CHEMOSPHERE
·
2022
·
IF 8.943
Yuhan Wang,Chang Liu,Chao Wang,Qing Hu,Longzhen Ding
Developing synergistic systems and taking environmental risks into account are two necessary aspects of being considered to remove persistent organic pollutants efficiently. Thus, a combined catalytic system uniting the Fenton-like process and simulated solar-light photocatalysis has been constructed. Moreover, a series of NiCo 2 O 4 /HP-UiO-66 catalysts (yNiCo-DUx) were also fabricated to improve tetracycline (TC) removal efficiency. The NiCo 2 O 4 nanoparticles (NPs) and hierarchically porous metal-organic frameworks (HP-MOFs) were synthesised using one-step calcination. The Z-scheme structure of the catalysts was confirmed by ESR, XPS, DRS, time-resolved PL (TR-PL) spectra and the quenching experiments. The NiCo 2 O 4 nanoparticles could be embedded and fixed into the defects of the MOF structure, and the leaching of toxic metals was also significantly suppressed. In the optimal reaction condition with 15NiCo-DU50, sunlight, and peroxymonosulfate (PMS), the total removal efficiency of TC could reach 98.5% within 8 min of irradiation, and the highest % RSE could reach 11.2%. Moreover, the corresponding reaction rate was 28.7, 3.6 and 1.3–10.2 times higher than photocatalysis, Fenton-like processes and other catalysts. Furthermore, the possible degradation mechanism, generation of reactive species and PMS excitation pathways were also investigated in depth. The present study sheds light on the fabrication of HP-MOFs based catalysts and the combination of various methods to eliminate organic pollutants.
研究领域:
环境科学
·
催化化学
✓ 已验证
DOI
高影响因子
Biofabrication
·
2025
·Vol. 17
·期 3
·035012
·
IF 8
Mengyuan Li,Jiaming Ge,Jingwen Yao,Yuanhao Zhang,Lin Ma,Zheng Li,Xiangli Han,Ming Liu,Fei Tian,Jing Zhao
Oral squamous cell carcinoma (OSCC) is the most common malignant tumor in the head and neck. Due to low bioavailability and passive targetability of anticancer drugs show great limitations in cancer therapy, the treatment of OSCC faces major challenges. Folic acid (FA) targeting can deliver anticancer drugs efficiently into the tumor environment, further enhance the anti-cancer efficacy. Herein, the nanoplatform based on UiO-66 that encapsulated with an effective FA targeting ligands and the pH-responsive polyethylene glycol (PEG) layer for the targeted delivery of berberine (Ber) is constructed for fighting against OSCC. The FA modification and controlled pH-responsiveness enable the targeted delivery of UiO-66/PEG-FA, which promotes the release of Ber and increases the cumulative intracellular Ber concentration, which both promote consumption of glutathione (GSH) and induced generation of reactive oxygen species (ROS), further stimulate the secretion of inflammatory factors (TNF-α and IL-1β). A comprehensive evaluation of in vitro and in vivo experiments show that UiO-66@Ber/PEG-FA promote autophagy and apoptosis of tumor cells by regulating the expression of Beclin-1, ATG13, BAX and Bcl-2, and effectively inhibit tumor growth. Overall, UiO-66@Ber/PEG-FA exhibit superior pH-responsiveness and targeted therapeutic efficiencies in vitro and vivo, it can serve as an approach for OSCC therapy.
研究领域:
肿瘤学
·
药剂学
·
纳米医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Jingling Gong,Bin Xiang,Ruirui Jin,Zhaoyang Li,Weimin Liu,Jian Li
Membrane fouling is a key challenge to the sustainable operation of oil–water separation membranes. Constructing a stable hydration layer on the membrane surface as an oil-fouling resistance barrier by modulating the physicochemical structure of the membrane is one of the most effective strategies. Herein, inspired by the petal structure in nature, Cu 3 (PO 4 ) 2 and UiO-66-NH 2 particles were combined by a self-assembly strategy to construct CUP (Cu 3 (PO 4 ) 2 /UiO-66-NH 2 /PVA) composite membranes with anti-fouling capability against viscous crude oil. Benefiting from the petal structure and abundant polar groups within the membrane, the as-prepared membrane could easily combine with water molecules to form a stable hydration layer, which acted as a barrier to hinder the oil contamination of the membrane. Further, the hierarchical flower-like structure was conducive to the improvement of the emulsion breaking rate and permeation flux of oil-in-water emulsions. After 60 min continuous cross-flow separation, the obtained CUP composite membrane still remained prominent separation efficiency (99.6 %) and permeate flux (4685.96 LMH/bar). In addition, the CUP composite membranes showed outstanding resistance to acid and alkali as well as abrasion. This study provides an effective method for the advancement of high-performance membranes with high flux and anti-fouling capability in the flied of oily wastewater treatment.
