CHEMICAL ENGINEERING JOURNAL
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2023
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IF 15.1
Yuhong Cui,Baoluo He,Shenghua Xue,Zhuo Chen,Shujuan Liu,Qian Ye,Feng Zhou,Weimin Liu
Improving the tribological performance of water via designing nanomaterials as lubricant additive has garnered mounting interest. In this work, the poly-(N-isopropylacrylamide) microgel is grafted onto Fe 3 O 4 nanoparticles surface (Fe 3 O 4 @PNA) via free radical polymerization. Then, the Fe 3 O 4 @PNA can self-anchored on the MXene nanosheets via hydrogen bonding interaction to obtain MXene@Fe 3 O 4 @PNA composite. The as-prepared MXene@Fe 3 O 4 @PNA can effectively reduce friction and wear when used as a water-based lubricant additive. Compared with pure water, the average coefficient of friction (COF) and wear volume decrease by 61% and 78.7%, respectively. The lubrication mechanism was analyzed by focused ion beam technique-TEM (FIB-TEM) and X-ray photoelectron spectroscopy (XPS). The outstanding tribological performance of MXene@Fe 3 O 4 @PNA is attributed to the synergistic lubrication effect of MXene and Fe 3 O 4 @PNA. Interlayer shear of MXene and spherical Fe 3 O 4 @PNA can make MXene@Fe 3 O 4 @PNA play a full role of sliding friction and rolling friction mechanism, which can induce tribo-chemical reactions to form a protective film on the contact area of the friction pair. In addition, the hydrophilic groups of the MXene@Fe 3 O 4 @PNA can adsorb a large number of water molecules and form a hydration layer, reducing the agglomeration of nanosheets and acting as a boundary lubrication film. Moreover, the as-prepared MXene@Fe 3 O 4 @PNA exhibit excellent photothermal conversion performance in both underwater environment and dry state. Based on this characteristic, infrared light can be collected efficiently and stored quickly. Then, convert and utilize it. Therefore, the multifunctional MXene@Fe 3 O 4 @PNA has a broad application prospect as a water-based intelligent lubrication additive.
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Foods
·
2023
·Vol. 12
·期 10
·2011
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IF 5.2
Lilai Mo,Xinzhuan Yao,Hu Tang,Yan Li,Yujie Jiao,Yumei He,Yihe Jiang,Shiyu Tian,Litang Lu
Cuticular wax is a complex mixture of very long-chain fatty acids (VLCFAs) and their derivatives that constitute a natural barrier against biotic and abiotic stresses on the aerial surface of terrestrial plants. In tea plants, leaf cuticular wax also contributes to the unique flavor and quality of tea products. However, the mechanism of wax formation in tea cuticles is still unclear. The cuticular wax content of 108 germplasms (Niaowang species) was investigated in this study. The transcriptome analysis of germplasms with high, medium, and low cuticular wax content revealed that the expression levels ofCsKCS3andCsKCS18were strongly associated with the high content of cuticular wax in leaves. Hence, silencingCsKCS3andCsKCS18using virus-induced gene silencing (VIGS) inhibited the synthesis of cuticular wax and caffeine in tea leaves, indicating that expression of these genes is necessary for the synthesis of cuticular wax in tea leaves. The findings contribute to a better understanding of the molecular mechanism of cuticular wax formation in tea leaves. The study also revealed new candidate target genes for further improving tea quality and flavor and cultivating high-stress-resistant tea germplasms.Keywords:cuticle wax;KCSgene family;tea plant (Camellia sinensis);wax biosynthesis
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PHYTOMEDICINE
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2023
·
IF 7.9
Zhihui Cai,Jinjin He,Jun Jiang,Zihan Zhao,Ye Shu
Background Sepsis is one of the major threats to human health with high mortality. Simiao Yong'an decoction (SMYAD) has the efficacy of anti-inflammation, improving coagulation and microcirculation, which is applicable for the clinical assistance treatment of sepsis . Yet, its material basis and relevant mechanisms are still vague. Purpose Explore the quality markers (Q-markers), biomarkers and potential mechanisms of SMYAD combined with imipenem/cilastatin sodium for anti-sepsis. Methods Linear-Trap-LC/MS n was employed to profile the compounds in the extract and medicated serum of SMYAD. Then, the components and targets obtained from databases were applied to network pharmacology. Q-markers’ range was narrowed via the affinity of three times docking and determined as per its screening criteria. Also, the content of them was detected by HPLC. Next, cecal ligation and puncture (CLP) model was reproduced to observe the effect of SMYAD united antibiotic by survival rate, histopathology score, ELISA, western blot and qPCR. Finally, metabolomics based upon GC–MS was exerted to discover the differential endogenous metabolites, metabolic pathway and