MICROCHEMICAL JOURNAL
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2026
·
IF 5.2
Ming Hong,Helin Niu,Xiao Lian
A Eu-MOG@PAN nanofibrous membrane was fabricated for amikacin sensing. • Amikacin induces red-to-blue fluorescence switching in the solid-state membrane. • Ratiometric detection is achieved without an additional reference fluorophore. • The membrane shows high selectivity with a detection limit of 0.38 μM. • Amikacin in whey was successfully determined by visual and fluorescence analysis. Lanthanide metal–organic materials are attractive for optical sensing, but their application in complex aqueous samples is often hindered by single-channel emission, poor processability and insufficient signal reliability. Herein, we report a flexible mixed-matrix nanofibrous membrane fabricated by confining a europium metal–organic gel (Eu-MOG) within an electrospun polyacrylonitrile (PAN) scaffold. The membrane enables amikacin-triggered ratiometric luminescence sensing via nanoscale interfacial coordination. Upon exposure to amikacin, the amino groups of amikacin coordinate to Eu 3+ sites, perturb the Eu–carboxylate microenvironment and weaken the antenna effect, resulting in strong quenching of the Eu 3+ emission and simultaneous recovery of ligand-centred blue emission at 458 nm. This red-to-blue transformation provides a built-in ratiometric readout (I₄₅₈/I₆₁₉) without the need for an additional reference fluorophore. Control experiments confirm that the 458 nm emission originates from the organic ligand rather than from amikacin or PAN. Mechanistic studies based on fluorescence lifetimes, FT-IR, XPS, zeta-potential and spectral overlap reveal that the response is dominated by amikacin–Eu 3+ coordination and the consequent disruption of ligand-to-Eu 3+ energy transfer. The electrospun membrane offers an open, mechanically robust architecture that facilitates analyte access and solid-state operation. It exhibits high selectivity for amikacin over common inorganic ions, amino acids, and other antibiotics. The ratiometric response is linear over the low-concentration range of 1–9 μM, while the response at 10–100 μM can be described using a Logistic fitting model. The calculated limit of detection is 0.38 μM. The method was successfully applied to the determination of amikacin in whey samples with good reproducibility. This work presents a ligand-emission activation strategy for constructing lanthanide-based ratiometric nanofibrous membranes and demonstrates a portable platform for visual screening of antibiotic residues in dairy products. Download: Download high-res image (286KB) Download: Download full-size image
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高影响因子
OPTICS AND LASER TECHNOLOGY
·
2026
·
IF 5.2
Kaicheng Zhou,Zhongli Wu,Xiaomin Jian,Heng Xu,Xingjun Li,Xinchi Duan,Yingchun Luo
Constructing dual-ligand Eu-MOF fluorescent probes to improve the characteristic luminescence of Eu 3+ . • Developing an Eu-MOF aerogel system with selective recognition, sensitive detection, and flexible features. • Investigating the fluorescence quenching mechanism of Eu-MOF. • Achieving a Cu 2+ detection limit of 0.775 × 10 −6 M with potential applicability in real polluted water samples. Given the hazards of metal ions and the difficulties in recycling and agglomeration of rare earth metal–organic framework (MOFs) powders, this study constructs a flexible aerogel fluorescence sensing platform based on dual-ligand Eu-MOF for highly sensitive detection of Cu 2+ . Eu-MOF exhibits outstanding fluorescence sensing performance by virtue of sharp emission bands, large Stokes shift and excellent photostability, combined with coordination environment modulation via dual ligands. Immobilizing such MOF into a 3D aerogel network can effectively overcome the drawbacks of poor processability, easy agglomeration and difficult recovery of MOF powders while preserving their intrinsic luminescence properties. The results show that Eu-MOF can be uniformly loaded onto the pore wall surface of PVA/k-CG/SA aerogel without significantly affecting its original luminescence properties. The obtained PVA/k-CG/SA/Eu-MOF aerogel exhibited a well-developed porous architecture and good mechanical robustness, after 10 cycles of compression at 60 % strain, the maximum compressive stress still reaches 12.08 kPa. Furthermore, the material exhibits the highest luminescence intensity when the mass ratio of Eu-MOF to DPA is 1:2, further increasing the Eu-MOF content leads to fluorescence attenuation due to concentration quenching effects dominated by electric dipole-electric dipole interactions. Under optimized detection conditions, this aerogel demonstrates a significant and excellent selective fluorescence quenching response to Cu 2+ , with a detection limit as low as 0.775 × 10 −6 M. This study provides a feasible strategy for constructing flexible, recyclable, and processable rare-earth MOFs macroscopic fluorescent sensing materials and demonstrates their application potential in environmental monitoring.
