MICROCHEMICAL JOURNAL
·
2019
·
IF 3.206
Mengling Lin,Yingjie Guo,Zhiyong Liang,Xuesong Zhao,Jianan Chen,Yilin Wang
Biothiols, generally including glutathione (GSH), cysteine (CySH), and homocysteine (HcySH), are important biomarkers and closely related to many diseases. In this work, a simple method for the spectrophotometric determination of the three biothiols was developed. The proposed method was based on the fact that Fe 3+ could oxidize 3, 3′, 5, 5′-tetramethylbenzidine (TMB) to oxidized TMB (ox-TMB) and induce a blue color solution corresponding to an absorption peak centered at 652 nm. However, the introduction of a biothiol compound could cause the reduction of ox-TMB which resulted in a blue color fading and a decrease of the absorbance. Based on this finding, we developed a method for the determination of biothiols with the help of UV–vis spectroscopy, and the influence of different factors including pH, temperature, and incubation time was studied when glutathione worked as an example. The detection limits for GSH, CySH, and HcySH were 1.04, 0.82, and 2.09 μM, respectively. More importantly, the suggested method was successfully applied for the determination of GSH in human serum samples with the recovery of 97%–112%. This method is simple, fast and without the use of complicated nanomaterials .
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高影响因子
FUEL
·
2016
·
IF 3.611
Junmei Wang,Zehui Zhang,Shiwei Jin,Xizhou Shen
Catalytic conversion of carbohydrates into valuable chemical and liquid fuels has received considerable attention in recent years. In this study, sulfonic acid-functionalized ordered mesoporous carbon (OMC-SO 3 H) was prepared and well characterized by physical techniques such as TEM, nitrogen physisorption measurements and XRD. The as-prepared OMC-SO 3 H was then used for the acid-catalyzed conversion of fructose based carbohydrates into 5-hydroxylmethylfurfan (HMF) or 5-ethoxymethylfurfural (EMF). Due to the high surface area and high acidity, the OMC-SO 3 H catalyst showed a comparable catalytic performance as the homogeneous catalysts. The dehydration of fructose over the OMC-SO 3 H catalyst produced a high HMF yield of 89.4% in DMSO at 120 °C within 30 min. The one-pot transformation of fructose carbohydrates were also smoothly performed, affording EMF yields of 55.7%, 53.6% and 26.8% from fructose, iuline and sucrose after 24 h at 140 °C, respectively. Furthermore, the OMC-SO 3 H catalyst can be reused and no apparent loss of the activity was observed.
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高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Dongsheng Jiang,Yuzhe Li,Chao Zhang,Ruifang Wang,Jinpeng Zhu,Wen Chen,Yusi Che,Jilin He
Bayan Obo tailings are rich in niobium and other valuable elements; however, the phase evolution of niobium-bearing slag within these tailings remains poorly understood. This knowledge gap significantly impedes comprehensive utilization of these strategic resources. In this study, a CaO-SiO 2 -Nb 2 O 5 -5%Na 2 O-5%Al 2 O 3 -3%CaF 2 slag system was investigated to examine the phase equilibrium types, compositional characteristics, and distributional evolution under varying w (CaO)/ w (SiO 2 ) ratios and w (Nb 2 O 5 ) contents, using high-temperature equilibrium experiments. Following a 24-hour high-temperature equilibrium treatment at 1473 K under an argon atmosphere, a range of compounds including 13CaO·8SiO 2 ·Nb 2 O 5 ·CaF 2 , 2CaO·4SiO 2 ·Na 2 O·Al 2 O 3 , CaO·Nb 2 O 5 ·NaF, 2CaO·Nb 2 O 5 , and CaO·SiO 2 were identified. An increase in Nb 2 O 5 content coupled with a reduction in the w (CaO)/ w (SiO 2 ) ratio favored the formation of CaO·Nb 2 O 5 ·NaF (pyrochlore phase) and 2CaO·Nb 2 O 5 . These two phases exhibited high Nb concentrations, with the CaO·Nb 2 O 5 ·NaF (pyrochlore) phase containing up to approximately 70% Nb. The optimal smelting conditions for niobium enrichment in the pyrochlore phase were identified within the range of w (CaO)/ w (SiO 2 ) = 0.74∼0.80 and w (Nb 2 O 5 ) = 13.61%∼16.11%.
