MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Wenwen Wang,Xin Jiang,Junyi Huang,Yuchan Ma,Jiaxin Xian,Zhifeng Fu,Yuting Zhao,Hui Ouyang
Although pyrene-based fluorophores possess some merits including outstanding fluorescent (FL) emission and long-lived excited intermediates, their practicability have been dramatically limited by an obvious aggregation-caused quenching (ACQ) impact. Due to the isolation effect of metal-organic frameworks (MOFs), pyrene-based fluorophores are utilized as the FL dopant rather than organic ligands to anchor onto the porous supports for inferior ACQ effect along with enhanced FL emission. Herein, a one-step alkaline coprecipitation method was proposed to efficiently load 4,4′,4″,4″‘-(1,9-dihydropyrene-1,3,6,8-tetrayl)tetrabenzoic acid onto ZIF-8 MOFs (Py@ZIF-8). Since ZIF-8 effectively rigidified the location of the FL emitter, the decreased ACQ effect of Py@ZIF-8 was realized along with an intriguing FL quantum yield of 77.3 %. Furthermore, the protective activity of the rigid framework endowed Py@ZIF-8 with an attractive long-term FL stability. Note that, green FL microspheres could remarkably quench the luminescent signal of Py@ZIF-8 based on the marked Förster resonance energy transfer (FRET) effect. The FRET donor-acceptor pair of Py@ZIF-8 and green FL microspheres was employed to establish a sandwich ratiometric FL protocol for cardiac troponin I. Superior to a traditional single-signal mode, the dual-signal ratiometric mode displayed an enhanced sensitivity, wherein a low detection limit of 0.5 pg/mL (3σ) was achieved. Moreover, the quantitation results of cardiac troponin I in serum samples by the proposed FL method showed a good agreement with those by a commercial Abbott chemiluminometer. The reliable ratiometric platform exhibited improved precision and preferable feasibility of pyrene-doped MOFs in sensitive diagnosis and trace testing.
研究领域:
分析化学
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生物化学
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材料科学
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纳米技术
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医学诊断
✓ 已验证
产品关联
DOI
高影响因子
ChemistrySelect
·
2025
·Vol. 10
·期 28
·e00259
·
IF 2
Bo Yang,Hai Xing,Yang Xia,Xin Wang,Ningning Liu
Graphical ZIF-8 was synthesized through an in-situ growth method within a PVDF membrane matrix. The PVDF/ZIF-8 composite membrane was subsequently prepared via the phase inversion method using immersion precipitation. The ZIF-8 particles were uniformly distributed in the PVDF/ZIF-8 composite membrane. The widespread use of organic dyes in industrial processes has led to increasing environmental pollution due to the discharge of dye-contaminated wastewater, necessitating more efficient dye removal methods. In this study, a poly(vinylidene fluoride) (PVDF)/ZIF-8 composite membrane was fabricated via a phase inversion method using immersion precipitation, with ZIF-8 synthesized via in-situ growth within the membrane matrix. The composite membranes were thoroughly characterized using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and thermogravimetric analysis (TGA). The ZIF-8 particles were uniformly distributed in the PVDF/ZIF-8 composite membrane. The adsorption performance of the PVDF/ZIF-8 composite membrane was evaluated for methyl green (MG) removal. At 313 K with an adsorbent dose of 10 mg, the membrane exhibited an adsorption capacity of 172.30 mg g⁻¹ and a removal ratio of 87.21%, demonstrating that the incorporation of ZIF-8 significantly enhanced adsorption performance. Adsorption isotherm studies revealed that the process followed the Freundlich model, while kinetic analysis indicated a pseudo-second-order mechanism. Additionally, thermodynamic investigations suggested that the adsorption was endothermic and spontaneous. The major driving force for adsorption was identified as electrostatic interactions between the dye and the membrane. These findings highlight the potential of PVDF/ZIF-8 composite membranes for effective dye removal from wastewater.
研究领域:
环境科学
·
材料工程
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化学工程
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Yang Wang,Lei Zhang
In this paper, we report a new type of 3D ZIF-8@NiAl-LDHs micro-flowers material consisting of sandwich-like structured 2D nanopetals (highly compact ZIF-8 film anchored on both sides of petals). ZIF-8 was successfully incorporated into NiAl-LDHs (ZIF-8@NiAl-LDHs) via seeding strategy directed growth of ZIFs on the surface of LDHs nanopetals. The coating of ZIF-8 significantly increased the adsorption ability to organic pollutants and inorganic cation. 3D ZIF-8@NiAl-LDHs with excellent enrichment and filtration properties has been exploited for the application in water purification, and exhibit superior high adsorption rate and adsorption efficiency of organic (nonsteroidal anti-inflammatory drugs: ketoprofen, flurbiprofen, indometacin and ibuprofe; anionic dyes: congo red, orange g; cationic dyes: methylene blue, rhodamine b) and inorganic cation (Cu 2+ , Pb 2+ ) residues due to their novel hierarchical and submicroscopic structures. Further, 3D ZIF-8@NiAl-LDHs as filter membrane to extraction four kind of trace anti-inflammatory drugs followed by direct quantification detection of targets with HPLC was demonstrated. The validated method was successfully applied for analysis of four anti-inflammatory drugs in environmental water and human urine samples. This work provided a feasible way to design and construct purification materials for wastewater treatment and contaminant detection.