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MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 3
·184
·
IF 5.4
Tan Long,Xiao Rui,Wu Di,Hu Lianzhe,Zhang Yan,Qi Wenjing
A fast fluorescent dual-emission platform for sensitive detection of sodium dehydroacetate (SDHA) in food is established utilizing bimetallic organic frameworks (Eu@Zr-MOFs). Eu@Zr-MOFs show two fluorescent emissions at 430 nm and 616 nm under single excitation wavelength of 290 nm. Two peaks separated by 180 nm help to eliminate environmental interference and improve the accuracy. In the presence of SDHA, fluorescent intensity at 430 nm and 616 nm shows fluorescent quenching within 1 min. Fluorescent lifetime results show that fluorescent quenching is a static quenching mode. Fluorescent quenching may be ascribed to the diketone structure of SDHA coordinated with Eu 3+ and internal filtering effect. The logarithm of fluorescent intensity (lg I 430 nm * I 616 nm ) has linear relationship with the concentration of SDHA from 0.1 µM to 200 µM with a limit of detection of 31.6 nM. More conveniently, it also achieves visual detection of SDHA through fluorescent color by portable UV lamp and smartphone “color capture” mode. The platform is applied to detect SDHA in fermented and baked food samples. Thus it is an efficient and sensitive fluorescent ratio method for SDHA detection with fast response, high selectivity and accuracy. Graphical
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高影响因子
Frontiers in Chemistry
·
2022
·
IF 5.545
Zeng Zhijun,Shen Huaxiang,Gao Wei,Guo Qifeng,Chen Mengjie,Yan Xiaojun,Liu Hongning,Ji Yanhua
In this study, we use cytarabine anticancer drug to synthesize a new rare earth complex with Europium ion. The study work is an attempt to investigate luminescence and biological properties of the Eu-based coordination polymers of cytarabine (Eu-CP-Ara) anticancer drug which have been prepared by us. Eu-CP-Ara has luminescence properties with emission centering at about 619 nm excited with 394 nm. We study cytarabine and Eu-CP-Ara in vitro cytotoxicity. Cytotoxicity of Eu-CP-Ara against lung cancer cells (A549) could even be comparable to the inhibitory effect of cytarabine ligands, showing the advantage of antitumor activity. In addition, Eu-CP-Ara showed lower cytotoxicity to normal liver cells (L02). At the same, from the CLSM images, Eu-CP-Ara has successfully entered the A549 cell. Hence, Eu-CP-Ara can be used as a potential anticancer drug. Eu-CP-Ara may be an effective strategy for the tracking cytarabine against tumours and might impart better accurate treatment effect and therapeutic efficiency.
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PubMed
高影响因子
CRYSTENGCOMM
·
2022
·Vol. 24
·期 14
·2542-2550
·
IF 3.756
Ming-Yang Cao,Chun-Li Hu,Peng-Fei Chen,Qian Wang,Bing-Xuan Li,Yuan Lin,Jiang-Gao Mao
Three nonlinear optical materials Cd4REO(BO3)3 (RE = Sm, Eu, Tb) have been synthesized through high-temperature solid-state reactions. In their crystal structures, Cd(1)O8 and Cd(2)O6 polyhedra are interconnected via sharing edges and corners into a 3D anion framework with two types of tunnels based on 4- and 7-membered rings; the BO3 groups are grafted into the above-mentioned types, creating new tunnels based on Cd4B3 seven-membered rings, which are filled by RE3+ cations. Powder SHG measurements revealed that the Cd4REO(BO3)3 (RE = Sm, Eu, Tb) samples display SHG signals that are approximately 1.2, 5.6 and 1.5 times that of the KDP sample. In addition, Cd4EuO(BO3)3 and Cd4TbO(BO3)3 emit red and green light, respectively. The lifetime of the Eu(5D0) state for λex,em = 464, 610 nm in Cd4EuO(BO3)3 is measured to be about 1.43 ms whereas the lifetime of the Tb(5D4) state for λex,em = 376, 543 nm in Cd4TbO(BO3)3 is measured to be about 1.01 ms.
