ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Xiangyu Han,Jiaqi Wang,Yongguang Liu,Lei Dai,Ling Wang,Shan Liu
All-solid-state sodium-ion batteries (ASSIBs) with inorganic solid electrolytes can achieve high safety and high energy density when paired with a high-voltage cathode. However, the slow charge transfer and chemical instability between the high-voltage cathode and rigid electrolyte seriously restrict its development. Herein, a high energy density Na4MnCr(PO4)3-based ASSIBs have been achieved by using a simple low-temperature brazing strategy. The in situ generated secondary phase can not only achieve close contact and rapid charge transfer between the Na4MnCr(PO4)3 cathode and electrolyte but also change the interface electric field distribution and reduce interface side reactions effectively. This strategy is simple and easy to implement and has important guidance for the development of other high-energy all-solid-state batteries.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ChemSusChem
·
2022
·Vol. 15
·期 19
·e202201121
·
IF 9.14
Dong Yan,Shuhao Xiao,Xinyan Li,Rui Wu,Jinxia Jiang,Xiaobin Niu,Jun Song Chen
Graphical Balancing act : Boron-doped Na 3 V 2 (PO 4 ) 3 is synthesized through a facile electrospinning method. NVP@carbon with a balanced content of BCO 2 and BC 2 O exhibits the best sodium storage properties. BC 2 O mainly improves the sodium diffusion and BCO 2 enhances the structural stability. Na 3 V 2 (PO 4 ) 3 (NVP) is a widely studied cathode material for sodium-ion batteries because of its high ionic conductivity and attractive charge/discharge plateau (3.4 V vs. Na/Na + ). However, its poor electronic conductivity and severe volume expansion during sodium storage need to be addressed before its intensive application could be realized. Herein, boron-doped NVP was synthesized through a facile electrospinning method. By adding boric acid into the reaction mixture during electrospinning followed by carbonization, boron could be directly inserted into the carbon matrix, giving rise to B-doped carbon nanofiber wrapped NVP. By tuning the doping amount, the boron-containing configurations could be facilely manipulated, playing different roles in promoting the sodium storage properties of the composite. Based on the calculation results, BC 2 O enhanced sodium diffusion by lowering the energy barrier, while BCO 2 improved the structural stability. Due to these specific functionalities of the configurations, the as-prepared composite with a balanced amount of BC 2 O and BCO 2 demonstrated superior sodium storage capacity of 113 mAh g −1 at 1 C, outstanding long cycling performance of 103 mAh g −1 at 10 C, and retained 91 mAh g −1 after 1500 cycles. This gave rise to a capacity loss of only 0.08‰ per cycle, much better than the undoped counterpart.
研究领域:
材料科学
·
能量存储
·
纳米技术
·
电化学
✓ 已验证
DOI
PubMed
高影响因子
GREEN CHEMISTRY
·
2015
·Vol. 17
·期 5
·2888-2895
·
IF 8.02
Jian-hua Guo,Guang-yue Xu,Fei Shen,Yao Fu,Ying Zhang,Qing-xiang Guo
The long-chain alkanes obtained from the hydrodeoxygenation of plant oils are ideal substitutes for diesel. In this work, a new efficient catalytic system was established for the conversion of plant oil to long-chain alkanes under mild conditions with a bi-functional Ru/La(OH)3 catalyst. The hydrodeoxygenation of stearic acid was performed in an autoclave with Ru-based catalysts with different supports (HZSM-5, ZSM-5, SiO2–Al2O3, SiO2, ZrO2, Mg(OH)2, La(OH)3, and La2O3). Among these catalysts, Ru supported on basic La(OH)3 showed a remarkable catalytic performance for the reaction. Over 98% of long-chain alkanes were obtained with 100% conversion of stearic acid at 200 °C and 4 MPa H2. When crude Jatropha oil was hydrogenated, about 80.7 wt% of long chain alkanes were obtained under the optimized conditions (200 °C, 4 MPa H2, 8 h). The high efficiency of the Ru/La(OH)3 catalyst could be due to a co-effect of the high hydrogenation activity of Ru and the basic La(OH)3 support which can attract the acidic raw material. Additionally, the Ru/La(OH)3 catalyst was recycled four times and maintained a good activity and stability. The reaction pathway was also explored by using stearic acid as a model compound. Hydrogenation–decarbonylation could be the main pathway to produce n-heptadecane, which has one carbon atom less than stearic acid.
