Biomass Conversion and Biorefinery
·
2021
·Vol. 13
·期 10
·9249-9264
·
IF 4.987
Chen Bing-Hui,Wang Zi-Qi,Jin Zi-Chu,Gou Ze-Chang,Tang Shan-Shan,Yu Xiao-Xiao,Chen Huan,Chen Guang,Su Ying-Jie
Corn stover is the abundant biowaste that can be utilized to produce biofuels and high value-added biological products. However, the complex structures of lignocellulose, on the other hand, are highly resistant to subsequent transformations. To promote enzymatic saccharification of corn stover, green and safe phosphotungstic acid was used to pretreat corn stover. Using a single-factor experiment and response surface approach, the influence of different pretreatment variables such as temperature, phosphotungstic acid concentration, pretreatment time, and solid-to-liquid ratio on the pretreatment effect was investigated. The best conditions were 126 ℃, 1.33%, 45 min, and 1:14, respectively, and the cellulose conversion rate was the greatest at 70.61% combined phosphotungstic acid and cellulase, raised by 171.99% when compared to the raw corn stover. Phosphotungstic acid was demonstrated to degrade both hemicellulose and lignin, yielding 25.89 mmol/L xylose. Phosphotungstic acid pretreatment samples were found to be more porous, with cellulase adsorption capacity increased from 161.56 to 245.70 mg/g biomass. CrI/cellulose was found to decrease from 1.09 to 0.77, indicating significant chemical alterations in corn stover functional linkages. These findings suggest that phosphotungstic acid enhances saccharification by altering the structure and chemistry of corn stover. The combination of phosphotungstic acid and cellulase will give an efficient approach for increasing the saccharification of cellulose.
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高影响因子
MICROCHIMICA ACTA
·
2021
·Vol. 188
·期 10
·1-10
·
IF 5.833
Ding Yanru,Cheng Yuqi,Hao Baoqin,Zhu Lin,Zhang Nan,Zhao Bing,Tian Yuan
A versatile surface-enhanced Raman scattering (SERS) assay has been established that can realize rapid and sensitive determination of sildenafil (SIL) and pioglitazone hydrochloride (PIO) adulteration in healthcare products. Metal–organic frameworks-silver nanoparticles (MOFs-AgNPs) with SERS activity were successfully prepared via in situ synthesis AgNPs on the MOFs surface. By virtue of the adsorptivity of MOFs, the MOFs-AgNPs could effectively concentrate the drug molecules on the electromagnetic enhancement areas of AgNPs. Moreover, the MOFs-AgNPs substrate exhibited more sensitive SERS activity than classical AgNPs with linear range of 1.0 × 10 –7 –1.0 × 10 –5 mol L −1 for SIL and 8.0 × 10 –7 –3.0 × 10 –5 mol L −1 for PIO and limit of detection (LOD) of 4.8 × 10 –8 mol L −1 for SIL and 1.4 × 10 –7 mol L −1 for PIO. The designed method realized the determination of SIL and PIO in commercial tablets and healthcare products with recoveries of 93.8–108.0% and 93.0–104.0%, respectively, with relative standard deviation (RSD) of 2.7–4.1% and 2.2–4.2%, respectively. The present system displayed little interference effect on determination. This work provides a multifunctional route for the determination of other drugs via the SERS technology. Graphical abstract
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PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2021
·Vol. 56
·期 36
·19955-19968
·
IF 4.22
Lu Haitao,Shi Huili,Sun Lei,Wang Keli,Zhang Xia
In this work, cobalt ferrite (CoFe 2 O 4 ) was used to modify self-lubricating boron nitride nanosheets (BNNs), followed by the treatments of stearic acid to fabricate a superhydrophobic and magnetic composite fillers: STA-CoFe 2 O 4 -BNNs. Under a magnetic field, the STA-CoFe 2 O 4 -BNNs fillers can be well-aligned to form a denser arrangement in the polydimethylsiloxane (PDMS) matrix, which prevented heat transfer to underlying materials, and prepared hydrophobic and flame retardant composite materials (i.e., STA-CoFe 2 O 4 -BNNs/PDMS). The peak smoke production release and the total smoke rate of the oriented STA-CoFe 2 O 4 -BNNs/PDMS were reduced by 35.8% and 44.7%, respectively, compared with those of the pure PDMS. The obtained STA-CoFe 2 O 4 -BNNs/PDMS shows exceptional superhydrophobic durability under knife-scratch, high temperature, corrosive liquids, and UV irradiation.
