundle size during the production process and is easier to process to obtain nanofibers. Hereby, in this study the composite thermoelectric film was prepared from bacterial cellulose nanofibers (BCNFs) and copper iodide (CuI), a low-toxicity thermoelectric material. Hydrophobic properties of the composite thermoelectric film were obtained by immersing in AKD emulsion. It showed good mechanical flexibility and high biocompatibility. CuI particles can be recovered successfully through cellulase simulating the degradation process, and the closed-loop of preparation-recycling can be completed. In addition, it achieves an open circuit voltage of 11.3 mV and output power of 2.76 nW at a temperature difference of 70 K. This work not only confirms the environmental protection of CuI/BCNF thermoelectric film, but also provides a strategy for the recycling of thermoelectric equipment.
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高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
·
2021
·Vol. 19
·期 1
·1-13
·
IF 10.435
Zhang Yunguang,Sun Si,Liu Haile,Ren Qinjuan,Hao Wenting,Xin Qi,Xu Jiangang,Wang Hao,Zhang Xiao-Dong
Background Neurotrauma is a worldwide public health problem which can be divided into primary and secondary damge. The primary damge is caused by external forces and triggers the overproduction of peroxides and superoxides, leading to long-lasting secondary damage including oxidative stress, wound infection and immunological reactions. The emerging catalysts have shown great potential in the treatment of brain injury and neurogenic inflammation, but are limited to biosafety issues and delivery efficiency.Results Herein, we proposed the noninvasive delivery route to brain trauma by employing highly active gold clusters with enzyme-like activity to achieve the early intervention. The decomposition rate to H2O2 of the ultrasmall gold clusters is 10 times that of glassy carbon (GC) electrodes, indicating excellent catalytic activity. The gold clusters can relieve the oxidative stress and decrease the excessive O2·− and H2O2 both in vitro and in vivo. Besides, gold clusters can accelerate the wound healing of brain trauma and alleviate inflammation via inhibiting the activation of astrocytes and microglia through noninvasive adminstration. decrease the peroxide and superoxide of brain tissue.Conclusion sPresent work shows noninvasive treatment is a promising route for early intervention of brain trauma.
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PubMed
高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
·
2021
·Vol. 19
·期 1
·1-11
·
IF 10.435
Kong Hanjing,Fang Chao,Chu Qiang,Hu Zefeng,Fu Yike,Han Gaorong,Li Xiang,Zhou Yi
Nanoparticles, presenting catalytic activity to induce intracellular oxidative species, have been extensively explored for tumor treatment, but suffer daunting challenges in the limited intracellular H 2 O 2 and thus suppressed therapeutic efficacy. Here in this study, a type of composite nanoparticles, consisting CaO 2 core and Co-ferrocene shell, is designed and synthesized for combinational tumor treatment. The findings indicate that CaO 2 core can be hydrolyzed to produce large amounts of H 2 O 2 and calcium ions at the acidic tumor sites. Meanwhile, Co-ferrocene shell acts as an excellent Fenton catalyst, inducing considerable ROS generation following its reaction with H 2 O 2 . Excessive cellular oxidative stress triggers agitated calcium accumulation in addition to the calcium ions released from the particles. The combined effect of intracellular ROS and calcium overload causes significant tumor inhibition both in vitro and in vivo.
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PubMed
高影响因子
Nature Communications
·
2021
·Vol. 12
·期 1
·1-11
·
IF 14.919
Cui Yan,Huang Zongwang,Lei Li,Li Qinglin,Jiang Jinlong,Zeng Qinghai,Tang Aidong,Yang Huaming,Zhang Yi
Death from acute hemorrhage is a major problem in military conflicts, traffic accidents, and surgical procedures, et al. Achieving rapid effective hemostasis for pre-hospital care is essential to save lives in massive bleeding. An ideal hemostasis material should have those features such as safe, efficient, convenient, economical, which remains challenging and most of them cannot be achieved at the same time. In this work, we report a rapid effective nanoclay-based hemostatic membranes with nanoclay particles incorporate into polyvinylpyrrolidone (PVP) electrospun fibers. The nanoclay electrospun membrane (NEM) with 60 wt% kaolinite (KEM1.5) shows better and faster hemostatic performance in vitro and in vivo with good biocompatibility compared with most other NEMs and clay-based hemostats, benefiting from its enriched hemostatic functional sites, robust fluffy framework, and hydrophilic surface. The robust hemostatic bandages based on nanoclay electrospun membrane is an effective candidate hemostat in practical application.
