MICROCHIMICA ACTA
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2019
·Vol. 186
·期 2
·1-10
·
IF 5.479
Zhang Kaina,Hu Dehua,Deng Suimin,Han Meng,Wang Xiangfeng,Liu Hailing,Liu Yuan,Xie Mengxia
A novel magnetic nanomaterial for use in metal ion based affinity chromatography is described. It is based on the chelation between the phosphate groups of phytic acid (PA) and Ti(IV) ions. Due to the large number (6) of phosphate groups of PA, it has a large capacity for Ti(IV) ions. PA was first immobilized on magnetite nanoparticles (PA-MNPs) and then loaded with Ti(IV) ions to obtain the sorbent (Ti-PA-MNPs). The fraction of Ti(IV) ions on the surface of PA-MNPs that is exposed to the solution binds the phosphate groups of phosphopeptides. The bound phosphopeptides can then be magnetically separated. The method was applied to the enrichment of the phosphopeptides in a β-casein tryptic digest. A tryptic digest of bovine serum albumin (BSA) was added at a molar ratio (β-casein to BSA) of 1:2000 to study selectivity. The phosphopeptides were quantified by mass spectrometry. The limit of detection can be as low as 8 × 10 −10 mol L −1 . This sorbent has a high absorption capacity (53.5 μg mg -1 ) and shows good recoveries (90%). As many as 2145 phosphopeptides were isolated from 500 μg tryptic digest of a rat liver lysate after enrichment by Ti-PA-MNPs. This is superior to that (1568 phosphopeptides) of commercial TiO 2 kit.
Schematic presentation of fabrication for a novel modified magnetic nanomaterial (Ti-PA-MNPs) based on the chelation of phytic acid (PA) with Ti(IV) ions. Ti-PA-MNPs were successfully applied to enriching low abundance phosphopeptides from biosamples in mass spectrometric analysis.
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APPLIED SURFACE SCIENCE
·
2019
·
IF 5.155
Li Liu,Qiuyue Yang,Lei Huang,Xiangmei Liu,Yanqin Liang,Zhenduo Cui,Xianjin Yang,Shengli Zhu,Zhaoyang Li,Yufeng Zheng,Kelvin Wai Kwok Yeung,Shuilin Wu
In this work, a conversion coating of phytic acid (PA)/calcium ion (Ca 2+ ) was prepared on a magnesium-strontium (Mg-Sr) alloy surface through a layer-by-layer self-assembly method. The effect of the pH value on the corrosion resistance of coatings was studied systematically. The addition of a Ca 2+ could enhance the intermolecular chelation of PA and repair the defects of the coating itself. The results of electrochemical and immersion testing confirmed that a PA/Ca 2+ conversion coating could adjust the corrosion rate of Mg-Sr alloys. Compared to a bare Mg-Sr alloy, the corrosion current density of Mg&OH&PA(5.5)&Ca 2+ was decreased by about three orders (2.726 × 10 −4 A/cm 2 to 4.304 × 10 −7 A/cm 2 ). In vitro tests showed that a Ca 2+ in the coatings could not only promote the formation of apatite , but also favored osteoblast proliferation. In addition, this conversion coating could significantly enhance the expression of alkaline phosphatase activity by 50–60% compared to a bare Mg-Sr alloy.
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Journal of Materials Chemistry A
·
2019
·Vol. 7
·期 16
·9673-9679
·
IF 10.733
Peng Mu,Wei Bai,Yukang Fan,Zheng Zhang,Hanxue Sun,Zhaoqi Zhu,Weidong Liang,An Li
Solar steam generation by heat localization has attracted much attention for its potential in the treatment of wastewater and seawater desalination. However, the preparation of a single-component solar receiver with low cost, simple preparation process, high mechanical strength and energy conversion efficiency is still a challenge. Herein, we report the preparation of kapok fiber-PPy aerogels with superwetting, porous structure, high light absorption, and high mechanical strength via polypyrrole modification of the Ca2+ crosslinked kapok fiber aerogels. The kapok fiber-PPy aerogels show three-dimensional structure with high porosity (94%), excellent light absorption (ca. 97%), low thermal conductivity (0.0241 W m−1 k−1) and high mechanical strength (0.12 MPa under 75% of strain). As a solar steam generation device, a high energy conversion efficiency of 82.4% was achieved under 1 kW m−2 illumination. The findings of this investigation may open a simple and novel route towards the fabrication of a low-cost a single-component biomass-based solar receivers for solar steam generation.