研究领域:
环境科学
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材料科学
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分析化学
✓ 已验证
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Peipei Song,Zhirui Fan,Shuai Sun,Chengye Sun,Jun Wang
In recent years, lead (Pb) contaminated soil has caused irreversible damage to human beings. It is urgent to develop a novel technology for accurate detection of Pb in the soil solution. Herein, a new electrochemical sensor was fabricated. Fe/ZIF-8 was used as the modification material, gold nanoparticles (AuNPs) were electrodeposited, and DNAzyme was applied on the surface as the probe. Under the optimum conditions (DNAzyme concentration of 1 μmol, fixation time of 4 min, incubation time of 17 h and reaction time of 30 min), the detection range was 5×10 −12 ∼ 5×10 −5 M, and the minimum detection limit was 10 −13 M (3δ). Furthermore, the electrochemical sensor demonstrated outstanding anti-interference ability to common cations, anions, organic compounds and other interference factors. After four consecutive tests, the relative standard deviation (RSD) was only 0.39%, and it still displayed excellent reproducibility with 0.69% of RSD. After 20 days, the sensor’s response to Pb 2+ remained at 93.58%. In addition, the sensor could accurately detect Pb 2+ in the actual soil solutions, and the recoveries of the samples ranged from 92% to 109.4%. In conclusion, this electrochemical sensor can specifically detect Pb 2+ in the soil solution with enhanced sensitivity, anti-interference capability and stability, which is of great significance for Pb 2+ detection in the field.
研究领域:
环境科学
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分析化学
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纳米技术
✓ 已验证
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2021
·Vol. 45
·期 35
·15876-15886
·
IF 3.591
Xiao Zhang,Zhiyue Li,Taoyi Zhang,Jing Chen,Wenxi Ji,Yun Wei
A novel zeolitic imidazolate framework-8 (ZIF-8) alginate composite hydrogel material (PVA/SA@ZIF-8) is an alginate composite bead which was fabricated by grafting ZIF-8 on the surface of the sodium alginate hydrogel beads using an in situ growth method. The synthetic material was characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, high resolution transmission electron microscopy, X-ray photoelectron spectroscopy, and thermogravimetric analysis. The PVA/SA@ZIF-8 bead was used to effectively adsorb Cu(II) from aqueous solutions. The initial concentration of copper ions, adsorbent dose, initial pH of copper ions solution, temperature, and contact time for the synthesis of the material were optimized. The adsorption isotherms and kinetics fitted to the Langmuir isotherm model (R2 = 0.9992) and the pseudo-second-order kinetic model (R2 = 0.9967) respectively. According to the Langmuir isotherm adsorption model, the maximum theoretical adsorption capacity of the adsorbent for Cu(II) was 166.94 mg g−1. In addition, the recycling application of the adsorbent was possible as it was easily collected and reused after five adsorption-regeneration cycles. The results indicated the PVA/SA@ZIF-8 hydrogel has unlimited potential in the treatment of heavy metal wastewater. Moreover, the combination of sodium alginate hydrogel and metal–organic frameworks would broaden the potential application of hydrogel materials in other fields.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
FISH & SHELLFISH IMMUNOLOGY
·
2025
·
IF 3.9
Ying Wu,Jinge Wang,Ziyu Wang,Panpan Zhang,Han Zhang,Guotao Wang,Hong Chen,Zhenjie Cao,Chen Zhang,Jingqun Ao,Yongcan Zhou,Yun Sun
Interleukin-8 (IL8) is a key factor in the promotion and regulation of vertebrate inflammatory and immune responses. In this study, a novel interleukin-8 ( Ca IL8) isolated from the humpback grouper ( Cromileptes altivelis ) was successfully cloned and characterized. The gene comprises a 375 bp open reading frame, encoding a protein of 124 amino acids with an estimated molecular weight of 11.2 kDa and contains four conserved cysteine residues common in other known IL8s. Phylogenetic analysis revealed that Ca IL8 is most closely related to IL8 from Epinephelus lanceolatus , and that both group within a fish-specific IL8 clade. Expression analysis demonstrated that CaIL8 is ubiquitously expressed in all the tested tissues from healthy humpback groupers, with high expression levels in the blood, intestine, brain, and liver. Upon infection with Vibrio harveyi , CaIL8 expression was upregulated in various tissues, and the recombinant Ca IL8 (r Ca IL8) exhibited significant binding to and antibacterial activity against the tested bacterial strains. Furthermore, r Ca IL8 enhanced the chemotaxis and proliferation of the head kidney leukocytes and increased the phagocytic activity of macrophages. In vivo experiments indicated that overexpression of Ca IL8 enhances the fish's ability to inhibit V. harveyi replication, while knocking it down reduces antibacterial capacity. This suggests that in teleosts, Ca IL8 acts as a proinflammatory cytokine, activating immune cells against bacterial infections.