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高影响因子
CELLULOSE
·
2021
·Vol. 28
·期 16
·10127-10141
·
IF 5.044
Qi Benkun,Wang Zhenwu,Luo Jianquan,Wan Yinhua
As a cheap, biodegradable, and nontoxic chemical, choline chloride (ChCl) is widely used in animal feed. In this study, acid and alkali catalyzed ChCl pretreatments of corn stover (CS) were investigated. Compared with single aqueous ChCl pretreatment, H 2 SO 4 acidified aqueous ChCl pretreatment was more effective in removing lignin (69.5%) and xylan (84.9%). NaOH alkalified aqueous ChCl pretreatment demonstrated better performance of delignification (76.8%) but weaker capability of removing xylan (46.2%) than acidified aqueous ChCl pretreatment. Following enzymatic digestibility of pretreated CS, glucose yield from acidified ChCl pretreatment was 72.1%, significantly lower than that of alkalified ChCl pretreatment (89.4%). However, the highest glucose yield of 98.6% resulted from solitary alkali pretreatment. Correlation studies between change in physico-chemical properties of pretreated solids and corresponding enzymatic digestibility indicated high delignification and bigger cellulose crystallite size were mainly responsible for high enzymatic hydrolysis efficiency. Additionally, the properties of extracted lignin from single and combined pretreatments with ChCl and alkali or acid were analyzed. Acidified ChCl pretreatment increased, whereas alkaline ChCl pretreatment decreased molecular weight and phenolic hydroxyl groups of separated lignin in comparison to individual acid and alkali pretreatment. These findings would provide useful information in understanding biomass pretreatments with aqueous ChCl.
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高影响因子
JOURNAL OF POROUS MATERIALS
·
2021
·Vol. 29
·期 1
·103-110
·
IF 2.496
Yang Yeqing,Liao Yingling,Liu Naiwang,Shi Li,Meng Xuan
β Zeolite/bentonite composite was synthesized by simple kneading as catalyst for condensation reaction of aniline to diphenylamine. The experiment which was conducted at 320 °C under 2 MPa with a liquid hourly space velocity (LHSV) of 2 h −1 showed that the Hβ zeolite loading 25% clay exhibited the highest activity (9.9% aniline conversion) and selectivity. Pilot experiments (315–320 °C, 2 MPa, LHSV of 0.20–0.22 h −1 ) have also confirmed that the catalyst had good stability. The crystalline structure, acidic property and textural property of the catalysts were characterized by XRD, Py-IR, N 2 adsorption–desorption. Moreover, according to the thermodynamic analysis, the condensation of aniline to diphenylamine is an exothermic reaction, indicating that too high temperature operation is unfavorable for the reaction. The studied β zeolite/bentonite composite is of promising efficiency in condensation of aniline to diphenylamine.
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高影响因子
JOURNAL OF ELECTRONIC MATERIALS
·
2021
·Vol. 50
·期 11
·6426-6437
·
IF 1.938
Zhang Chao,Sun Huajun,Zhu Quanyao
In this paper, two methods (magnetic stirring and mechanical ball milling) were used to modify the surface of lead zirconate titanate (PZT) particles. Then, poly(vinylidene fluoride) (PVDF)/PZT piezoelectric films were prepared by extrusion casting and solvent casting. We investigated the mechanical, dielectric, ferroelectric, and piezoelectric properties, as well as the breakdown strength of the PVDF/PZT films. We found that adding PZT particles improved the mechanical stability of the films under variable temperature conditions. Modification by the UP-105 titanate coupling reagent further improved the combination and dispersion of PZT@105 particles in PVDF. The films prepared by extrusion casting showed improved properties in terms of density, dielectric constant, breakdown strength, and piezoelectric coefficient. The piezoelectric coefficient ( d 33 ) of the PVDF/PZT@105 composite film (with 25 wt.% PZT@105) prepared by extrusion casting reached 35 pC/N, and the electromechanical strain ratio was almost 1.6%, which is higher than that of piezoelectric ceramics.
