JOURNAL OF POWER SOURCES
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2024
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IF 8.1
Wenyi Wang,Han Ren,Junhan Guo,Sidi Wang,Jia Wang,Yuanyuan Wang,Wencong Sun,Long Tang,Xueqin Wang
Fuel cells require efficient and durable electrocatalysts to improve oxygen reduction reactions (ORR) to mitigate the current energy crisis. However, unsatisfactory catalytic activity and stability caused by slow kinetics and mass transport characteristics restrict the further development of fuel cells. Here, a preparation strategy is proposed for manufacturing iron single-atom catalyst modified by sulfur doping dispersed over nitrogen-doped carbon nanotubes (NCNTs@Fe-NSC). Both experimental theoretical results prove that legitimately engineered substitution doping of coordination structure can effectively regulate charge balance of centers to optimize the adsorption and desorption energy of oxygen-containing intermediates and improve the activation energy barrier of elementary reaction. The NCNTs@Fe-NSC achieves astonishing ORR capacity and satisfactory electrocatalytic stability with a loss of activity about 2.4 % after 60 h, including poison resistance, in neutral electrolyte. This study provides a perspicacious thought for rational design of single atom catalysts using element doping engineering to achieve high efficiency electrocatalysis.
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FITOTERAPIA
·
2024
·
IF 2.5
Hongliu Xie,Fang Lin,Fei Shi,Elaine Johnstone,Yaqi Wang,Yang An,Jun Su,Jiayin Liu,Qinghai Dong,Jihua Liu
As one of the metabolites of ginseng, 20( S )-protopanaxadiol (PPD) is a compound with dammarane-type tetracyclic triterpene, which performs a wide range of anticancer activities. In this study, PPD was used as a lead. A series of compounds were synthesized respectively with 11 amino acids through esterification and were evaluated for their cytotoxicity against several cancer cell lines. One of the synthetic products (PL) exhibited potent inhibitory effect on Huh-7 cells relative to that of PPD in vitro. Subsequently, the Annexin V-FITC /PI staining assay was used to verify that PL induced apoptosis of Huh-7 cells in a dose-dependent manner. A UPLC-Q/TOF-MS analysis method was established and validated for assessing pharmacokinetic properties after the administration of PPD and PL in rats. The results showed that compared with PPD, T 1/2 of PL in rats was prolonged, and the peak time was delayed, resulting in broader tissue distribution of the compound in the body. In addition, the targets of PL against several cancers were predicted and analyzed via network pharmacology. Molecular docking simulations demonstrated that PL interacted with the active sites of the above targets. In conclusion, this study provided a theoretical basis for the development and clinical application of anti-tumor activity of PPD.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2025
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IF 3.9
Yan Zhang,HuiYi Pan,Mengru Wang,Xiying Li,Guifeng Lu
Carbon-based composites, especially for heteroatom incorporation including P, S, N, and B, show excellent performance in the ORR and are promising alternatives in place of Pt/C catalysts. However, complex procedures are necessary for the synthesis of the precursors acting as suitable carbon-based electrocatalysts. Herein, a simple method, based on the Schiff-base reaction, offering the privileges of devising the N-containing precursors, is developed to synthesize an efficient ORR catalyst. In this study, a Schiff-base polymer with nanoflower morphology (CNF-P) is synthesized via the reaction of 3,5-diaminobenzoic acid and terephthalaldehyde at room temperature. Subsequently, the N/S-codoped carbonaceous nanoflower electrocatalyst derived from its polymer counterpart (N/S-CNF900) is fabricated through high-temperature pyrolysis of CNF-P with thiourea. Benefitting from the dopants of N and S atoms, the N/S-CNF900 sample demonstrates exceptional ORR activity, offering an E1/2 of 0.87 V, Eonset of 1.02 V, and jm of 6.05 mA cm–2, as well as excellent durability and methanol resistance. When utilized as the air electrode in ZABs, N/S-CNF900 demonstrates superior power output of 178 mW cm–2 coupled with exceptional charge–discharge durability spanning 282 h. The superior electrochemical performance stems from the abundant active sites created by heteroatomic N/S doping with a very high specific surface area and the multilevel porous architecture, thereby ensuring effective exposure of active sites. These findings suggest that the catalyst synthesized through the Schiff-base reaction holds promising potential applications in alkaline zinc–air batteries (ZABs).
