WATER AIR AND SOIL POLLUTION
·
2020
·Vol. 231
·期 6
·1-15
·
IF 1.9
Cheng Sha,Zeng Wei,Liu Xiaomei,Zhao Junji,Qiu Xueyan,Lei Ziqiang
Hydroxypropyl cellulose-g-poly (acrylicacid-co-2-acrylamido-2-methyl-1-propane sulfonic acid)/laterite (HPC-g-P (AA-co-AMPS)/laterite) with excellent water (salt) absorbency, water retention performance, re-swelling property, and fast water absorption rate was prepared by free-radical polymerization. The structure and morphology of the synthetic materials were characterized by FTIR, SEM, and TGA. The water absorbency of superabsorbent resin in different salt solutions was studied, and it was proved that the superabsorbent resin was more sensitive to salt solutions. The swelling kinetic mechanism of superabsorbent resin was explained by pseudo-second-order swelling kinetic model. The effects of the ratio of laterite to loess on water evaporation and the content of superabsorbent resin on soil water evaporation and shrinkage of soil crust were studied.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2020
·Vol. 27
·期 24
·30844-30852
·
IF 3.056
Hu Xingru,Qi Junwen,Lu Rui,Sun Xiuyun,Shen Jinyou,Han Weiqing,Wang Lianjun,Li Jiansheng
Efficient and selective removal of antibiotics from wastewater is quite important but challenging. In this work, the nitrogen-doped mesoporous carbon nanospheres (NMCN) with different pore size (from 2.67 to 4.62 nm) were successfully prepared by changing the hydrothermal condition, and their removal performance on tylosin was evaluated. The adsorption experimental data were fitted well with the pseudo-second-order kinetic model. Besides, Langmuir isotherm model could better describe the adsorption process. Notably, the NMCN with medium pore size (3.36 nm) exhibited the highest adsorption capacity (1333 mg g −1 ), which was 24% and 14% higher than that of NMCNs with smaller and larger pore size, respectively. In order to study the adsorption mechanism, the mesoporous carbon nanospheres without N-doped was prepared, and the comparison of nitrogen adsorption-desorption isotherms was conducted. The result proved that in addition to the modified surface property, large specific surface area, and high pore volume, the pore size could precisely influence the adsorption performance of the proposed adsorbent. Furthermore, the proposed NMCN material possessed a selective adsorbing ability toward tylosin in the presence of tetracycline. Clearly, the NMCN was a promising alternative to be used as high efficient and selective adsorbent in practical environment pollution treatment, especially in large-size molecule adsorption.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2020
·Vol. 27
·期 22
·27663-27673
·
IF 3.056
Liu Yuan-zhen,Xu Qi-yan,Guo Rui-tang,Duan Chao-peng,Wu Gui-lin,Miao Yu-fang,Gu Jing-wen
The Cu/TiO 2 catalysts with the addition of Eu were developed by the sol-gel way for the selective catalytic reduction (SCR) of NO x by NH 3 . Activity tests revealed that CuEu/TiO 2 -0.15 catalyst showed the optimal de-NO x performance in a wide temperature range (150–300 °C), along with an admirable SO 2 tolerance. According to characterization analysis, the relationship between the NH 3 -SCR performance and physicochemical characters of samples was explored. The adjunction of Eu on Cu/TiO 2 catalyst can contribute to the formation of a large amount of Cu 2+ , adsorbed oxygen, and acid sites on the catalyst surface. Moreover, the Eu addition on Cu/TiO 2 is favorable to the generation of activated NO x and NH 3 substances adsorbed on the catalyst surface, which would conduce to the NH 3 -SCR process by Langmuir-Hinshelwood (L-H) mechanism effectively.