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PubMed
高影响因子
POLYMER BULLETIN
·
2021
·Vol. 79
·期 9
·7809-7826
·
IF 2.87
Liu Zhaowen,Chen Xiuqiong,Wen Yanshi,Bao Chaoling,Liu Chunyang,Cao Shirui,Yan Huiqiong,Lin Qiang
To improve the affinity of alginate to the hydrophobic drug molecules, such as ibuprofen, the Ugi four-component condensation reaction involving sodium alginate (SA), tosylmethyl isocyanide, propionaldehyde and octylamine was proposed to synthesize the novel amphiphilic alginate-bisamide derivative (AABD) without any organic solvents and catalysts. The molecular structure and self-aggregate behavior of the resultant AABD was characterized by FT-IR spectrometer, 1 H NMR spectrometer, X-ray diffraction, thermal gravimetric analysis, fluorescence spectrophotometer, transmission electron microscope and dynamic light scattering. Meanwhile, the loading and in vitro release of ibuprofen for the AABD microcapsules prepared by the emulsification method as well as their cytotoxicity were also investigated. Experimental results showed that the AABD with the degree of substitution of 19.41% was successfully prepared by the Ugi reaction, and the grafting of hydrophobic side groups on the backbone of alginate was conducive to enhancing its molecular flexibility and colloidal interface activity. Therefore, the AABD could reveal good amphiphilic property with the critical aggregation concentration (CAC) of 0.105 g/L in 0.15 mol/L aqueous NaCl solution, and form the self-aggregated micelle with the average hydrodynamic diameter of 396 nm (PDI = 0.31) and zeta potential at about − 62.4 mV. Furthermore, the prepared AABD microcapsules displayed the high encapsulation efficiency and sustained-release property in comparison with the SA microcapsules for the good affinity of AABD to hydrophobic ibuprofen that retarded the drug diffusion. And it also exhibited low cytotoxicity to the murine macrophage RAW264.7 cells. Therefore, the novel amphiphilic AABD synthesized by the Ugi reaction would be of great potentials as the hydrophobic drug carriers for sustained-release formulations.
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高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2021
·Vol. 413
·期 28
·6941-6949
·
IF 4.157
Gu Chunchuan,Chen Xiang,Liu Hongying
In this report, portable, quantitative, and sequential monitoring of copper ions and pyrophosphate (PPi) with a single sensor based on a DNAzyme-Fe 3 O 4 system and glucometer readout was performed. Initially, streptavidin was functionalized on the surface of magnetic Fe 3 O 4 spheres through glutaraldehyde. Then, an invertase-modified DNA Cu substrate was connected to the magnetic Fe 3 O 4 spheres by a specific reaction between streptavidin and biotin. The sensing system was formed by a hybridization reaction between the Cu substrate and Cu enzyme. In the presence of Cu 2+ , Cu 2+ will recognize the Cu DNA substrate and form an “off-on” signal switch, thereby resulting in the separation of invertase from the Fe 3 O 4 nanospheres. PPi recognizes Cu 2+ to form a Cu 2+ -PPi complex, resulting in an “on-off” signal switch. Under optimized conditions, linear detection ranges for Cu 2+ and PPi of 0.01–5 and 0.5–10 μM, and detection limits for Cu 2+ and PPi of 10 nM and 500 nM, respectively, were obtained. Good selectivity was achieved for the analysis of Cu 2+ and PPi. Satisfactory results were achieved for this biosensor during the determination of Cu 2+ in real tap samples and PPi in human urine samples. This verified that the sensor is portable and low cost, and can be applied to the sequential monitoring of multiple analytes with a single point-of-care biosensor. Graphical abstract
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 5
·3211-3221
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IF 4.682
Qin Bihui,Li Yan,Kang Hongfei,Huang Suping,Xiao Qi
