Carbohydrate Polymer Technologies and Applications
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2024
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IF 6.2
Xiaojiang Xie,Lihao Wu,Jizhong Huang,Jingwei He,Fang Liu
The traditional small molecular rubber antioxidants have the shortcomings of single function, toxicity, and heavy dependence on non-renewable fossil resources, which limits their green, high-efficiency, and sustainable development in the rubber industry. To address this problem, in this work, we first developed a chitosan derivative containing 10-undecenoyl groups (COS-UC) and then combined it with the natural small molecular antioxidant gallic acid (GA) to prepare chitosan derivative containing 10-undecenoyl and galloyl groups (COS-UC-GA). The obtained COS-UC-GA was used as multifunctional modifier and applied in styrene-butadiene rubber (SBR)/silica composites. The effects of COS-UC-GA on the curing characteristics, crosslinking density, morphology, mechanical properties, and interfacial interaction of SBR/silica composites were explored in detail. The results indicated that the COS-UC-GA can effectively accelerate the vulcanization process of SBR/silica compounds, promote the uniform dispersion of silica, improve the mechanical properties of SBR/silica composites, and significantly enhance the interfacial interaction between the silica and rubber. This research provides a new perspective for developing green and eco-friendly multifunctional modifiers, which not only contributes to the comprehensive utilization of biomass resources, but also can promote the green development of the rubber industry.
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高影响因子
WORLD JOURNAL OF GASTROENTEROLOGY
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2025
·Vol. 31
·期 34
·109825
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IF 5.4
Peng-Tuo Xiao,Chang-Feng Li,Yuan-Da Liu,Jing Zhong,Xi-Lun Cui,Chang Liu,Wei Yang
BACKGROUND Colorectal cancer (CRC) is a major global health burden. B cell CLL/lymphoma 10 (BCL10), a key component of the caspase recruitment domain protein-BCL10-mucosa-associated lymphoid tissue lymphoma paracaspase complexes, is upregulated in CRC and associated with poor patient prognosis, suggesting its potential role in CRC development and progression. Cuproptosis, a novel form of programmed cell death, has emerged as a promising therapeutic strategy for cancer. AIM To explore the role of BCL10 in regulating the sensitivity of CRC cells to cuproptosis. METHODS A series of in vitro and in vivo experiments were conducted using CRC cell lines and CRC mouse models to evaluate the effects of BCL10 on CRC cell proliferation, migration, invasion, and sensitivity to copper-induced cell death. Mechanistic studies were performed to elucidate the underlying molecular pathways. RESULTS BCL10 promoted CRC cell proliferation, migration, and invasion, while its knockdown had the opposite effects. BCL10 also influenced the sensitivity of CRC cells to cuproptosis, with BCL10 overexpression enhancing resistance and its knockdown increasing sensitivity. The mechanism involved BCL10 modulating the expression of DLAT, a key protein in the copper-induced cell death pathway, through activation of the nuclear factor kappa-B (NF-κB) signaling pathway. CONCLUSION BCL10 promotes CRC growth and regulates the sensitivity of CRC cells to cuproptosis by activating the NF-κB signaling pathway and modulating DLAT expression. These findings provide a molecular basis for developing BCL10-targeted therapies for CRC.
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高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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2025
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IF 14.3
Zifan Zou,Liang Xu,Ji Zou,Shuaihang Qiu,Jingjing Liu,Wei Ji,Wenwen Wu,Zhenhao Han,Weimin Wang,Zhengyi Fu
High-entropy borides (HEBs) are emerging as promising candidates for extreme environmental applications due to their exceptional thermal stability, mechanical properties, and tunable electromagnetic properties. This study presents the first systematic investigation of rare-earth-doped deca-component high-entropy borides, (TM 0.9 RE 0.1 )B 2 , (TM = Zr, Hf, Nb, Ta, Ti, W, Cr, V, Mo and RE = Sc, Y, Gd, Dy, Ho, Er, Lu, Sm, Eu, Tm, Tb, Pr, Yb). Evaluations of multiple descriptors, including electron work function and mixing enthalpy, revealed that Sc-containing decaboride (HEB10-Sc) exhibits superior single-phase formation capability. In contrast, the widely used valence electron concentration parameter proved inapplicable due to identical outer-electron counts across rare-earth elements. Boro/carbothermal reduction (BCTR) experiments at 1650°C, employing transition metal oxides, rare-earth oxides, and B 4 C as precursors, demonstrated that Sc uniquely enables the formation of a single-phase diboride with nine group IVB-VIB transition metals, unlike other rare-earth dopants. The phase evolution mechanism during the BCTR process was elucidated: ScBO 3 , formed in situ during BCTR, exhibits greater reducibility resistance than the most refractory HfO 2 , thereby suppressing polyboride formation (common in other rare-earth systems) and facilitating single-phase HEB10 formation. The resulting HEB10-Sc displays outstanding electromagnetic wave absorption performance, achieving a reflection loss (RL) of −35.3 dB at 10.6 GHz (3 mm thickness) and an effective absorption bandwidth of 4.7 GHz in the X and Ku bands. These findings underscore the critical role of rare-earth doping in tailoring the structural and functional properties of high-entropy borides, offering a pathway to design advanced multifunctional materials for extreme environments such as thermal protection and high-temperature electromagnetic absorption in aerospace and electronic applications.