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ACS Applied Nano Materials
·
2025
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IF 5.5
Xiaowei Ma,Lin Tan
Metal–organic frameworks (MOFs)-derived compounds exhibit tremendous potential for applications in the field of microwave absorption, attributed to their unique structural characteristics, high specific surface area, and tunable magnetic and dielectric properties. However, their practical application in the microwave absorption field is limited by poor impedance matching. To address this issue, we successfully synthesized a composite microwave-absorbing material, labeled as Fe/Fe2O3/C/N,SGPE, by introducing heteroatom (N and S) codoped graphene (labeled as N,S-GPE) into an Fe/Fe2O3/C MOF derivative and employing a solvothermal method followed by subsequent pyrolysis. The introduction of N and S codoped graphene introduces defects and disordered structures, thereby enhancing interface and dipolar polarization processes, which in turn improve the dielectric properties and optimize impedance matching. The experimental results demonstrate that when the addition amount of N,S-GPE is 0.15 g, the material exhibits a maximum reflection loss of -62.8 dB at 7.6 GHz with a thickness of 3.09 mm, capable of absorbing over 99.9999% of microwaves. Consequently, this composite stands out as a promising candidate for high-efficiency microwave absorbers.
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 9
·1-14
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IF 5.3
Cao Xiaodong,Zhang Chenlu,Gao Yu,Yu Weina,Liu Chao,He Shudong,Sun Hanju,Ye Yongkang
Foodborne pathogens are a leading cause of food safety incidents. Here, we developed a highly sensitive dual-channel biosensor for the parallel electrochemical detection of Salmonella typhimurium ( S. typhimurium ) and Escherichia coli ( E. coli ) O157:H7 using bimetallic metal–organic framework (BMOF)-based signal nanotags. The BMOF-based nanotags were synthesized by functionalizing gold nanoparticle-doped CuZr-MOF with signal DNA sequences sDNA1 (forming sDNA1-AuNPs@CuZr-MOF nanotag) and PbZr-MOF with signal DNA sequence sDNA2 (forming sDNA2-AuNPs@PbZr-MOF nanotag). The biosensing platform was constructed using two glassy carbon electrodes (GCEs). Each GCE was sequentially modified, first with electrodeposited gold nanoparticles (depAu) and then with the corresponding capture DNA sequences (cDNA1 for channel 1 or cDNA2 for channel 2). Target detection was achieved on the sensing interface via sandwich hybridization: in channel 1, the invA gene of S. typhimurium (tDNA1) was recognized by both cDNA1 on the sDNA1-AuNPs@CuZr-MOF nanotag; similarly, in channel 2, the eaeA gene of E. coli O157:H7 (tDNA2) was recognized by both cDNA2 and sDNA2 on the sDNA2-AuNPs@PbZr-MOF nanotag. Leveraging the high stability and ease of surface modification of UiO-66 (Zr-MOF), along with the enhanced electrochemical oxidation signals from the introduced secondary metal ions (Cu 2+ and Pb 2+ ) in Zr-MOF framework, the biosensor achieved parallel detection with wide linear ranges (3.5 to 3.5 × 10 5 CFU mL −1 for S. typhimurium , and 2.2 to 2.2 × 10 5 CFU mL −1 for E. coli O157:H7) and low detection limit (LODs of 0.54 CFU mL −1 and 0.80 CFU mL −1 , respectively). Furthermore, the fabricated biosensor demonstrated excellent reproducibility, selectivity, and stability, highlighting great potential for practical use in monitoring foodborne pathogens. Graphical
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
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IF 9.7
Yue Sun,Chenrui Zhao,Jin Xu,Yazi Liu,Huan He,Feihu Mu,Wei Zhao,Dan Sun,Shaogui Yang,Cheng Sun
The construction of built-in electric field (BIEF) in heterojunction is an effective strategy to enhance solar-driven hydrogen (H 2 ) production by minimizing charge carrier recombination and improving transport kinetics. Herein, p-type ternary sulfide CuGaS 2 (CGS) and n-type g-C 3 N 4 nanosheets (CN) are integrated to construct a p-n heterojunction through a simple co-precipitation method for photocatalytic hydrogen evolution reaction (HER). In situ X-ray photoelectron spectroscopy (in situ XPS), in situ electron paramagnetic resonance (EPR) and density functional theory (DFT) calculations revealed that differences in Fermi levels and carrier concentrations between CGS and CN induce charge