JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2023
·Vol. 34
·期 7
·1-14
·
IF 2.8
Guo Yan,Zhang Xinxu,Zhang Rui,Li Aiyuan,Zhang Jiawen,He Hui
In this work, Bi 2 O 3 and Bi 2 S 3 nanomaterials are modified with polyvinylpyrrolidone (PVP). The products are defined as Bi 2 O 3 @PVP and Bi 2 S 3 @PVP, respectively. SEM demonstrates that the addition of PVP helps to reduce the size of Bi 2 O 3 and Bi 2 S 3 nanomaterials. XRD exhibits that the structure of Bi 2 O 3 changed from α-Bi 2 O 3 to β-Bi 2 O 3 @PVP due to the addition of PVP, while the Bi 2 S 3 configuration remained unchanged. XPS demonstrates that excess PVP leads to a partial reduction of trivalent Bi 3+ to metallic Bi 0 . Their supercapacitive performances are tested and it is found that appropriate PVP can improve the capacitive performance and cyclic stability of both Bi 2 O 3 and Bi 2 S 3 . The specific capacitance of Bi 2 O 3 @1 g PVP is 1.4 times that of the pristine Bi 2 O 3 , and the specific capacitance of Bi 2 S 3 @1 g PVP is 1.8 times that of the pristine Bi 2 S 3 . Compared with 82.0% Bi 2 O 3 and 79.6% Bi 2 S 3 , the cyclic retention is 94.7% and 95.2% for Bi 2 O 3 @1 g PVP and Bi 2 S 3 @1 g PVP after 10,000 cycles. The reason for enhancement is that PVP can support Bi 2 O 3 and Bi 2 S 3 materials, not only to support their structural stability but also to reduce their size and facilitate electron transfer and ion diffusion.
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高影响因子
MACROMOLECULAR RESEARCH
·
2023
·Vol. 31
·期 3
·181-191
·
IF 2.4
Li Jiyu,Zhu Li,Wu Shuai,Wang Guixue,Chen Yidan,Wu Wei
Chemotherapy is the main strategy for inhibiting the tumor growth. However, during the therapy, the side effect of anti-cancer drug will injure normal cells. For reducing the toxic of the free drug, stimuli responsive nanoparticles (NPs) have been prepared base on the pathological acidic environment around tumor for safe and efficient anti-tumor applications. In this study, we fabricated the phenylboronic acid (PBA) modified monomethoxy polyethylene glycol (MEPG) for encapsulating doxorubicin (DOX NPs). In the drug delivery system (DDS), the pH-responsive boric ester could be stable during drug delivery, and enhance DOX rapidly release in tumor lesion under the acidic stimuli. In vitro studies further demonstrated that DOX NPs could efficiently endocytose by tumor cells, and exhibit the similar anti-tumor activity as the free DOX resulting from the pH-responsive drug release profiles under tumor acidic stimuli. In summary, DOX NPs could be a feasible candidate to improve the safe and efficient DOX delivery for improving the potential anti-tumor applications. Graphical abstract
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RARE METALS
·
2023
·Vol. 42
·期 6
·1969-1982
·
IF 8.8
Liao Jia-Lin,Zhang Shuai,Bai Tian-Sheng,Ji Feng-Jun,Li De-Ping,Cheng Jun,Zhang Hong-Qiang,Lu Jing-Yu,Gao Quan,Ci Li-Jie
Lithium metal batteries (LMBs) with a high theoretical capacity are seen as a type of the most potential energy storage system. Unfortunately, the growth of lithium dendrite, the irreversible side reactions, and the infinite volume alteration still curb the practical utilization of lithium metal anodes, resulting in low Coulombic efficiency (CE) and safety problems, etc. Herein, we synthesize a lithiophilic 3D copper foam host with uniformly distributed nano-flower-like ZnO particles (CuF/ZnO) and obtain the composite lithium metal anode containing the Li 2 O, LiZn alloy, and pure Li by the infusion of molten Li (CuF/Li 2 O-LiZn@Li). Benefitting from the advantages of the 3D structure of copper foam and the lithiophilicity of ZnO sites, the composite lithium metal anode can restrain the volume alternation and regulate the uniform deposition of lithium. The symmetrical cells of the composite lithium metal anode have a 1600 h long cycle life with a low polarization voltage of 15 mV, and the Coulombic efficiency can maintain about 97.8% at 1.0 mA·cm −2 , 1.0 mAh·cm −2 . Graphical abstract
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2023
·Vol. 30
·期 19
·55498-55512
·
IF 5.8
Chen Jing,Shan Mengde,Zhu Haojia,Zhang Shichuan,Li Jingmei,Li Leijiao