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高影响因子
OPTICAL MATERIALS
·
2020
·
IF 2.779
Aiqin Zhang,Zhi Wang,Weize Hong,Yining Zhang,Jiandong Guo,Yongchao Wang,Yanqin Miao,Husheng Jia,Hua Wang,Bingshe Xu
A novel bonded phosphor poly(Eu(TTA) 2 (phen)MAA-co-VA) (Eu-PVA, for short) was prepared employing the technology of coordination-polymerization-alcoholysis. The bonded Eu-PVA fluorescent nanofibers were prepared by electrospinning, having the initial decomposition temperature of 290 °C higher 51 °C than that of the doped nanofibers. A relationship is established between the fiber morphology and the fluorescence intensity of the bonded fiber Eu-PVA, predicting fluorescence quenching according to the morphological evolution. Compared with the corresponding fluorescent phosphors, both doped and bonded fluorescent fibers exhibit obvious fluorescence enhancement effects in that nanofibrosis increase the specific surface of the fibers and decrease the diffuse reflection and the light loss owing to the smoother surface of the fibers than that of the phosphors. Furthermore, security paper with both masking and security has been fabricated applying the bonded fluorescent nanofibers into pulp, being extended to the development of banknotes, bills, and securities.
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高影响因子
APPLIED SURFACE SCIENCE
·
2019
·
IF 5.155
Xin Zhong,Wen Liang,Zhipeng Lu,Baowei Hu
In this investigation, TpPa-1 were synthesized and exploited for radionuclides ions elimination. According to Langmuir model, at pH 6.5 and 298 K, the maximum adsorption quantity of TpPa-1 were 1194.07 mg(U(VI))/g and 1107.63 mg(Eu(III))/g, respectively. The superior adsorption performance could be attributed to: (i) a great quantity of heteroatom activated sites on the pore wall could conduct as cation receptors; (ii) the forming intramolecular C N … H … O hydrogen bonding in the network of TpPa-1, which was U(VI) and Eu(III) ions adsorption sites; (iii) hydrogen bonding could adjust the electron density of the complex and abate the total charge of radionuclides. The outcomes of this work suggest that TpPa-1 is a promising adsorbent, which is appropriate to enrichment and separation radionuclides from polluted wastewater.
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JOURNAL OF MOLECULAR STRUCTURE
·
2023
·
IF 3.8
Rui Shi,Pengcheng Hao,Zhongzhi Wang,Juan Zhang,Bo Li,Leijun Shen,Xin Qiao
In this work, we prepared a Carbazole-Benzene-Tripyridine ligand with a d -π-A structure and synthesized its corresponding Eu (III) and Tb (III) complexes. The structures of the complexes were analyzed by single crystal X-ray diffraction. It was surprisingly that the fluorescence emission intensity of the Eu(III) complex increases significantly once the solvent was added, indicating that the fluorescence could be activated by the solvent. However, it was confirmed that in the solid state, the complex molecules in the lattice were orderly arranged and there was a π-π stacking effect. The π-π stacking caused strong intermolecular interactions leading to emission quenching. The addition of solvent broke the π-π stacking and enhanced the fluorescence of the Eu(III) complex. The color of the fluorescence emission of the Eu(III) complex depended on the kind of added solvent. The results of nuclear magnetic resonance (NMR) and density functional theory (DFT) calculations suggested that the rotation of the C C single bond in the d -π-A structure ligand in different solvents caused a change in the spatial angle between the carbazole-benzene unit and the tripolypyridine unit in the ligand, thereby changing the excited state energy of the ligand. Hence, the varied emission colors of the complex reflect differences in the energy transfer efficiency of the ligand to rare earth ion. The solvent effect of the Eu(III) complex was then successfully applied in the rapid identification of specific alcohols.
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MICROCHIMICA ACTA
·
2018
·Vol. 185
·期 3
·1-10
·
IF 5.705
Wang Yan,Bian Feng,Qin Xiaofei,Wang Qianqian
A visible-light driven photoelectrochemical (PEC) aptasensor is described that is capable of detecting chloramphenicol (CAP). It is based on the use of a TiO 2 based nanorod array (NRA) sensitized with Eu(III)-doped CdS quantum dots. The NRA absorbs visible-light and while strongly depressing the recombination of photogenerated charges, thereby improving photo-to-current conversion efficiency. The introduction of Eu(III) ions promotes the charge transformation and utilization, and this results in a further increase of photocurrent. The NRA was employed as the photoactive material for the fabrication of a PEC aptasensor. CAP-binding aptamers were immobilized on a fluorine-doped tin oxide (FTO) electrode that was modified with the NRA. The aptasensor was applied to the determination of CAP by monitoring the decrease in photocurrent (at a typical voltage of 0 V) that is caused by the formation of the aptamer-CAP complex. Under optimal conditions, the response is linear in the 1.0 pM to 3.0 nM CAP concentration range, with a detection limit of 0.36 pM (at S/ N = 3). The method was applied to the determination of CAP in spiked milk samples where it gave satisfactory results.