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高影响因子
IONICS
·
2021
·Vol. 27
·期 11
·4885-4895
·
IF 2.817
Qu Yuning,Yu Zehui,Wei Dan,Chen Ling,Zheng Zhe,Xiao Ningru,Wang Lili,Yu Jianguo
Pt-based materials have widely been explored as hydrogen evolution reaction (HER) catalysts, but the high cost of Pt catalyst limits its application in HER. Therefore, we report a platinum/polyvinyl-alcohol (Pt x -PVA) catalyst with high catalytic activity and low Pt loading. Pt x -PVA catalysts with a uniform distribution of the Pt nanoparticles (NPs) have successfully been synthesized by a simple one-step hydrothermal method. The size and morphology of Pt NPs can be easily adjusted by changing the amount of Pt precursor, easy to pick out the sample with the best performance. Among them, the Pt 1.88 -PVA catalyst exhibits the best electrocatalytic activity for HER in 0.5 M H 2 SO 4 solution. An overpotential of 34 mV on Pt 1.88 -PVA catalyst is obtained at a current density of −10 mA cm −2 , which is slightly better than the overpotential of the commercial Pt/C (42 mV). Similarly, the Tafel slope of 31 mV dec −1 on the Pt 1.88 -PVA catalyst indicates that the HER process is the Volmer-Tafel mechanism. However, the Pt loading of the Pt 1.88 -PVA catalyst is 18.8% times lower than that of the commercial Pt/C. Furthermore, the Pt x -PVA catalysts exhibit an excellent stability and durability. This is due to the coating effect of PVA for Pt NPs, which limits the migration and agglomeration of Pt NPs. This study provides a new approach for reducing the Pt load in Pt-based catalyst in the field of electrochemistry.
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高影响因子
Science China-Chemistry
·
2021
·Vol. 64
·期 10
·1770-1777
·
IF 9.445
Xu Mengdi,Hua Luqin,Gong Lihao,Lu Jianlei,Wang Jinhui,Zhao Chuanzhuang
The interaction between the aggregation-induced emissive (AIE) luminogens (AIEgen) and the polymer is the key scientific question in the design of functional AIE hydrogels. In this study, we report the AIE behavior of a poly(acrylic acid) (PAAc) and poly(acrylamide) (PAAm) interpenetrating network (IPN) hydrogel doped with tetra-cationic tetraphenylethene (TCTPE). The cationic AIEgen can bind with PAAc through ionic interaction, while PAAc and PAAm chains can associate with each other through hydrogen-bonds (H-bonds). These two interactions can restrict the intramolecular rotation and thus activate the luminescence of the AIEgen. The PAAc-PAAm H-bonds can be broken by increasing temperature or pH, restoring the intramolecular rotation of the AIEgen and quenching the fluorescence of the hydrogel. Therefore, the TCTPE-doped IPN hydrogel is designed as temperature- and pH-sensitive displayers which can record information imprinted by photo-printing or iono-printing with good switchability and reversibility. Another application of this TCTPE-doped hydrogel is demonstrated as a luminescent soft actuator, which has fast shape deformation and editable fluorescence pattern. The above results reveal a pathway to tune the emission behavior through tuning polymer-polymer and polymer-AIEgen interactions, which may inspire new design strategies of aggregation-induced emissive polymers and broaden their applications.