BiSnSbO 6 -ZnO composite photocatalytic material with type II heterojunction structure was synthesized by a simple solid-phase sintering method, it was characterized by XRD, UV–vis, and PT methods. The photocatalytic antibacterial experiments were carried out under LED light irradiation. The experimental results showed that the photocatalytic antibacterial properties of BiSnSbO 6 -ZnO composites against bacteria and fungi were significantly stronger than those of single BiSnSbO 6 and ZnO. Under light conditions, the antibacterial efficiencies of 500 mg/L BiSnSbO 6 -ZnO composites against E. coli , S. aureus , and P. aeruginosa reached 99.63%, 100%, and 100% for 6 h, 4 h, and 4 h, respectively. The best antibacterial concentration of BiSnSbO 6 -ZnO composite against the eukaryotic microorganism Candida albicans was 250 mg/L, and the antibacterial efficiency reached the highest 63.8% at 6 h. Antibacterial experiments were carried out on domestic livestock and poultry wastewater, which showed that the BiSnSbO 6 -ZnO composite photocatalytic material has broad-spectrum antibacterial activity against bacteria, and the antibacterial effect has species differences. Through the MTT experiment, it is proved that the prepared BiSnSbO 6 -ZnO composite photocatalytic material has no toxicity at the experimental concentration. According to the free radical scavenging experiment and SEM observation of the morphological changes of the bacteria after light treatment, the prepared BiSnSbO6-ZnO composite photocatalytic material can generate active species OH, h + , and e − through light irradiation to achieve the purpose of sterilization, where e − play a major role, indicating that the BiSnSbO 6 -ZnO composite photocatalytic material has broad application prospects in the actual antibacterial field.
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Cell Death & Disease
·
2023
·Vol. 14
·期 2
·1-13
·
IF 9
Liu Nian,Zhang Jianglin,Yan Mingjie,Chen Lihui,Wu Jie,Tao Qian,Yan Bei,Chen Xiang,Peng Cong
Patients with advanced melanoma have shown an improved outlook after anti-PD1 therapy, but the low response rate restricts clinical benefit; therefore, enhancing anti-PD1 therapeutic efficacy remains a major challenge. Here, our findings showed a significantly increased abundance of α-KG in healthy controls, anti-PD1-sensitive melanoma-bearing mice, and anti-PD1-sensitive melanoma patients; moreover, supplementation with α-KG enhanced the efficacy of anti-PD1 immunotherapy and increased PD-L1 expression in melanoma tumors via STAT1/3. We also found that supplementation with α-KG significantly increased the activity of the methylcytosine dioxygenases TET2/3, which led to an increased 5-hydroxymethylcytosine (5-hmC) level in the PD-L1 promoter. As a consequence, STAT1/3 binding to the PD-L1 promoter was stabilized to upregulate PD-L1 expression. Importantly, single-cell sequencing of preclinical samples and analysis of clinical data revealed that TET2/3-STAT1/3-CD274 signaling was associated with sensitivity to anti-PD1 treatment in melanoma. Taken together, our results provide novel insight into α-KG’s function in anti-PD1 treatment of melanoma and suggest supplementation with α-KG as a novel promising strategy to improve the efficacy of anti-PD1 therapy.
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高影响因子
FIBERS AND POLYMERS
·
2023
·Vol. 24
·期 2
·771-778
·
IF 2.5
Li Mengmeng,Xu Qiuyu,Jiang Wei,Farooq Amjad,Qi Yirui,Liu Lifang
Herein, Fe 3 O 4 nanoparticles and graphene oxide (GO) are compounded first, followed by the addition of cellulose nanofiber (CNF) and l -ascorbic acid, to obtain Fe 3 O 4 @reduced graphene oxide (rGO)/CNF foams via the freeze-drying method. The electrical conductivity and magnetism of as-prepared foams were improved due to the presence of rGO and Fe 3 O 4 , which is suitable for electromagnetic interference (EMI) shielding material. The results exhibit that Fe 3 O 4 @rGO/CNF foams all possess a porous structure, and the optimized foam shows an EMI shielding effectiveness value of ~ 23 dB in the X-band. The good EMI shielding performance of the Fe 3 O 4 @rGO/CNF foam originates from the synergy of its composition and structure. This work could provide a reference for the design and fabrication of novel EMI shielding materials.