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高影响因子
FUEL
·
2024
·
IF 6.7
Zhuo Wang,Huiling Zheng,Fanhui Meng,Tingjun Fu,Zhong Li
The use of ZSM-5@Zn/ZSM-5 core@shell nanocrystals as integrated catalyst for efficient aromatic production from methanol aromatization is demonstrated. By combining the attributes associated with core@shell structural and acidic features, ZSM-5@Zn/ZSM-5 exhibited synergistic and improved catalytic performance toward methanol aromatization. The effect of Zn/ZSM-5 shell thickness and the acid density of the ZSM-5 core on synergistic performance was systematically investigated. Results showed that aromatic selectivity could be increased with shell thickness and the acid density of the ZSM-5 core, while catalytic stability was subject to the optimization on both shell thickness and core acid density. The strengthening of dehydroaromatization on the shell catalyst after Zn introduction and the hydrogen transfer for aromatization with increasing core acid density was confirmed. A double boost on catalytic stability from methanol conversion along with 40.7% increase on aromatic selectivity could be achieved for core@shell catalyst with a coating ratio of 0.3 compared with that on single core catalyst. The fabrication of ZSM-5 core with low SiO 2 /Al 2 O 3 ratio for Zn/ZSM-5 not only provided more acid sites to promote the aromatization, but also promoted the dealkylation of the formed aromatics, which could enhance the selectivity of light aromatics and catalytic lifetime. The findings in the work not only enrich the family of core@shell composite zeolite catalysts, but also provide the fundamental understanding on the aromatization process over core@shell structural features.
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高影响因子
BIOORGANIC CHEMISTRY
·
2025
·
IF 4.7
Lixin Niu,Yun He,Xing Zhang,Yanfei Peng,Ding Wang,Tao Wang,Zunting Zhang
A concise and efficient photo-induced rearrangement and oxidation of 2-(3-methylbenzofuran-2-yl)-3-phenyl-1 H -indoles 1 for the synthesis of 5-(2-hydroxyphenyl)-5-methyl-5,7-dihydro-6 H -benzocarbazol-6-ones 2 is described. Irradiation of compounds 1 in anhydrous dichloromethane solution, using 313 nm UV light in an air atmosphere, resulted in the formation of compounds 2 with yields ranging from 55% to 98%. Using the 6π-electrocyclization strategy of compounds 1 containing a methyl, a quaternary carbon stereocenter was introduced in the compounds 2 . The carbonyl group of compounds 2 was formed by the photo-induced oxidation of C-H bond to C-OH and hemiketal-keto tautomerization. Additionally, the antitumor activities of compounds 2 were evaluated and found to demonstrate equivalent or superior activity compared to Cisplatin against various tumor cell lines, including leukemia HL-60, lung cancer A549, liver cancer HepG2, breast cancer MDA-MB-231 and colon cancer SW480. The anticancer activity of compound 2f was particularly significant, with IC 50 values of 2.99, 9.06, 6.81, 9.29, and 14.93 μM respectively, and its IC 50 value of normal cells 11.18 μM. Compound 2k had a relatively high IC 50 values against cancer cells, whereas its IC 50 value greater than 40μM for normal cells.
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DOI
PubMed
高影响因子
ChemistryOpen
·
2019
·Vol. 8
·期 12
·1437-1440
·
IF 2.205
Yu-Xin Yue,Yong Kong,Fan Yang,Zhe Zheng,Xin-Yue Hu,Dong-Sheng Guo
Graphical Keeping an eye on enzymes : We designed a supramolecular tandem assay based on the guanidinocalix[5]arene and fluorescein reporter pair, which realized quantitative detection of pyridoxal-5′-phosphate. Guanidinocalix[5]arene and fluorescein reporter pair has been chosen to set up a supramolecular tandem assay principle based on the differential recognition of pyridoxal-5′-phosphate (the substrate of alkaline phosphatase, ALP), pyridoxal (the product of ALP) and phosphate (the product of ALP). This supramolecular tandem assay system offers an opportunity to monitor the activity of ALP in a label-free, continuous, and real-time manner. More importantly, a calibration curve can be given for selective and quantitative detection of pyridoxal-5′-phosphate (biomarker for several diseases).