研究领域:
免疫学
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分子生物学
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微生物学
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鱼类健康
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遗传学
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细胞生物学
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Yipeng Pang,Maofang Zhao,Yuhan Xie,Yanping Wang,Yuxin You,Yongding Ke,Chaoyi Zhang,Xiaohan Chen,Yijia Yang,Chunlei Zhang,Xi Chen,Yi Liu,Xingtang Fang
The development of non-antibiotic strategies for combating bacterial infections, particularly through reactive oxygen species (ROS) accumulation accompanying inflammation, has attracted much attention. Despite Allicin (Ac) emerges as a promising antimicrobial agent with wide and remarkable bioactivity, it still displays quite limited ROS scavenging and anti-inflammation capacity due to uncontrolled and poor bioavailability. Herein, a multifunctional nanoplatform with pH-dependent and ROS-scavenging antibacterial, anti-inflammatory and proangiogenic properties is introduced to promote infected wound healing by integrating Ac into silver nanoparticles (AgNPs)-loaded zeolite imidazole framework (ZIF-8), namely Ac@ZIF-8/AgNPs. Primarily, the nanoplatform is activated and controlled release in the infection microenvironment, with disrupting biofilms, scavenging ROS and antibacterial capacitys, outperforming conventional Ac. Moreover, in the mouse models induced by bacterial infection, Ac@ZIF-8/AgNPs can alleviate the inflammatory condition, scavenge ROS, facilitate the regeneration of collagen fiber and enhance vascular formation, collectively accelerating wound healing. Overall, this biocompatible nanoplatform is provided as a reliable approach to solve the long-standing problem of infected wound healing.
研究领域:
纳米技术
·
生物医学工程
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药学
·
伤口愈合
✓ 已验证
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Gen Li,Jinan Li,Ya Wang,Yuhang Du,Hongyan Xu,Yan Wang
In this research, a two-step hydrothermal method was used to fabricate a NO 2 sensor based on WO 3 @ZIF-8 core-shell nanorods grown on ceramic tubes. The material's morphology, nanostructure, and composition were thoroughly characterized. The nanocomposites consisting of WO 3 @ZIF-8 showed significant sensing response (65) toward 50 ppm NO 2 at 200 °C. The WO 3 @ZIF-8 core-shell nanomaterials demonstrated exceptional selectivity to NO 2 against TEA and possessed good repeatability. Moreover, the distinctive core-shell nanorods structure promote the process of transferring the electrical charge of the carrier and the response to the targeted gas. The outer coating of ZIF-8 microporous material, with small pore window size (0.5–0.7 nm), had a sieving effect on large molecular interference gases. Further, we combined density functional theory (DFT) calculations and molecular dynamics simulations to investigate the reaction mechanism of the sensors.
研究领域:
材料科学
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纳米技术
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化学传感器
·
气体检测
·
理论化学
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2020
·Vol. 10
·期 57
·34381-34386
·
IF 3.119
Lele Chen,Jinghao Tian,Huaxing Song,Zhaohua Gao,Haisheng Wei,Wenhua Wang,Wanzhong Ren
Hydroformylation of olefins is one of the most important industrial processes for aldehyde production. Therein, the leaching of active metals for heterogeneous catalysts is an important issue in the hydroformylation reaction, particularly for higher olefins to produce higher alcohols. Here, different Rh/ZnO catalysts with diverse ZnO as a support were investigated and a home-made ZnO50 support was selected to prepare the Rh/ZnO50@ZIF-8 core–shell structure catalyst, which was synthesized by the growth of ZIF-8 with ZnO50 as the sacrificed template to afford Zn source. Compared with the Rh/ZnO50 catalyst, the Rh/ZnO50@ZIF-8 catalyst demonstrated a better cyclic stability in the hydroformylation of 1-dodecene. Combining the experiment and characterization results, it was concluded that the ZIF-8 shell on the Rh/ZnO50 catalyst effectively prevented the leaching of metal Rh into the reaction solution. Moreover, the Rh/ZnO50@ZIF-8 catalyst exhibited good universality for other higher olefins. This work provides a useful guideline for immobilizing the active species in heterogeneous catalysts for the hydroformylation reaction.