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高影响因子
MACROMOLECULAR RESEARCH
·
2023
·Vol. 31
·期 3
·233-243
·
IF 2.4
Liu Peng,Bai Xiaoyu,Gao Xingtong,Liu Kai,Li Aixiang,Lyu Zijian,Li Qiuhong
In this paper, lutein block polyethylene glycol (lutein-b-PEG) copolymers were synthesized by hydrophilic modification of lutein with carboxylated polyethylene glycol (CT-PEG). The unreacted lutein was loaded into micelles formed by self-assembly of block copolymers to prepare composite nanoparticles. The results of FT-IR, 1 H NMR, gel permeation chromatography (GPC), UV–vis and critical micellar concentration (CMC) showed that the double terminal carboxyl group ratio of CT-PEG reached 50.31%, and lutein-b-PEG was successfully synthesized without destroying the structure of lutein. Compared with lutein, the retention rate of lutein composite nanoparticles increased from 4.32 to 81.3% after 30 days of storage in the dark. In addition, the saturation solubility and bioaccessibility of lutein nanoparticles were increased 35 times and 5.2 times, respectively, due to micellar formation and improved water solubility. These findings indicated that the lutein composite nanoparticles modified with PEG significantly improved the chemical stability, water solubility, and bioaccessibility of lutein.
Graphical abstract
Preparation and properties of lutein block polyethylene glycol copolymer loading with lutein nanoparticles
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高影响因子
ANALYTICAL SCIENCES
·
2023
·Vol. 39
·期 6
·935-943
·
IF 1.6
Wang Jingyu,Cui Yunyi,Lin Ying,He Yi
Abstract A long-standing challenge in colorimetric detection of triacetone triperoxide (TATP) explosive is low sensitivity. We herein developed an iodine-mediated photoinduced auto-inductive tandem chromogenic system to achieve exponential signal amplification. The strategy employs the KI-TATP reaction and photo-induced autocatalytical oxidation of o-phenylenediamine (OPD) that work in tandem. The resulting I 3 − from the KI-TATP reaction oxidizes OPD to yellow 2,3-diaminophenazine (DAP) that is further excited by blue light illumination to produce reactive oxygen species (ROS). The obtained ROS, in turn, promotes the oxidation of OPD to gain more DAP, causing the auto-inductive chromogenic reaction processes. This tandem chromogenic system is applied for visual colorimetric detection of TATP, allowing the selective and sensitive detection of TATP down to 42.8 μM. Moreover, analyses of TATP in real samples are performed, and the satisfactory recovery results are achieved. Furthermore, a field detection kit is also developed. Graphical abstract
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JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2023
·Vol. 332
·期 6
·1953-1960
·
IF 1.6
Luo Qingyun,Wang Chongshi,Zhu Wei,Yu Hongchao,Wang Chunyan,Chen Chuanhong
Due to its high adsorption capacity and adsorption efficiency, polymer gel shows excellent performances in the treatment of wastewater containing thorium. In this work, glutaraldehyde cross-linked N -(4-Aminobenzoyl)-ʟ-glutamic acid modified chitosan (CCS-AGA) was used to adsorb Th(IV) ions from aqueous solutions for the first time. FT-IR and SEM results revealed the chemical structure and surface morphology of this material. The influence of solution pH, contact time and initial concentration of Th ions on the adsorption of Th(IV) by CCS-AGA was investigated. The experimental data suggest that the adsorption behavior of CCS-AGA could be accurately predicted by the Langmuir model. The maximum theoretical adsorption capacity of CCS-AGA for Th(IV) was 162 mg/g. Moreover, this material exhibited excellent reusability and adsorption selectivity for Th(IV).
