Surfaces and Interfaces
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2025
·
IF 6.3
Yuanyuan Feng,Bin Xu,Zhiqing Tian,Shuang Zhao,Hongyu Liu,Bingli Pan,Jiaxing Li,Rama Layek
The effective storage and delivery of lubricating oils within polymeric materials is crucial for enhancing their tribological performances. In this study, hollow Juncus effusus (JE) fibers with a diameter of 2.14 mm were employed as efficient carriers of paraffin wax (PW) in the epoxy resin (EP) matrix. The microstructure, morphology, and mechanical properties of the resulting epoxy resin/ Juncus effusus /paraffin wax (EP/JE/PW) composites were systematically characterized. Furthermore, the influence of PW content on the tribological performances of EP/JE/PW composites was studied. The results revealed that the average friction coefficient of the EP/JE/PW (1:20) was 0.19, and the wear rate was 6.06 × 10⁻ 5 mm 3 /N·m. Compared to pure EP, the composite exhibited an 80 % reduction in friction coefficient and an 88.02 % reduction in wear rate due to the solid-liquid dual lubrication mechanism. We report the use of biomass JE fibers for the effective storage and delivery of PW to enhance the tribological performances of EP for the first time. This study offers new insights into efficient oil storage and intelligent oil delivery in polymeric matrices using biomass-based JE fibers as an oil carrier and oil transport pathway.
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Advanced Healthcare Materials
·
2025
·
IF 9.6
Zhanlin Zhang,Kun Wei,Jie Meng,Junwu Wei,Yupeng Su,Huan Tan,Xiaohong Li
Piezoelectrodynamic therapy (PEDT) is compromised by hypoxia dilemma of tumors, while starvation therapy is constrained by insufficient enzyme activities. To address these challenges, Janus piezoelectric nanoparticles (NPs) are proposed to spatially immobilize glucose oxidase (GOx) and catalase (CAT), enabling piezoelectric potential-amplified enzyme activities and synergistic PEDT-starvation tumor therapy. Here hollow barium titanate (hBT) NPs are synthesized using SiO 2 templates, followed by partial Au deposition via the Pickering emulsion-masking method to create Janus hBT@Au NPs, which are then conjugated with GOx and CAT on opposing sides to yield C-hBT@Au-G NPs. The hollow structure of hBT enhances flexibility and deformation under ultrasonication, while Schottky heterojunctions with Au layers promote charge carrier transfer, amplifying piezoelectric effects and free electron transfer to boost GOx activities. Piezoelectric field-enhances selective tumor cell internalization of NPs and PEDT generation of reactive oxygen species (ROS), coupled with self-propagated GOx/CAT cascades, intensify tumor cytotoxicities and deplete intracellular adenosine triphosphate. The Janus architecture, ultrasonic cavitation, and O 2 generation collaboratively drive robust propulsion for efficient NP accumulation and deep ROS penetration into tumor tissues, thereby achieving full tumor suppression with negligible systemic toxicity. This design overcomes delivery barriers of tumor accumulation, intratumoral penetration, and cellular uptake and synergizes PEDT-starvation tumor therapy.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Ling Zhou,Ao Chen,Zhenzhen Liu,Chong Tao,Jing Ding,Jieru Guo,Hao Wu,Weiyi Zhou,Xipo Zhao
Long-term protection of skin-defect wounds is challenging for the common wound dressings cotton gauze due to its weak skin adhesion, limited drug-loading capacity and frequent replacement. Hydrogels are considered as the promising wound dressings benefiting by their good mechanical compatibility and biocompatibility. Nevertheless, the hydrogels always suffer from the drawbacks of fast water evaporation, lack of antibacterial ability and uncontrollable drug release, which greatly shorten their long-term wound protection duration. Herein, a novel and multifunctional phase change gel (PCG) combining flexibility of hydrogel and release-controllable ability of phase change materials (PCMs) was fabricated through a facile solvent-exchange strategy. Specifically, the bacterial cellulose (BC)/polyethylene glycol based phase change gels (BC/PEG PCGs) were prepared by direct impregnation of BC hydrogel into massive PEG melts. The solvent-exchange mechanism between BC hydrogel and PCM melts was firstly studied based on the impregnation experiments of BC gels into various PCMs. The as-prepared BC/PEG PCGs were then characterized in terms of structure, mechanical, phase change and wound dressing properties, subsequently. This work provides a comprehensive understanding of the structure relationship on their excellent flexibility, good adhesive, skin-cooling, antibacterial and controllable drug-release functions of BC/PEG PCGs, extending their potential in the long-term protection of skin-defect wounds.