研究领域:
催化
·
化学工程
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
LANGMUIR
·
2025
·
IF 3.9
Yingying Cheng,Yuanye Zhuang,Shiyang Bai,Meng Ge,Jihong Sun,Jingjing Sun,Xufeng Gong
The removal of CO2 from biogas is critically important for environmental protection and energy applications yet remains technically challenging in the chemical industry. In this work, novel composite adsorbents featuring ZIF-8 uniformly dispersed on randomly oriented clinoptilolite lamellae (LCP) were designed and fabricated through a straightforward composite method. The synthesis sequentially incorporated metal precursors into LCP via ion exchange and salt addition and then introduced organic ligands to generate ZIF-8. Comprehensive characterizations, including XRD, FT-IR, N2 adsorption–desorption isotherms, SEM, and TG analyses, confirmed the physicochemical properties and structural features of the composites. The synthesized Zn-LCP/ZIF-8 materials exhibited exceptional CO2/CH4 separation performance, demonstrating ultralow CH4 adsorption capacity (<0.1 mmol/g) coupled with superior CO2/CH4 selectivity (≈28). Complementary molecular simulations using Material Studio software provided mechanistic insights into the adsorption and separation behavior, which further confirmed the superiority of the composite structure in CO2/CH4 separation. These results establish an effective strategy for biogas purification, while offering new perspectives for enhancing the CO2/CH4 adsorption selectivity.
研究领域:
环境科学
·
能源技术
·
材料科学
·
化学工程
·
吸附
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Xiqing Liu,Tao Wang,Yongqing Wang
Fluorescence technology enabled highly sensitive, real-time and multi-scenario detection of lysozyme (Lys). However, fluorescent nanomaterials suffer from aggregation-induced quenching, environmental interference and lack of selective recognition capability. In this work, the ZIF-8 was used as a framework to support red and blue fluorescence quantum dots for constructing ratiometric fluorescence sensor. At the same time, combined with molecular imprinting technology, a Molecular Imprinting Polymers (MIPs)-based ratiometric fluorescence sensor was designed for improving the sensitive and selective. The MIPs-based ratiometric fluorescence sensor exhibited highly sensitively and selectively for the detection of lysozyme. Benefited from ratiometric design, the sensor could realize the effect of visual detection of Lys and the limit of detection (LOD) was reached 0.048 mg/L. The HPLC method was used to further confirm the sensor has the potential for practical application. Furthermore, to the demand of an affordable and portable strategy for visual detection Lys, a dexterous and inexpensive test paper was made in this work.
研究领域:
分析化学
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纳米技术
·
荧光传感
·
材料科学
·
生物传感
·
环境监测
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Yaxin Li,Chenci Xu,Jing Mao,Lixia Mao,Weiqi Li,Ziyang Liu,Airi Shin,Jiaqing Wu,Lingli Hou,Dejian Li,Kaili Lin,Jiaqiang Liu
Periodontitis, an inflammatory bone resorption disease associated with dental plaque, poses significant challenges for effective treatment. In this study, we developed Mino@ZIF-8 nanoparticles inspired by the periodontal microenvironment and the unique properties of zeolitic imidazolate framework 8, aiming to address the complex pathogenesis of periodontitis. Transcriptome analysis revealed the active engagement of Mino@ZIF-8 nanoparticles in innate and adaptive inflammatory host defense and cellular metabolic remodeling. Through sustained release of the anti-inflammatory and antibacterial agent minocycline hydrochloride (Mino) and the generation of Zn2+ with pro-antioxidant effects during degradation, Mino@ZIF-8 nanoparticles synergistically alleviate inflammation and oxidative damage. Notably, our study focuses on the pivotal role of zinc ions in mitochondrial oxidation protection. Under lipopolysaccharide (LPS) stimulation, periodontal ligament cells undergo a metabolic shift from oxidative phosphorylation (OXPHOS) to glycolysis, leading to reduced ATP production and increased reactive oxygen species levels. However, Zn2+ effectively rebalances the glycolysis-OXPHOS imbalance, restoring cellular bioenergetics, mitigating oxidative damage, rescuing impaired mitochondria, and suppressing inflammatory cytokine production through modulation of the AKT/GSK3β/NRF2 pathway. This research not only presents a promising approach for periodontitis treatment but also offers novel therapeutic opportunities for zinc-containing materials, providing valuable insights into the design of biomaterials targeting cellular energy metabolism regulation.
研究领域:
牙科学
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纳米技术
·
药学
·
细胞生物学
·
炎症研究
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）