JOURNAL OF ALLOYS AND COMPOUNDS
·
2018
·
IF 3.779
Mingye Ding,Chunhua Lu,Le Chen,Zhenguo Ji
Traditional FIR (fluorescence intensity ratio)-based optical thermometers, requiring narrow energy gap between two thermally coupled states (TCS) of single rare-earth ion, have inherent drawbacks including low signal discriminability and large measuring error. To overcome the intrinsic limitation, a new thermometry strategy involving the usage of dual-emitting activators with diverse temperature-dependent emission behaviours has been proposed. Impressively, β-NaYF 4 :Ce 3+ /Tb 3+ phosphor exhibits good temperature sensing performance, excellent signal discriminability and superior thermal stability by using the linearly temperature-dependent FIR between Ce 3+ and Tb 3+ as detecting parameter. Hopefully, the developed dual-emitting sample could have a promising application in self-calibrated luminescent thermometry and this strategy provides a reference for developing high-performance optical thermometers.
研究领域:
材料科学
·
光学工程
·
无机化学
·
生物医学工程
·
纳米技术
·
传感器
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2020
·
IF 5.162
Zhong Shi,Zhuangzhuang Shi,Mengmeng Wu,Yaqi Shen,Guoqiang Li,Ting Ma
Food-grade emulsion gels have attracted increasing attention in food and drug manufacturing, owing to their potential as novel delivery systems for lipophilic bioactive ingredients. Emulsion gels are structurally either a polymeric gel matrix with incorporated emulsion droplets (emulsion-filled gels), or a network of aggregated emulsion droplets (emulsion particulate gels). In this study, a novel emulsion gel was prepared by formulating an oil-in-water (O/W) emulsion stabilized by sanxan alone, followed by heating and cooling treatment, resulting in a structured solid system. Stable O/W type sanxan emulsion gels (SEGs) were obtained at sanxan concentration >0.5% ( w /w). Fluorescence microscopy results confirmed the adsorption of sanxan on oil droplet surfaces. The effect of temperature and sanxan/oil concentrations on the rheological and textural properties of the SEGs was evaluated: the SEG containing 1% (w/w) sanxan and 20% (w/w) sunflower oil exhibited excellent rheological and textural properties. Further, the addition of 10 mM Na + or 5 mM Ca 2+ greatly enhanced the thermostability of the SEG. The potential of SEGs as sustained-release delivery systems for β-carotene was also explored. The findings are of great interest for the development of novel delivery systems based on emulsion gels stabilized by sanxan for the sustained release of lipophilic components.
研究领域:
食品科学
·
药物制剂
✓ 已验证
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2017
·
IF 4.811
Yezhou Jiang,Bingchuan Liu,Jikun Xu,Keliang Pan,Huijie Hou,Jingping Hu,Jiakuan Yang
A complex chitosan/β-cyclodextrin polymer was synthesized by bridging with maleoyl chains followed by cross-linking with glutaraldehyde. The adsorption performance of the synthetic polymer was investigated for selective removal of methyl orange (MO) from aqueous solution. The kinetic behavior was well fitted by the pseudo-second order model, while the adsorption process at equilibrium followed the Langmuir isotherm model. The thermodynamic parameters suggested that the adsorption was exothermic and spontaneous. Under optimal adsorption conditions, the capacity for MO reached 392 mg/g with the dosage of 10 mg/50 mL. Based on the analysis from FTIR, 1 H NMR, TGA and zeta potential, the adsorption mechanism could be explained by the synergistic effect of electrostatic attraction of amino groups from chitosan and host-guest interaction from β-cyclodextrin. This adsorbent also demonstrated high selectivity towards MO due to the unique structure of cross-linked chitosan/β-cyclodextrin polymer that are complementary to that of MO molecule.