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INTERNATIONAL JOURNAL OF PHARMACEUTICS
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2019
·
IF 4.213
Xingqi Wang,Yong Zhang,Jie Huang,Mengqiu Xia,Liu Liu,Chunling Tian,Rongfeng Hu,Shuangying Gui,Xiaoqin Chu
The aim of this paper was to develop hexagonal liquid crystalline (H II ) gels that can be used as a novel ocular delivery system for pilocarpine nitrate (PN). H II gels were prepared by a vortex method using phytantriol/triglyceride/water (71.15: 3.85: 26, w/w) ternary system. The gels were characterized by crossed polarized light microscopy, small-angle X-ray scattering, differential scanning calorimetry and rheology. And, in vitro drug release behavior and ex vivo corneal permeation were investigated. Finally, preocular residence time evaluation, eye irritation test, histological examination and miotic tests were studied in vivo and compared with carbopol gel. Based on various characterization techniques, the inner structure of the gels were H II mesophase and exhibited a pseudoplastic fluid behaviour. In vitro release results revealed that PN could be released continuously from H II gel over a period of 24 h. The ex vivo apparent permeability coefficient of H II gel was 3.15-fold (P < 0.01) higher than that of the Carbopol gel. Compared with Carbopol gel, H II gel displayed longer residence time on the eyeballs surface using fluorescent labeling technology. Furthermore, the H II gel caused no ocular irritation was estimated by corneal hydration levels, Draize test and histological inspection. Additionally, in vivo miotic study showed that H II gel had a remarkably long-lasting decrease in the pupil diameter of rabbits. In conclusion, H II gels would be a promising sustained-release formulation for ocular drug delivery.
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TALANTA
·
2019
·
IF 4.916
Yayun Hong,Qiliang Zhan,Yu Zheng,Chenlu Pu,Hongli Zhao,Minbo Lan
In this work, magnetic mesoporous silica microspheres (Mag-MSMs) with ordered radial mesochannels were fabricated by a self-assembly synthesis in chlorobenzene-water mixed system. Then, the obtained Mag-MSMs were modified with polyethyleneimine (PEI), phytic acid (PA) and Ti 4+ (denoted as Mag-MSMs@PEI-PA-Ti 4+ ) via layer by layer (LbL) assembly. Due to the excellent hydrophilicity of PEI and PA and the large amount of Ti 4+ , the Mag-MSMs@PEI-PA-Ti 4+ possessed combined properties of hydrophilic interaction liquid chromatography (HILIC)- and immobilized metal ion affinity chromatography (IMAC)-based materials, which could be used as a dual-purpose material for N-glycopeptides or phosphopeptides enrichment. The proposed Mag-MSMs@PEI-PA-Ti 4+ exhibited an outstanding performance for N-glycopeptides enrichment (selectivity: IgG/BSA = 1:1000; sensitivity: 0.5 fmol/μL IgG) and phosphopeptides enrichment (selectivity: α-casein/BSA=1:5000; sensitivity: 0.2 fmol/μL α-casein). Furthermore, after enrichment with Mag-MSMs@PEI-PA-Ti 4+ , a total of 276 N-glycopeptides assigned to 132 glycoproteins were identified from 2 μL human serum and 1645 phosphopeptides corresponding to 704 phosphoproteins were identified from 200 μg HeLa cell extracts.
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APPLIED SURFACE SCIENCE
·
2019
·
IF 5.155
Wenwen Tian,Dekang Cheng,Shan Wang,Chuanxi Xiong,Quanling Yang
Incorporating manganese dioxide (MnO 2 ) with reduced oxide graphene (RGO) holds great potential as favourable supercapacitor electrodes for energy storage applications. In order to improve the adhesive strength and stability, we synthesized a phytic acid (PA)-linked MnO 2 /RGO aerogel (MnO 2 /P-RGO) through a simple self-assembled hydrothermal and freeze-drying method. Herein, PA as a bridge could accelerate the firm immobilization of MnO 2 on RGO sheets to synthesize the composite aerogel with a three-dimensional (3D) layered porous structure. The 3D MnO 2 /P-RGO composite aerogel as a supercapacitor electrode could achieve the high specific capacitance of 645 F g −1 under the current density of 1 A g −1 and 410 F g −1 at 40 A g −1 . Furthermore, the composite aerogel exhibits remarkable long-term stability, 94.9% of the initial capacitance after 10,000 cycles under the high current density of 20 A g −1 . Moreover, the assembled MnO 2 /P-RGO//RGO asymmetric supercapacitor (ASc) shows the maximum energy density of 59.2 W h kg −1 at 1.48 kW kg −1 and could remain 28.8 W h kg −1 at the maximum power density of 57.6 kW kg −1 . Additionally, the MnO 2 /P-RGO//RGO ASc also exhibits excellent long cycling stability with 91.6% of the initial capacitance after 10,000 cycles at 20 A g −1 , indicating its promising practical application for high-efficiency supercapacitors.