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MATERIALS RESEARCH BULLETIN
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2025
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IF 5.7
Chunyang Guo,Fengdi Wang,Jiao Wang,Haiyan Liu,Bingyan Han,Gaohong He
Photocatalytic systems often suffer from rapid charge recombination and demanding operational requirements. Current photocatalytic oxidation reactions often require the addition of external oxidants. Herein, we develop nitrogen-doped carbon dots (CDs) as a highly efficient photocatalyst with H 2 O as electron acceptors. The optimized CDs achieve exceptional degradation of methyl orange and rhodamine B with rate constants of 0.275 min -1 and 0.307 min -1 , significantly surpassing many reported catalysts. Under ambient sunlight, they rapidly oxidize TMB within 10 s by generating hydroxyl radicals (·OH) from H 2 O. Nitrogen doping elevates the valence band to 2.94 eV, exceeding the ·OH formation potential, while pyrrole N and the conjugated π-system enhance water adsorption and electron transfer. Radical trapping confirms ·OH as the primary active species. This work provides a new paradigm for solar-driven oxidation via rational molecular-level design.
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JOURNAL OF CHROMATOGRAPHY A
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2025
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IF 4
Na Yang,Xingyuan Zhang,Juanqiong Ma,Liqing Ouyang,Zhiyong Xie,Pei Li,Xiao Lin,Qiongfeng Liao,Yanlong Chen
Paclitaxel is one of the most effective anticancer drugs ever developed and remains in high demand. Currently, most commercially available paclitaxel is produced via semi-synthesis, with key precursors like 10-deacetylbaccatin III (10-DAB) extracted from branches and leaves of yew trees. However, its low natural abundance (approximately 0.1%), the complexity of the extraction process, and the low purity of the final product present significant challenges. To address these challenges, we developed a three-dimensional covalent organic framework-based molecularly imprinted polymer (3D COF-MIP) as a novel adsorbent for the selective extraction of 10-DAB. The 3D COF-MIP demonstrated rapid adsorption kinetics (equilibrium time less than 60 min), high selectivity (imprinting factor, 6.7), and exceptional adsorption capacity. Notably, the material retained 93.5% of its initial adsorption capacity after five consecutive adsorption-desorption cycles. The developed method was successfully applied for the selective extraction and determination of 10-DAB in Taxus baccata leaves from different regions with 84.3% purity. The result demonstrated the possibility of direct extraction of 10-DAB from Taxus baccata leaves by 3D COF-MIP. This work provides a new strategy for employing COFs-MIPs to selectively extract pharmacologically active compounds from medicinal plants.
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ACS Applied Nano Materials
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2025
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IF 5.5
Tao Jiang,Jin Zhang,Miaomiao Han,Yadong Liu,Shengxiang Ji
Directed self-assembly (DSA) of block copolymers (BCPs) has shown great potential for creating sub-10 nm patterns for advanced semiconductor manufacturing. It is necessary to develop block copolymers with high Flory–Huggins interaction parameters (χ) and similar surface energies (γ) between constituent blocks. Herein, this work presents the synthesis of lamellae-forming poly(4-chlorostyrene-b-methyl acrylate) (P4ClS-b-PMA) and investigates the DSA behavior of P4ClS-b-PMA. P4ClS-b-PMA has a higher χ than poly(styrene-b-methyl methacrylate) (PS-b-PMMA) and poly(styrene-b-methyl acrylate) (PS-b-PMA), resulting in the smallest achievable period (L0) to 14.1 nm. Notably, the P4ClS and PMA blocks possess similar γ values, which facilitates the formation of perpendicularly orientated domains in P4ClS-b-PMA films on neutral, substrate-modified silicon wafers under thermal annealing. 7× density multiplication DSA of P4ClS-b-PMA is successfully demonstrated in films on chemical patterns fabricated by 193 immersion (193i) lithography, with a feature size of about 7.5 nm. These findings confirm that P4ClS-b-PMA could be a potential candidate for DSA lithography.
