RSC Advances
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2025
·Vol. 15
·期 10
·7869-7875
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IF 4.6
Zheng Chen,Shuting Wang,Hongyan Zhou,Suyuan Zeng
Molybdenum carbide (Mo2C) has emerged as a subject of considerable research interest as an intrinsically Pt-like electronic and cost-effective alternative to platinum-based catalysts for the sustainable hydrogen evolution reaction (HER). However, a high carbonization temperature can easily cause the agglomeration of nanoparticles. Therefore, we employed a zeolitic imidazolate framework (ZIF)-assisted synthesis strategy, obtaining Mo2C/CN-T nanoparticles by calcining the precursor Mo-ZIF at high temperature and low pressure. Utilizing the carbon defects, nitrogen doping, and nanosized active sites provided by ZIFs, the as-prepared electrocatalyst enables swift catalytic reaction kinetics and superior activity stability. The as-prepared Mo2C/CN-850 manifests a high HER catalytic activity in acid and alkaline media with a small overpotential of 97 and 117 mV at 10 mA cm−2, respectively and good stability at the industrial current density above 200 mA cm−2.
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ACS Applied Polymer Materials
·
2024
·
IF 4.4
Liuxin Yang,Pengfei Ren,Dandan Wei,Min Liang,Li Xu,Yinghua Tao,Guanhua Jiao,Tianzhu Zhang,Qianli Zhang
Temperature-responsive poly(N-isopropylacrylamide) (PNIPAM) polymers have been studied in many fields due to their “on–off” adjustable properties under temperature stimulation. In this work, the “on–off” mechanism for poly(N-isopropylacrylamide-co-dopamine methacrylamide) (PNIPAM-co-DMA) microgels for cell culture and nonenzymatic cell harvest was explored. Thermoresponsive surfaces were developed on silica wafers using microgels with different DMA contents using a simple spin-coating method. Experiments showed that the microgels showed an “on” state above the lower critical solution temperature (LCST), and PNIPAM-co-DMA (PND) microgels shrank to expose catechol groups for enhanced cell adhesion and proliferation. Conversely, the microgels showed an “off” state below LCST, and the hydrophobic and cell-repellent properties of DMA contributed to the rapid hydration of microgels for accelerated cell disassociation. The developed microgels presented DMA content and distribution-related cell detachment efficiency, with PND (100:0.5) and PND (100:2) showing better results. The failure of cell harvest caused by too much DMA restricted the shrinkage and swelling of microgels due to the strong hydrogen-bonding adhesion of catechol moieties for PND (100:10). Overall, the presented strategy exhibits a wide-ranging utility to construct thermoresponsive surfaces with “on–off” functionalization by introducing catechol chemical monomers.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-18
·
IF 15.7
Li Mingyang,Song Xiaorong,Tu Haixia,Sun Jie,Deng Yuanyuan,Wang Bing,Cai Yuhan,Wang Yulian,Li Bin,Wang Yue,Zhang Xiangzheng,Wei Dong,Yang Xiaoyu,Guo Yueshuai,Li Xiang,Gu Jie,Ni Jie,Zhou Yifan,Gu Zhongze,Xie Zhuoying,Li Yan,Guo Xuejiang
Extracellular vesicles (EVs) carry complex glycoproteins critical mediators of disease progression and hold great potential for liquid biopsy applications. However, their low abundance presents significant analytical challenges. This study develop a versatile platform for EV N-glycoproteomic analysis (EVGpro), which enables tandem EV capture, EV protein digestion, and enrichment of N-glycopeptides. Functionalized magnetic nanochains with cell-penetrating peptides (octa-arginine, R 8 ) enable efficient EV isolation, followed by on-chain hydrolysis to expose PEG 2000 for ultrasensitive glycopeptide enrichment. The streamlined EVGpro platform identified up to 17 times more EV glycoproteins than ultracentrifugation across seven biofluids, profiling 398 EV glycoproteins from just 1 μL tear. Applied to seminal plasma, EVGpro uncover disease-specific glycoprotein signatures and identified previously unreported subtypes of asthenozoospermia. This robust and scalable approach advances the sensitive detection of disease biomarkers and molecular subtypes from diverse biofluids to enable precision medicine.