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高影响因子
OBESITY SURGERY
·
2020
·Vol. 30
·期 9
·3435-3443
·
IF 3.412
Sun Kangyue,Wang Jing,Lan Zhixian,Li Ling,Wang Yadong,Li Aimin,Liu Side,Li Yue
Purpose Endoscopic sleeve gastroplasty (ESG) has been suggested to be effective for treating obesity and its related non-alcoholic fatty liver disease (NAFLD). A small molecule named CY-09 is the selective inhibitor of the NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome. We aim to investigate whether a surgery imitating ESG combined with CY-09 is more effective for treatment of obesity and NAFLD in a mouse model. Material and Methods Forty mice were randomly divided into a control group ( n = 5) and an NAFLD group ( n = 35) fed by high-fat diet (HFD). The NAFLD mice were randomly assigned to the following groups at the timepoint of 19 weeks: (1) sham surgery; (2) surgery; (3) the combination of surgery with CY-09 injection. NAFLD activity score (NAS) was used for histological evaluation of steatosis. We also detected fasting glucose and insulin to measure the homeostasis model assessment of insulin resistance (HOMA-IR). Results HFD resulted in significant obesity and metabolic disorders, indicating successful modelling of obesity and NAFLD. The combination therapy resulted in significantly lower body weight than surgery alone at the end of the 8-week follow-up (40.4 ± 4.8 vs. 45.0 ± 2.2 g, P = 0.025). Furthermore, more dramatic improvements in HOMA-IR (5.8 ± 1.1 vs. 12.2 ± 2.1 mmol mIU L −2 , P = 0.036) and NAS (4.5 ± 1.3 vs. 8.0 ± 1.8, P = 0.006) were also observed in the combination group. Conclusions Surgery imitating ESG combined with CY-09 reduces body weight, improves insulin resistance and alleviates hepatic steatosis. The combination therapy may be a promising method for treating obesity and NAFLD.
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Journal of Advanced Ceramics
·
2020
·Vol. 9
·期 2
·193-203
·
IF 2.889
Liu Junwen,Zhou Xiaobing,Tatarko Peter,Yuan Qin,Zhang Lan,Wang Hongjie,Huang Zhengren,Huang Qing
The SiC/Al 4 SiC 4 composites with the improved mechanical properties and thermal conductivity were fabricated by the in-situ reaction of polycarbosilane (PCS) and Al powders using spark plasma sintering. The addition of 5 wt% yttrium (Y) sintering additive was useful to obtain fully dense samples after sintering at a relatively low temperature of 1650 °C, due to the formation of a liquid phase during sintering. The average particle size of the in-situ formed SiC was ~300 nm. The fracture toughness (4.9 MP·m 1/2 ), Vickers hardness (16.3 GPa), and thermal conductivity (15.8 W/(m·K)) of the SiC/Al 4 SiC 4 composite sintered at 1650 °C were significantly higher than the hardness (13.2 GPa), fracture toughness (2.16 MPa·m 1/2 ), and thermal conductivity (7.8 W/(m·K)) of the monolithic Al 4 SiC 4 ceramics. The improved mechanical and thermal properties of the composites were attributed to the high density, fine grain size, as well as the optimized grain boundary structure of the SiC/Al 4 SiC 4 composites.
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COLLOID AND POLYMER SCIENCE
·
2020
·Vol. 298
·期 3
·285-291
·
IF 1.536
Wang Minying,Mo Baohang,Chen Birong,Jiang Linbin,Yang Hua
PAM/OSA/PVA hydrogel was prepared by simple copolymerization using acrylamide (PAM), oxidized sodium alginate (OSA), and poly (vinyl alcohol) as monomers. The hydrogel exhibited a quadruple-shape memory effect based on imine, coordination, and borate bonds. Self-healing properties of the quadruple-shape memory hydrogel were observed to evolve due to the imine and borate bonds. The hydrogel demonstrated tunable mechanical properties because of supramolecular interactions including OSA –Ca 2+ , PVA –borax, and OSA –PAM in different conditions. The new hydrogel is envisaged to increase the variety as well as broaden the design and manufacturing of shape memory hydrogels.
Dual multi-shape memory images of PAM/OSA/PVA hydrogel and its shape memory mechanism.