joint pathway of SMYAD combined with antibiotic for sepsis. Results The 25 serum migrant ingredients derived from 113 chemical compounds of SMYAD were identified for the first time, and 6 components were determined as the Q-markers of SMYAD. The enrichment analysis indicated that the potential mechanism was mainly associated with the IL-17 signaling pathway, complement-coagulation cascades signaling pathway and VEGF signaling pathway. Then, SMYAD united antibiotic declined the mortality of septic rats, restored cytokine levels, ameliorated histopathological lesions and decreased the mRNA and protein expression of target proteins in a dose-dependent way. Furthermore, 8 differential metabolites were regarded as latent biomarkers related to the antiseptic effect of SMYAD united antibiotic, which were mainly involved in the Citrate cycle (TCA cycle) metabolic pathway. Conclusions Different skeletons of compounds, including iridoids, phenylpropanoids, organic acids, triterpenes and others, were the main compositions of SMYAD. Among them, 6 components were determined as the Q-markers, which provided a basis for the construction of quality standards for this ancient classic formula. The combination therapy of SMYAD and antibiotic obviously ameliorated inflammatory reaction, coagulation dysfunction and microcirculation abnormalities for sepsis by inhibiting IL-17 signaling pathway, complement-coagulation cascades signaling pathway and VEGF signaling pathway.
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CATALYSIS COMMUNICATIONS
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2023
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IF 3.7
Dan Luo,Qin Wang,Jiansu Ran,Ruixue Yangcheng,Yuntong Cui,Shuang Luo,Jianjian Wang
A series of Zr-based catalysts were prepared using various commercial and cheap organic acids as the coordination agents, and these as-synthesized samples exhibited superior activities to produce lactic acid (LaA) from carbohydrates. Using humic acid (HA) as a typical coordination agent, LaA yield was up to 76% over the resultant Zr-HA, outperforming the most recent reported works. Deeper studies revealed that Zr-HA possessed both acid sites and base sites, and these dual active sites can simultaneously activate xylose, resulting in high yield production of LaA. Besides, Zr-HA also showed excellent reusability and can be reused at least five times.
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International Journal of Electrochemical Science
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2023
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IF 1.5
Yinze Zuo,Liang Chen,Yu Wang,Yunxia Guo,Xingling Shi,Yanmin Gao
Pre-processing of a metal surface before coating is a key factor that affects the coating performance. This phenomenon has been puzzling people for a long time. In this paper, a new type of preprocessing using heterocyclic compounds, pyridine and furan, were applied to address this problem. The tests show that the rust layers of mild steel treated by pyridine and furan are more compact than the untreated layers. The corrosion rate of the mild steel with a rust layer treated by pyridine is lower than that of the samples with furan treatment and without treatment, while the impedance is also the largest. The adhesion of an epoxy-polyvinylbutyral (EP-PVB) coating, which is painted on rust layers with pyridine and furan pretreatment, is much stronger. Moreover, the corrosion resistance of EP-PVB coatings that are painted onto the rust layers with pretreatment is much better than that of the coatings that are directly painted onto the rust layer without pretreatment. The impedance of EP-PVB coatings that are painted onto the rust layers with pretreatment is much higher than that of the EP-PVB coating that is directly painted onto the rust layer without pretreatment.
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International Journal of Electrochemical Science
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2023
·
IF 1.5
Hu Wang,Jun Tang,Juan Xie
Corrosion inhibition effects of asymmetric gemini corrosion inhibitor on N80 steel in a CO 2 -saturated brine solution had been investigated by weight loss and electrochemical measurements. The synergistic effects of gemini with thiourea (TU), thiazole (TZ) and pyridine (PD) were also studied with weight loss and electrochemical measurements. The results revealed that asymmetric gemini corrosion inhibitor displayed excellent corrosion inhibition performance at 70°C in CO 2 -saturated brine solution. The inhibitor was anodic type in nature. There existed apparent synergistic effect between asymmetric gemini inhibitor and other ingredients. The mixture inhibitors can provide excellent protection to N80 steel at test condition. The best formula of mixture inhibitors was then presented. The synergistic mechanism of gemini with other ingredients were also discussed.