Monolithic carbon nanofiber aerogels (MCNAs) have aroused much attention for their unique properties. At present, oil pollution has posed great threats to the environment. MCNAs are supposed to be suitable adsorbents for oil adsorption owing to their porous structure, low density and ease of handling. However, facile and inexpensive synthesis of MCNAs still remains a challenge. On this account, low-cost minerals are found to be ideal templates for carbon synthesis. Chrysotile nanofibers with natural fibrous structure were applied as template for MCNAs preparation in this work. Furthermore, calcination at different temperatures was employed to regulate the pore structures and hydrophobicity to enhance oil adsorption capacity. Meanwhile, chrysotile would decompose and form Mg-silicates (MS) under high temperature. MCNAs obtained from this method exhibited a three-dimension cross-linked network structure and good hydrophobicity, leading to high oil adsorption capacity ranged from 25.9 to 29.1 g g −1 . Furthermore, the relationship of oil adsorption capacity with mesopore surface area and contact angle was discussed. The work provides not only a novel pathway for low-cost and environmental synthesis of MCNAs, but also a solution for optimizing the performance of oil adsorbents. Graphical abstract
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 4
·2909-2923
·
IF 4.682
Zeng Sen,Hou Yaqi,Zhou Yaming,Zhou Xi,Ye Shefang,Wang Miao,Ren Lei
Protein-bound uremic toxins (PBUTs) are difficult to remove through dialytic procedures, and the accumulation of PBUTs is always associated with adverse symptoms in end-stage kidney disease. Hemoperfusions and novel membranes have been developed for the removal of PBUTs, but still suffer from low efficiency. Herein, we investigated the adsorption performance of three zirconium metal–organic frameworks (Zr-MOFs: UiO-66, UiO-66-SO 3 H, and UiO-66-(COOH) 2 ) for two typical PBUTs (indoxyl sulfate, IS; hippuric acid, HA). We found that Zr-MOFs could adsorb PBUTs efficiently with a capacity of as high as 49.5 mg g −1 for IS and 38.3 mg g −1 for HA, respectively, due to the van der Waals interactions, Coulomb interactions, and π – π interactions. Density functional theory simulations demonstrated that H-bonding on basis of the –SO 3 H and –COOH groups could endow MOFs with better absorptivity. Further, to expand to practical hemodialysis applications, we incorporated Zr-MOFs into a polylactide (PLA) matrix to fabricate MOFs-based mixed matrix membranes (MMMs). The MMMs showed excellent in vitro biocompatibility and high water flux up to 260 L m −2 h −1 . Under static conditions, the MMMs could remove HA and IS with a percentage of 75 and 78% in 4 h, respectively, whereas PLA membrane removed 12% of HA and 13% of IS. Under dynamic conditions, MMMs could remove 57% of IS and 54% of HA in 30 min; by contrast, PLA membrane only removed 2.9% of IS and 2.2% of HA. These MOFs-based MMMs with exceptional absorptivity, high water flux, and good biocompatibility might show great prospects in the foreground for the application of safe and efficient blood purification.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 1
·598-617
·
IF 4.682
Meng Minjia,Zheng Jian,Cui Yanhua,Li Binrong,Yang Lili,Zhu Yu,Li Chunxiang
The weak light absorption capacity and the embedding of active sites are the main factors that affect the photodegradation performance of blending photocatalytic membrane. Herein, a Z-scheme TiO 2 /rGO/ZnCdS/PVDF photocatalytic composite membrane (T-rGO-ZCSM) with excellent mechanical properties and good self-cleaning performance was successfully prepared by the freezing phase inversion method. As the solvent turns to crystal under freezing temperature, the micron-scale ordered penetrating porous structure formed after phase inversion, which can efficiently improve the water flux (19000–25000 L m −2 h −1 bar −1 ) and light penetration. Meanwhile, Z-scheme TiO 2 /rGO/ZnCdS heterojunctions will be migrated to the surface of the large pore canal due to their hydrophilicity during the phase inversion process. This structure can promote light absorption and increase effectively contact between active sites and pollutants. The T-rGO-ZCSM also exhibits outstanding photocatalytic activity for removing the various antibiotics under visible light, such as tetracycline (TC), levofloxacin (LEV), and ciprofloxacin (CIP). After four cycles (1.0 h for each cycle) of experiments, T-rGO-ZCSM has good stability and reusability. Moreover, the TC degradation efficiency of T-rGO-ZCSM reached the highest of 87.46% under continuous 6.0 h solar irradiation. The superoxide radical (·O 2 − ) and photogenerated h + were the main active species for organics’ degradation. In summary, the ordered penetrating type macroporous T-rGO-ZCSM has promising potentials for wider applications in wastewater treatment. Graphical Abstract