Schematic presentation of the fabrication of a visible-light driven photoelectrochemical aptasensor based on the use of a TiO 2 nanorod array sensitized with Eu(III)-doped CdS quantum dots. It was applied to the determination of chloramphenicol with good selectivity and high sensitivity. TiO 2 NRA: TiO 2 nanorod array; FTO: fluorine-doped tin oxide; CdS:Eu 3+ QDs: Eu(III)-doped CdS quantum dots; BSA: bovine serum albumin; CAP: chloramphenicol
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高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2024
·
IF 4
Feifan Cheng,Yue Huang,Danling Mei,Lei Wang,Xueqin Zhao,Biao Huang
The visualization and accurate on-site detection of tetracycline and Cu 2+ residues in food are essential for maintaining food safety and public health. A novel poly (aspartic acid) Ratiometric fluorescent probe was designed for the sensitive visual detection of tetracycline (Tc) and Cu 2+ using the EDTA-Eu 3+ complex as the sensing unit and fluorescein dye as the internal standard. The fluorescence of Eu 3+ at 617 nm was turned on significantly by Tc via the “antenna effect” and can be quenched by Cu 2+ owing to the inner filter effect. The probes selectively detected Tc and Cu 2+ over a wide linear range, low LODs of 10 nM and 333 nM, respectively, were obtained. A smartphone APP and probe-loaded test paper were also assembled into a biomass-based portable sensor for visual point-of-use analysis. The fabricated sensors successfully monitored the Tc and Cu 2+ levels in milk, honey, and tap water samples, suggesting their broad applications in food safety monitoring and environmental analysis.
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高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Yuxin He,Hecun Zou,Xinhui Jiang,Yanrui Wei,Siqiao Li,Tong Wu,Zhengwei Zhang
Foodborne residue of carbendazim (CBZ) poses a major threat to human health. Here, we rationally designed a smartphone-assisted fluorescent sensor based on bimetallic-organic framework (Eu/Tb-MOF) for ultrasensitive and visual monitoring of CBZ. The Eu/Tb-MOF nanorods fabricated using Eu 3+ /Tb 3+ as metal nodes and homobenzoic tricarboxylic acid (H 3 BTC) as organic ligand exhibit superior optical properties. After adding CBZ, the strong orange fluorescence of Eu/Tb-MOF nanorods was suppressed by the inner filter effect (IFE). The linear ranges of the fluorescent sensor were 0.01–15 and 15–80 µg/mL, with a detection limit as low as 7.09 ng/mL. The analyses of CBZ residue in tomato and orange samples showed satisfactory recoveries of 99.32 %–101.97 % and low relative standard deviations of 0.87 %–3.44 %., verifying the practicality of the probe for CBZ. Notably, a simple and portable smartphone-assisted sensing platform based on the Eu/Tb-MOF nanorods was successfully constructed for quick, visual, and real-time monitoring of CBZ residue. This work provides an efficient onsite analytical method for assessment and warning-early of CBZ to safeguard food quality
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高影响因子
Analytical Methods
·
2024
·
IF 2.7
Huifeng Xu,Weihua Huang,Rui Pan,Ronglin Chen,Lili Wang,Yun Yu,Xihai Li,Xi Zhu
A stable dual-emission fluorescent system, R6G/Eu-MOF, was obtained by simple mixing Eu-MOF with fluorescent rhodamine 6G (R6G). This system not only achieved robust dual luminescence performance at 430 nm (Eu-MOF) and 555 nm (R6G) under single-wavelength excitation, but also endowed it significantly improved fluorescence stability. Orientin (OT), a bioactive traditional Chinese medicine (TCM) component, was found to efficiently quench the dual fluorescent emissions via the synergistic effect of dynamic quenching effect, photo-induced electron transfer and molecular interactions. Therefore, a rapid fluorescent assay for OT was developed based on the variations in fluorescence signals at 430 nm and 555 nm, as well as the alterations in the ratio between these two signals. This method can achieve highly sensitive determination of OT in the linear range of 1.1-220 µM, with a LOD of 0.26 µM at 430 nm and 0.16 µM at 555 nm (3σ/N). The R6G/Eu-MOF hybrid exhibits significantly lower detection limits and a broader linear range OT than either R6G or Eu-MOF alone. This work presents a simple strategy to improve the water stability of Eu-MOF, and also provides a rapid analysis of small molecule drug using a fluorescence approach based on dual-emission MOF hybrid system.
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高影响因子
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