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MOLECULES
·
2025
·Vol. 30
·期 11
·2429
·
IF 4.6
Wei Wang,Xiangyao Chen,Wen-Can Huang,Simiao Di,Jie Luo
This study presents a multilayer magnetic Janus sub-micrometric particle (MMJSP) as a nanoreactor for lipase catalysis. The core of the nanoparticle is constructed from a core-shell Fe3O4@SiO2framework, which serves as a precursor for the sequential amino and aldehyde modifications using 3-aminopropyltriethoxysilane and benzaldehyde. Following localized etching and subsequent modification with N,N-dimethyldodecylamine, a Janus nanoparticle with distinct hydrophilic and hydrophobic domains is synthesized. The resulting MMJSP demonstrates a stable attachment to the reaction interface and significantly enhances lipase performance, exhibiting 1.4-fold and 1.6-fold enhancements in activity after immobilization during 1 h hydrolysis and 24 h esterification reactions, respectively. Additionally, the storage stability of the immobilized lipase is improved by 100% over a period of 30 days. Reusability assessments reveal that the immobilized enzyme retains 80.7% activity after 10 cycles of esterification and 80.6% after 50 cycles of hydrolysis, with the magnetic properties allowing for rapid separation and recovery of the immobilized enzyme.
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Advanced Science
·
2025
·Vol. 12
·期 21
·2412158
·
IF 14.1
Lei Ren,Yangnan Hu,Xiaoqiong Ding,Menghui Liao,Tian Shen,Sixing Cao,Hui Zhang,Hong Cheng,Yanru Qi,Pan Feng,Xinyi Pang,Ling Lu,Huan Wang,Wenwen Liu,Renjie Chai,Lin Cheng
Severe to profound sensorineural hearing loss seriously affects the communication and cognitive ability of the patients. Cochlear implantation (CI) is currently the most effective treatment, while it may damage the remaining inner ear function due to its poor biocompatibility and the resultant fibrosis. Herein, a porous methacrylated poly(dimethylsiloxane) (MA-PDMS)-coated cochlear electrode is presented for CI and hearing protection. The porous MA-PDMS is filled with a hybrid hydrogel system made of dexamethasone sodium phosphate (Dex), Ti 3 C 2 T x MXene (MXene), and methacrylate gelatin (GelMA). The coating shows good biocompatibility and drug loading and release capacity in vitro, protective effects on hair cells (HCs) and spiral ganglion neurons (SGNs) of the inner ear, as well as the residual hearing protection and the effective fibrosis reduction in vivo. It is anticipated that this porous electrode drug-loading coating may provide a valuable reference strategy for the future cochlear electrode transplantation system.