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
NANOTECHNOLOGY
·
2019
·Vol. 30
·期 18
·185502
·
IF 3.399
Yu Xie,Xiaolong Tu,Xue Ma,Qingwen Fang,Limin Lu,Yongfang Yu,Guangbin Liu,Changxiang Liu
2, 2-methylenebis (4-chlorophenol) (dichlorophenol, Dcp) is a priority pollutant that poses a serious health threat to the public. Thus, the sensitive analysis of Dcp is of great significance. Heteroatom-doped carbon nanomaterials modified electrodes have been proven to be good electrocatalysts for electrochemical sensing application. β-cyclodextrin (β-CD) as a signal amplifier has also been utilized in biosensors. Inspired by these, in this study, a new composite of β-CD and three-dimensional (3D) boron-doped graphene aerogels (BGAs/β-CD) has been designed as a high-performance electrochemical sensing platform for Dcp determination. Graphene aerogels possess high specific surface area, large pore volume and good conductivity, which ensure rapid mass transfer and accelerated electron transfer. Besides, boron doping causes uneven charge distribution on the graphene lattice surface, producing a large amount of flowing π electrons, which provide abundant active sites for the catalytic oxidation reaction of Dcp. In addition, Dcp molecules could be captured into β-CD through host-guest recognition, which can effectively amplify the detection signal. Combining the merits of BGAs and β-CD, the BGAs/β-CD based sensor achieved sensitive detection of Dcp. Under optimized experimental conditions, the oxidation currents and the concentration of Dcp had a good linear relationship within 1.0 nM ∼ 21 μM. The detection limit was estimated as 0.33 nM (S/N = 3). This study might provide a new basis for the fabrication of 3D BG-based aerogel architectural material and its application in Dcp detection.
研究领域:
环境科学
·
分析化学
✓ 已验证
DOI
高影响因子
ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE
·
2022
·Vol. 649
·期 4
·e202200279
·
IF 1.414
Shuai-Cong Huo,Yao Li,Peng-Fei Ji,De-Xiang Zhang,Zhi-Jiao Zhang,Ying Yang,Herbert W. Roesky
Treatments of β -diketiminate aluminum dihydride LAlH 2 (L=HC[C(Me)N(Ar)] 2 , Ar=2,6- i Pr 2 C 6 H 3 ) with (2-chlorophenyl)methanol, 2,3-dimethylbutane-2,3-diol, 2,2-dimethylpropane-1,3-diol, 2,2-bis(bromomethyl)propane-1,3-diol, and p -diphenol resulted in the formation of compounds containing the C−O−Al−O−C linkages, including the acyclic LAl[( μ -O)CH 2 ( o -Cl−C 6 H 4 ) 2 ] 2 ( 1 ), the five-membered ring LAl[( μ -O)CMe 2 ] 2 ( 2 ), the six-membered ring LAl[( μ -O)CH 2 ] 2 CMe 2 ( 3 ) and LAl[( μ -O)CH 2 ] 2 C(CH 2 Br) 2 ( 4 ), and the macrocyclic [LAl( μ -O) 2 ( p -C 6 H 4 )] 4 ( 5 ), respectively. These practices prove that β -diketiminate aluminum dihydride is a valuable precursor for the preparation of acyclic and cyclic systems. 1 – 5 were characterized by melting point, 1 H and 13 C NMR, FT-IR, and single-crystal X-ray diffraction studies.