A hierarchical-ordered penetrating-type porous T-rGO-ZCSM membrane was prepared by freezing phase inversion method. The membrane surface with large pore diameters can provide a more convenient transport pathway, and pollutants can be transferred to the active sites to increase effective contact. It can also enhance the visible light absorption to excite more photogenerated carriers and improve photocatalytic activity. Finally, the photocatalytic degradation efficiency of freezing T-rGO-ZCSM could be increased by 1.71 times compared to that of the conventional blending nf-T-rGO-ZCSM under visible light.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 2
·1036-1043
·
IF 4.682
Chen Xue-Qiang,Xie Lina,Cao Ming,Hu Wenjing,Gong Lifei,Fang Shiqiang
Inspired by inorganic oligomers, we herein develop a novel inorganic gel based on calcium oxalate oligomers, and the crystallization morphology has been studied initially in this paper. The prepared oligomer is translucent gel and can exist stably in ethanol, but in aqueous medium it will change from gel to powder. In the crystallization process, because of the volatile speed of solvent and capping agent TEA at different temperature, CaC 2 O 4 oligomer gels (COOGs) exhibited distinct crystallization behavior and morphology. Compared with conventional inorganic crystallization, the crystallization process of the gel at room temperature shows a tendency to gradually extend to the inside of the gel. Moreover, the XRD pattern and SEM images shown that the COOGs achieved distinctly different crystal morphology under different temperature. These provide a preliminary research foundation for the crystallization behavior and control conditions of inorganic gels. Graphical abstract
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高影响因子
JOURNAL OF ELECTRONIC MATERIALS
·
2022
·Vol. 51
·期 3
·1128-1136
·
IF 2.047
He Yi,Li Ying,Yuan Ying,Shu Jun,Deng Xiaoyan,Li Lu
Wearable pressure sensors with an ultra-wide linearity range and high sensitivity have atttracted increasing interest on account of their great potential applications in artificial tactile sensing, human health monitoring and care systems. Herein, poly(3,4-ethylenedioxythiophene) (PEDOT) was in situ synthesized on non-woven fabric and served as the sensing layer to realize highly reliable wearable all-fabric pressure sensors. Because of the surface microstructure of the PEDOT-coated fabric, such pressure sensors exhibited excellent performance, which included a high sensitivity of 5.95 kPa -1 , wide working range (0-200 kPa) and fast response/recovery time (11/15 ms). Their practical applications in human physiological signal monitoring are further demonstrated, showing their potential as wearable electronics in health monitoring.
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高影响因子
JOURNAL OF POLYMER RESEARCH
·
2021
·Vol. 29
·期 1
·1-15
·
IF 3.097
He Tingxiang,Guo Junhong,Qi Chengxia,feng Rui,Yang Baoping,Zhou Yingping,Tian Li,Cui Jinfeng
Phosphorus-containing organic–inorganic hybrid flame retardant with core–shell structure (Salen-PZN-Cu@Ni-Mof) was prepared. Thermogravimetric analysis (TGA) showed that when the additive amount was only 3wt%, the introduction of Salen-PZN-Cu@Ni-Mof significantly improved the thermal stability of epoxy resin (EP) composites. The results of the cone calorimeter test showed that adding 3wt% Salen-PZN-Cu@Ni-Mof made the peak of heat release rate (PHRR), total heat release (THR), smoke production rate (SPR) and total smoke production (TSP) of epoxy resin composites reduced by 30.4%, 10.8%, 29.5% and 6.8%, respectively. It was proved that Salen-PZN-Cu@Ni-Mof could significantly enhance the fire safety of epoxy resin composites, which was attributed to the synergetic combination of the flame retardant effect of the phosphazene structure itself, the catalyzed carbon formation of various metal ions and the porous mof materials with strong adsorption properties. Besides, it was found that the Ni-Mof could strengthen the compatibility between the flame retardant and the EP matrix effectively through the tensile test. The novel core–shell structure flame retardant Salen-PZN-Cu@Ni-Mof promised to be a functional filler that integrated features of flame retardancy and high ductility.
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高影响因子
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