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高影响因子
NEUROCHEMICAL RESEARCH
·
2023
·
IF 4.4
Zhang Shuai-nan,Li Hong-mei,Liu Qi,Li Xu-zhao,Yang Wu-de,Zhou Ying
Epilepsy is a chronic brain disease and often occurs suddenly for no reason. Eucommiae folium (EF), an edible herb, can be used in the treatment of various kinds of brain diseases in clinic. From the perspective of safety and efficacy, EF is especially suitable for the treatment of chronic brain diseases. With the help of biolabels, this study was aimed to explore the value and feasibility of EF in the treatment of epilepsy. Proteomics and metabolomics were used to explore the biolabels of EF intervention in brain tissues. Bioinformatics was then applied to topologically analyze its neuroprotective effects and mechanisms and material basis based on biolabels, which were validated in an animal model. The biolabel-led research revealed that EF may exert the therapeutic potential to treat brain diseases through the interaction between multiple compounds and multiple targets, among which its therapeutic potential for epilepsy is particularly prominent. In the pentylenetetrazole-induction model, EF and four active compounds (oleamide, catechol, chlorogenic acid, and kaempferol) protected epileptic hippocampal neurons (Nissl and FJB staining) against mitochondrial dysfunction (MYH6, MYL3, and MYBPC3, etc.) and calcium overload (TNNI3, TNNC1, and TNNT2, etc.) through the hypertrophic cardiomyopathy pathway. This study provides new evidence and insights for the neuroprotective effects of EF, in which four active compounds may be potential drug candidates for the treatment of epilepsy.
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高影响因子
Nano Research
·
2023
·
IF 9.9
Shen Chen,Li Huiyong,Sun Shuai,Zhang Hui,Yan Lanqin,Zhang Zhong
Although ultrablack surfaces are urgently needed in wide applications owing to their extremely low reflectance over a broadband wavelength, obtaining simultaneously the ultrablackness and mechanical robustness by simple process technique is still a great challenge. Herein, by decoupling different light extinction effects to different layers of coating, we design an ultrablack coating that is all-sprayable in whole process. This coating presents low reflectance over visible-mid-infrared (VIS-MIR) wavelength (av. R ≈ 1% in VIS), low multi-angle scattering (bidirectional reflection distribution function (BRDF) = 10 −2 −10 −3 sr −1 ), together with good substrate adhesion grade and self-cleaning ability, which are superior to most reported sprayable ultrablack surfaces. The light extinction effects of each layer are discussed. This method is also applicable in other material systems.
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Gut Pathogens
·
2023
·Vol. 15
·期 1
·1-14
·
IF 4.2
Wang Shanshan,Wen Qiuyu,Qin Yan,Xia Quan,Shen Chenlin,Song Shuai
Background The pseudo germ-free (PGF) model has been widely used to research the role of intestinal microbiota in drug metabolism and efficacy, while the modelling methods and the utilization of the PGF model are still not standardized and unified. A comprehensive and systematic research of the PGF model on the composition and function of the intestinal microbiota, changes in host cytochrome P450 (CYP450) enzymes expression and intestinal mucosal permeability in four different modelling cycles of the PGF groups are provided in this paper.Results 16S rRNA gene amplicon sequencing was employed to compare and analyze the alpha and beta diversity, taxonomic composition, taxonomic indicators and predicted function of gut microbiota in the control and PGF groups. Bacterial richness and diversity decreased significantly in the PGF group beginning after the first week of establishment of the PGF model with antibiotic exposure. The PGF group exposed to antibiotics for 4-week-modelling possessed the fewest indicator genera. Moreover, increased intestinal mucosal permeability occurred in the second week of PGF model establishment, indicating that one week of antibiotic exposure is an appropriate time to establish the PGF model. The results of immunoblots revealed that CYP1A2, CYP2C19 and CYP2E1 expression was significantly upregulated in the PGF group compared with the control group, implying that the metabolic clearance of related drugs would change accordingly. The abundance of functional pathways predicted in the gut microbiota changed dramatically between the control and PGF groups.Conclusion sThis study provides information concerning the microbial and CYP450 enzyme expression profiles as a reference for evaluating drug metabolism differences co-affected by gut microbiota and host CYP450 enzymes in the PGF model.
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