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WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
·
2025
·Vol. 41
·期 8
·1-13
·
IF 4.2
Jiang Cheng,Li Luli,Li Jialu
Chitinolytic enzymes are capable of hydrolyzing the cell walls of pathogenic fungi, disrupting the exoskeletons of insect pests, and producing N-acetyl-β-D-glucosamine oligomers or monomers. In this study, a new β-N-acetylhexosaminidase gene encoding an enzyme from glycoside hydrolase family 20 (GH 20) was identified from the biocontrol fungus Chaetomium globosum W7. The corresponding protein was designated CgNagase20 and was heterologously expressed in Escherichia coli . The molecular mass of the protein was approximately 66.7 kDa, and this enzyme exhibited maximal activity at 55 °C and pH 4.0. Heavy metal ions, particularly Fe 3+ , Ag + , and Hg 2+ , were found to strongly inhibit CgNagase20 activity. CgNagase20 exhibits typical substrate specificity of β-N-acetylhexosaminidase (EC 3.2.1.52), acting on N-acetylglucosides and N-acetylgalactosides, with monosaccharides as the sole end products. The Vmax and Km values for CgNagase20 when acting on 4-nitrophenyl N-acetyl-β-D-glucosaminide (pNP-βGlcNAc) were calculated to be 118.85 µmol/min/mg protein and 1.59 mM, respectively. Additionally, CgNagase20 demonstrated antifungal activity, significantly inhibiting spore germination and hyphal growth of Fusarium sporotrichioides , the causative agent of potato dry rot. In conclusion, CgNagase20 represents the first β-N-acetylhexosaminidase identified and characterized from C. globosum , with potential applications in both the industrial and agricultural sectors.
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JOURNAL OF THE INDIAN CHEMICAL SOCIETY
·
2025
·
IF 3.4
Wei Shen,Zilong Yang,Xiaolin Guo,Hongxiao Jin,Wenxiang Chai,Hongliang Ge,Dingfeng Jin
Amino acid ionic liquids (AAILs) are potential green substitutes of aqueous amine solutions for carbon dioxide (CO 2 ) capture. In this study, we prepared three amino acid ionic liquids, constructed from tetrabutylphosphine hydroxide in combination with glycine, histidine, and arginine. We have conducted a comprehensive study on the CO 2 absorption capacity of structures containing single, double, and triple N–H groups. The solubility of CO 2 in [P 4444 ][Gly], [P 4444 ][His] and [P 4444 ][Arg] were measured experimentally over a temperature range of 30–110 °C and up to a pressure of 0.75 MPa. The results indicate that the solubility of carbon dioxide in amino acid ionic liquids decreases with increasing temperature, while it increases with increasing pressure. The optimal CO 2 absorption conditions of three amino acid ionic liquids were determined to be 50 °C, 0.75 MPa. Moreover, CO 2 absorption capacity of three amino acid ionic liquids followed the order: [P 4444 ][Arg] > [P 4444 ][His] > [P 4444 ][Gly]. Studies on the recycling and regeneration of amino acid ionic liquids verified their reusability in the process and confirmed that the reaction between AAILs and CO 2 could be reversed at 140 °C. Finally, the recycle capacity and CO 2 removal efficiency of [P 4444 ][Gly], [P 4444 ][His] and [P 4444 ][Arg] were evaluated.
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GREEN CHEMISTRY
·
2024
·Vol. 26
·期 24
·12019-12033
·
IF 9.3
Yi Li,Qiancheng Liu,Qian Zhang,Xiaoxiao Li,Yang Yang,Pan Wang,Kui Li,Ying Li,Fei Zhong,Qi Liu,Yun Zheng,Xulin Yang,Peng Zhao
Phthalonitrile (PN) resins, renowned for their highly conjugated heteroaromatic N-rich structures, are exemplary precursors for the fabrication of porous materials. However, the conventional synthesis of PN is marred by the generation of the hazardous KNO2 by-product that poses significant environmental, safety, and health hazards. In this study, we introduce an innovative approach to PN synthesis, utilizing 4-chlorophthalonitrile as the starting material. This “utilize rather than create” strategy employs the reaction product (RPH) as the precursor and the by-product (KCl) as the template for the synthesis of porous carbon (RKC). The formation mechanism of RKC is elucidated through TGA/FTIR and TGA/MS analysis. The resultant RKCs exhibit exceptional characteristics suitable for supercapacitor applications, including hierarchical micro-/meso-/macropores, an extensive specific surface area, a high N-doping level, and diverse N species (N-6, N-5, N-Q). RKC@600 achieves a remarkable specific capacitance of 300 F g−1 at 1 A g−1 and demonstrates impressive cycling stability with a retention of 96.1% capacitance after 10 000 cycles at 10 A g−1. This research promotes the advancement of green and sustainable PN chemistry, driving forward the evolution of PN-based functional materials.
