JOURNAL OF HAZARDOUS MATERIALS
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2018
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IF 6.434
Jun Hou,Hanlin Ci,Peifang Wang,Chao Wang,Bowen Lv,Lingzhan Miao,Guoxiang You
The effect of Ca 2+ and alginate on the stability of CeO 2 nanoparticles (NPs) was investigated using dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA); the two methods were then compared. DLS showed rapid aggregation of CeO 2 NPs in 8 mM Ca 2+ solution; however, NTA showed that some primary aggregates (200–400 nm) still remained—a result that was obscured in DLS measurements. Aggregation of alginate molecules was also studied using DLS and NTA, where NTA particle concentration and video provided additional information on the alginate aggregation progress. Finally, DLS showed that in the presence of alginate, the aggregation rate and size of CeO 2 NPs increased. NTA intensity measurements provided insight into a heteroaggregation and bridging mechanism. NTA particle concentration and video also showed CeO 2 NPs were linked by alginate gel in high Ca 2+ concentration (>4 mM). the DLS and NTA had different advantages in measuring particle size. DLS could better study the initial aggregation stage and large aggregates, while NTA could better detect small aggregates. NTA also measured particle number concentration, individual intensity, and particle motion video, which provided additional insight. Combining these two methods could help us to better understand the behavior and fate of NPs in water.
研究领域:
环境科学
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纳米技术
·
化学
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DOI
高影响因子
ACS Omega
·
2023
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IF 4.1
Hui Lv,Shiyu Zong,Tong Li,Qian Zhao,Zhiyong Xu,Jiufang Duan
In recent years, conductive hydrogels have received increasing attention as wearable electronics due to the electrochemical properties of conductive polymers combined with the softness of hydrogels. However, conventional hydrogels are complicated to prepare, require high temperature or UV radiation to trigger monomer polymerization, and are frozen at low temperatures, which seriously hinder the application of flexible wearable devices. In this paper, a conductive sensor integrating mechanical properties, adhesion, UV shielding, anti-dehydration, and anti-freeze was prepared based on Ca2+-initiated radical polymerization at room temperature using the synergy of sodium lignosulfonate, acrylamide (AM), and calcium chloride (CaCl2). Metal ions can activate ammonium persulfate to generate free radicals that allow rapid gelation of AM monomers at room temperature without external stimuli. Due to ionic cross-linking and non-covalent interaction, the hydrogels have good tensile properties (1153% elongation and 168 kPa tensile strength), high toughness (758 KJ·m–3), excellent adhesive properties (48.5 kPa), high ionic conductivity (7.2 mS·cm–1), and UV resistance (94.4%). CaCl2 can inhibit ice nucleation, so that the hydrogels have anti-dehydration and frost resistance properties and even at −80 °C can maintain flexibility, high conductivity, and adhesion. Assembled into a flexible sensor, it can sense various large and small movements such as compression, bending, and talking, which is a flexible sensing material with wide application prospects.
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DOI
PubMed
高影响因子
FISH & SHELLFISH IMMUNOLOGY
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2023
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IF 4.7
Lei Diao,Meiqi Ding,Hongzhen Sun,Yawei Xu,Rui Yin,Huijie Chen
Polystyrene microplastics (PM) is a pressing global environmental concern, posing substantial risks to aquatic ecosystems . Microalgal astaxanthin (MA), a heme pigment, safeguards cells against oxidative damage induced by free radicals, which contributes to various health conditions, including aging, inflammation and chronic diseases. Herein, we investigated the potential of MA in ameliorating the immunotoxicity of PM on carp ( Cyprinus carpio L.) based on head kidney lymphocytes treated with PM (250 μM) and/or MA (100 μM). Firstly, CCK8 results showed that PM resulted in excessive death of head kidney lymphocytes. Secondly, head kidney lymphocytes treated with PM had a higher proportion of necroptosis, and the levels of necroptosis-related genes in head kidney lymphocytes were increased. Thirdly, the relative red fluorescence intensity of JC-1 and MitoSox showed decreased mitochondrial membrane potential and increased mtROS in head kidney lymphocytes treated with PM. MitoTracker® Green FM fluorescence analysis revealed enhanced mitochondrial Ca 2+ levels in PM-treated lymphocytes, corroborating the association between PM exposure and elevated intracellular Ca 2+ dynamics. PM exposure resulted in upregulation of calcium homeostasis-related gene (Orail, CAMKIIδ and SLC8A1) in lymphocytes. Subsequent investigations revealed that PM exposure reduced miR-25-5p expression while increasing levels of MCU, MICU1, and MCUR1 . Notably, these effects were counteracted by treatment with MA. Furthermore, PM led to the elevated secretion of inflammatory factors (IFN-γ, IL-1β, IL-2 and TNF-α), thereby inducing immune dysfunction in head kidney lymphocytes. Encouragingly, MA treatment effectively mitigated the immunotoxic effects induced by PM, demonstrating its potential in ameliorating necroptosis, mitochondrial dysfunction and immune impairment via regulating the miR-25-5p/MCU axis in lymphocytes. This study sheds light on safeguarding farmed fish against agrobiological threats posed by PM, highlighting the valuable applications of MA in aquaculture.