研究领域:
膜科学
·
材料工程
·
环境工程
·
分离技术
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2024
·
IF 4.1
Lingtao Liu,Lijian Wang,Jingxin Tan,Cong Yu,Junjie Bian,Xinbo Wang
Photocatalytic selective oxidation of furfural is a green, gentle way of preparing furoic acid. Photocatalytic oxidation effectively avoids the problems of difficult separation and high energy consumption in subsequent work-ups caused by the use of homogeneous oxidants. The photocatalytic process suffers from uncontrollable reactive oxygen species, resulting in low selectivity of the target product and excessive oxidation. Therefore, the K x -C 3 N 4 /UiO-66-NH 2 -Y catalyst was prepared by the mass proportion of UiO-66-NH 2 and K x -C 3 N 4 to form a heterogeneous structure, and the band gap width was adjusted to effectively avoid the formation of non-target strong reactive oxygen species ( OH). The results showed that: the aqueous 0.1 mM Na 2 CO 3 solution had an inhibitory effect on the non– target reactive oxygen species at room temperature; when the reaction time was 5 h and K 0.1 -C 3 N 4 /UiO-66-NH 2 -20, the furoic acid had the highest yield of 70.7, the target reactive oxygen species was confirmed by free radical capture experiments as O 2 – , and it was postulated that the reaction mechanism for the preparation of furoic acid by selective oxidation of furfural.
研究领域:
催化化学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Fan Yang,Hui-Hui Xie,Fan Du,Xiaomin Hou,Si-Fu Tang
Enzyme immobilization is an effective strategy for achieving efficient and sustainable enzyme catalysis. As a kind of promising enzyme-loading materials, the systematic research on zirconium based metal organic frameworks (Zr-MOFs) about immobilization performance at molecular level is still in its initial stage. In this work, UiO-66 was functionalized with various groups (-H, -NH 2 , -COOH, -OH, -2OH) for the immobilization of cytochrome c (Cyt c) and antioxidant enzyme catalase (CAT). Then the effects of surface-functionalized UiO-66 derivatives on the loading efficiency, enzyme stability and catalysis kinetics were systematically investigated. In addition, the affinity constants of Cyt c and CAT towards UiO-66-series MOFs carriers were also compared. The results have shown that hydroxyl group functionalized UiO-66 represents the highest enzyme loading capacity, enhanced activity and improved stability for Cyt c and CAT possibly due to high surface area and suitable microenvironments as well as enhanced affinity towards the enzymes provided by the introduction of a single hydroxyl group. Our research would foresee immense potential of MOFs in engineering biocatalysts.
研究领域:
材料科学
·
生物催化
·
化学工程
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry A
·
2024
·Vol. 12
·期 37
·25465-25474
·
IF 10.7
Yalin Niu,Peng Jiang,Tianying Guo
Developing high-performance artificial enzyme materials with practical applications in efficient catalytic hydrolysis detoxification of organophosphate (OP) nerve agents remains a formidable challenge. Herein, UiO-66-NH2-stabilized Pickering high internal phase molecularly imprinted polymer systems (MOFs@PHIPMIPs) were developed using OPs as template molecules. Thus, UiO-66-NH2-doped high-internal-phase MIP composites were obtained, which integrate MIPs and MOFs successfully, showing remarkable catalytic hydrolysis activity towards OPs. In addition, by introducing methyl methacrylate (MMA) during copolymerization, the MOFs@PHIPMIPs would effectively acquire pH buffering properties. The multi-porous composite catalysis system exhibits an exceptionally high detoxification efficiency towards dimethyl-4-nitrophenyl phosphate (DMNP) in pure water (kobs = 0.9162 min−1, t1/2 = 0.76 min). This work presents a new strategy for the preparation of artificial phosphatase materials with high-performance catalytic detoxification of OPs with great application prospects.
