ACS Applied Nano Materials
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2024
·
IF 5.3
Yapeng Yao,Xiaodong Gou,Wei Liu,Zihang Liang,Jiangbo Zhang,Zhongliang Ma
Integrating energetic materials into microelectromechanical system (MEMS) to enhance their energy output characteristics has shown extensive potential across aerospace, defense, and civilian applications. Within this study, the MEMS compatible Cu/DNBT (DNBT = [5,5′-dinitro-3,3′-bi(1,2,4-triazole)]) and Cu/DNBT@nano-Al energetic films were successfully synthesized on the copper substrate using an electrochemical method and a drip coating method. The scanning electron microscope (SEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), differential thermal analyses (DTA), and a pulse laser ignition test were used to analyze the morphology, composition, thermal performance, and ignition properties of the prepared samples. The findings indicate that the prepared Cu/DNBT and Cu/DNBT@nano-Al energetic films exhibit a nanostructure, and their morphology can be effectively regulated via modifications to the deposition voltage, deposition time, and aluminum plating frequency. Furthermore, the energetic properties of Cu/DNBT@nano-Al films can be adjusted after the deposition of nano-Al. Their heat release, flame height and ignition duration can reach up to 1823.1 J·g–1, 13.5 mm, and 400 μs, respectively. These findings suggest that Cu/DNBT@nano-Al energetic films being a prime contender for initiating powders in MEMS pyrotechnics. In summary, this work offers valuable insights into the integration and application of energetic materials in MEMS ignition devices.
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Advanced Composites and Hybrid Materials
·
2024
·Vol. 8
·期 1
·1-19
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IF 23.2
Ye Fangdie,Ye Chen,Zhao Yufeng,Li Weijian,Zhang Jinhao,Ou Yuxi,Chen Ziang,Cheng Zhang,Zhang Jing,Ali Shujaat,Qureshi Omer Salman,Liu Yufei,Dai Xiangpeng,Huang Hang,Jiang Haowen
Bladder cancer (BLCA), particularly due to the high recurrence and progression rates of non-muscle-invasive bladder cancer (NMIBC), is a significant global health challenge. Current treatments, such as Bacillus Calmette-Guérin (BCG) immunotherapy and intravesical chemotherapy, often cause substantial side effects and exhibit limited efficacy, highlighting the urgent need for novel therapeutic strategies. Single-cell spatial transcriptomic advancements have identified cuproptosis as a critical pathway in BLCA, presenting a promising target for treatment. In this study, these insights were leveraged to design Cu-VT nanoparticles (NPs), an innovative composite material that combines the unique properties of copper ions and the natural flavonoid vitexin, to induce cuproptosis. Cu-VT NPs could effectively induce apoptosis and oxidative stress in BLCA cells concurrently modulating the immune response within the tumor microenvironment. Comprehensive in vitro and in vivo experiments demonstrated that Cu-VT NPs significantly inhibited tumor growth and reduced lung metastasis through cuproptosis induction. This dual-function composite material enhances therapeutic efficacy and minimizes side effects, showcasing its potential as a revolutionary treatment for BLCA. Our findings highlight the transformative potential of Cu-VT NPs in the context of BLCA treatment, establishing a new paradigm in the use of composite materials for the treatment of advanced cancer.
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Journal of Cleaner Production
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2024
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IF 9.7
Xiaolu Sun,Linhua Jiang,Ning Duan,Guangbin Zhu,Yanli Xu,Hao Jin,Yong Liu,Rong Zhang
Currently, domestic and foreign copper smelting waste acid mainly employ sulfuration method to realize the separation of Cu(Ⅱ) and As(Ⅲ), facing the problem of unreasonable sulfidizing agent dosage and sulfidation time. If excessive sulfidizing agent dosage or overly long sulfidation time, it will lead to human health threat and large hazardous waste volume. If insufficient sulfidizing agent dosage or overly short sulfidation time, it will cause the waste of copper resources and substandard treatment solution. In this paper, the competitive sulfuration mechanism of Cu(Ⅱ)/As(Ⅲ) solution ( C (As(Ⅲ)) = 10 g/L) with different Cu(Ⅱ) concentrations is revealed, i.e., when C (Cu(Ⅱ)) ≥7 g/L, the sulfidation sequence of Cu(Ⅱ) and As(Ⅲ) follows the solubility product constant (Ksp); when C (Cu(Ⅱ)) ≤6 g/L, the precipitation process of Cu(Ⅱ)/As(Ⅲ) is dominated by the liquid-phase mass-transfer mechanism (ion diffusion). The sulfide precipitation of Cu(Ⅱ)/As(Ⅲ) is a co-deposition process. With the increase of sulfidizing agent dosage ( S/Cu ratio) and sulfidation time ( t ), the Cu(Ⅱ) concentration gradually decreases to reach complete removal, while the further increase of S/Cu ratio and t leads to the decrease of copper content in the sulfide precipitates. Finally, the methods are demonstrated that detected accurately Cu(Ⅱ) and As(Ⅲ) concentrations in a rapid and non-destructive manner. This work not only provides a novel perspective on the efficient separation of Cu(Ⅱ)/As(Ⅲ) in copper smelting waste acid, but also opens a unique approach for direct and rapid detection of Cu(Ⅱ)/As(Ⅲ) concentration during the sulfuration process. Hence, this research is a guide for the regulating means ( S/Cu and t ) in the actual multi-step sulfuration process of copper smelting waste acid treatment and electrorefining solution purification .
