INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Mingshan Chen,Zhiyu Hu,Haoyuan Zheng,Jiesheng Wang,Xiaowen Xu
While hydrogels have potential for food packaging, limited research on hydrogels with excellent mechanical performance and antibacterial activity for preserving chicken breasts. Herein, we created antibacterial hydrogels by embedding methyl-β-cyclodextrin/thyme oil inclusion complexes (MCD/TO-ICs) into a polyvinyl alcohol matrix containing dendrobium polysaccharides and guar gum in varying ratios using freeze-thaw cycling method. The resulting hydrogels exhibited a more compact structure than those without MCD/TO-ICs, enhancing thermal stability and increasing glass transition temperature due to additional intermolecular interactions between polymer chains that inhibited chain movement. XRD analysis showed no significant changes in crystalline phase, enabling formation of a 3D network through abundant hydrogen bonding. Moreover, the hydrogel demonstrated exceptional durability, with a toughness of 350 ± 25 kJ/m 3 and adequate tearing resistance of 340 ± 30 J/m 2 , capable of lifting 3 kg weight, 1200 times greater than the hydrogel itself. Additionally, the hydrogels displayed excellent antimicrobial activity and antioxidant properties. Importantly, the hydrogels effectively maintained TVB-N levels and microbial counts within acceptable ranges, preserving sensory properties and extending the shelf life of chilled chicken breasts by four days. This study highlights the potential of MCD/TO-IC-incorporated polysaccharide hydrogels as safe and effective active packaging solutions for preserving chilled chicken in food industry.
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TALANTA
·
2025
·
IF 6.1
Hao Shen,Mengdi Hao,Shaoning Yu
β-Amylase (BMY) is a linchpin in food production and the pharmaceutical industry because the enzyme efficiently controls the ratio of diverse saccharides in fermentation and the manufacture of high-quality maltose. However, existing BMY detection tactics suffer from inadequate selectivity/sensitivity and cumbersome operation and do not meet the needs of precise quantification. Consequently, there is an urgent need to develop an ultrasensitive sensing platform to achieve precise BMY analysis with a low detection limit and simpler workflow. In this work, we establish an encapsulated-enzyme-based BMY biosensing platform in which α-glucosidase is embedded in magnetic layered double hydroxide using a self-sacrificing template. The encapsulated enzyme has increased activity, robustness, and recyclability and was utilized for BMY detection via a cascade chromatic process. We found a detection limit for the quantification of BMY activity of 2.67 U/L with a broad range (5–400 U/L), fast response speed (10 min), and satisfactory specificity. We applied the biosensing platform to liquor starters to verify the capability of the assay in complicated fermentation samples. The proposed platform holds great promise as an efficient and simple method for enzymatic bioactivity monitoring in food manufacturing, biopharmaceutical processing, and clinical laboratory tests.
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CARBOHYDRATE POLYMERS
·
2024
·
IF 10.7
Shiqing Chen,Mingyang Bai,Qihang Wang,Xinyi Li,Jiawei Shao,Sheldon Q. Shi,Wenrui Zhou,Jinfeng Cao,Jianzhang Li
The development of a biomass adhesive as a substitute for petroleum-derived adhesives has been considered a viable option. However, achieving both superior bonding strength and toughness in biomass adhesives remains a significant challenge. Inspired by the human skeletal muscles structure, this study reveals a promising supramolecular structure using tannin acid (TA) functionalized poly-β-cyclodextrin (PCD) (TA@PCD) as elastic tissues and chitin nanocrystals (ChNCs) as green reinforcements to strengthen the soybean meal (SM) adhesive crosslinking network. TA@PCD acts as a dynamic crosslinker that facilitates reversible host-guest interactions, hydrogen bonds, and electrostatic interactions between adjacent stiff ChNCs and SM matrix, resulting in satisfactory strength and toughness. The resulting SM/TA@PCD/ChNCs-2 adhesive has demonstrated satisfactory wet and dry shear strength (1.25 MPa and 2.57 MPa, respectively), toughness (0.69 J), and long-term solvents resistance (80 d). Furthermore, the adhesive can exhibit desirable antimildew characteristics owing to the phenol hydroxyl groups of TA and amino groups of ChNCs. This work showcases an effective supramolecular chemistry strategy for fabricating high-performance biomass adhesives with great potential for practical applications.