研究领域:
无机化学
·
材料化学
✓ 已验证
DOI
高影响因子
Small
·
2012
·Vol. 9
·期 3
·446-456
·
IF 8.349
Haiqing Dong,Yongyong Li,Jinhai Yu,Yanyan Song,Xiaojun Cai,Jiaqiang Liu,Jiaming Zhang,Rodney C. Ewing,Donglu Shi
A multi-component nanosystem based on graphene and comprising individual cyclodextrins at its surface is assembled, creating hybrid structures enabling new and important functionalities: optical imaging, drug storage, and cell targeting for medical diagnosis and treatment. These nanohybrids are part of a universal system of interchangeable units, capable of mutilple functionalities. The surface components, made of individual β-cyclodextrin molecules, are the “hosts” for functional units, which may be used as imaging agents, for anti-cancer drug delivery, and as tumor-specific ligands. Specifically, individual β-cyclodextrin (β-CD), with a known capability to host various molecules, is considered a module unit that is assembled onto graphene nanosheet (GNS). The cyclodextrin-functionalized graphene nanosheet (GNS/β-CD) enables “host–guest” chemistry between the nanohybrid and functional “payloads”. The structure, composition, and morphology of the graphene nanosheet hybrid have been investigated. The nanohybrid, GNS/β-CD, is highly dispersive in various physiological solutions, reflecting the high biostability of cyclodextrin. Regarding the host capability, the nanohybrid is fully capable of selectively accommodating various biological and functional agents in a controlled fashion, including the antivirus drug amantadine, fluorescent dye [5(6)-carboxyfluorescein], and Arg-Gly-Asp (RGD) peptide-targeting ligands assisted by an adamantine linker. The loading ratio of 5(6)-carboxyfluorescein is as high as 110% with a drug concentration of 0.45 mg mL −1 . The cyclic RGD-functionalized nanohybrid exhibits remarkable targeting for HeLa cells.
研究领域:
生物医学工程
·
材料科学
·
纳米医学
✓ 已验证
DOI
PubMed
高影响因子
PHYTOTHERAPY RESEARCH
·
2011
·Vol. 25
·期 10
·1519-1526
·
IF 1.878
Dong-Yan Shen,Jin-He Kang,Wei Song,Wen-Qing Zhang,Wen-Gang Li,Yan Zhao,Qing-Xi Chen
The study aimed to evaluate the effects of β-escin on human cholangiocarcinoma cell lines (QBC939, Sk-ChA-1 and MZ-ChA-1) and to explore its mechanisms. Cell growth, cell cycle and apoptosis were investigated, respectively, by MTT assay, single PI and FITC/PI double-staining flow cytometry, and fluorescence microscopy. The protein expression was determined by western blotting. The study revealed that β-escin inhibited cholangiocarcinoma cell growth in a dose- and time-dependent manner, and the cell cycle of QBC939 and Sk-ChA-1 cells was arrested in the G2/M phase, and MZ-ChA-1 cells in G1 phase. Apoptosis of the three cholangiocarcinoma cell lines induced by β-escin was associated with the collapse of the mitochondrial membrane potential and the activation of caspase-3. The apoptotic effect of β-escin was suppressed by pancaspase inhibitor z-VAD-fmk. Molecular dissection revealed that the antiapoptotic protein bcl-2 was down-regulated after cholangiocarcinoma cell lines were treated with β-escin, while the protein levels of bax and p53 were unchanged. Apoptosis was accompanied by an increase in reactive oxygen species (ROS). These results suggest that β-escin induces apoptosis of cholangiocarcinoma cells through an intrinsic mitochondrial caspase-dependent pathway, and the increase in the bax/bcl-2 ratio and ROS may play important roles in β-escin-induced apoptosis of cholangiocarcinoma cells. Copyright © 2011 John Wiley & Sons, Ltd.