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SOLAR ENERGY MATERIALS AND SOLAR CELLS
·
2019
·
IF 6.019
Jingxian He,Guohu Zhao,Peng Mu,Huijuan Wei,Yanning Su,Hanxue Sun,Zhaoqi Zhu,Weidong Liang,An Li
Cost-effective and scalable solution to fabricate high-performance photothermal materials is the key to enable widespread application for solar steam generation. Herein, we report the facile and scalable fabrication of monolithic porous foam based on cross-linked aromatic polymer (PDVB-PS) using styrene as monomer and divinylbenzene as cross-linking agent through a facile one-step hydrothermal method . The resulting PDVB-PS foam possesses well-controlled porous structure , open channel structure, low apparent density and low thermal conductivity (0.038Wm −1 k −1 ). After modification with sodium alginate and polypyrrole , the as-modified PDVB-PS (named as PPy-coated M-PDVB-PS) shows a superhydrophilic wettability (water contact angle ∼ 0°) and stronger light absorption ( ca . 90%), which could dramatically enhance its water transportation ability and photothermal property. Taking advantages of these unique physicochemical properties mentioned above, a high solar-vapor conversion efficiency of 87.6% for the PPy-coated M-PDVB-PS was obtained under 1-sun irradiation, showing great potentials for real applications. More importantly, as a kind of representative synthetic polymers , the success in employment of the PPy-coated M-PDVB-PS as efficient photothermal materials shown in this study may also open a new opportunity for rational design and fabrication of polymer-based solar generators derived from commercial available low-cost raw chemicals with simple and scalable manufacture process for practical solar steam generation on large scale.
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CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Rui Hu,Jiang Xiao,Tianhui Wang,Guangcai Chen,Lin Chen,Xingyou Tian
Properly engineering of surface functionality and structural porosity is critical to improve the sorption performance of biochars. Herein, we report a facile one-pot preparation of phosphate group-functionalized biochars (PBs) derived from bamboo sawdust by engineering with phytic acid prior to pyrolysis. High specific surface areas (629, 1298 and 1109 m 2 ·g −1 ), large pore volumes (0.332, 0.919 and 0.789 cm 3 ·g −1 ), and abundant phosphorous contents (1.14, 3.32 and 1.53 at.%) are achieved compatibly for the PBs pyrolyzed at given temperatures (i.e., 300, 450 and 600 °C) which are significantly higher than those of pristine biochars. Phytic acid not only releases hydrogen protons to tailor biochar matrixes to make micropores created and further developed, but also provides organic phosphorous-containing moiety to guarantee the surface phosphate functionality. PBs extract U(VI) from aqueous media efficiently, i.e., equilibrium achieved within 8 h, high sorption capacity of 229.2 mg·g −1 (at pH 4.0, T 298 K), and favorable selectivity towards U(VI) against the interference of coexisting metal ions. PBs can be regenerated by 0.1 mol·L −1 Na 2 CO 3 and reused well after six recycles. This present work provides a path for the design and synthesis of advanced biochars with favorable potentials in the extraction of U(VI)-containing effluents.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2019
·
IF 3.131
Chenhu Zhang,Yuehua Hu,Wei Sun,Jihua Zhai,Zhigang Yin,Qingjun Guan
In this study, the effect of phytic acid (PA) on the surface properties of scheelite and fluorite was systematically investigated. PA was spontaneously adsorbed onto fluorite through electrostatic and chemical adsorption . By contrast, PA did not appear on the scheelite due to the reaction conditions, surface site, and steric hindrance . XPS measurements were utilized together with a solution chemistry analysis to understand better both the PA selective adsorption mechanism and the key factors derived from multi-layer adsorption onto fluorite, which was found to hinder completely that of NaOl.