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PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 5
·1772-1776
·
IF 3.288
Xin Shu,Yongren Chen,Chunling Yuan,Yilin Wang
A novel and sensitive method for ascorbic acid (AA) determination utilizing Ag+–3,3′,5,5′-tetramethylbenzidine (TMB) as a colorimetric probe was proposed. In a weak acidic medium, Ag+ could oxidize TMB to oxidized TMB (ox-TMB) and cause a blue color solution with an absorption peak centered at 652 nm. However, the addition of AA could induce the reduction of ox-TMB, leading to shallower blueness and lower absorbance. Under the selected experimental conditions, there was a good linear relationship between the decrease of absorbance (ΔA) and AA concentration in the range of 0.5–60 μM, and the detection limit was as low as 0.23 μM. The feasibility of this method was verified in commercial beverages with recoveries of 95.8–104.1%. The method has the advantages of simplicity and practicability. More importantly, no nanomaterials need to be prepared.
研究领域:
分析化学
·
食品科学
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高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2017
·Vol. 17
·期 3
·2201-2205
·
IF 1.483
Yuan Lin,Li Zhong Yan,Zhang Min,Yuan Xian You,Zhu Xiao Qing
A series of novel sodium 2-alkyl-5-(ethoxycarbonyl)-1,3-dioxane-5-carboxylate surfactants were synthesized in high yield using nanosolid superacid sulfonated carbon as a catalyst and characterized by 1H NMR, IR and elemental analysis. Critical micelle concentration (CMC)
of the surfactants was determined and the results showed that the CMC values were less than 1.0 × 10–3 mol/L. Other relevant surface properties were also evaluated, such as emulsion stability, foam ability and degradability. In relation to emulsion formation, foam stability
and the range of application of temperature, the new surfactants showed better properties than traditional surfactants when used as an emulsifier in emulsion polymerization. Moreover, the surfactants were stable under alkaline and neutral conditions, and degraded into raw materials under acid
condition. Convenient synthesis process with high yield and superior properties promisingly make the title compounds to be a type of ‘environmentally friendly’ surfactants.
研究领域:
表面活性剂化学
·
绿色化学
·
纳米催化
·
高分子科学
·
胶体与界面科学
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高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2016
·Vol. 16
·期 1
·1085-1089
·
IF 1.338
Yuan Lin,Jia Guo Kai,Li Zhong Yan,Zhang Min,Yuan Xian You
A series of novel sodium (5-methyl-2-alkyl-1,3-dioxane-5-yl) carboxylate surfactants were synthesized using nanosolid superacid SO4
2−/Fe2O3 as a catalyst and characterized by 1H NMR, IR and elemental analysis. The critical
micelle concentration (CMC) of surfactants was determined and the results showed that the CMC values were less than 2.0 × 10−3 mol/L. Other relevant surface properties (Krafft point, emulsion stability, foam ability, degradability) were also evaluated. It was suggested
that with respect to emulsion formation, foam stability and the range of application temperature, compared with traditional surfactants, the new surfactants could give better results and showed better properties when used as an emulsifier in emulsion polymerization. In addition, the surfactants
were stable under neutral and alkaline conditions, and could form solid under acid condition. The solid will generate the original surfactants for reuse with alkali. Sodium (5-methyl-2-alkyl-1,3-dioxane-5-yl) carboxylate is likely to be a new type of ‘environmentally friendly’
surfactant.