migration following an S-scheme mechanism, which aligned well with the intrinsic p-n junction field. The escalated BIEF effect enhances interfacial band bending, drives efficient charge separation, and promotes directional charge transfer. As a result, the optimized 20CN/CGS photocatalyst achieves a high H 2 evolution rate of 563 ± 5 μmol g cat −1 , approximately 3.3 times that of CGS. Additionally, the 20CN/CGS exhibits photothermal properties with further boosted HER rate of 732 ± 6 μmol g cat −1 at 35 °C, achieving a photothermal conversion efficiency (PCE) of 11 ± 2 %. This indicates its potential for exploitation of thermal heat from solar spectrum. This work provides a promising strategy for designing high-performance p-n heterojunction governed by S-scheme charge transfer to boost solar energy conversion.
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POLYMER
·
2025
·
IF 4.5
Jinghang Zhu,Jiahao Shen,Haitong Zhao,Honghong Luo,Yiqun Fang,Weihong Wang,Yongming Song,Qingwen Wang
s With growing global resource constraints and environmental concerns, sustainable and eco-friendly characteristics have made bio-based materials the focus of considerable attention. In this work, a novel bio-based composite intumescent flame retardant (SVDP), incorporating P, N, and S as flame-retardant elements, was prepared through Schiff base condensation, addition reaction, and electrostatic ionic interaction, employing phytic acid, vanillin, sulfonamide, and 9,10-dihydro-9-oxa-10-phospha-phenanthrene-10-oxide as precursors. SVDP was introduced into polypropylene-based wood-plastic composites (WFPP) to enhance flame retardancy and smoke suppression performance. Relative to the neat WFPP, the incorporation of 20 wt% SVDP increased the limiting oxygen index (LOI) to 27.2%, while the peak heat release rate (PHRR) decreased by 23.3% and the total heat release (THR) declined by 25.8%. Even at low loadings, SVDP demonstrated notable smoke suppression effects. The flame-retardant mechanism of the SVDP/WFPP system was comprehensively investigated using TG-FTIR, Raman spectroscopy, SEM, and other characterization techniques. By employing a multifunctional bio-based composite flame retardant, this work provides an eco-friendly and efficient strategy to strengthen the fire-retardant performance of wood-plastic composites.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Jiepeng Zhao,Zijian Li,Yu Zuo,Sai Huang,Zhaomin Tong,Yifei Ma,Liantuan Xiao,Suotang Jia,Xuyuan Chen,Mei Wang
NH 2 -MIL-125(Ti) (NM) is a prototypical metal–organic framework (MOF) photocatalyst with visible-light responsiveness. However, its practical application in CO 2 reduction is significantly limited by fast charge carrier recombination and poor product selectivity. Constructing heterojunctions with appropriately matched semiconductors offers an effective strategy to overcome these limitations, where coupling material selection and precise interfacial engineering are key. ZnO, a stable n-type wide-bandgap semiconductor, not only possesses excellent electron mobility but also exhibits suitable conduction band alignment with NM, enabling favorable interfacial charge transfer. Moreover, ZnO can form an interfacial Ti–O–Zn bonding bridge with NM, facilitating directional electron transport and suppressing charge recombination. In this work, we employed atomic layer deposition (ALD) to construct uniform ZnO shells on NM with sub-nanometer precision, thereby finely tuning the ZnO loading and interface structure. A series of ZnO@NH 2 -MIL-125 (ZnO@NM) composites are obtained by controlling the ZnO loading, with the optimal sample showing the highest activity, yielding 13.30 μmol h −1 g −1 of CO and 5.47 μmol h −1 g −1 of CH 4 . Notably, CH 4 selectivity is significantly improved from 16 % to 29 %, and further increases to 31 % under gas-solid conditions. In situ Fourier Transform Infrared (FTIR) spectroscopy and Density Functional Theory (DFT) calculations reveal that ZnO not only promotes directional interfacial electron transfer but also facilitates the hydrogenation of *CO to *CHO, thus enhancing CH 4 selectivity. This study demonstrates an ALD-enabled interface engineering strategy to construct MOF-semiconductor heterojunctions, offering mechanistic insights and design principles for advancing efficient and selective photocatalytic systems for carbon dioxide reduction.