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Natural Products and Bioprospecting
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2023
·Vol. 13
·期 1
·1-9
·
IF 4.7
Wen Luan,Wu Zhou-Wei,Lin Li-Wu,Al-Romaima Abdulbaset,Peng Xing-Rong,Qiu Ming-Hua
Four polysaccharides (MCPa, MCPb, MCPc, MCPd) were obtained from Lepidium meyenii Walp. Their structures were characterized by chemical and instrumental methods including total sugar, uronic acid and protein content determination, UV, IR and NMR spectroscopy, as well as monosaccharide composition determination and methylation analyses. Four polysaccharides were a group of glucans with different molecular weights ranging from 3.12 to 14.4 kDa, and shared a similar backbone chain consisting of (1→4)-glucose linkages with branches attached to C-3 and C-6. Furthermore, bioactivity assay showed that MCPs had concentration-dependent inhibitory activity on α -glucosidase. MCPb (Mw = 10.1 kDa) and MCPc (Mw = 5.62 kDa) with moderate molecular weights exhibited higher inhibitory activity compared with MCPa and MCPd. Graphical Abstract
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CHEMOSPHERE
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2023
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IF 8.8
Falin He,Tianyu Qi,Shuqi Guo,Hao Wang,Zhuo Zhang,Rutao Liu,Wansong Zong
Pyridine and its derivatives are widely used in many applications and inevitably cause extreme scenarios of serious soil contamination, which pose a threat to soil organisms. Still, the eco-toxicological effects and underlying mechanisms of pyridine-caused toxicity toward soil fauna have not been well established. Thus, earthworms ( Eisenia fetida ), coelomocytes, and oxidative stress-related proteins were selected as targeted receptors to probe the ecotoxicity mechanism of extreme pyridine soil exposure targeted to earthworms by using a combination of in vivo animal experiments, cell-based in vitro tests, in vitro functional and conformational analyses, and in silico analyses. The results showed that pyridine caused severe toxicity to E. fetida at extreme environmental concentrations. Exposure of pyridine induced excessive ROS formation in earthworms, causing oxidative stress and various deleterious effects, including lipid damage, DNA injury, histopathological change, and decreased defense capacity. Also, pyridine destroyed the cell membrane of earthworm coelomic cells and triggered a significant cytotoxicity. Importantly, the intracellular ROS (e.g., O 2 − , H 2 O 2 , and OH· – ) was release-activated, which eventually inducing oxidative stress effects (lipid peroxidation, inhibited defense capacity, and genotoxicity) through the ROS-mediated mitochondrial pathway. Moreover, the antioxidant defence mechanisms in coelomocytes responded quickly to reduce ROS-mediated oxidative injury. It was conformed that the abnormal expression of targeted genes associated with oxidative stress in coelomic cells was activated after pyridine exposure. Particularly, we found that the normal conformation (particle sizes, intrinsic fluorescence, and polypeptide backbone structure) of CAT/SOD was destroyed by the direct binding of pyridine. Furthermore, pyridine bound easily to the active center of CAT , but preferentially to the junction cavity of two subunits of SOD, which is considered to be a reason for impaired protein function in cells and in vitro. Based on these evidences, the ecotoxicity mechanisms of pyridine toward soil fauna are elucidated based on multi-level evaluation.
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JOURNAL OF CATALYSIS
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2023
·
IF 7.3
Yuexia Wang,Qibin Yao,Bowen Xu,Kehang Lin,Mengshan Deng,Xinqing Lu,Rui Ma,Yanghe Fu,Weidong Zhu
Although the oxidative hydration of ethylene with hydrogen peroxide (H 2 O 2 ) to ethylene glycol (EG) over Ti-MWW zeolites take advantages of step-saving and facile operation, both H 2 O 2 utilization efficiency and EG yield are relatively low, because some extra-framework octahedral Ti species are usually formed in the Ti-MWW zeolites synthesized by prevailing methods, which are detrimental to selective oxidation . In the present work, an acid-modulated isomorphous substitution method, i.e. , layered borosilicate MWW-type zeolite (ERB-1) treated with HNO 3 aqueous solution containing tetrabutyl orthotitanate (TBOT), is developed to synthesize a Ti-MWW zeolite without extra-framework octahedral Ti species under the optimized synthesis conditions. In combination with the results from extensive characterizations for the synthesized zeolites, it is found that in the zeolite prepared by the currently developed synthesis method there are more open Ti(OSi) 3 OH sites formed, resulting in the stronger Lewis acidity that is very helpful to EG production from the oxidative hydration of ethylene with H 2 O 2 , compared to the one synthesized by the prevailing method. Moreover, the developed catalyst is recyclable after the regeneration of the deactivated zeolite by calcination at high temperatures. Therefore, it is anticipated that the currently developed Ti-MWW might be industrially applicable in the one-pot synthesis of EG from ethylene with H 2 O 2 .