研究领域:
肿瘤学
·
细胞生物学
·
药理学
✓ 已验证
DOI
PubMed
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2025
·
IF 5.1
Simin Huang,Yizhong Yuan,Huimei Yu,Jinyu Sun,Xiaohui Tian,Chunhua Cai,Yuxuan Han,Yao Zhang
The remediation of wastewater contaminated with heavy metals remains a serious challenge due to the continuing threats posed to ecosystems and human health. While conventional methods such as membrane filtration and flocculation exist, developing sustainable adsorbents with high capacity and reusability is imperative. Therefore, we propose a novel strategy to overcome the limitations of natural polymer-based hydrogels by integrating β-FeOOH nanoparticles into sodium alginate matrices. FTIR, XPS and TG reveal that the incorporation of β-FeOOH not only increases the adsorption active sites but also improves the thermal stability of the composite hydrogels. The composite hydrogel exhibits exceptional adsorption capacity (581.40 mg/g). Crucially, the material maintains over 85 % of its initial efficiency after five adsorption-desorption cycles, demonstrating strong structural integrity and practical applicability. This work provides a mechanistic framework for designing multifunctional hydrogels through nanomaterial hybridization, offering a sustainable pathway for water purification technologies.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
JOURNAL OF ELECTRONIC MATERIALS
·
2023
·Vol. 53
·期 4
·2076-2083
·
IF 2.1
Chen Caifeng,Liu Kai,Zhong Wuwen,Guo Junhao,Tang Xinting,Wang Andong
High β-phase polyvinylidene fluoride (PVDF) thin films have excellent piezoelectricity and flexibility. They are widely used in wearable devices, hydroacoustic ultrasound, and energy harvesting. The preparation of PVDF thin films by near-electric-field 3D printing can be customized in shape, and the high β-phase can be obtained without stretching or polarization. In this work, the effects of polar solvent, printing voltage, and PVDF molecules on the β-phase content of PVDF thin films prepared by near-electric-field 3D printing were analyzed. The results show that the polarity of the solvent affects the molecular chain conformation of PVDF, which is favorable for the generation of the β-phase. With the increase of solvent polarity, the β-phase content in PVDF films increased from 21.40% to 26.31%. The mutual motion of the collecting plate and the needle will produce stronger mechanical traction on the PVDF fibers, which is due to the smaller diameter of the PVDF fibers caused by the high printing voltage. The joint action of this tensile force and the strong electric field attraction promotes the β-phase transition. When the printing voltage is 8 kV, the F (β) value of PVDF film is increased by 47.37% over that without applied voltage. In addition, the interaction of small and large PVDF molecular weight will also result in mechanical deformation of the molecular chain and promote the β-phase transition.
研究领域:
材料科学
·
高分子科学
·
3D打印技术
·
静电学
✓ 已验证
DOI
高影响因子
Frontiers in Bioengineering and Biotechnology
·
2021
·
IF 5.89
He Guangli,Zhou Yue,Li Mifang,Guo Yanzhen,Yin Hang,Yang Baocheng,Zhang Shouren,Liu Yibiao
Amyloid-β protein (Aβ) is an important biomarker and plays a key role in the early stage of Alzheimer’s disease (AD). Here, an ultrasensitive photoelectrochemical (PEC) sensor based on ZnO@polydopamine/Au nanocomposites was constructed for quantitative detection of Aβ. In this sensing system, the ZnO nanorod array decorated with PDA films and gold nanoparticles (Au NPs) have excellent visible-light activity. The PDA film was used as a sensitizer for charge separation, and it also was used for antibody binding. Moreover, Au NPs were loaded on the surface of PDA film by in situ deposition, which further improved the charge transfer efficiency and the PEC activity in visible light due to the localized surface plasmon resonance effect of Au NPs. Therefore, in ZnO@polydopamine/Au nanocomposites, a significantly enhanced photocurrent response was obtained on this photoelectrode, which provides a good and reliable signal for early detection of AD. Under the optimized conditions, the PEC immunosensor displayed a wide linear range from 1 pg/mL to 100 ng/mL and a low detection limit of 0.26 pg/mL. In addition, this PEC immunosensor also presented good selectivity, stability, and reproducibility. This work may provide a promising point-of-care testing method toward advanced PEC immunoassays for AD biomarkers.