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Nutrition & Metabolism
·
2020
·Vol. 17
·期 1
·1-14
·
IF 3.211
Zeng Xin,Zhu Min,Liu Xiaohong,Chen Xuanmin,Yuan Yujia,Li Lan,Liu Jingping,Lu Yanrong,Cheng Jingqiu,Chen Younan
Background Pyroptosis is a novel programmed cell death. It is identified as caspase-1 dependent and characterized by plasma-membrane rupture and release of proinflammatory intracellular contents inculuding IL-1 beta and IL-18. Pyroptosis is distinct from other forms of cell death, especially apoptosis that is characterized by nuclear and cytoplasmic condensation and is elicited via activation of a caspase cascade. In pyroptosis, gasdermin D (GSDMD) acts as a major executor, while NLRP3 related inflammasome is closely linked to caspase-1 activation. Given that pyroptosis has played a critical role in the progression of non-alcoholic steatohepatitis (NASH), here, we investigated whether the regulation of pyroptosis activation is responsible for the protective role of monounsaturated oleic acids in the context of hepatocellular lipotoxicity.Methods Human hepatoma cell line HepG2 cells were exposed to palmitic acid (PA) with or without oleic acids (OA) or/and endoplasmic reticulum (ER) stress inhibitor tauroursodeoxycholic acid (TUDCA) for 24 h. Besides, the cells were treated with the chemical ER stressor tunicamycin (TM) with or without OA for 24 h as well. The expressions of pyroptosis and ER stress related genes or proteins were determined by real-time PCR, Western blot or immunofluorescence. The morphology of pyroptosis was detected by acridine orange and ethidium bromide (AO/EB) staining. The release of IL-1 beta and tumor necrosis factor alpha (TNF-α) was determined by ELISA. Sprague–Dawley (SD) rats were fed with high fat diet (HFD) for 16 w, then, HFD was half replaced by olive oil to observe the protective effects of olive oil. The blood chemistry were analyzed, and the liver histology and the expressions of related genes and proteins were determined in the liver tissues.Results We demonstrated that PA impaired the cell viability and disturbed the lipid metabolism of HepG2 cells (P < 0.01), but OA robustly rescued cells from cell death (P < 0.001). More importantly, we found that instead of cell apoptosis, PA induced significant pyroptosis, evidenced by remarkably increased mRNA and protein expressions of inflammasome marker NLRP3, Caspase-1 and IL-1beta, as well as cell membrane perforation driving protein GSDMD (P < 0.05). Furthermore, we demonstrated that the PA stimulated ER stress was causally related to pyroptosis. The enhanced expressions of ER stress markers CHOP and BIP were found subcellular co-located to pyroptosis markers NLRP3 and ASC. Additionally,TM was able to induce pyroptosis like PA did, and ER stress inhibitor TUDCA was able to inhibit both PA and TM induced ER stress as well as pyroptosis. Furthermore, we demonstrated that OA substantially alleviated either PA or TM induced ER stress and pyroptosis in HepG2 cells (P < 0.01). In vivo, only olive oil supplementation did not cause significant toxicity, while HFD for 32 w obviously induced liver steatosis and inflammation in SD rats (P < 0.05). Half replacement of HFD with olive oil (a mixed diet) has remarkably ameliorated liver abnormalities, and particularly inhibited the protein expressions of either ER stress and pyroptosis markers (P < 0.05).Conclusion Palmitic acid induced predominant pyroptosis in HepG2 cells, and ER stress may be responsible for the induction of pyroptosis and subsequent cell death. Monounsaturated oleic acids were able to ameliorate hepatocellular lipotoxicity both in vitro and in vivo, and OA mediated inhibition of ER stress and pyroptosis may be the underlying mechanisms.
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高影响因子
CURRENT MICROBIOLOGY
·
2020
·Vol. 77
·期 6
·1016-1023
·
IF 1.746
Yue Xue,Yan Bingyu,Wang Shuai,Gao Wen,Zhang Ruiyan,Dong Huijun
The glycopeptide A40926 biosynthesized by Nonomuraea gerenzanensis is a precursor of the second generation glycopeptide antibiotic dalbavancin. The skeleton of this glycopeptide consists of seven amino acids and is biosynthesized by the NRPS gene module. L-valine, a branched amino acid, is also a significant precursor for A40926 production. This study details the use of pH-responsive alginate–chitosan microspheres loaded with L-valine prepared by internal emulsification gelation. The effects of process and formulation variables on microsphere size, loading capacity, and encapsulation efficiency were investigated. Then, effects on A40926 production by the pH-responsive microspheres were evaluated in a 10-L fermenter. Results demonstrated that use of the pH-responsive microspheres could improve A40926 yield from 465 to 602 mg L −1 in a 10-L scale fermenter.
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KOREAN JOURNAL OF CHEMICAL ENGINEERING
·
2020
·Vol. 37
·期 2
·224-230
·
IF 2.69
Si Zhihao,Zhang Xin,Zuo Miao,Wang Tao,Sun Yong,Tang Xing,Zeng Xianhai,Lin Lu
2, 5-furandicarboxylic acid (FDCA) is a one of the most promising biomass-derived chemicals to substitute the non-renewable terephthalic acid as the monomer for producing polyethyleneterephthalate. At present, the oxidation of HMF is regarded as a prevalent way to prepare FDCA. Nevertheless, the isolation and storage of HMF is still a challenge. Herein, based on the higher stability of 5-formyloxymethylfurfural (FMF) than 5-hydroxymethylfurfural (HMF), we present an effective preparation route to prepare FDCA by substituting HMF with FMF as feedstock. A complete conversion of FMF and a 93.55% selectivity of FDCA were obtained in the mixed solvent of water and 1, 2-dioxane using Ru/C as catalyst and O 2 as oxidant. An improved process was developed for preparing FDCA using FMF as feedstock. The investigation of conversion pathway showed that FMF and HMF were simultaneously oxidized to 2, 5-diformylfuran (DFF) in a case of the existence of the reversible equilibrium between FMF and HMF. Then DFF was oxidized to 5-formyl-2-furancarboxylic acid (FFCA). Subsequently, FFCA was oxidized to FDCA. In this process, the oxidation of FFCA to FDCA was determined as the rate-determining step. Furthermore, appropriate alkalinity favored the selectivity of FDCA and the conversion of FMF.