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CHEMISTRY-A EUROPEAN JOURNAL
·
2019
·Vol. 25
·期 33
·7826-7830
·
IF 5.16
Tingting Liu,Jianmei Wang,Changyin Zhong,Shiyu Lu,Wenrong Yang,Jian Liu,Weihua Hu,Chang Ming Li
Graphical A fair comparison : A strategy to grow nanoparticles of three Ru phosphides on graphene sheets was developed. The resulting three electrocatalysts for the hydrogen evolution reaction (HER; see figure) show similar morphology, loading density, nanoparticle size, Ru content, and electrochemical surface area, which allows a fair comparison of the effect of the phosphide phase on HER activity. Ru 2 P/graphene shows the best HER performance and highest intrinsic activity in acid solution, and all three electrocatalysts show excellent long-term HER durability. The outstanding electrocatalytic activity of ruthenium (Ru) phosphides toward the hydrogen evolution reaction (HER) has received wide attention. However, the effect of the Ru phosphide phase on the HER performance remains unclear. Herein, a two-step method was developed to synthesize nanoparticles of three types of Ru phosphides, namely, Ru 2 P, RuP, and RuP 2 , with similar morphology, dimensions, loading density, and electrochemical surface area on graphene nanosheets by simply controlling the dosage of phytic acid as P source. Electrochemical tests revealed that Ru 2 P/graphene shows the highest intrinsic HER activity, followed by RuP/graphene and RuP 2 /graphene. Ru 2 P/graphene affords a current density of 10 mA cm −2 at an overpotential of 18 mV in acid media. Theoretical calculations further showed that P-deficient Ru 2 P has a lower free energy of hydrogen adsorption on the surface than other two, P-rich Ru phosphides (RuP, RuP 2 ), which confirms the excellent intrinsic HER activity of Ru 2 P and is consistent with experiment results. The work reveals for the first time a clear trend of HER activity among three Ru phosphide phases.
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ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2019
·
IF 7.149
Shu Xiong,Sheng Xu,Anny Phommachanh,Ming Yi,Yan Wang
Polyamide TFC membranes are widely applied in membrane-based water treatment but generally suffer various fouling problems. In this work, the layer-by-layer assembly of phytic acid (PA) and metal ions (M) is constructed on the surface TFC membrane for the first time, to improve the bio/organic fouling resistances and separation performance of TFC membranes simultaneously. The PA molecule with six phosphonic acid groups of strong chelation ability acts as the organic ligand, and the metal ion acts as the inorganic cross-linker, inducing the assembly of hydrophilic and antibacterial PA-M (Ag or Cu) complexes on the TFC membrane surface. Various characterizations including FTIR, XPS, SEM, AFM, and EDX are employed to confirm the successful and uniform modification of PA-M. FO performance of the PA-M modified TFC membranes, i.e., TFC_PA-Ag and TFC_PA-Cu, is optimized by varying PA concentration and assembly cycles, where the water flux can be improved by 57% and 68%, respectively, without compromising the membrane selectivity. Additionally, the PA-M modification improves the biofouling and organic fouling resistances of the TFC membrane remarkably, owing to the enhanced antibacterial ability and hydrophilicity. The modified TFC membranes are also proven to show the excellent stability by the quantitative release test.
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MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 3
·1-11
·
IF 5.479
Zhang Qian,Zhou Dong-Dong,Li Fan,Wang Yin-Zhen,Yang Feng-Qing
A magnetite@graphene oxide nanocomposite was first coated with polyethylenimine and then modified with phytic acid and titanium(IV) ions. The high loading with Ti(IV) and the good hydrophilicity of PEI and PA result in a material that can be applied to the efficient extraction of highly polar nucleobases, nucleosides and nucleotides. The physicochemical properties of the composite were investigated by scanning electron microscopy, transmission electron microscopy, energy dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy, water contact angle measurements, thermogravimetric analysis, and vibrating sample magnetometry. A series of parameters that affect extraction and elution under the conditions of immobilized metal affinity chromatography (IMAC) and hydrophilic interaction liquid chromatography (HILIC) were examined. The analytes were eluted from the nanocomposites using 10 mM trisodium phosphate as the elution solution in the IMAC mode, and 50% methanol-water as elution solution in the HILIC mode. Figures of merit include (a) an intra-day precision of 0.1–1.0% in the IMAC mode; (b) an intra-day precision of 0.4%–0.8% in the HILIC mode; (c) detection limits between 1.8–2.8 ng mL −1 in the IMAC mode; and (d) detection limits of 4.0–10.5 ng mL −1 in the HILIC mode. The method was applied to the extraction of the nucleotides cytidine-5′-monophosphate (CMP), uridine-5′-monophosphate (UMP), guanosine-5′-monophosphate (GMP), and adenosine-5′-monophosphate (AMP), and the nucleobases and nucleosides hypoxanthine, adenosine, cytosine, inosine and cytidine from Cordyceps sinensis , Lentinus edodes and plasma samples.
Schematic presentation of the workflow for the extraction of nucleobases, nucleosides and nucleotides using phytic acid-Ti(IV) functionalized magnetite@graphene oxide nanocomposites under two distinct modes.
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