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PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2024
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IF 8.3
Di Meng,Haipeng Xie,Bin Yan,Weixuan Zhao,Yiming Fu,Wenjihao Hu,Yongli Gao
Quartz is a key raw material in high-tech fields (such as photovoltaics and semiconductor microelectronics), and the most efficient extraction method of quartz is mineral flotation. Quartz activation plays a crucial role in mineral flotation. However, the mechanism underlying the process remains unclear, and the role of additional metal ions is controversial. In this study, the interaction forces between the quartz surface, the dodecylamine (DDA) cation/sodium oleate (NaOL) anion mixed collectors, and Ca2+ were analyzed using atomic force microscopy in order to systematically explore the activation process of quartz flotation. The results confirmed that the activation process was initialized from NaOL, which was adsorbed on the surface of a calcium-covered quartz surface. The existence of DDA inhibited the binding of Ca2+ to NaOL so that more Ca2+ was adsorbed on the quartz surface to provide the adsorption site for NaOL. Moreover, the best adsorption condition of Ca2+ + NaOL + DDA mixed solution was analyzed by quartz crystal microbalance with dissipation, and it demonstrated that the most stable chemisorption environment on the quartz surface was at pH 11.0. In these circumstances, Ca2+ could first adsorb in a point-like manner on the quartz surface, which was then adsorbed with a mixture of NaOL and DDA. This result showed that, at a specific pH, Ca2+ could encourage the coadsorption of cationic/anionic mixed collectors on quartz. This work provides an important new understanding of the intermolecular interactions that take place during complex mineral flotation processes between chemical additives and mineral surfaces. The methodology used in this study can be easily adapted to different interfacial processes, including water treatment, membrane technology, bioengineering, and oil production.
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PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2019
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IF 3.45
Yuan Zhong,Nan Zhou,Mao Xia,Yue Zhou,Hongxi Chen,Zhi Zhou
Indoor cultivation has attracted more and more concerns in the last few years. Searching for ideal red-emitting phosphors for this application has been a great challenge. In this paper, a novel red-emitting phosphor SrAl 3 BO 7 :Mn 4+ (SABO:Mn 4+ ) had been synthesized through a modified hydrothermal reaction method for the first time. Three kinds of effect parameters, including hydrothermal reacting time, sintering temperature and Mn 4+ doping concentration, were comprehensively considered to optimize the phase purity and luminescent properties of the SABO:Mn 4+ phosphor. Besides, the luminescent properties of SABO:Mn 4+ was systematically investigated through UV–vis absorption spectra , PLE and PL spectra, CIE chromaticity coordinate and decay times. The excitation band of this phosphor locates in the wavelength range of 250–550 nm, resulting from Mn 4+ → O 2− charge transfer and electron transitions from 4 A 2 – 4 T 1 , 2 T 2 and 4 T 2 energy levels. Meanwhile, a sharp emission band is detected from 600 to 700 nm with two emission peaks located at 648 and 662 nm, which is assigned to 2 E → 4 A 2 characteristic transition of Mn 4+ . In addition, Mg 2+ /Zn 2+ /Ca 2+ are co-doped as charge compensators to improve the luminescent properties of SABO:0.03Mn 4+ . The impacts of doping concentration of Mg 2+ /Zn 2+ /Ca 2+ on the photoluminescent intensity, QE and thermal stability of SABO:0.03Mn 4+ phosphor is investigated carefully. The corresponding mechanism is discussed via decay times, EPR spectra and configurational coordinated diagram. More importantly, the EL spectrum of as-fabricated pc-LED device matches well with the absorption of plant pigments, demonstrating this novel phosphor can regard as a promising red-emitting luminescent material to meet the light requirement in plant growth LED lighting.