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COLLOIDS AND SURFACES B-BIOINTERFACES
·
2025
·
IF 5.6
Qingyun Jiang,Shuai Shao,Zunhui Zhao,Na Li,Hangyu Zhang,Bo Liu
In this study, we engineered dual-network amphiphilic ionic hydrogel microspheres as microcarriers for culturing in mesenchymal stem cells (MSCs), enhancing stemness retention and proliferation. The microspheres were termed DCsa. We innovatively integrated the zwitterionic sulfobetaine methacrylate (SBMA) into the DCsa microsphere structure, and with its outstanding superhydrophilic properties, formed high-energy hydration barrier sites with strong electrical neutrality on the surface of the microspheres. These sites can efficiently block the adsorption of non-specific proteins, ensuring the maintenance of stemness in long-term cultured MSCs. In addition, the addition of AAm endows the surface of microspheres with abundant functional site groups, which exhibit significant promoting effects on cell adhesion and proliferation processes. Functional assessments confirmed that MSCs cultured on DCsa maintained high cells viability and stemness over extended periods. These findings underscore the potential of DCsa microspheres as an effective three-dimensional (3D) culture platform for the large-scale propagation of MSCs, offering significant implications for the advancement of regenerative medicine and cell therapy.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
·
IF 5.4
Wenqing Xie,Jianwen Hu,Jian Yang,Xinyu Yuan,Junjie Fan,Haotian Gao,Tianhao Zhang,Jingwen Wang,Chunling Li,Shuangqing Sun
This study introduces a novel pH-responsive Janus emulsifier based on snowman-shaped NH 2 -PS@SiO 2 Janus nanoparticles, demonstrating exceptional interfacial activity and intelligent demulsification control. The synthesized particles achieved a significant reduction in oil-water interfacial tension by 15.08 mN/m at a 1 wt% concentration, while forming stable Pickering emulsions with average droplet sizes of 72.04 μm. The system exhibited rapid and reversible pH-responsive behavior: immediate demulsification occurred under acidic conditions (pH < 7) through amino group protonation, whereas alkaline conditions (pH > 7) maintained stability via deprotonation. Zeta potential measurements confirmed charge-switching capability across a pH range of 2–12, enabling four cycles of controlled emulsification-demulsification. The unique amphiphilic Janus architecture facilitated vertical anchoring at oil-water interfaces, substantially enhancing emulsion stability compared to homogeneous counterparts. This work establishes a versatile platform for smart emulsion systems requiring on-demand destabilization.
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Waste and Biomass Valorization
·
2024
·
IF 2.6
Luo Bo,Liu Huiyu,Shan Rui,Zhang Jun,Yuan Haoran,Chen Yong
Purpose This work aims to investigate the thermal behavior and kinetic characteristics of polyethylene (PE) pyrolysis over Cu/Ce modified ZSM-5. The influences of metal types, particles size of active center and interaction of Cu–Ce species on products distribution are elucidated. Methods Metal-modified ZSM-5 catalysts were prepared by negative pressure impregnation method. Catalytic fast pyrolysis and thermogravimetric experiments were conducted using Py–GC/MS and TG/MS for the qualitative and quantitative analysis of pyrolysis products. Results Morphology characterization indicated the interaction of Cu–Ce species facilitated the regulation of active center size into a nanoparticle scale. The final products were restricted to a carbon number of less than 9 over CuCe/ZSM-5. Cu–Ce modification increased the aliphatic content from 58.5 to 76.1%. Kinetic analysis revealed a remarkable reduction in activation energies during both the intermediate and final stages, where an average decrease of 30% was achieved. Conclusion The synergistic effects of Cu 0 and CeO x facilitated the formation of more short chain olefins by enhancing C–C bonds cleavage activity. Undesired polycyclic aromatic hydrocarbons (PAHs) were avoided by the optimal steric hindrance of CuCe/ZSM-5. Graphical Abstract
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ACS Nano
·
2025
·
IF 16
Hengdong Ren,Chensi Zhou,Ka Wang,Ximing Zhang,Lei Feng,Wenqing Wei,Yuqing Sun,Yukang Liu,Jun Dai,Xiaobing Xu,Zhiyong Zhang,Xinglong Wu
Interface polarization (one of the slow polarizations) is considered the primary mechanism driving microwave absorption (MA), but limitations in material composition and microstructure design often lead to weak interfacial polarization relaxation. In this work, we developed an interesting heterostructure consisting of carbon nanotube-encapsulated α-Fe2O3 nanocolumns (CNTs@α-Fe2O3). The curvature effects of CNTs induce a built-in electric field between CNTs and α-Fe2O3 nanocolumns, facilitating effective interface polarization. Under microwave irradiation, electron accumulation at the interfaces, driven by the energy-level mismatch between the two materials, further strengthens interface polarization, leading to a highly efficient MA performance. This heterostructured material achieves a minimum reflection loss of −74.1 dB at a thickness of 1.8 mm and an effective absorption bandwidth (reflection loss ≤ −10 dB) of 5.2 GHz (11.9 ∼ 17.1 GHz) at a thickness of only 1.5 mm. X-ray photoelectron spectroscopy and Raman scattering show a distinct blueshift in the Fe 2p binding energy and the A1g mode energy (exclusively associated with Fe atom vibrations), suggesting substantial charge transfer and redistribution at the interface associated with enhanced interface polarization. This work provides insights into interface polarization through the strategic design of energy levels and materials.