研究领域:
生物医学
·
材料科学
·
免疫检测
✓ 已验证
DOI
高影响因子
BEHAVIORAL ECOLOGY AND SOCIOBIOLOGY
·
2022
·Vol. 76
·期 12
·1-10
·
IF 2.944
Li Chengzhe,Wang Hua,Chen Xiaoming,Yao Jun,Deng Jianyu
Abstract Butterflies use visual and olfactory cues to identify conspecifics during courtship. Tirumala limniace , Idea leuconoe , and Danaus chrysippus are three species of butterflies with a sympatric distribution, and T. limniace butterflies are rarely seen to chase I. leuconoe or D. chrysippus during courtship in artificial cultivation gardens, indicating that they have a mechanism for recognizing conspecifics; however, there are no reports on what kind of signals they use to recognize conspecifics. In this study, we investigated the cues used by T. limniace to identify conspecifics and the relative roles of visual and olfactory cues. We found that in the absence of olfactory cues (visual cues only), male and female butterflies were able to identify the same species based on wing color and pattern. By collecting and identifying body volatiles emitted from T. limniace males and females, we found that the highest amounts were β -ocimene and β -pinene, which were sourced from the insects’ bodies (as opposed to sex pheromones). Furthermore, electroantennogram binding behavioral experiments showed that β -ocimene was involved in the process of species recognition and that the relative roles of olfactory cues were greater than those of visual cues at close range. Therefore, T. limniace males and females could utilize both visual and olfactory cues to identify conspecifics during courtship but preferred olfactory cues. The present study highlighted the important role of adult body odor rather than sex pheromones in butterfly species recognition. Significance statement Butterflies use visual (wing color and pattern) and olfactory (sex pheromones) cues to identify conspecifics during courtship. Butterflies also release volatiles emitted from their bodies during courtship. However, there is no clear evidence that body volatiles (as opposed to sex pheromones) emitted from butterflies are involved in species recognition. We studied the functions of body volatiles emitted from Tirumala limniace adults and the relative roles of visual and olfactory cues in species recognition during courtship. We found that male and female adults could identify conspecifics using only visual cues. Meanwhile, we also found that the highest amounts of β -ocimene, which came from the bodies of T. limniace males and females, were also involved in the process of species recognition. The olfactory cues that butterflies use to identify conspecifics are usually sex pheromones, while the present study highlighted the important role of adult body odor rather than sex pheromones in butterfly species recognition.
研究领域:
昆虫学
·
生态学
✓ 已验证
DOI
高影响因子
FOOD AND CHEMICAL TOXICOLOGY
·
2025
·
IF 3.5
Yongjun Tang,Zhengning Feng,Chenlu Ma,Nian Jang,Xiaolong Chen,Yingxu He,Francis L. Martin,Hui Liu,Weiyi Pang
Breast cancer has a high global incidence, and benzo[ a ]pyrene (B[ a ]P) is considered a contributing factor that increases carcinogenic risk. This study examined B[ a ]P's oncogenic mechanisms in mammary epithelial cells. Chronic B[ a ]P exposure induced morphological changes and enhanced proliferative/clonogenic capacity in MCF-10A cells. Chronic B[ a ]P exposure altered gene expression in MCF-10A cells, revealing differential levels of circRNAs, lncRNAs, miRNAs, and mRNAs. qRT-PCR validation demonstrated strong alignment with RNA-seq results, ensuring sequencing reliability. Additionally, chronic B[ a ]P exposure upregulated the protein expression of AhR and ARNT, as well as TGF- β , pSmad2/3, and KRT14 , while increasing Vimentin expression and decreasing E-cadherin expression. Notably, treatment with the TGF- β inhibitor SB431542 reversed these protein expression changes in transformed cells. These results show that exposure to Chronic B[ a ]P induces MCF-10A cell transformation. The underlying mechanisms involve significant transcriptional alterations, AhR/ARNT expression regulation, TGF- β signaling pathway activation, KRT14 protein modulation, and EMT. Furthermore, Chronic B[ a ]P exposure may drive transformation through TGF- β modulation. Chronic B[ a ]P exposure promotes breast carcinogenesis, revealing mechanistic insights and potential preventive biomarkers.
研究领域:
肿瘤学
·
分子生物学
·
细胞生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）