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POLYMER
·
2024
·
IF 4.1
Huiting Yu,Xi Sun,Zheng Liu,Heguo Han,Jianhang Qiu,Qifeng Zhang,Yuxuan Sun,Shenghai Li,Suobo Zhang
Semi-crystalline poly (ether ketone) (PEK) materials with intrinsic solvent resistance are ideal materials for the preparation of organic solvent nanofiltration (OSN) membranes. Although some precursor materials have been developed for soluble processing through group protection strategies, these precursors are difficult to hydrolyze, limiting their practical applications. In this work, we designed an easily hydrolyzable N-cyclohexyl-poly (ether ketone ether imide) (CYH-PEKEI) precursor that could be converted to PEK by acid treatment at 80°C within 1 h. The results showed that the prepared membrane was stable in various organic solvents, with a permeance of 1.29 L m −2 h −1 bar −1 in N, N-Dimethylformamide (DMF), a molecular weight cutoff of 320 g/mol, and good long-term operational stability. Additionally, the membrane demonstrated excellent aging resistance during variable temperature DMF operation. This work has stimulated the potential of PEK membranes for OSN applications by optimizing the precursor structure.
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ENVIRONMENTAL RESEARCH
·
2025
·
IF 7.7
Yao Fang,Yuanjun Tang,Guoneng Li,Jun Dong,Chao Ye,Zhongming Bu,Wenwen Guo
The efficient removal of fluoroquinolone antibiotics from water is critical for water pollution control. In this study, a novel self-nitrogen doped porous biochar (KBC) was synthesized using waste peanut meal as a precursor, combined with high-temperature pyrolysis (900 °C) and an activating agent (C 2 H 2 K 2 O 5 ) at an optimal mass ratio of 1:2. The KBC exhibited excellent adsorption capacity for levofloxacin (LEV) with the maximum capacity of 717.87 mg g −1 (at 0.15 g L −1 ). The adsorbents demonstrated rapid adsorption kinetics, achieving 83.36 % of total adsorption within 2 h, and exhibited pH-dependent adsorption behavior, with optimal performance at pH = 9. Thermodynamic studies indicated that the adsorption process was spontaneous and endothermic. The adsorption isotherm followed the Langmuir model, suggesting monolayer chemisorption as the dominant mechanism. Additionally, the pseudo-second-order kinetic model further confirmed the involvement of chemical interactions. Material characterization and density functional theory (DFT) simulations were employed to reveal the underlying adsorption mechanisms: (1) micropore filling-dominated physical adsorption (BET surface area = 2119.96 m 2 g −1 ); (2) hydrogen bonding and π-π electron donor-acceptor interactions between oxygen-containing functional groups on the KBC surface and LEV molecules; (3) DFT calculations revealed that the adsorption energy of anionic LEV (−321.72 kJ mol −1 ) was significantly higher than that of neutral and cationic forms, consistent with the experimental pH-dependent trend; and (4) DFT-optimized configurations demonstrated strong interactions between LEV and the biochar with a bond distance of 2.0 Å, providing atomic-level evidence for adsorption stability. These findings offer practical insights into the valorization of agricultural waste and advanced strategies for water remediation.
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POLYMER DEGRADATION AND STABILITY
·
2025
·
IF 7.4
Jirui Qu,Yusheng Tong,Yujiao Bi,Wenbo Sun,Yanyue Shi,Zexuan Zhao,Zhihui Liu,Shaofeng Wang,Lei Liu,Xilei Chen,Chuanmei Jiao
In recent years, P-N based hybrids flame retardants have received more and more attention in the field of fire safety due to their synergistic effect in the gas and condensed phases, which makes it easy to achieve efficient flame retardancy. However, their flame retardant mechanism in the gas phase rests more on the increase of non-flammable gases than on the conversion of harmful gases to harmless gases, and their hybrids are often not sufficiently stable. Therefore, in this study, P-N hybrids were encapsulated and modified using MXene, which has high thermal stability and outstanding catalytic ability, to prepare a novel flame-retardant hybrid, MDAPP, which was incorporated into rigid polyurethane foam (RPUF) to achieve more efficient fire safety performance. The results showed that MDAPP significantly enhanced the fire safety properties of RPUF composites. Specifically, RPUF-2.0MDAPP resulted in 40.98%, 63.16, and 60.00% decreases in total heat release (THR), total smoke release (TSP), and CO production rate (COPR) of RPUF, respectively. Moreover, the system also achieves synergistic flame retardant effects in the gas and condensed phases. At the same time, RPUF-2.0MDAPP has excellent thermal shielding performance, with a temperature reduction of 88.14% compared to RPUF in a fire source heating test when placed in a vertical position. In addition, the compressive strength and hydrophobicity of RPUF-2.0MDAPP have been improved to ensure its longevity in complex environments. This study proposes a solution to the problem of reducing the fire risk of RPUFs and promotes the widespread use of RPUF.