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ELECTROCHIMICA ACTA
·
2024
·
IF 5.5
Pengfei Wang,Kun Zhang,Jing Hu,Menglian Zheng
Zinc-based flow batteries hold great promise for grid-scale energy storage. However, the formation of zinc dendrites challenges their lifespan and safety. In this work, we devise a bimetallic organic framework material on carbon cloth (CuZn@MOF-CC) using a one-step dip coating method to address the dendrite issue. The prepared CuZn@MOF-CC promotes the creation of zincophilic sites on the electrode surface, facilitating smooth and uniform zinc deposition. Electrochemical csharacterizations and density functional theory (DFT) calculations reveal much stronger electronic interactions between CuZn@MOF and the zinc atoms compared to the commonly used anode material through an obvious electron interaction between the Zn atom and the Cu sites linked in the CuZn@MOF chain. By mitigating the zinc dendrite problem, this approach effectively improves the coulombic efficiency, cycle life, and safety of zinc-based flow batteries. The battery incorporating the prepared material demonstrates impressive stability, exceeding 450 cycles without dendrites at a high current density of 320 mA cm −2 , paving the way for efficient and reliable energy storage solutions and a sustainable future.
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JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
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2024
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IF 2.3
Xu Peng,Wang Shasha,Dai Wei,Shi Weishan,Xing Gang,Wang Zhaogui,Li Qun,You Chaoqun,Hao Dejun
Abstract Pesticides play a crucial role in modern agriculture, yet their widespread use poses a threat to the ecosystem by causing significant environmental damage. In an effort to address this issue, a novel nanopesticide delivery system was developed, utilizing a tannic acid (TA)-Cu combination deposited onto the surface of dendritic mesoporous silica nanoparticles (DMSNs). This innovative approach aims to enhance the efficiency of pesticide utilization. The process involved incorporating Tebuconazole (Teb) into DMSNs using the one-pot sol-gel method. Subsequently, a coating was applied through the sequential addition of TA and CuCl 2 to an aqueous dispersion of Teb@DMSNs. The resulting nanopesticide, named TA@Teb@DMSNs, exhibited a spherical shape and achieved an impressive Teb loading rate of nearly 26.6%. Kinetic studies on Teb release revealed that TA@Teb@DMSNs demonstrated characteristics conducive to controlled and sustained release. The adhesion quality of TA@Teb@DMSNs on Aesculus chinensis Bunge leaves was confirmed through a comparative study with Teb@DMSNs. Additionally, when compared to Teb suspension, TA@Teb@DMSNs exhibited superior antifungal activity against Fusarium esculenta wilt over an extended period. Consequently, the TA@Teb@DMSNs constructed in this research might be used as an efficient nanopesticide formulation for advancing the sustainable development of agriculture. Graphical Abstract A novel nanopesticide delivery system is prepared by depositing of tannic acid-Cu complex on dendritic mesoporous silica nanoparticles, which effectively improves the adhesion and effective time of pesticide on the leaf.