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JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
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2025
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IF 6
Xiaoyu Ji,Yuxin Tang,Xin Feng,Jiajin He,Hongyan Tang
In this study, NF membranes (DP NF membranes) with high permeability and excellent antifouling performance were fabricated by 3,5-diaminobenzoic acid (DABA) with steric hindrance through interfacial polymerization and grafting quaternized cationic cellulose derivative polyquaternium-10 (PQ10). The incorporating of DABA and PQ10 was verified through XPS and FTIR characterization. Smoothness of membrane surface was revealed through SEM and AFM. The modified membranes showed a remarkable increase in hydrophilicity, as evidenced by a reduction in water contact angle from 67.07° for PVDF to 30.70° for DP NF membranes. The water flux of the DP NF membrane reached 33.7 L·m −2 ·h −1 . MgSO 4 and Na 2 SO 4 rejection rates of DP NF membranes were 96.4 % and 94.1 %, respectively. DP NF membranes demonstrated high flux recovery ratios, achieving 97.6 % for bovine albumin, 96.8 % for humic acid, 96.4 % for sodium alginate, and 95.4 % for oil/water emulsion. After three fouling cycles, a slight decline was observed to DP NF membranes. Besides, rejection rates and water flux values exhibited no substantial alterations following long-term fouling tests that lasted for 100 h. These findings indicated that the membranes possessed high permeability and excellent antifouling performance, offering a facile and effective method for creating NF membranes for advanced water treatment applications.
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JOURNAL OF CHEMICAL THERMODYNAMICS
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2016
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IF 2.196
Pan Liang,Jie Wang,Zhi-Hong Liu
A pure zinc borate, Zn[B 12 O 14 (OH) 10 ], has been synthesized and characterized by XRD, FT-IR, simultaneous TG-DTA techniques, and chemical analysis. The molar enthalpy of solution of Zn[B 12 O 14 (OH) 10 ] (s) in 1 mol·dm −3 HCl(aq) was measured by microcalorimeter at T = 298.15 K. The molar enthalpy of solution of ZnO(s) in the mixture solvent of 2.00 cm 3 of 1 mol·dm −3 HCl(aq) and calculated amount of H 3 BO 3 was also measured. With the incorporation of the previously determined enthalpy of solution of H 3 BO 3 (s) in 1 mol·dm −3 HCl(aq), together with the use of the standard molar enthalpies of formation for ZnO(s), H 3 BO 3 (s), and H 2 O(l), the standard molar enthalpy of formation of −(9646.6 ± 9.6) kJ·mol −1 at T = 298.15 K was obtained on the basis of an appropriate thermochemical cycle. In addition, the molar enthalpy of formation of −9492.7 kJ·mol −1 for [B 12 O 14 (OH) 10 ] 2− has also been estimated by a group contribution method, which has been used to predict the Δ f H m θ of a series of transition metal borates of M[B 12 O 14 (OH) 10 ] (M II = Mn, Zn, Fe, Co, Ni). These estimated data have been used to further compare the stability of this series of transition metal borates.
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International Journal of Biological Sciences
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2022
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IF 10.75
Wuping Yang,Kenan Zhang,Zedan Zhang,Jingcheng Zhou,Lei Li,Yawei Xu,Jianhui Qiu,Lin Cai,Yanqing Gong,Kan Gong
Our previous study has proved that down-regulation of CLDN10 (Claudin-10) in ccRCC (clear cell renal cell carcinoma) was closely related to tumor metastasis and predicted an unfavorable prognosis by analyzing TCGA-KIRC data. However, the effects of CLDN10 on the progression of ccRCC and its mechanisms of action remain elusive. During the study, a large number of clinical samples were utilized to verify the reduced expression of CLDN10 in ccRCC and its association with tumor metastasis and poor prognosis, and our results confirmed that lower CLDN10 expression was an independent predictor of shorter OS (HR: 4.0860, 95%CI: 2.4737-6.7490, P<0.0001) and DFS (HR: 4.3680, 95%CI: 2.2800-8.3700, P<0.0001) in metastatic ccRCC patients. CLDN10 overexpression accelerated cell apoptosis and restrained cell proliferation, migration and invasion in vitro . Besides, CLDN10 overexpression suppressed ccRCC growth and lung metastasis and promoted apoptosis in orthotopic models. Mechanistically, we found that CLDN10 overexpression up-regulated the acetylation and expression levels of ATP5O (ATP synthase subunit O, mitochondrial), leading to the dysfunction of mitochondrial, thereby suppressing the growth and metastasis of ccRCC through increasing the levels of NDUFS2, ROS, Cleaved-Caspase 3, E-cadherin and SDHB and decreasing the levels of N-cadherin and mitochondrial membrane potential. Moreover, knockdown of ATP5O expression based on the overexpression of CLDN10 could reverse the increase in NDUFS2, ROS, Cleaved-Caspase 3, E-cadherin and SDHB levels, the decrease in N-cadherin and mitochondrial membrane potential levels and the inhibition of ccRCC phenotypes caused by CLDN10 overexpression. Taken together, these findings for the first time illuminate the mechanism by which CLDN10 overexpression suppresses the growth and metastasis of ccRCC.