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ELECTROCHEMISTRY COMMUNICATIONS
·
2025
·
IF 4.2
Lin Wang,Hai Yu,YaXin Wang,Miao Chun,QianQian Lei,XinPing Yao,XiaoChen Yao,Xin Wei,JianGuo Lv,Yan Xue,JingWen Zhang,SiWen Zhou,DanDan Qu
This study synthesized p-type Cu 2 O using an electrodeposition method and firmly attached it to TiO 2 nanosheets based on fluorine-doped tin oxide (FTO) substrates, forming a dense film that serves directly as a photoanode for photoelectrochemical (PEC) water splitting. Characterization techniques such as XRD, SEM, XPS, and UV–Vis confirmed the successful deposition of Cu 2 O on the TiO 2 nanosheets, forming a p-n heterojunction structure. The incorporation of Cu 2 O effectively broadened the light absorption range of TiO 2 , with a cut-off wavelength red-shifting to 537 nm, enabling it to absorb more visible light. Photoelectrochemical tests showed that under illuminated unbiased conditions, the photocurrent density of Cu 2 O-TiO 2 reached 0.3 mA/cm 2 , which is 7.5 times that of TiO 2 . After applying a small bias (0.5 V), the photocurrent density further increased to 2.1 mA/cm 2 , 5.2 times that under unbiased conditions, indicating that the introduction of electricity effectively accelerated the separation efficiency of photo-generated carriers. The Cu₂O-TiO₂ heterojunction exhibited significantly higher photocurrent density (measured by LSV) and charge transfer efficiency (evaluated by EIS) than pure TiO₂. This research provides new insights for PEC water splitting technology and serves as a reference for designing high-performance photocatalysts.
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2025
·
IF 2.1
Yue Wang,Wenxiu Li,Saisai Wang,Pengfei Wang,Tao Zhang
Ionic liquids (ILs) exhibited enhanced extraction performance compared with traditional organic solvents in azeotropic separation processes. In this paper, three kinds of ILs: 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIM][BF4]), 1-butyl-3-methylimidazolium diethylphosphate ([BMIM][DEP]), and 1-hexyl-3-methylimidazolium hexafluorophosphate ([HMIM][PF6]) were considered as extractants for separate n-heptane and acetone. The effect of temperature (298.15, 303.15, and 308.15 K) on the selectivity and distribution coefficients was then investigated. Liquid–liquid equilibrium (LLE) experiments demonstrated that three ILs proved the separation efficiency for acetone. The experimental data were then regressed and validated using the Othmer–Tobias equation and the Hand equation. In addition, the NRTL (nonrandom two liquids) model was used to correlate the LLE experimental data, and the NRTL parameters are verified through the “GMcal_TieLinesLL” tool. Finally, molecular interaction mechanisms were further elucidated through surface electrostatic potential mapping (ESP) and an independent gradient model based on Hirshfeld partition analysis (IGMH) analysis. This research establishes a theoretical framework for industrial-scale separation of ketone/alkane mixtures while providing valuable insights into structure–property relationships of ILs in separation processes.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Shuaishuai Guo,Fangyuan Chang,Guowen Peng,Ping Cao,Wenjie Lu,Yanlu Lu,Jie Jiang,Qingyan Zhang,Qingyi Zeng
To meet the pressing demands of sustainable nuclear energy development and radioactive pollution mitigation, the development of high-efficiency adsorbents for uranium extraction from real wastewater is paramount. In this study, a MNP@NHCS adsorbent was engineered through a carrier-supported strategy involving in-situ growth of δ-MnO 2 nanoplates (MNP) on N-doped hollow carbon spheres (NHCS). Material characterization confirmed that NHCS suppresses δ-MnO 2 agglomeration and enhances the specific surface area to 218.22 m 2 /g (3.5-fold higher than pristine δ-MnO 2 62.28 m 2 /g). Batch experiments demonstrated exceptional performance: excellent U(VI) adsorption capacity (423.61 mg/g), outstanding selectivity ( K d = 1.9 × 10 5 mL/g), robust recyclability (>95 % removal over 8 adsorption-desorption cycles), and real wastewater breakthrough (95 % uranium recovery rate: 0.21 mg U(VI) / 100 mg ads.). Comprehensive characterization, multi-model fit analysis and in-situ zeta potential monitoring revealed that U(VI) capture follows a spontaneous, endothermic monolayer process driven by coordination-electrostatic synergy between Lewis acid-base sites (Mn-O, -OH, and -NH 2 ) and electrostatic attraction. This work provides an efficient, stable, and eco-friendly adsorbent for real wastewater treatment in the nuclear industry, advancing uranium resource recovery and sustainable nuclear energy development.
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