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Nano Energy
·
2025
·
IF 17.1
Ying Wang,Ruolan Zhao,Yachao Xu,Bojing Sun,Zhong Zhou,Peng Yu,Yue Qu,Youxing Liu
Solar driven the conversion of plastic waste, one of emerging environmental pollution sources, into clear energy and high value-added products, is of great significance for human health and sustainable economic development globally, however, still suffer from low reaction kinetics and unsatisfactory selectivity. Herein, we proposed a new strategy of zinc indium sulfide (ZIS) nanosheets anchoring Pt cluster (ZIS-Pt-Clu) for enhancing local surface plasmon resonance (LSPR), by accurately synthesizing S-Pt coordination bond for constructing electron transport channel, for the purpose of promoting the reaction kinetics and selectivity of plastic waste into hydrogen and high value-added products. Experiment shows that the as-made ZIS-Pt-Clu photocatalyst exhibits a high hydrogen production rate of 11.7 mmol h −1 g −1 , together with 97.5 % of selectivity of polylactic acid (PLA) to pyruvic acid (PA), which is the best compare with ZIS/Pt-Clu without hot electron transport channel and reported active materials. In addition, the S-Pt coordination bond also triggers strong interface crystal field between Pt cluster and ZIS to promote the separation and transport of photogenerated carriers, which accelerates the photocatalytic conversion of PLA into H 2 and PA. Overall, this work reportes a new strategy of LSPR enhanced photocatalytic performance, opening the door for the fundamental research of designing high performance photocatalyst for the degradation of plastic waste to the production of new energy and high value-added products.
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ACS Applied Polymer Materials
·
2025
·
IF 4.7
Qiaoqiao Liu,Zihao Luan,Xin Shi,Yinxiao Zhu,Zheliang Nie,Bingcheng Ge,Shuyan Gao
Leveraging the superior conductivity and stretchability of hydrogels to promote their application in flexible electronic devices represents an effective approach to advancing the field of flexible sensors. Starch-based hydrogels, which possess advantages such as biodegradability, biocompatibility, and nontoxicity, are highly desirable for flexible sensors. However, the numerous hydrogen bonds within starch chains and the poor dispersibility of conductive materials in the hydrogel restrict the balance between stretchability and conductivity, posing a significant challenge in the development of flexible sensors. Herein, a multinetwork structure is designed to prepare a potato starch (S–S)/poly(vinyl alcohol)/N-isopropylacrylamide/carboxymethyl cellulose-Ag nanowires1.5 (PTS/PVA/NIPAM/CMC-Ag1.5) hydrogel material featuring favorable stretchability (1343% elongation) and conductivity (1.6 S/m). Functionally, the multinetwork and reversible dynamic bonds enable the PPNC-Ag1.5 hydrogel to achieve high self-healing efficiency (up to 90%) and recyclability. Antimicrobial tests show that the PPNC-Ag1.5 hydrogel exhibits excellent inactivation of Escherichia coli and Staphylococcus aureus, with sterilization rates of 99.44% and 91.91%, respectively. Furthermore, the PPNC-Ag1.5 hydrogel is used to develop strain/temperature sensors that exhibit high sensitivity to strain (gauge factor, F = 1.3) and temperature (temperature coefficient of resistance, TCR = 2.5%/°C). This strategy overcomes the trade-off between strain and electrical properties of starch-based hydrogels, thereby demonstrating significant potential for applications in the fields of fever monitors and motion monitors.