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RSC Advances
·
2017
·Vol. 7
·期 43
·26633-26639
·
IF 3.108
Chenxi Song,Shubiao Zhang,Quan Zhou,Lei Shi,Linying Du,Defu Zhi,Yinan Zhao,Yuhong Zhen,Defeng Zhao
β-NaYF4:Yb,Er upconversion nanoparticles (UCNPs) were synthesized by a one-pot solvothermal method. The UCNPs were characterized through X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) to prove that they possessed hexagonal crystal phase with uniform particle size distribution. The cationic solid lipid nanoparticles (CSLNs) were then obtained by coating the UCNPs with a lipid. Further analysis by FTIR, XRD and TEM indicated the lipid can successfully coat UCNPs, and the coating process had no obvious influences on morphology and crystallization of the UCNPs. Furthermore, the CSLNs were used for bioimaging in cells and delivering small interfering RNA (siRNA). Cellular bioimaging and upconversion luminescence studies clearly demonstrated that the CSLNs could effectively enter into cells with the help of the lipid. Silencing assays and cytotoxicity in A549 cells convincingly showed that the CSLNs could effectively deliver siRNA and possessed low cytotoxicity and good biocompatibility. Thus, the bifunctional CSLNs could be used as a potential candidate in bioimaging and therapeutic applications.
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ANALYTICA CHIMICA ACTA
·
2024
·
IF 5.7
Yajie Zhang,Zhuhui Chen,Aoli Ye,Pei Chen,Anqi Wu,Eric Abdon Andriniaina,Linjun You,Deli Xiao
Background β-nicotinamide mononucleotide stands out as an essential breakthrough in “anti-aging” and consistently leads the list of top-selling nutritional supplements in terms of quantity. As the metabolites of β-nicotinamide mononucleotide, the detection of nicotinamide and N 1 -methylnicotinamide is of great significance for evaluating the nutritional effect of dietary supplements of β-nicotinamide mononucleotide. However, due to the extremely low concentration of nicotinamide and N 1 -methylnicotinamide in vivo and the serious matrix interference in biological samples, there is an increasing demand for materials and methods of pre-treatment. Results In this study, Fe 3 O 4 @hydroxypropyl methyl cellulose@dodecylbenzenesulfonic acid magnetic fluid was synthesized for the first time, and it was used as pretreatment material to detect nicotinamide and N 1 - methylnicotinamide in urine samples by high performance liquid chromatography. Compared with other adsorption materials, Fe 3 O 4 @hydroxypropyl methyl cellulose@dodecylbenzenesulfonic acid nanoparticles are a kind of uniform magnetic fluid. Furthermore, they have more types and quantities of interaction sites (electrostatic interactions, hydrophobic interactions, hydrogen bonding interactions, and π-π interactions), so they own greater adsorption capacity. When the pH of the solution is 4, they can be adsorbed quickly within 10 s. The method successfully detected trace nicotinamide and N 1 -methylnicotinamide in urine samples in the linear range of 0.1–80 μg mL −1 , the low detection limits were 0.30 ng mL −1 and 1.5 ng mL −1 respectively, and the quantification limits were 1.0 ng mL −1 and 5.0 ng mL −1 , respectively. At the same time, the standard urine samples of nicotinamide and N 1 -methylnicotinamide showed satisfactory recovery rate 94.50–109.1 %. The results indicated that the established method can accurately and quantitatively determine trace nicotinamide and N 1 -methylnicotinamide in urine samples. Significance Consequently, low concentration of β-nicotinamide mononucleotide metabolites can be detected simultaneously, and the interference can be eliminated during the detection process, which provides an efficient and convenient pretreatment method and a rapid and sensitive detection method for the analysis of β-nicotinamide mononucleotide metabolites. What's more, it has a wide application prospect in the analysis of other similar metabolites in biological samples.
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MOLECULES
·
2024
·Vol. 29
·期 10
·2363
·
IF 4.2
Tao Li,Mingzu Zhang,Jinlin He,Peihong Ni
Graft copolymers have unique application scenarios in the field of high-performance thermoplastic elastomers, resins and rubbers. β-myrcene (My) is a biomass monomer derived from renewable plant resources, and its homopolymer has a low glass transition temperature and high elasticity. In this work, a series of tapered copolymers P(My-co-AMS)k(k = 1, 2, 3) were first synthesized in cyclohexane by one-pot anionic polymerization of My and α-methyl styrene (AMS) using sec-BuLi as the initiator. PAMS chain would fracture when heated at high temperature and could endow the copolymer with thermal degradation property. The effect of the incorporation of AMS unit on the thermal stability and glass transition temperature of polymyrcene main chain was studied. Subsequently, the double bonds in the linear copolymers were partially epoxidized and hydroxylated into hydroxyl groups to obtain hydroxylated copolymer, which was finally used to initiate the ring-opening polymerization (ROP) of ε-caprolactone (ε-CL) to synthesize the graft copolymer with PCL as the side chain. All these copolymers before and after modifications were characterized by proton nuclear magnetic resonance (1H NMR), gel permeation chromatography (GPC), thermogravimetry analysis (TGA), and differential scanning calorimeter (DSC).