研究领域:
化学工程
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催化
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可再生能源
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生物燃料
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2018
·
IF 8.097
Peng Wei,Yanxiang Liu,Yarui Su,Ling Miao,Yangyang Huang,Yi Liu,Yuegang Qiu,Yuyu Li,Xiaoyu Zhang,Yue Xu,Xueping Sun,Chun Fang,Qing Li,Jiantao Han,Yunhui Huang
We are presenting a sol–gel method for building novel nanostructures made of nanosized F-doped Na1–2xTi2(PO4)3–xFx (NTP-Fx, x = 0, 0.02, 0.05, and 0.10) particles embedded in three-dimensional (3D) carbon matrices (NTP-Fx/C). This technique combines advantages of both zero-dimensional materials and 3D-carbon networks. Proper fluorine doping stabilizes the NTP structure and greatly enhances ion/electron transportation, leading to superhigh-rate electrochemical performance and ultralong cycle life. The composite electrode delivers high specific capacities of 121, 115, 112.2, 110.1, 107.7, 103.1, 85.8, and 62.5 mA h g–1 at 0.2, 0.5, 1, 2, 5, 10, 20, and 30 C, respectively. It retains an unbelievable ∼70% capacity after a thousand cycles at a rate as high as 10 C. Electroanalytical results reveal that fluorine doping significantly enhances Na+ diffusion kinetics. Meanwhile, density functional theory calculations demonstrate F-doped NTPs’ own outstanding electrochemical properties, which is due to the enhanced intrinsic ionic/electronic conductivity. The results show that anion doping is an efficient way to make high-performance NTP anodes for sodium-ion batteries.
研究领域:
电化学
·
材料科学
·
能源存储
·
纳米材料
·
固态化学
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电化学储能
✓ 已验证
DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2025
·
IF 6.2
Bin Ma,Jiafeng Niu,Hao Zhu,Huibing Chi,Zhaoxin Lu,Fengxia Lu,Ping Zhu
Aldo-keto reductase is responsible for the formation of nontoxic 3-epi-deoxynivalenol (3-epi-DON) from 3-keto-DON, which is an enzymatic detoxification manner to completely eliminate the toxicity of mycotoxin DON against health and environmental threats. Therefore, unlocking the facilitated substrate specificity of aldo-keto reductase for 3-keto-DON has become a critical challenge for advanced catalytic performance. In this endeavor, a loop-based engineering strategy was developed for aldo-keto reductase AKR13B3 from Devosia A6–243 to catalyze 3-keto-DON. A 31.9-fold switch from a disfavored substrate to the preferred one was produced along with a significant 37.9-fold increase in catalytic efficiency. Kinetic parameter determinations, structural analyses, and molecular simulations were employed to elucidate the molecular mechanisms underlying these enhancements in catalytic activity and substrate specificity. Overall, our work presents a feasible scheme for designing aldo-keto reductases with exceptional substrate specificity and catalytic activity, holding great promise for developing enzymatic detoxification agents.
研究领域:
生物化学
·
分子生物学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Sustainable Energy & Fuels
·
2025
·
IF 4.1
Yitao Hui,Xianhe Meng,Aobo Yue,Qi Shen,Bingyu Liu,Nengjun Yu,Qiaoling Kang,Lijing Yan,Chubin Wan,Tingli Ma
Na superionic conductors (NASICONs) have attracted much attention due to their unique framework structure and high capacity. However, the poor intrinsic electron conductivity severely limits further development. This work develops a soft-hard carbon composite modified Na3V2(PO4)3 (NVP) cathode with excellent rate performance and long-term cycling stability. The optimized sample exhibits excellent electrochemical performance and can release a specific discharge capacity of 102.7 mAh g-1 at 1 C rate. At the same time, after 5000 cycles at 20 C rate, the discharge capacity can reach 82.3 mAh g-1, and the capacity retention rate is 100.1 %. The morphological characteristics of the NVP/C samples were investigated, Meanwhile, combined with Raman spectroscopy and electrochemical analysis, these results revealed that the synergistic interaction between soft and hard carbon components significantly enhances electronic conductivity and facilitates rapid ionic transport. This work provides a unique idea for the surface modification and synthesis of NASICON cathode materials for sodium-ion batteries.