研究领域:
材料科学
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光学工程
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植物学
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DOI
高影响因子
FOOD CHEMISTRY
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2022
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IF 9.231
Swati Mahato,Da-Wen Sun,Zhiwei Zhu
This work studied the effects of electromagnetic fields (EMF) with frequencies between 100 and 400 Hz and a fixed strength of 12 mT on cold storage of grass carp at 4 °C for 30 min, and Ca 2+ ATPase enzyme activities, and lipid and protein oxidations in samples were measured to assess changes in intracellular Ca 2+ concentration and oxidative stability. Results showed higher Ca 2+ ATPase activities in samples treated with EMF frequencies. Significant ( p < 0.05) decreases occurred in protein oxidation for samples treated between 100 and 300 Hz, but an increase was observed for treatment with 400 Hz. However, the lipid oxidation increased for samples treated up to 200 Hz and decreased with further increase in frequency to 300 and 400 Hz. Nuclear magnetic resonance analysis showed that exposure to different frequencies of EMF could reduce the association of water molecules with protein for both bound and immobilized water. Overall, treatments of EMF between 100 and 400 Hz could improve grass carp quality during cold storage.
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PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2022
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IF 9.136
Weiyan Luo,Yixin Chen,Ping Hu,Wei Ruan,Yueyuan Ye,Zhifeng Zheng,Shuirong Li,Dechao Wang,Duo Wang
A heterogeneous extracting route of 4-ethylguaiacol is constructed using the intermediate of the reaction between 4-ethylguaiacol and Ca 2+ as the extracting agent. In this work, 4-ethylguaiacol with different concentrations (70, 80, 90, 95%) is prepared using 40 v/v% ethanol aqueous solution as the mother liquor. The extraction parameters optimization, cycle extraction and 4-ethylguaiacol purification are studied, respectively. Extracting parameters investigated are reaction temperature (4–80 ℃), extraction time (5–60 min), and pH value (6.5–13). 4-ethylguaiacol extraction efficiency keeps above 90% at the optimum extracting conditions at the reaction temperature of 4–20 ℃, the extraction time of 30 min, and the pH value of 6.5–10. Further cycle extraction experiments are carried out under the optimal extraction parameters using the intermediate as the extracting agent. After 36 cycle extraction times, the extraction efficiency of 4-ethylguaiacol can still reach 91.7%. Guaiacol has similar physical and chemical properties to 4-ethylguaiacol, thus it is used as an impurity to test the extraction and purification effect of the heterogeneous extracting method. With increasing the cycle extraction times from 1 to 4, 4-ethylguaiacol purity reaches more than 99% for all four mother liquors with different initial concentrations. 4-ethylguaiacol purity of 99.57% is achieved through twice cycle extraction when its initial content in the mother liquor is 95%.
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高影响因子
ACS Biomaterials Science & Engineering
·
2020
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IF 4.152
Pan Gu,Bing Li,Bisheng Wu,Jiping Wang,Peter Müller-Buschbaum,Qi Zhong
The controlled hydration, transition, and drug release are realized by adjusting layer thickness in thermoresponsive interpenetrating polymeric network (IPN) hydrogels on cotton fabrics. IPN hydrogels are synthesized by sodium alginate (SA) and poly(N-isopropylacrylamide) (PNIPAM) with a ratio of 1:5/% (w/v). The cotton-fabric-supported IPN hydrogels with a thickness of 1000 μm exhibit a transition temperature (TT) at 35.2 °C. When the hydrogel thicknesses are thinned to 500 and 250 μm, the TTs are reduced to 34.8 and 34.1 °C, respectively. Interestingly, the morphology of IPN hydrogels switches from a well-defined honeycomb-like network structure (1000 μm) to a densely packed layer structure (250 μm). The thinner layers not only present a smaller extent of hydration and collapse but also require longer time to reach an equilibrium state, which can be attributed to the more pronounced hindrance of the chain rearrangement by the cotton fabrics. To address the influence of layer thickness on the drug release, we compare the release rate and cumulative release percentage of the test drugs tetracycline hydrochloride (TCH) and levofloxacin hydrochloride (LH) between pure IPN hydrogels and cotton-fabric-supported IPN hydrogels (250, 500, and 1000 μm) at 25 °C (below the TT) and 37 °C (above the TT). Because of the compressive stress from the collapsed hydrogels, a higher release is observed in both hydrogels when the temperature is above TT. The cotton fabric induces a slower and less prominent drug release in IPN hydrogels. Thus, combining the obtained correlation between the transition and hydrogels layer thickness, the drug release in cotton-fabric-supported IPN hydrogels can be regulated by the layer thickness, which appears especially suitable for a controlled release in wound dressing applications.