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高影响因子
JOURNAL OF LUMINESCENCE
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2025
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IF 3.6
Chen Chang,Shixu Tao,Chang Xu,Yu Zhang,Wenxin Jiang,Yongge Cao,Chaoyang Ma
Silica aerogels are ideal templates for nanomaterial encapsulation due to high porosity and narrow pore size distribution (<10 nm) but suffer from poor mechanical strength. Polymethylsilsesquioxane (PMSQ) aerogels present better strength and transparency, yet their large pore size (10–30 nm) limits nanoparticle embedding. This study employed surface modification using hexamethyldisilazane (HMDZ) combined with ambient pressure drying (APD) to fabricate transparent, crack-free PMSQ xerogel monoliths featuring ∼10 nm nanopores, improved mechanical robustness and enhanced hydrophobicity. The effects of preparation conditions on the microstructure, transmittance, and thermal conductivity of the xerogels were systematically investigated. Furthermore, HMDZ-modified PMSQ xerogel monoliths were effectively utilized as mesoporous hosts for CsPbBr 3 quantum dots (QDs). The resulting CsPbBr 3 QDs@PMSQ composite monolith combined the high transparency, low density and hydrophobicity of PMSQ xerogels with the strong luminescence of QDs. The composites exhibited a PLQY of 37% along with outstanding moisture stability, photostability, and thermal stability. A white LED fabricated using the CsPbBr 3 QDs@PMSQ composite monolith, red K 2 SiF 6 : Mn 4+ phosphors and a blue GaN chip exhibits bright emission with CIE coordinates of (0.23, 0.24), a luminous efficiency of 100 lm/W and approximately 132% coverage of the NTSC 1931 color gamut with outstanding long-term device stability. These results highlight the potential of HMDZ-modified PMSQ xerogel monoliths as promising mesoporous hosts for nano-functional materials, especially for stabilizing perovskite QDs in optoelectronic applications.
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高影响因子
APPLIED SURFACE SCIENCE
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2012
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IF 2.103
Zhongbo Li,Guowen Meng,Ting Liang,Zhuo Zhang,Xiaoguang Zhu
We report a facile low-cost synthetic approach to large-scale Ag nanosheet-assembled films with a high density of uniformly distributed sub-10 nm gaps between the adjacent nanosheets on Si substrates via galvanic cell reactions. The distribution density of Ag nanosheets on substrates could be tailored by tuning the duration of the HF-etching and the concentration of citric acid in the solution. Furthermore, in conjunction with a conventional photolithography, highly uniform patterned Ag nanosheet-assembled structures with different morphologies can be achieved on Si substrates via galvanic-cell-induced growth. By using rhodamine 6G as a standard test molecule, the large-scale Ag nanosheet-assembled films exhibit highly active and homogenous surface-enhanced Raman scattering (SERS) effect and also show promising potentials as reliable SERS substrates for rapid detection of trace polychlorinated biphenyls (PCBs).
研究领域:
纳米材料
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等离激元学
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表面科学
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分析化学
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传感器
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2026
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IF 5.4
Hao Yu,Jiakai Shi,Jiaqi Wen,Shi Liu,Jingyu Cai,Linxi Hou
Permittivity is a key parameter characterising the polarisation capacity of a dielectric, and directly influences a material’s signal transmission and energy storage properties. As electronic devices evolve towards higher frequencies and greater integration, there is an increasing demand for polymer materials that combine low dielectric constant with excellent thermal and environmental stability. In this study, a aluminium-based metal-organic framework material CAU-10-H, which exhibits negative thermal expansion, was synthesised using the hydrothermal method and incorporated into PEEK matrix by hot-press to prepare CAU-10-H/PEEK composite films. The as-obtained CAU-10-H is relatively well dispersed within the PEEK matrix at low-to-moderate filler loadings, while its incorporation is associated with a reduction in the dielectric constant of the composite. The reduced dielectric response is mainly attributed to the introduction of low-polarity nanoporous domains, while the increase in free volume fraction may also contribute to this behaviour. When the filler content is 5 wt%, the composite exhibits a low die This may be attributed to the following factors:lectric constant across the 2–18 GHz frequency range, with an average value as low as 2.45, whilst the thermal decomposition temperature is above 500℃. In addition, this composite material offers moisture resistance, excellent dimensional stability, outstanding frequency stability and good signal integrity. This study provides new insights into the regulation of the high-frequency dielectric properties and stability of polymer composites using microporous materials with negative thermal expansion characteristics. Download: Download high-res image (181KB) Download: Download full-size image Owing to the inherent microporous structure of MOFs and their interaction with the polymer matrix, this composite material achieves a dual reduction in both the dielectric constant and dielectric loss at high frequencies, whilst exhibiting excellent thermal stability and superior moisture resistance.
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