研究领域:
材料科学
·
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Zheng Dong,Yangyang Xin,Bowen Xiang,Baolu Cui,Ruilu Yang,Wenwu Zhou,Jianwei Liu,Jiadi Li,Shuangshuang Long,Libing Qian,Xinxin Che,Jinwen Fan,Zhiyuan Yang,Yaping Zheng,Dechao Wang
Porous liquids（PLs）are a new type of material that combines the permanent cavities of porous solids with the fluidity of liquids, and they have presented broad application prospects in gas capture and separation. However, non-covalent forces are introduced between pore generators and sterically hindered solvents in order to reduce the weak intermolecular forces that often lead to self-aggregation of pore generators. This will result in the formation of an interface layer with direct interactions between pore generators and sterically hindered solvents. Therefore, it is inevitable that the pores and adsorption sites of pore generators will be largely occupied and blocked, leading to a decrease in the sorption capacity of PLs. Herein, we propose a novel interface-protection strategy achieved by introducing a functional interface layer for preparing type III PLs, where UiO-66 is used as the pore generators. And then, SiO 2 is grown on the surface of UiO-66 via the tetraethyl orthosilicate (TEOS) hydrolysis process, thus obtaining a new pore generator UiO-66@SiO 2 with controllable layer thicknesses of SiO 2 . Next, PLs are constructed by using UiO-66@SiO 2 as the new pore generator and 1-butyl-3-methylimidazolium hexafluorophosphate (BMIMPF 6 ) as the sterically hindered solvent, respectively. Thus, the constructed SiO 2 layer transforms the direct interaction between pore generators and sterically hindered solvents, which can protect the internal adsorption sites and pore structures to a large extent. Notably, UiO-66@SiO 2 -PL demonstrates not only promising CO 2 sorption capacity but also excellent CO 2 /N 2 and CO 2 /CH 4 separations. More importantly, the proposed idea of the interface-protection strategy opens a new horizon for constructing PLs with superior separation performance considering the abundant libraries of pore generators and sterically hindered solvents.
研究领域:
材料科学
·
化学工程
·
气体分离
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
Chemosensors
·
2025
·Vol. 13
·期 9
·340
·
IF 3.7
Hongmei Gao,Yourong Zhao,Yuhong Xie,Yiying Wang,Jie Che,Daojiang Gao,Zhanglei Ning
In this study, a novel carbon quantum dots-functionalized UiO-66 composite was successfully prepared via the post-synthetic modification method and further developed into a ratiometric fluorescent probe for detecting uric acid. The composite demonstrates excellent structural and luminescent stability under challenging environmental conditions. As a ratiometric fluorescent probe, its recognition principle relies on the ratio of response signals from two different fluorescent emission centers in the composite. In the presence of uric acid, the fluorescence emission intensity at 430 nm from CDs did not change significantly. However, the fluorescence intensity at 545 nm from Tb3+ions decreased remarkably. This material was evaluated for its capacity to sense urinary components and was shown to specifically recognize uric acid over a wide concentration range (0~5 × 10−3M). Moreover, it exhibited strong resistance to interference and high sensitivity in uric acid detection. The detection limit (LOD) was determined to be 0.102 μM through quantitative analysis. The sensing mechanism was validated through spectral overlap and fluorescence lifetime analysis, which can be attributed to the fluorescence resonance energy transfer (FRET) process. This ratiometric fluorescent probe provides an efficient and reliable strategy for detecting the biomarker uric acid.
研究领域:
分析化学
·
生物医学工程
·
纳米医学
·
分子诊断
·
生物传感器
·
临床检验
✓ 已验证
产品关联
DOI
高影响因子
COMPOSITES COMMUNICATIONS
·
2024
·
IF 6.5
Yuanya Zhang,Yu He,Wen Ma,Yanlin Zhu,Yuxiang Liu,Junya Yuan,Xuehu Men
Despite epoxy composites being used in a wide range of applications, it remains a great challenge to solve the defect of high brittleness and poor wear resistance for real engineering applications. Nanomaterials enhance fracture toughness and provide superior antifriction and wear resistance for epoxy matrix materials. In this work, a late-model ANFs/MXene/UiO-66-NH 2 hybrid aerogel (AMU) with 3D layered and “mortar-brick” multi-hole structure was devised via solution impregnation and hydrothermal in situ growth processes. MXene and UiO-66-NH 2 were uniformly anchored to the surface of the ANFs aerogel backbone due to hydrogen bonding forces and electrostatic adsorption. The acquired AMU-EP composites exhibited excellent thermal conductivity owing to an efficient three-dimensional network of thermal conductive pathways inside the epoxy matrix. Moreover, the efficient synergistic effect of AMU components formed a high-quality transfer film on the surface of steel balls during the friction process, which was important for enhancing the tribological properties of AMU-EP.