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LANGMUIR
·
2024
·
IF 3.7
Wei-Guang Xiong,Chang-Yong Li,Ranjith Kumar Kankala,Ai-Zheng Chen,Shi-Bin Wang
There has been a growing emphasis on facile preparation of binary heterogeneous composite materials. Leveraging the eco-friendly efficiency of supercritical CO2 technology, we achieved precise control over the influencing factors of mass transfer, enabling the accurate modulation of the resulting product morphology and properties. In the current study, CuxO/ZrOy composite materials were prepared using this technology and calcined to obtain electrode materials for the detection of cysteine (Cys). Essential comprehensive characterization techniques were employed to elucidate the heterojunction. The resulting electrode demonstrated a linear response to Cys within a concentration range of 0.5 nM to 1 μM, featuring a high sensitivity of 1035 μA·cm–2·μM–1 and a low detection limit of 97.3 nM. Thus, establishing a novel avenue for nonenzyme-based electrochemical sensors tailored for biologically active Cys detection through the implementation of a heterogeneous structure.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Yan Sun,Zhicheng Wang,Xiaohui Wu,Wen-Da Oh,Mingjie Huang,Tao Zhou
Molecular oxygen (O 2 ), a reactive oxygen species precursor, has great potential for water purification, but its spin-forbidden resistance hinders its direct involvement in the redox reactions of organic compounds under mild ambient conditions. In this study, a facile strategy was employed to synthesize sulfide-modified Fe-Cu bimetallic catalysts (FeCu-S) to enhance the activation efficiency of O 2 . The results showed that the FeCu-S material exhibited a tenfold increase in O 2 activation compared to that of the control group, primarily attributed to the increased specific surface area of the catalysts with an optimized Fe/Cu site distribution and promoted generation of Cu-containing crystalline phases (e. g., CuFeS 2 and CuO) to significantly enhanced the oxygen storage capacity. Moreover, such Cu-containing crystalline phases strengthened surface electron transfer, thus remarkably promoting the selective generation of singlet oxygen ( 1 O 2 ) for sulfamethoxazole (SMX) degradation. The FeCu-S/O 2 system maintained high activity after the fifth recycle with stable reaction pH and negligible leaching of Cu and Fe ions, also exhibited great performance in the advanced treatment of the real biological effluent and ultrafiltration effluent from landfill leachate, confirming its great potential for practical water purification applications.
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JOURNAL OF FOOD COMPOSITION AND ANALYSIS
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2024
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IF 4
Kai Zhang,Dan Hou,Dongping Wu,Yanxia Li,Xuemei He,Tingting Sun,Jianhua Xiong,Xiaoning Liao
Accurate detection of benzimidazole pesticide thiophanate-methyl (TM) is of vital importance due to its harm to environmental safety and human health. Herein, for the first time, we developed a sensitive nonenzymatic electrochemical sensor for TM detection based on multiwall carbon nanotubes (MWCNTs) functionalized bimetallic iron−copper organic frameworks (Fe/Cu MOF). The synthesized nanocomposites showed excellent electro-oxidation ability to TM owing to the synergistic effect between MWCNTs and Fe/Cu MOF. Fe/Cu MOF enhanced the specific surface area for MWCNTs and MWCNTs improved the conductivity for Fe/Cu MOF, which resulted in a nanocomposite with abundant catalytical active sites and superior conductivity, greatly amplifying the detection signal for TM. Under optimized conditions, the proposed sensor based on the composite presented a wide linearity from 0.3 nM to 200 nM which is wider than that of currently reported methods and a very low detection limit (LOD) of 0.1 nM far lower than the maximum residue levels (MRLs) enacted worldwide. Furthermore, the sensor showed good reproducibility, long-term stability and high anti-interference. Moreover, the sensor can be successfully employed for the determination of TM in apple and cucumber with good recoveries (80.96 %–105. 5 %), highlighting its excellent potential as an alternative to traditional techniques.
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JOURNAL OF INORGANIC BIOCHEMISTRY
·
2024
·
IF 3.8
Kehua Wang,Ling Wang,Zhuye Shang,Xingzhi Yang,Hongmei Li,Xiaochun Wang,Mingchang Zhu,Qingtao Meng
Copper(II) complexes are very promising candidates for platinum-based anticancer agents. Herein, three Cu (II) complexes ( 1 – 3 ) containing 1,8-naphthalimide ligands were synthesized and characterized by FT-IR, elemental analysis, ESI-MS and single crystal X-ray diffraction (complex 3 ). In addition, a control compound (complex 4 ) without 1,8-naphthalimide ligand was synthesized and characterized. The in vitro anticancer activity of the synthesized complexes against five cancer cell lines and one normal cell line was evaluated by MTS assay. The results displayed the antitumor activity of complexes 1 – 3 was controlled by the aliphatic chain length of ligands, their cytotoxicity was in the order 3 > 2 > 1 , giving the IC 50 values ranging from 2.874 ± 0.155 μM to 31.47 ± 0.29 μM against five cancer cell lines. Complex 4 showed less activity in comparison with complex 1 – 3 . Notably, complexes 1 – 3 displayed much higher selectivity (SI = 2.65 to 10.16) compared to complex 4 (SI = 1.0), indicated that the introduction of 1,8-naphthalimide group not only increased the activity of this series of compounds but also enhanced their specific selectivity to cancer cells. Compound 3 induced apoptosis in cancer cells and blocked the S-phase and G2/M of cancer cells. The interaction with DNA of complexes 3 and 4 was studied by UV/Vis spectroscopic titrations, competitive DNA-binding experiment, viscometry and CD spectra. The results showed that complex 3 interacted with DNA in an intercalating mode, but the interaction mode of compound 4 with DNA was electrostatic interaction.