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ACTA PHYSICO-CHIMICA SINICA
·
2025
·
IF 13.5
Shiyi Chen,Jialong Fu,Jianping Qiu,Guoju Chang,Shiyou Hao
The coronavirus disease 2019 (COVID-19) pandemic has increased the necessity of medical masks, and to date, many waste masks have been discarded without being reprocessed, causing environmental harm. PET, a commonly used plastic product, presents certain hurdles to its natural degradation. In this work, waste medical masks were converted into carbon quantum dots (MCQDs) with blue fluorescence emissions using a simple solvothermal process and then doped into BiOBr/g-C 3 N 4 composite material to construct S-scheme heterojunctions for PET degradation. Density functional theory (DFT) calculations revealed that an interfacial electric field (IEF) was formed between g-C 3 N 4 and BiOBr. The findings demonstrate that the MCQDs, as a cocatalyst for electron transmission and storage, encourage S-scheme heterojunctions to further separate photogenerated electrons and holes. Levofloxacin (LEV) was used as a molecular probe to visually compare the catalytic activities of various catalysts. These catalysts with different photocatalytic activity were then used to degrade PET. The findings demonstrate that the degradation efficiency of PET over the BiOBr/g-C 3 N 4 /3MCQDs in seawater is 39.88 ± 1.04% (weight loss), which is 1.37 times higher than that of BiOBr/g-C 3 N 4 , and also better than those reported in most of the literature. Free radical capture tests, electrostatic field orbital trap high-resolution gas chromatography-mass spectrometry (HRGC-MS), and ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) experiments uncovered and briefly revealed the key products in the photocatalytic degradation of PET, as well as the relevant mechanism of photocatalytic degradation of PET. The degradation products are expected to become precursors for the further production of polymers and medicines, etc . This study offers fresh perspectives for the creation of innovative photocatalysts for the ecologically benign breakdown of PET, which helps to further lessen environmental damage caused by microplastics (MPs) and enhance resource sustainability.
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CURRENT NEUROVASCULAR RESEARCH
·
2021
·Vol. 18
·期 1
·102-112
·
IF 1.99
Chu Miao,Liu Huimiao,Xiong Zhaohui,Ju Chaojuan,Zhao Lina,Li Kangning,Tian Shiqi,Gu Ping
Background: Parkinson’s disease (PD) is a neurodegenerative disorder caused by the progressive loss of dopaminergic neurons. Canopy fibroblast growth factor signaling regulator 2 (CNPY2) is down-regulated in this disease, but its functions are unknown. Objective: This study
investigates the effects and regulation of CNPY2 in the apoptosis of neurons in PD. Methods: We established a PD model in vivo by a five consecutive days-injection of 1-methyl-4- phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) to mice. In vitro, the human SH-SY5Y neuroblastoma cells, after
differentiation, were treated with 1-Methyl-4-phenylpyridinium iodide (MPP+) for modeling. The cells were transfected with a recombinant vector overexpressing CNPY2 followed by MPP+ treatment. Expression of CNPY2 and proteins related to apoptosis was detected by real-time PCR, western blot,
or immunofluorescence staining. The ROS level and mitochondrial membrane potential were determined by flow cytometry. Cell viability and apoptosis were measured by MTT assay and TUNEL staining. Results: CNPY2 level was down-regulated both in the brain and retina of PD mice and also inhibited
in neurons by MPP+ in vitro. Overexpression of CNPY2 repressed the level of Bax and cleaved caspase-3, enhanced Bcl-2 level, and promoted neurite length under MPP+ treatment. CNPY2 overexpression reduced the accumulation of ROS and mitochondria dysfunction in neurons. The AKT/ GSK3β signaling
pathway was activated by overexpressed CNPY2 to inhibit MPP+-induced neuronal apoptosis, which was confirmed using an AKT inhibitor MK-2206 2HCl. Conclusion: CNPY2 alleviates oxidative stress, mitochondria dysfunction, and apoptosis of neurons induced by MPP+ by activating the AKT/ GSK3β
signaling pathway.
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