研究领域:
材料科学
·
纳米技术
✓ 已验证
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Yu Yang,Meng Du,Jiaxin Liang,Qian Xu,Wei Liu,Ang Li
The flow-through electroactive membrane adsorption method has been proved to be a promising strategy to enrich low-concentration phosphate. However, the challenges of selective adsorption of phosphate and poor regeneration restrict its industrial application. Here, this study proposed a novel bimetallic Mg-UiO-66@rGO electrode material through the introduction of Mg(II) into UiO-66, which possessed remarkable adsorption selectivity and optimal reproducibility among the reported electrode materials. The maximum phosphate adsorption capacity of Mg-UiO-66(13)@rGO (Zr/Mg = 3:1) was 62.81 mg⋅g −1 at 3.2 V. Furthermore, it maintained the excellent adsorption properties in the presence of all competitive anions and after 30 times of continuous adsorption–desorption. In actual wastewater, Mg-UiO-66(13)@rGO still represented excellent adsorption kinetics of 0.51 mg⋅(g⋅min) −1 and equilibrium adsorption capacity of 61.2 mg⋅g −1 . The superior selectivity of Mg-UiO-66@rGO was attributed to the establishment of coordinative unsaturated metal sites (CUMSs), thus increasing the adsorption sites. The synergic effect of electric field facilitates the breaking and formation of coordination bonds between charged ions and deeper binding sites, boosting the adsorption–desorption ability. Notably, the structural stability is also a key factor in promoting repeated material regeneration. This study advances electrode material to a new level by introducing CUMSs and bimetallic synergies.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
COMPOSITES PART B-ENGINEERING
·
2019
·
IF 6.864
Wenwen Guo,Shibin Nie,Ehsan Naderi Kalali,Xin Wang,Wei Wang,Wei Cai,Lei Song,Yuan Hu
The SiO 2 @metal organic framework (Universitetet i Oslo-66, UiO-66) core–shell microspheres were constructed through covalent linkage between amine groups in UiO-66-NH 2 and epoxy groups on the surface of silica . The morphology and size of the SiO 2 @UiO-66 core–shell microspheres could be simply controlled by tuning the ratio between UiO-66-NH 2 and epoxy terminated silica (E-SiO 2 ). As observed by TEM , the SiO 2 @UiO-66 hybrids showed better dispersion state within epoxy matrix compared to either E-SiO 2 or UiO-66-NH 2 . The incorporation of SiO 2 @UiO-66 hybrids slightly promoted the thermal degradation of the resultant epoxy composites but improved residual yield. The dynamic mechanical analysis results indicated that the SiO 2 @UiO-66 hybrids slightly increased the glass transition temperature and the modulus. The SiO 2 @UiO-66 hybrids exhibited higher efficiency in reducing the heat release rate and the smoke production rate compared to either E-SiO 2 or UiO-66-NH 2 . The influence of the component ratio in SiO 2 @UiO-66 on flame retardancy of the epoxy composites was also studied by cone calorimeter . Specifically, the SiO 2 @UiO-66 hybrid with medium ratio (SiO 2 @UiO-66-2) exhibited maximum reduction in peak heat release rate (−31%), total heat release (−23%) and total smoke production (−16%). The char residues were investigated by the Fourier transform infrared spectra, scanning electron microscopy and X-ray photoelectron spectroscopy, which demonstrated that the enhanced flame retardancy of EP/SiO 2 @UiO-66-2 was attributable to the continual morphology and high thermal resistance originated from the presence of the silicon and zirconium complex. These favorable characteristics including high flame retardant efficiency and good smoke suppression make SiO 2 @UiO-66 hybrids promising for flame retardant polymers application .
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Zixu Wang,Linna Han,Qing Xia,Wanfang Feng,Songtao Li,Liyan Liu
Enrichment and quantification of sugar phosphates (SPx) in biological samples are of great significance in biological medicine. In this work, a magnetic nanoscale metal–organic framework composite, Fe3O4@UiO-66-NO2, was synthesized and utilized as a high-capacity adsorbent for the enrichment of SPx in biological samples. Fe3O4@UiO-66-NO2 exhibited a high specific surface area (310.02 m2/g), a suitable pore size (3.47 nm), and strong magnetism (14.99 emu/g), enabling convenient separation and recovery. Experimental results demonstrated that Fe3O4@UiO-66-NO2 exhibited excellent adsorption performance for five types of SPx, achieving complete adsorption within 6 min at a dosage of 200 μg, and the adsorption process exhibited pH tolerance. The adsorption isotherm result indicated that the maximum adsorption capacities for different SPx ranged from 234.06 mg/g to 403.24 mg/g. Adsorption mechanisms using X-ray photoelectron spectroscopy, FT-IR, and density functional theory revealed multiple interactions, such as coordination and hydrogen bonding, and contributed to the adsorption process. A magnetic nanoscale-dispersive solid-phase extraction protocol was developed based on a Fe3O4@UiO-66-NO2 for rapidly enriching SPx from biological samples. The protocol allowed for SPx detection over a wide linear concentration range, low limits of detection (0.001–0.02 ng/mL), high precision (<7.88%), and good accuracy (82.56%–119.66%). This protocol was successfully applied to real blood samples, prefiguring the great potential of magnetic MOFs for the enrichment and detection of SPx in biological samples.
研究领域:
分析化学
·
材料科学
·
纳米技术
·
生物化学
·
环境科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）