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Chemical Biology & Drug Design
·
2024
·Vol. 103
·期 1
·e14434
·
IF 3.2
Liyang Liu,Wusong Xue
Heaps of studies have verified the effects of thalidomide (THA) on colorectal cancer (CRC). Howbeit, the corresponding mechanism awaits illustration, which is the foothold of this study. Following the treatment of 0, 1.94, 7.75, or 19.36 μM THA, CRC cell viability, apoptosis, migration, and invasion were evaluated by methyl tetrazolium, flow cytometry, wound-healing, and transwell assays. Homeobox B7 (HOXB7) expression in CRC was analyzed and detected by bioinformatics analysis, quantitative real-time PCR or western blot. After the corresponding transfection or treatment with inhibitor of catenin-responsive transcription-3 (iCRT-3), abovementioned CRC cell biological behaviors as well as expression levels of HOXB7 and β-catenin were evaluated. 7.75 and 19.36 μM THA dwindled CRC cell viability, migration, and invasion, and facilitated apoptosis. HOXB7 upregulation was detected in CRC cells, which promoted the viability, migration, invasion, and β-catenin expression, and weakened the apoptosis of CRC cells. Also, HOXB7 upregulation counteracted the effects of THA on CRC cells. iCRT-3 restrained β-catenin expression, viability, migration, and invasion, whereas promoting the apoptosis of CRC cells. In addition, iCRT-3 antagonized the effects of overexpressed HOXB7 on CRC cells. THA inhibits the migration and invasion of CRC cells, which is achieved by suppressing HOXB7-mediated activation of Wnt/β-catenin signaling pathway.
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CRYSTENGCOMM
·
2024
·Vol. 26
·期 39
·5591-5598
·
IF 2.6
Piyu Gong,Mengwen Hu,Yihao Zheng,Shuo Tao,Haibo Li,Suyuan Zeng,Lei Wang
Owing to the synergistic effect between two metals and a high oxidation state, β-ZnMoO4 shows a high theoretical specific capacity and acts as one active material for the design and construction of lithium-ion batteries. In this paper, β-ZnMoO4 structures were formed by one hydrothermal process and characterized with XRD, SEM, Raman and XPS. The electrochemical performance tests demonstrate their excellent lithium storage capacity and cycling stability. At a current density of 2.0 A g−1, the reversible capacities of two formed β-ZnMoO4 microstructures were maintained at 665.5 and 704.6 mA h g−1 after 500 cycles. These characteristics prove that β-ZnMoO4 structures show interesting application prospects in portable energy storage devices.
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PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
·
2025
·
IF 4
Li Zhang,Yizhong Huang,Zhuaquan Xiao,Xuezhen Feng,Ji Zhang,Shangxing Chen,Haohua He,Shengliang Liao,Zongde Wang,Hongyan Si
Rhizoctonia solani ( R. solani ) is a phytopathogen that extensively affects crops, leading to plant diseases and reducing crop yields, which jeopardizes food security. β-pinene is a major component of turpentine oil and serves as a lead compound for developing new fungicides. Herein, β-pinene derivatives containing quaternary ammonium scaffold were synthesized in our laboratory, exhibiting broad-spectrum antifungal activity, especially compound bis-hydronopyl dimethyl ammonium bromide ( b-HDAB ). This study aimed to investigate the potential antifungal mechanism of b-HDAB against R. solani . The b-HDAB displayed promising antifungal activities in vitro (EC 50 = 10.20 mg/L and EC 90 = 18.43 mg/L). Its in vivo curative effects (59.82 %) at a dose of 500 mg/L were as remarkable as those of the positive control of validamycin·bacillus (60.58 %). Mechanistically, b-HDAB altered the normal morphology of R. solani mycelium and disrupted its ultrastructure. Meanwhile, b-HDAB increased the relative electrical conductivity of R. solani mycelium, leading to leakage of nucleic acids and proteins from the mycelium. In addition, b-HDAB inhibited the tricarboxylic acid cycle (TCA)-related enzymes, and b-HDAB might exhibit favorable binding stability, potentially through the formation of a pi-cation interaction with the arginine residue (RP357) of pyruvate dehydrogenase (PDH). Metabolomics analysis demonstrated that the content of unsaturated fatty acids of R. solani increased after treatment with b-HDAB , and transcriptomic analysis indicated that b-HDAB destroyed the energy metabolism. These results might guide the development of b-HDAB as an alternative antifungal agent.