研究领域:
胶体与界面化学
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应用化学
·
绿色化学
·
高分子科学
·
催化化学
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高影响因子
BIOORGANIC CHEMISTRY
·
2026
·
IF 5.1
Xincheng Sun,Changkang Li,Jimei Liu,Ridao Chen,Dawei Chen,Jungui Dai
The 6/5/6 to 6/6/5 ring system rearrangement from indole alkaloids strictosidine ( 1 ) and strictosamide ( 2 ) to quinoline alkaloid pumiloside ( 3 ) is an essential but unelucidated process in the biosynthesis of camptothecin, especially, the intermediates involved in the process have not been identified. Herein, the nonenzymatic conversions including spontaneous reaction from 1 to 2 , and light- or flavin-catalyzed skeletal rearrangement from 2 to 3 have been discovered. Particularly, the crucial biosynthetic intermediate strictosamide ketolactam ( 2a ) with dicarbonyl nine-membered ring involved in the conversion from 2 to 3 is obtained and structurally characterized. Moreover, the successive conversion from 1 to 3 is achieved in Nicotiana benthamiana . These findings not only provide a new insight into and better understanding for the biosynthesis of camptothecin with rare nonenzymatic reactions, also lay the foundation for further elucidation of the biosynthetic pathway of camptothecin.
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高影响因子
JOURNAL OF FLUORESCENCE
·
2022
·Vol. 32
·期 3
·983-992
·
IF 2.525
Chen Yuliang,Lai Kaijie,Cai Jinmi,Li Yicheng,Wang Haibo
Chirality plays a pivotal role in drugs, agrochemicals and food additives et al. The enantiomers of a chiral molecule often show huge difference in bioactivity, metabolism, and toxicity et al. thereby, the recognition of chiral molecules shows an increasingly important priority. In this paper, a novel method for chiral fluorescence recognition based on anthracene fluorescent dyes (AD) ⊂ water-soluble pillar[5] arene containing phosphonic acid group (PWP[5]) is developed. The AD as guest molecule can complex with PWP [5] to form 1:1 AD ⊂ PWP[5] assembly, and this assembly can be further used as a fluorescent probe to identify D/L-phenylalanine and D/L-phenylalaninol by fluorescent titration. The fluorescence intensity of the assembly was significantly reduced for D-phenylalanine and D-phenylalaninol, while L-phenylalanine or L-phenylalaninol was added to AD ⊂ PWP[5] assembly, the fluorescence intensity of the assembly almost unchanged. Hence, the chiral recognition based on assembly between the achiral fused ring fluorescent dye and achiral PWP[5] was developed.
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PubMed
高影响因子
APPLIED CLAY SCIENCE
·
2022
·
IF 5.907
Xuemin Zhong,Yanfu Wei,Samahe Sadjadi,Dong Liu,Mengyuan Li,Ting Yu,Guanzheng Zhuang,Peng Yuan
Aerobic oxidation of biomass-derived 5-hydroxymethylfurfural (HMF) to 2, 5-furandicarboxylic acid (FDCA) is an important reaction for producing green and sustainable chemicals. Herein, natural clay mineral palygorskite (Pal)-supported bimetallic Pt–Pd catalyst for the oxidation of HMF to FDCA in water without the addition of any bases was developed. The 1Pt 9 Pd 1 /Pal catalyst with Pt/Pd molar ratio of 9/1 exhibited excellent catalytic performance, and 100% HMF conversion and 99% FDCA yield were obtained under optimum reaction conditions after 12 h, which was mainly attributed to the synergy between palygorskite and bimetallic Pt–Pd nanoparticles . Palygorskite used as support realized the immobilization and dispersion of bimetallic nanoparticles, increasing the catalytic activity . The basicity of palygorskite and alloying effects between Pt and Pd facilitated the formation of FDCA by synergistically catalyzing the oxidation of alcohol and aldehyde groups in the reactants and intermediates. Furthermore, this catalyst showed good stability and reusability . The present work provides a highly efficient, cost-effective, and environmentally benign catalyst for the base-free oxidation of HMF to FDCA in practical industrial applications.
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高影响因子
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