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PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2021
·
IF 4.527
Lei Zhang,Xuefeng Zhang,Chaoyong Zhao,Xuan Xiao
Eu 3+ -activated Sr 3 −x Ca x La(VO 4 ) 3 phosphors were fabricated via citric-acid-assisted sol combustion. Characterization of the Sr 3 −x Ca x La(VO 4 ) 3 :Eu 3+ samples with different concentrations of Ca 2+ revealed a hexagonal crystal structure belonging to the R -3 m space group. The amount of Ca 2+ added ( x ) was controlled within 0 ≤ x ≤ 2 to yield high-purity phosphors. Scanning electron microscopy results showed that an increase in Ca 2+ concentration resulted in a decrease in the particle size of Sr 3 −x Ca x La(VO 4 ) 3 :Eu 3+ , with the shape gradually changing from nearly equiaxed to lath-shaped. The Sr 2 CaLa(VO 4 ) 3 :Eu 3+ phosphor (denoted as SCLVO:Eu 3+ ) exhibited the strongest photoluminescence (PL) intensity at 618 nm among the samples under excitation of 394-nm near-UV (NUV) light. The study of Eu 3+ doping concentration confirmed that Eu 3+ could enter the lattice of the SCLVO matrix without altering its crystal structure. SCLVO:Eu 3+ was found to strongly absorb 394 nm NUV light and 464 nm blue light. The optimal concentration of the Eu 3+ dopant in the SCLVO host was 0.11, which resulted in the phosphor achieving an excellent PL intensity and a color purity of 98.68%. Tunable luminescence from the orange area (0.5280, 0.4522) of Commission Internationale de l'éclairage (CIE) to the red area (0.6313, 0.3650) was achieved by adjusting the concentration of Eu 3+ . Under 394 nm excitation, SCLVO:0.11Eu 3+ phosphor has a quantum yield (QY) of 28.2% and excellent thermal stability with 0.383 eV activation energy . Consequently, White-light-emitting diode (WLED) based on SCLVO:0.11Eu 3+ phosphor yielded a high color rendering index (CRI), low correlated color temperature (CCT), and CIE coordinates of 91.8, 5196 K, and (0.3407, 0.3612), respectively, under the 20 mA driven current. These results indicated the tremendous potential of SCLVO:0.11Eu 3+ phosphors for application in WLEDs excited by NUV or blue light.
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高影响因子
Acta Biomaterialia
·
2024
·
IF 9.4
Cong Tang,Kairui Liu,Xiaoning Gao,Hanmeixuan Kang,Weijie Xie,Jin Chang,Linling Yin,Jun Kang
Cuproptosis is an emerging form of programmed cell death and shows enormous prospect in cancer treatment. Excessive generation of reactive oxygen species (ROS), metal ion accumulation, and the tricarboxylic acid (TCA) cycle collapse are pivotal elements in the triggering of cell death via mitochondrial pathways. Herein, a cascade nanoreactor CaCuZC has been constructed by incorporating nanosonosensitizer IR780 carbon dots (IR780 CD) and calcium peroxide (CaO 2 ) into metal-organic frameworks (MOF) for synergistic cuproptosis–ferroptosis and Ca 2+ overload mediated immunotherapy. Within tumor cells, CaCuZC dissociates into CaO 2 , Cu 2+ and sonosensitizer IR780 CD. The decomposition of CaO 2 could generate H 2 O 2 to strengthen the Cu 2+ -based chemodynamic therapy and Ca 2+ overload induces amplified intracellular oxidative stress, thus leading to mitochondrial dysfunction. As a result, the combination of Cu 2+ and Ca 2+ overload together induce cascade mitochondrial damage. Moreover, the sonosensitizer IR780 CD generates ROS under ultrasound irradiation to amplify intracellular oxidative stress. In addition, the overloaded Cu 2+ released from CaCuZC leads to the aggregation of lipoylated protein dihydrolipoamide S-acetyltransferase, thus resulting in cuproptosis. Furthermore, ferroptosis could been concomitantly induced by CaCuZC with intracellular glutathione (GSH) consumption and lipid peroxidation (LPO) accumulation. The cuproptosis–ferroptosis and Ca 2+ overload-enhanced synergistic therapy also activates robust immunogenic cell death. CaCuZC enhances the infiltration and activation of tumor-specific cytotoxic T cells to transform a “cold” tumor into a “hot” tumor, activating the anti-tumor immune response. This study provides a cascade of mitochondrial damage strategy for triggering cuproptosis–ferroptosis and Ca 2+ overload-enhanced immunotherapy and achieving improved therapeutic effects. Statement of significance To improve the efficacy of tumor immunotherapy, a cascade nanoreactor CaCuZC was successfully constructed based on a self-assembly strategy for cuproptosis–ferroptosis and Ca 2+ overload mediated immunotherapy. Upon decomposition within the acidic and GSH-overexpressing tumor microenvironment, CaCuZC released CaO 2 and Cu 2+ and sonosensitizer IR780 CD. The CaO 2 further produced H 2 O 2 /O 2 and Ca 2+ in a weakly acidic environment to strengthen the Cu 2+ -based CDT and IR780 CD-mediated SDT, respectively. The overload copper ions not only led to cuproptosis, but also efficiently induced ferroptosis. The cuproptosis–ferroptosis and Ca 2+ overload-enhanced synergistic therapy also activates robust immunogenic cell death. This study presents a cascade of mitochondrial damage strategy for cuproptosis–ferroptosis and Ca 2+ overload-enhanced immunotherapy.