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ACS Applied Bio Materials
·
2025
·
IF 4.7
Ji Xia,Jin Huang,Yixiao Yan,Chenxin Jian,Jiansheng He,Nisha Wang,Lei Shi,Qiyang Ding,Hao Tian,Wei Gao
Mitochondrial damage occurs as an initial event following ischemic onset, and the extent of mitochondrial dysfunction is highly correlated to the severity of ischemia-induced cell death. Once appropriate therapeutic interventions are provided, the ischemic tissue can be salvaged, which is of great significance in achieving better neurological outcomes. Herein, we developed a nanosized starch as a targeting nanoplatform, featuring effective blood-brain barrier (BBB) penetration through lactoferrin-mediated transcytosis. Notably, the nanostarch-based delivery of Mdivi-1 and Alda-1 enables controlled release in the acidic lysosome of neurons, effectively inhibiting the pathological mitochondrial fission and metabolizing toxic aldehydes, thereby creating protective effects on maintaining mitochondrial function. Moreover, we demonstrated that mitochondrial protection induces a transition from activated pro-death responses to a pro-survival state by reducing the release of pro-apoptotic proteins, significantly contributing to the long-term recovery of neurological function. Overall, our nanostarch provided an in-depth understanding of the delivery of mitochondrial protectants and underscored the potential and utility of mitochondrial protection for ischemic stroke via minimizing neuronal apoptosis.
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Advanced Materials Technologies
·
2025
·
IF 6.2
Shuangshuang Miao,Lingyu Sun,Xiangdong Liu,Yongping Chen
Ice accretion on airplane surfaces, power lines, or wind turbines causes severe detrimental effects on commercial and residential activities. A great deal of effort has been made to prepare facile and environmentally friendly anti-icing and de-icing surfaces over the last several years. Herein, we present a novel paraffin-infused polyurethane-carbon nanotubes micro-nanostructured icephobic surface (PIPCS) with desired photothermal, electrothermal, and switchable hydrophobic/slippery wettability features for anti-/deicing. The hydrophobic characteristic prevents the ice/frost formation, and the slippery property accelerates the removal of supercooled liquid water. The light-trapping effect from carbon nanotubes endows the film with superior non-contact deicing ability via light irradiation. Furthermore, spatiotemporal control of frost crystal growth on a surface could be achieved via coordination of the strength of cooling and irradiation. Additionally, for the scenarios of sunlight absence, PIPCS exhibits an outstanding electrothermal deicing ability under low voltage. The above properties make PIPCS a promising all-weather anti-icing surface for passive anti-icing and non-contacting deicing in high-altitude equipment and power transportation systems.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Tianyi Zhang,Lanxin Li,Shuhao Zhao,Fei Hu,Niancai Peng
Under-oil open sessile droplets (UOSD), a microfluidic system in which aqueous droplets are confined by an immiscible oil layer, integrate the inherent advantages of both open and closed systems. These include free accessibility, high flexibility, and allowance for gas exchange, while preventing evaporation and contamination, making them ideal for separated biological and chemical reaction units. However, the overlay oil barrier, though effective in protecting droplets from external interference, also poses challenges for micromixing within the droplets. Developing an efficient micromixing strategy for UOSD is therefore essential, to overcome the slow diffusion limit. In this study, we present a contactless and highly efficient micromixing strategy for this immiscible phase system. Mixing in our proposed approach is induced by generating Faraday waves at the oil-air interface, which periodically deform the lower droplets and drive internal convective flows. We document the substrate oscillations, the resulting nonlinear standing waves, and the associated droplet vibrations. The improvement in the rate of both solid-phase reaction (a 5.86-fold improvement compared to static) and liquid-phase mixing (completion within 15 s), attributed to the micromixing effect, is demonstrated. Additionally, we validated effectiveness of the under-oil droplet micromixer as a nucleic acid extraction unit, which is superior to the conventional tube-based method. The Faraday wave-assisted micromixing strategy, with its high controllability and robust performance, provides a promising tool for the operation of under-oil biological and chemical microreactors.
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