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JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
·
2021
·Vol. 26
·期 7
·793-808
·
IF 3.358
Chen Jincan,Deng Yuanyuan,Wang Jie,Chen Suxiang,Peng Fa,He Xuerong,Liu Meijun,Luo Hui,Zhang Jingjing,Chen Lanmei
Abstract Two new cyclometalated Ru(II)-β-carboline complexes, [Ru(dmb) 2 (Cl-Ph-βC)](PF 6 ) (dmb = 4,4′-dimethyl-2,2′-bipyridine; Cl-Ph-βC = Cl-phenyl-9H-pyrido[3,4-b]indole; RuβC-3 ) and [Ru(bpy) 2 (Cl-Ph-βC)](PF 6 ) (bpy = 2,2′-bipyridine; RuβC-4 ) were synthesized and characterized. The Ru(II) complexes display high cytotoxicity against HeLa cells, the stabilized human cervical cancer cell, with IC 50 values of 3.2 ± 0.4 μM ( RuβC-3 ) and 4.1 ± 0.6 μM ( RuβC-4 ), which were considerably lower than that of non-cyclometalated Ru(II)-β-carboline complex [Ru(bpy) 2 (1-Py-βC)] (PF 6 ) 2 (61.2 ± 3.9 μM) by 19- and 15-folds, respectively. The mechanism studies indicated that both Ru(II) complexes could significantly inhibit HeLa cell migration and invasion, and effectively induce G0/G1 cell cycle arrest. The new Ru(II) complexes could also trigger apoptosis through activating caspase-3 and poly (ADP-ribose) polymerase (PARP), increasing the Bax/Bcl-2 ratio, enhancing reactive oxygen species (ROS) generation, decreasing mitochondrial membrane potential (MMP), and inducing cytochrome c release from mitochondria. Further research revealed that RuβC-3 could deactivate the ERK/Akt signaling pathway thus inhibiting HeLa cell invasion and migration, and inducing apoptosis. In addition, RuβC-3 -induced apoptosis in HeLa cells was closely associated with the increase of intracellular ROS levels, which may act as upstream factors to regulate ERK and Akt pathways. More importantly, RuβC-3 exhibited low toxicity on both normal BEAS-2B cells in vitro and zebrafish embryos in vivo. Consequently, the developed Ru(II) complexes have great potential on developing novel low-toxic anticancer drugs. Graphic Abstract
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PubMed
高影响因子
RARE METALS
·
2021
·Vol. 41
·期 2
·406-414
·
IF 4.003
Jiang Xiao-Huan,Duan Ying-Nan,Tian Yu,Chen Meng,Li Mao-Kun,Liu Huan-Huan,Yang Wan-Liang,Tian Meng-Kui
In this paper, a visible light-responsive Sn 2+ and N co-doped TiO 2 photocatalyst was prepared by facile one-pot hydrothermal method. All as-prepared samples were characterized in detail by a series of characterization approaches. The results showed that the Sn 2+ and N elements were co-doped into TiO 2 , while the catalyst still maintains anatase crystal structure and gets irregular little nanocluster in diameter of 9–10 nm with higher specific surface area. The absorption edge of Sn 2+ and N co-doped TiO 2 extends to the visible light region. Compared with Sn 2+ -doped TiO 2 and N-TiO 2 , the absorption edges have obvious red-shift of about 50 and 70 nm, respectively. The synergistic effect of O 2p-N 2p and O 2p-Sn 5s hybridization to form impurity levels is the main reason for the red-shift. The hydrogen production performance of the Sn 2+ and N co-doping TiO 2 ( n (N)/ n (Ti) = 1) catalyst reached the maximum value of 0.37 mmol·h −1 ·g −1 under visible light, which is higher than that of N-doped TiO 2 and Sn 2+ -doped TiO 2 singly. This result is due to the wider visible light region-responsive ability of Sn 2+ and N co-doped into TiO 2 . Furthermore, mild hydrothermal methods will not make the Sn 2+ oxidized to Sn 4+ , which make the catalysts still maintain high photocatalytic performance. This work provides a simple and mild method for the preparation of dual-element co-doped TiO 2 with high crystallinity, excellent performance and broad application prospects. Graphic abstract
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高影响因子
CELLULOSE
·
2021
·Vol. 28
·期 17
·10999-11011
·
IF 5.044