研究领域:
材料科学
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电化学
·
能源存储
·
无机固体化学
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纳米材料
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电池技术
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry B
·
2024
·
IF 6.1
Gong Chen,Yuan Yuan,Ying Li,Zushun Xu,Qianyuan He,Zizhen Qin,Han Hu,Congcong Gao,Qi Xu,Qinglei Gao,Fei Li
Oncolytic virus ablation of tumor cells has the advantages of high tumor selectivity, strong immunogenicity and low side effects. However, the recognition and clearance of oncolytic viruses by the immune system is the main reason that limits their anti-tumor efficiency. As a highly biosafe and highly modifiable oncolytic virus vector, acrylamide can improve the long-term circulation of oncolytic viruses, but it is limited in its uptake efficiency by tumor cells. Herein, we constructed a N- hydroxymethyl acrylamide -b-(N-3- aminopropyl methacrylamide) -b-DMC block copolymers (NMA-b-APMA-b-DMA, NAD) as an oncolytic virus carrier, which not only improves the long-term circulation of oncolytic viruses in the body but also has excellent loading oncolytic virus stability. The data shows that no obvious difference in the transfection effect of the NAD/Ad complex with or without neutralizing antibody in the medium, which meant that the cationic carrier mediated by NAD/Ad had good serum stability. Only 10 micrograms of NAD carrier are needed to load the oncolytic virus, which can increase the transfection efficiency by 50 times. Cell experiments and mouse animal experiments show that NAD vector can significantly enhance the anti-tumor effect of oncolytic viruses. We hope that this work will promote the application of acrylamide as an oncolytic virus vector and provide new ideas for modification methods of acrylamide for biomedical applications.
研究领域:
生物医学
·
肿瘤学
·
病毒学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
POSTHARVEST BIOLOGY AND TECHNOLOGY
·
2024
·
IF 6.4
Ruiling Zhuo,Xiaokang Zhang,Yong Chen,Mengyang Xing,Shiping Tian,Boqiang Li
Penicillium expansum , a causal agent of blue mold rot, leads to substantial postharvest losses in the fruit industry. Due to environmental pollution and the emergence of fungicide-resistant strains, the use of synthetic chemical fungicides faces severe challenges. Natural antifungal compounds derived from plants are considered promising alternatives. In this study, the antifungal activities of coumarin and five hydroxylated derivatives against P. expansum and involved mechanisms were investigated. Among the six coumarins, 3-hydroxycoumarin (3-HC) demonstrated strong inhibitory effects on mycelial growth, germ tube elongation, conidiation, patulin production, and the best control effect on blue mold in apple and jujube fruit. Moreover, 3-HC increased the sensitivity of P. expansum to the cell wall, oxidative, and osmotic stresses . In silico analyses, including target fishing, molecular docking, and molecular dynamics simulations, revealed that the mitogen-activated protein kinase (MAPK) family in P. expansum (Pempks), were the potential targets of 3-HC. Bio-layer interferometry and ATP competition assays found that 3-HC could directly bind to PempkB and PempkC , and inhibit the MAPK activity. Our results suggested that 3-HC may act as an ATP-competitive MAPK inhibitor to affect the MAPK signaling pathway and inhibit the development and pathogenicity of P. expansum .
研究领域:
植物病理学
·
分子生物学
·
植物化学
✓ 已验证
产品关联
DOI
高影响因子
Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy
·
2024
·
IF 1.4
Xie Huilong,Fu Yunrong,Lin Zhisheng,Wang Jiayi,Wu Jingyu,You Xiuhua,Xie Jieming
This study explores the synergistic effect of T-CUS 245C combined with cyclosporin A, and its possible mechanism. T-CUS 245C is an immunotoxin conjugated with tastuzumab and recombinant cucurmosin 245C (CUS 245C ). Cyclosporin A is a calcium antagonist mainly used as an immune-suppressive agent, which enhances the cytotoxicity of immunotoxins through an unknown mechanism. The sulforhodamine B assay, flow cytometry, DNA fragmentation apoptosis assay, and western blot analysis were used to evaluate the synergistic effects of cyclosporin A combined with T-CUS 245C on proliferation inhibition and apoptosis induction in SK-OV-3 ovarian cancer cells with HER-2-overexpressing. Meanwhile, using confocal microscopy and flow cytometry, the effect of cyclosporin A on the intracellular distribution of T-CUS 245C was observed and quantified. The results of this study showed that the combination index of cyclosporin A combined with T-CUS 245C is less than 0.7, indicating that cyclosporin A significantly enhances the proliferation inhibition and apoptosis induction induced by T-CUS 245C in SK-OV-3 cells. The confocal microscopy and flow cytometry results show that cyclosporin A effectively increases the dispersion of T-CUS 245C in the cytoplasm by promoting the endolysosomal escape. This study demonstrates that cyclosporin A combined with T-CUS 245C has a synergistic anticancer effect, by facilitating the release of T-CUS 245C in the intracellular space. Graphical Abstract