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WATER RESEARCH
·
2024
·
IF 11.4
Yao Li,Wenhong Fan,Xiaolong Yang,Shu Liu,Ying Wang,Wen-Xiong Wang
Cosmetics and personal care products containing titanium dioxide nanoparticles (TiO 2 NPs) may enter aquatic environments, where the surface coatings of TiO 2 NPs may change with aging due to environmental factors such as light, and potentially affect their bioaccumulation and toxicity. This study examined how aging impacted the physicochemical properties of three commercially available TiO 2 NPs and subsequent influence on the bioaccumulation and toxicity of copper (Cu) in Daphnia magna ( D. magna ). We demonstrated that aging significantly affected the hydrophobicity of TiO 2 NPs, which affected their binding to water molecules and adsorption of Cu. Changes of bioaccumulation of TiO 2 NPs and Cu in D. magna ultimately affected the activities of intracellular antioxidant enzymes such as SOD, CAT, GSH-Px, and the transmembrane protein Na + /K + –ATPase. Molecular docking calculations demonstrated that changes of activities of these biological enzymes were due to the interaction between TiO 2 NPs, Cu, and amino acid residues near the sites with the lowest binding energy and active center of the enzyme. Such effect was closely related to the hydrophobicity of TiO 2 NPs. Our study demonstrated the close relationship between surface properties of TiO 2 NPs and their biological effects, providing important evidence for understanding the behavior of nanomaterials in aquatic environments.
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 2
·1-11
·
IF 5.3
Zhang Xiaoyu,Sun Ruimeng,Zheng Haoran,Qi Yanfei
A spherical nucleic acid (SNA, AuNPs-aptamer) into CRISPR/Cas12a system combined with poly T-template copper nanoparticles as fluorescence reporter was fabricated to establish an amplification-free sensitive method for Staphylococcus aureus ( S. aureus ) detection. This method, named PTCas12a, utilizes the concept that the bifunction of SNA recognizes the S. aureus and triggers the Cas12a cleavage activity. Then, the Cas12a enzyme cleaves the Poly T40 to generate a signal change in Poly T-Cu fluorescence, indicating the presence or absence of the target bacteria. The PTCas12a platform demonstrated a detection limit as low as 3.0 CFU/mL (3 N/S) in a wide response range of 1.0 × 10 1 –1.0 × 10 6 CFU/mL for S. aureus detection, which holds significant potential in ensuring food safety and preventing the spread of diseases. Graphical abstract
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Siying Pei,Wenhui Ji,Ya Yang,Shuo Yang,Tianwei Liu,Jiangxuan Dai,Chan Fu,Jiayi Wu,Yu Yin,Qiong Wu,Bing Zheng,Lin Li
Wearable sweat sensors have made significant progress in the field of human health monitoring, with the ability to achieve continuous collection, monitoring, and transmission of sweat. Current wearable sweat sensors are predominantly enzyme-based, which presents limitations such as high cost, inadequate long-term stability, and vulnerability to environmental conditions. In this study, we present a printed enzyme-free wearable potentiometric sensor for monitoring sweat lactate. Specific and highly sensitive electrocatalysis of sweat lactate was achieved by constructing composite nanomimetic enzyme materials, which involved modifying a screen-printed working electrode with multi-walled carbon nanotubes (MWCNTs) and copper metal-organic framework materials ( Cu-HHTP ). The conversion of divalent copper ions (Cu 2+ ) in Cu-HHTP to monovalent copper ions (Cu + ) in the presence of sodium chloride (NaCl) led to the rapid electrocatalytic oxidation of lactate into pyruvate. The incorporation of MWCNTs enhanced the conductivity and electron transport efficiency of Cu-HHTP , thereby improving the sensitivity. The sensor exhibited an exceptionally low detection limit (1.09 μM), remarkably high sensitivity in the ranges of 1–10 mM (118.55 mV/decade) and 10–50 mM (47.98 mV/decade), as well as outstanding selectivity, reproducibility, and stability. Finally, the developed wearable potentiometric sensor continuously and dynamically monitored changes in sweat lactate levels during physical exercise. This study presents a novel enzyme-free method for the detection of sweat lactate, which holds promise as a valuable support for personalized health diagnosis.
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