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EUROPEAN POLYMER JOURNAL
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2023
·
IF 6
Gaojie Wu,Shengli Qi,Guofeng Tian,Dezhen Wu
In order to solve the challenge of balancing the thermoplastic processing properties and thermal dimensional stability of polyimide (PI) resin, in this research, 3,3′,4,4′-biphenyl tetracarboxylic diandhydride (BPDA) and 2,2′-bis(trifluoromethyl)benzidine (TFMB) were used as rigid components, 4,4′-oxydiphthalic anhydride (ODPA) and 4,4′-diaminodiphenyl sulfone (DDS) as flexible components. A series of random copolyimide resins was prepared by adjusting the molar ratio of rigid and flexible monomers. Determining the molar ratio which could balance the thermoplastic processing properties and thermal dimensional stability, block copolyimide resins with different rigid and flexible block lengths were then prepared in this ratio. The research showed that the molar ratio of monomers and the sequence structure of molecular chains had a strong influence on the performance of PI resins. When the content or block length of rigid component increased, the coefficient of thermal expansion (CTE) decreased but the glass transition temperatures ( T g ) and melt viscosity increased. The PI-B343 resin had a CTE value of 40.63 ppm/K and the lowest melt viscosity reached 675 Pa·s, achieved the simultaneous regulation of the thermoplastic processing properties and thermal dimensional stability for PI resin.
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CARBOHYDRATE POLYMERS
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2023
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IF 11.2
Xiaoli Tang,Zhuqun Wang,Maosen Wang,Shuyu Zhou,Jinghua Chen,Shuqin Xu
Demyelination is a serious complication of neurological disorders, which can be reversed by oligodendrocyte precursor cell (OPC) as the available source of myelination . Chondroitin sulfate (CS) plays key roles in neurological disorders, which still attracted less attention on how CS modulates the fate of OPCs . Nanoparticle coupled with glycoprobe is a potential strategy for investigating the carbohydrate-protein interaction. However, there is lack of CS-based glycoprobe with enough chain length that interact with protein effectively. Herein, we designed a responsive delivery system, in which CS was the target molecule, and cellulose nanocrystal (CNC) was the penetrative nanocarrier . A coumarin derivative (B) was conjugated at the reducing end of an unanimal-sourced chondroitin tetrasaccharide (4mer). This glycoprobe (4B) was grafted to the surface of a rod-like nanocarrier, which had a crystalline core and a poly(ethylene glycol) shell. This glycosylated nanoparticle (N4B-P) displayed a uniform size, improved water-solubility, and responsive release of glycoprobe. N4B-P displayed strong green fluorescence and good cell-compatibility, which imaged well the neural cells including astrocytes and OPCs. Interestingly, both of glycoprobe and N4B-P were internalized selectively by OPCs when they were incubated in astrocytes/OPCs mixtures. This rod-like nanoparticle would be a potential probe for studying carbohydrate-protein interaction in OPCs.
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Antibiotics-Basel
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2023
·Vol. 12
·期 3
·591
·
IF 4.8
Changhai Liu,Feng Cheng,Haji Akber Aisa,Maitinuer Maiwulanjiang
Carum carviL. belongs to theApiaceaefamily and is widely used as a vegetable, food spice, preservative, and herbal medicine. This study investigated the impact of essential oil extracted fromCarum carviL. seeds (CEO) on methicillin-resistantStaphylococcus aureus(MRSA) and its possible action mechanism. The dominant chemical components of CEO determined by GC-MS were carvone and limonene. It was observed that CEO had a considerable inhibitory effect against the growth of planktonic bacteria and biofilm in MRSA cells. Untargeted metabolomics based on GC-Q-TOF-MS was used to analyze the possible mechanism of the interaction of MRSA with CEO. It was determined that there were 63 different metabolites based on fold change values greater than 1.5 or less than 1.5,p< 0.05, VIP > 1, which demonstrated amino acid metabolism in MRSA was significantly affected by CEO. In conclusion, CEO has a potent antimicrobial property and has promising potential for use in food and drugs.Keywords:Carum carviL.;essential oil;MRSA;GC-Q-TOF-MS;metabolomics
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