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PubMed
高影响因子
WATER RESEARCH
·
2022
·
IF 13.4
Wenkai Liu,Changrong Zhao,Shiqing Zhou,Bin Liu,Xiaoxiang Cheng,Zhihao Xue,Tingting Zhu
This study was aimed to evaluate the effects of a pre-treatment involving sulfite (S(IV)) synergistically activated by ultraviolet (UV)/Fe(II) on natural organic matter (NOM)-enhanced Ca 2+ scaling during nanofiltration treatment. Based on the variations in the physicochemical properties and correlation analyses of irreversible resistance, the intrinsic fouling mechanisms were revealed from two aspects: bulk crystallization (interaction between NOM and inorganic ions) and surface crystallization (morphology of surface crystallization and a change in the Ca 2+ concentration in the scaling layer). Furthermore, the degradation contribution rates of different free radicals during the UV/Fe(II)/S(IV) (UFS) treatment process were evaluated. During the reactions in the UFS, three free radicals (SO·–4, OH ·– and e- aq) were generated, and in-situ Fe(III) was formed in-situ . The carboxyl groups of the NOM were attacked by the free radicals, resulting in decreased of carboxyl concentration and density. In addition, the bond between Ca 2+ and NOM weakened, and hydrophobic (HPO) substances were mineralized. However, the Fe(III) formed in-situ was active and electropositive, competing with Ca 2+ for the complexation active sites on the NOM. The synergy effect of bulk crystallization and surface crystallization led to a significant decrease in the particle size of feed solution. The crystal size and roughness of membrane surface also decreased, which was conducive to reducing the membrane irreversible resistance. Correlation analysis revealed that the HPO ratio, carboxyl density and particle size (> 100 nm) ratio were effective characterization parameters for predicting irreversible resistance. This study not only provides guidance for alleviating membrane fouling caused by NOM-enhanced Ca 2+ scaling during the nanofiltration process, but also presents the rationality of irreversible resistance during nanofiltration process and various indicators with strong linear correlation.
研究领域:
环境科学
·
水处理工程
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DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Zihao Chen,Jiamei Han,Xin Gu,Kaikai Wu,Jiabin Jiang,Liming Zhao,Yixin Yan,Haitao Wang,Xiaolu Liang,Yao Wang,Zhenyu Wang,Xiaokun Zhu,Zimeng Pan,Xiang Liu
Perovskite manganese oxides are highly desirable for infrared acquisition owing to their characteristics of ferromagnetic metal-paramagnetic insulators. In this work, the sol-gel spin-coating technique was employed to prepare La 1- x Ca x MnO 3 (LCMO) films with varying Ca 2+ content ( x = 0.1, 0.2, 0.3, 0.4, 0.5) on the (l00) LaAlO 3 (LAO) substrates. In comparison to previous studies, the pre-sintering temperature, final sintering temperature, and final sintering period were modified. The crystal structure, surface topography, elemental valence states, and electrical transport performance of the LCMO films were characterized and analyzed as well. The results demonstrated that the diffraction peaks of the above films were aligned with those of the LAO single-crystal substrate. The change in Ca 2+ content caused an increase in the Mn–O bond length, the amount of Mn 4+ , and the Mn– O –Mn angle in LCMO films, promoting the double exchange effect. These modifications had a considerable impact on the resistivity of LCMO films, increasing their TCR value. The maximum TCR of 22.92% K −1 was reached at x = 0.3 and peak TCR temperature ( T k ) of 241.93 K. Therefore, the film has great application potential for infrared bolometers.
研究领域:
材料科学
·
物理学
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DOI
高影响因子
危险品化学品经营许可证（带存储）