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Nano Energy
·
2024
·
IF 16.8
Yang Wang,Chaogang Ban,Yajie Feng,Jiangping Ma,Junjie Ding,Xiaoxing Wang,Lujie Ruan,Youyu Duan,Mikhail G. Brik,Liyong Gan,Xiaoyuan Zhou
Rational design of highly efficient photocatalysts for CO 2 conversion into carbonaceous fuels is of great significance to mitigate the global greenhouse effect and energy shortage problem. Among numerous materials studied for this purpose, the carbon nitride (g-C 3 N 4 ) has been widely used in photocatalytic CO 2 reduction (PCR) due to its decent optical properties, low cost and environment friendliness. However, its wide use still remains a substantial challenge due to inefficiency of the active site and rapid recombination of photogenerated electrons and holes. Herein, we suggest a Z-scheme system of nitrogen vacancies g-C 3 N 4 /β-Bi 2 O 3 heterojunction photocatalyst based on self-assembly of nitrogen vacancies in g-C 3 N 4 nanosheets and β-Bi 2 O 3 micro-flowers, yielding an enhanced CO evolution rate of 30.56 μmol·g −1 ·h −1 under the simulated solar light without any cocatalysts and sacrificial agents. Our detailed studies indicate that the promoted PCR performance originates from the stronger adsorption capability of the *COOH intermediates due to the cleavage of the C-C bond in nitrogen vacancies g-C 3 N 4 (N V -C 3 N 4 ), turning the most endothermic step from the formation of *COOH intermediates to *CO. Moreover, the unique Z-scheme feature can efficiently facilitate the separation of photoelectron-hole pairs and enhance redox capability by optimizing the energy band structure. To sum up, this work provides deep insights and guidelines for rational design of highly efficient Z-scheme heterojunctions catalysts for CO 2 photoreduction to solar fuels.
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CARBOHYDRATE RESEARCH
·
2025
·
IF 2.5
Chunlin Gou,Ziqing Weng,Xiaoshuang Dai,Jianpeng Liu,Ke Mei,Bin Sun,Neng Qiu
To address the ecological and health risks associated with residual tetracycline hydrochloride (TCH) in water, a green-synthesized adsorbent composed of β-cyclodextrin (β-CD), citric acid (CA), and polyethylene glycol (PEG) was developed for the effective removal of TCH from wastewater. The synthetic parameters were optimized, and the resulting PEG-CA-β-CD MOF was characterized by FT-IR, XRD, and SE. TGA analysis indicated an increase in the thermal stability. The maximum adsorption capacity of PEG-CA-β-CD MOF for TCH was 221.6 mg/g at pH = 4. Adsorption kinetics were well-described by the Elovich equation model, while the Freundlich isothermal model accurately described the equilibrium data adsorption Thermodynamic analysis revealed that the adsorption process was endothermic and spontaneous. Furthermore, the adsorbent maintained 84 % of its initial adsorption capacity after four reuse cycles. Analysis using zeta potential, FT-IR, and XPS confirmed that the possible adsorption mechanism of TCH mainly involves electrostatic interactions, hydrogen bonding, and cavity encapsulation. Finally, simulated wastewater experiments showed that PEG-CA-β-CD MOF was able to adsorb TCH efficiently even in the presence of other pollutants. Overall, due to its green synthesis process, low cost, ease of regeneration, and multi-mechanistic adsorption capability, the PEG-CA-β-CD MOF exhibits significant potential for TCH removal in wastewater treatment.
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Food Chemistry-X
·
2025
·
IF 8.2
Weijun Chen,Hui Hou,Jiaxin Han,Xinhui Wang,Yuncheng Li,Fanbing Meng,Donghong Liu,Xiaoying Guo
A ternary covalent complex was prepared by conjugating whey protein isolate (WPI)-(−)-epigallocatechin-3-gallate (EGCG) covalent complex with gum acacia (GA). A blue shift in the amide A band and decreased intensity of amide bands in the Fourier transform infrared spectroscopy spectra, and an increase in molecular size confirmed the covalent linkage. It was utilized to stabilize β-carotene emulsion. The freeze–thaw, ionic strength, thermal and pH stability of emulsions were enhanced by conjugation with GA. Compared with WPI, the WPI-EGCG covalent complex and its mixture with GA, the ternary covalent complex used as an emulsifier more effectively inhibited the degradation of encapsulated β-carotene under ultraviolet light irradiation and thermal treatment. The stability of the emulsion during simulated gastrointestinal digestion and the in vitro bioaccessibility of BC also significantly ( p < 0.05) increased after conjugation with GA. These findings could provide insights into the design of promising and effective food-grade emulsion delivery systems.
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