Si Rongrong,Wu Chaojun,Yu Dongmei,Ding Qijun,Li Ronggang
Abstract In this study, environmentally friendly TEMPO-oxidized cellulose nanofiber (TO-CNF)/polyvinyl alcohol (PVA)/polyethyleneimine (PEI) nanoparticles were obtained by assembling PEI into TO-CNF/PVA aerogel, which was prepared by freeze-drying method with the help of glutaraldehyde. FTIR results showed that PEI likely assembled into the TO-CNF/PVA aerogel due to appearances of bending vibration of the TO-CNF/PVA/PEI nanoparticles at 1615 cm −1 . BET results further demonstrated that PEI have successfully assembled into the aerogel since the specific surface area (22.93 m 2 /g) of TO-CNF/PVA /PEI nanoparticles was lower than that (56.37 m 2 /g) of TO-CNF/PVA aerogel. SEM results also showed that PEI could obviously regulate the morphology of TO-CNF/PVA aerogel. TGA indicated that TO-CNF/PVA/PEI nanoparticles were structurally stable at 216.4 °C. The adsorption kinetics of the TO-CNF/PVA/PEI nanoparticles for copper ion (Cu 2+ ) removal presented good correlations with the Pseudo-second-order kinetic and Langmuir model ( R 2 > 0.99). Its maximum adsorption capacity for Cu 2+ according to Langmuir model was 156.8 mg/g. The adsorption equilibrium could reach in near one hour, and the adsorption efficiency could still maintain more than 80% after 3 cycles. Graphic abstract
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高影响因子
CELLULAR & MOLECULAR BIOLOGY LETTERS
·
2021
·Vol. 26
·期 1
·1-16
·
IF 5.787
Xing Ying,Liu Yang,Qi Zhong,Liu Zhengrong,Wang Xin,Zhang Hongyi
Background Hepatocellular carcinoma (HCC) is now the second leading cause of cancer death worldwide and lacks effectual therapy due to its high rate of tumor recurrence and metastasis. The aim of this study was to investigate the effects of L antigen family member 3 (LAGE3, a member of the LAGE gene family involved in positive transcription) on the progression of HCC. Methods The expression of LAGE3 was detected by quantitative real-time polymerase chain reaction. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, colony formation assay, EdU, and cell cycle analysis assay were employed to evaluate the proliferation of HCC cells. Annexin V-FITC/PI and TUNEL assay were used to assess the apoptosis rate of HCC cells. Wound healing and transwell assay were used to investigate the migration and invasion of HCC cells. A xenograft model of HCC was established with 2 × 10 6 Hep3B or SK-HEP1 cells to investigate the in vivo effects of LAGE3. Then, the protein levels of LAGE3, p-p38, p-38, c-Jun N-terminal kinase (JNK),p-JNK, extracellular signal-regulated kinase (ERK), and p-ERK were detected by western blot. Results We found that LAGE3 was upregulated in HCC tissues compared to adjacent tissues, and its high expression was correlated with poor overall survival by bioinformatics analysis. Next, we manually regulated the expression of LAGE3 in HCC cells. The knockdown of LAGE3 inhibited the proliferation of HCC cells by arresting the cell cycle in G1 phase. Also the downregulation of LAGE3 inhibited cell migration and invasion and induced apoptosis of HCC cells, while overexpression of LAGE3 promoted the malignant phenotypes of HCC. These results were further confirmed by the in vivo growth of HCC xenografts and the inhibition of apoptosis of HCC tumor cells. Furthermore, we found that LAGE3 exerted cancer-promoting effects by potentiating the JNK and ERK signaling pathway. An ERK inhibitor (10 μM SCH772984) or JNK inhibitor (25 μM SP600125) repressed the upregulated LAGE3-induced proliferation, migration, and invasion of HCC cells. Conclusions LAGE3 enhanced the malignant phenotypes of HCC by promoting the JNK and ERK signaling pathway.
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高影响因子
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