研究领域:
肿瘤学
·
细胞生物学
·
药理学
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Lichen Zhang,Xing Su,Shuo Wang,Xiaodong Li,Meishuai Zou
Fluoride coating can reduce the ignition temperature, enhance the burning rate and inhibit the agglomeration of aluminum powder. However, the addition of non-energetic fluoride can reduce the energy of aluminum powder. In this study, for the first time, 3-Perfluorohexyl-1,2-epoxypropane (PFHP) was coated on the surface of aluminum powder, which reacted with glycidyl azide polymer (GAP) in situ to form core–shell Al@PFHP@GAP. Compared with raw aluminum powder, Al@PFHP@GAP not only significantly reduced ignition temperature (about 150 °C), but also greatly improved the combustion efficiency (from 87.7% to 97.6%). Besides, the heat of combustion was also greatly increased by 6.3%, compared with that of raw aluminum powder. Such performances were outstanding among the existing coated Al. In addition, the formation of coating shell effectively improved the hydrophobicity and corrosion resistance of the aluminum powder. In a word, our derived Al@PFHP@GAP provided a novel rationale for aluminum powder with greatly enhanced combustion performance.
研究领域:
材料科学
·
高能材料
✓ 已验证
DOI
高影响因子
SOLAR ENERGY
·
2024
·
IF 6
Zhi-Ping Huang,Hui-Li,Wei-Ze Wang,Hu Li,Li-Mei Lin,Zhi-Gao Huang,Shui-Yuan Chen,Gui-Lin Chen
Sb 2 (S,Se) 3 is a promising photovoltaic material due to its tunable bandgap, high thermal stability, and low-cost production potential. However, films produced by close-spaced sublimation (CSS) often suffer from defects that reduce efficiency. In this work, lithium (Li) doping was introduced to improve crystal quality, carrier concentration, and conductivity. The lithium was incorporated into the sublimation source via molten salt treatment, resulting in a uniform Li-Sb 2 (S,Se) 3 thin film. The resulting ITO/CdS/Li-Sb 2 (S,Se) 3 /PbS/Carbon solar cell achieved a power conversion efficiency of 6.18%, a significant improvement over undoped devices. The study further investigates the optoelectronic properties, revealing that Li doping effectively reduces non-radiative recombination, improves carrier extraction, and increases the valence band maximum (VBM), optimizing energy level alignment for enhanced hole transport. Additionally, the improved surface conductivity and higher carrier concentration due to Li doping contributed to enhanced carrier transport and reduced recombination.This research demonstrates that alkali metal doping can enhance the optoelectronic properties of Sb 2 (S,Se) 3 films, providing a pathway for further efficiency improvements in antimony-based thin-film solar cells.
研究领域:
材料科学
·
光伏技术
·
半导体物理
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
·
2017
·
IF 2.603
Yang Xu,Dongwen Hu,Yuting Li,Chongde Sun,Wei Chen
Accumulating evidence indicates that consumption of berries may exert beneficial effects against oxidative stress mediated diseases. Pelargonidin -3-O- glucoside (Pg3G), a bioactive ingredient in strawberry, has been reported to possess a potent antioxidant capacity. This study was therefore designed to develop an effective method to prepare pure Pg3G from strawberry and investigate its protective effect against H 2 O 2 -induced oxidative stress. According to our results, Pg3G occupied 85.55% of total anthocyanin content in strawberry. 240 mg of Pg3G with the purity of 97.26% was finally isolated from 320 g of strawberry lyophilized powder (SLP) by combination of AB-8 macroporous resin and high-speed counter-current chromatography (HSCCC) technologies. Further study unveiled that Pg3G significantly inhibited H 2 O 2 -induced ROS generation, GSH depletion and mitochondrial dysfunction, thereby ameliorating H 2 O 2 -induced oxidative stress. Overall, this study suggests that pelargonidin -3-O- glucoside can be used as a natural bioactive agent to prevent cellular oxidative stress.
研究领域:
食品科学
·
生物化学
·
药理学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）