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Scientific Reports
·
2020
·Vol. 10
·期 1
·1-10
·
IF 3.998
Yan Qinghua,Zhi Na,Yang Li,Xu Guangri,Feng Qigao,Zhang Qiqing,Sun Shujuan
A uric acid (UA) electrochemical biosensor was constructed using ferrocene (Fc) decorated cuprous oxide (Cu 2 O) enhanced electro-active characteristics and covalently immobilized with uricase (UOx) on glassy carbon electrode (GCE). The electrochemical characteristics of the fabricated electrode was analysed by cyclic voltammetry, electrochemical impedance spectroscopy and differential pulse voltammetry (DPV). DPV studies revealed rapid response of fabricated electrode UOx/Fc/Cu 2 O/GCE towards UA in a wide concentration range of 0.1–1,000 μM with a sensitivity of 1.900 μA mM −1 cm −2 and very low detection limit of 0.0596 μM. A very low magnitude Michaelis–Menten constant (Km) value was evaluated as 34.7351 μM which indicated the chemical attraction of the enzyme towards the UA was much higher. The developed biosensor was successfully applied to detect UA in human urine samples. Moreover, reproducibility and stability studies demonstrated the fabricated UOx/Fc/Cu 2 O/GCE biosensor had high reproducibility with a RSD of 2.8% and good reusability with a RSD of 3.2%. Specificity studies results showed the fabricated biosensor had strong anti-interference ability. The improved sensor performance was attributed to the synergistic electronic properties of Cu 2 O and Fc that provided enhances delectrocatalytic activity and electron transfer. The present biosensor can be extended for use in clinical settings.
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CATALYSIS LETTERS
·
2020
·Vol. 151
·期 1
·95-106
·
IF 2.482
Zhang Peng,Mao Xiangyang,Mi Rongli,Wang Lu,Yang Bolun
Abstract An effective, green method was proposed to prepare mesoporous SiO 2 encapsulated phosphotungstic acid (HPW) catalysts for alkylation desulfurization of 3-methylthiophene (3-MT). 3-aminopropyl triethoxysilane (APTES) was added to promote the formation of SiO 2 gel and immobilize HPW during preparation. Then, SiO 2 encapsulated HPW catalysts were characterized by XRD, N 2 physical adsorption, SEM, TEM, EDS, Ultraviolet–Visible spectrum, FTIR, NH 3 -TPD to study the physical and chemical properties. Characterization results show that the initial Keggin structure of HPW was remained during the preparation and there exist strong interaction between HPW and SiO 2 . Activity of catalysts is superior to that of reported SBA-15 encapsulated HPW catalysts, due to more effective encapsulation of HPW. The conversion of 3-MT could reach 99% with HPW content of 30.8% under reaction conditions (reaction temperature of 363 K, reaction time of 60 min and 1% catalyst dosage). Reducing the olefin content will not reduce the conversion of 3-MT but could effectively reduce the self-polymerization of olefin, which is also beneficial to reusability of catalysts. Graphic Abstract
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WATER AIR AND SOIL POLLUTION
·
2020
·Vol. 231
·期 5
·1-10
·
IF 1.9
Wang Ning,Zhang Feiyan,Mei Qiufeng,Wu Ronglan,Wang Wei
The harm of chromium pollution to the environment has caused a widespread concern; hexavalent chromium is a toxic, cancerogenic, and genetically mutagenic contaminant to the human body; by contrast, trivalent chromium is almost non-toxic to the human body; therefore, it is a feasible method to reduce hexavalent chromium to trivalent chromium. Photocatalysis is a new environmentally friendly and harmless technology, which can transform pollutants into non-toxic or less toxic products. In this study, we synthesized TiO 2 /rGO/CuO ternary nanocomposites to treat hexavalent chromium pollution under visible light. Under optimal conditions, the photoreduction efficiency of 100 ppm hexavalent chromium solution could reach 100% in 80 min. The photoreduction rate of hexavalent chromium is 29.4 times than that of pure TiO 2 . The photocatalytic property of CuO in TG2C8 nanocomposites is attributed to accelerate the separation of electrons and holes and the efficient electron transfer through the rGO framework. We believe that TiO 2 /rGO/CuO composites have great potential in wastewater treatment.
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