WATER RESEARCH
·
2021
·
IF 11.236
Qianyuan Yang,Longqian Xu,Qunbiao He,Deli Wu
Electrochemical precipitation is a promising technique for hardness abatement without the addition of external ions. However, the scale layer on cathode deteriorated the removal efficiency and limited the practical application. Herein, a fenced cathode structure was designed to prevent cathodic precipitation. The cathode was fenced by a crystallization-inducing material for separating the OH − production and crystallization processes. Precipitation on the cathode was confirmed to shift to the crystallization-inducing material, and the clean fenced cathode provided efficient long-term OH − production. At a current density of 40 A/m 2 , the Ca 2+ or Mg 2+ removal efficiency increased by 12.8% or 46.1%, respectively, compared to those of a traditional cathode. Thermodynamic equilibrium in synthetic water and mine water, mass transfer and the location of precipitation were analyzed to elucidate the electrochemical precipitation process. The enhanced mechanism was ascribed to the crystallization-inducing material, which remarkably promoted the crystallization process, and hindered OH − migration, thereby increased the pH of alkaline microenvironment. Notably, a recovery design was proposed to recover pure calcite and brucite from alkalinity-free wastewater. The design reveals a promising strategy for enhancing the crystallization process and reducing cathodic scale, also initiating a new research direction toward hardness removal.
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ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
·
2017
·Vol. 40
·期 5
·1979-1986
·
IF 2.616
Zhang Tianyu,Wang Tao,Lu Yujuan
The bioavailability and toxicity of zinc to aquatic life depend on dissolved organic matter (DOM), such as Suwannee River Fulvic Acid (SRFA), which plays an important role in the speciation of zinc. This study examined reactions of SRFA with zinc at different concentrations from pH 3.0 to 9.0, and competitive binding of calcium/magnesium and zinc to SRFA at pH 6.0, using in situ absorbance. Interactions of Zn 2+ with SRFA chromophores were evidenced by the emergence of features in Zn-differential spectra. Among all Zn 2+ –SRFA systems, dominant peaks, located at 235, 275 and 385 nm, and the highest intensity at 235 nm indicated the replacement of protons by the bound Zn 2+ . The Zn 2+ binding with SRFA could be quantified by calculating the changes of the slopes of Zn-differential log-transformed absorbance in the wavelength range of 350–400 nm (denoted as DS 350–400 ) and by comparing the experimental data with predictions using the Non-Ideal Competitive Adsorption (NICA–Donnan) model. DS 350–400 was correlated well with the bound Zn 2+ concentrations predicted by NICA–Donnan model with or without Ca 2+ or Mg 2+ . Ca 2+ and Mg 2+ only affect intensity of the Zn-differential and Zn-differential log-transformed absorbance, not shape. In situ absorbance can be used to gain further information about Me n+ –DOM interactions in the presence of various metals.
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CHEMISTRY-A EUROPEAN JOURNAL
·
2018
·Vol. 24
·期 24
·6458-6463
·
IF 5.16
Xinyue Song,Zihong Yue,Jiayu Zhang,Yanxialei Jiang,Zonghua Wang,Shusheng Zhang
Graphical By taking advantage of a lack of spectral overlapping and single NIR excitation wavelengths, sandwich-structured multicolor upconversion nanoparticles (SWUCNPs) were used to establish a dual luminescence resonance energy transfer (LRET) nanoprobe with special recognition ligands. The quenched fluorescence would be recovered after the detachment and/or absorbance change of the attached ligands (see scheme) to investigate the interplaying roles of [Ca 2+ ] i and pH i . Intracellular [Ca 2+ ] i and pH i have a close relationship, and their abnormal levels can result in cell dysfunction and accompanying diseases. Thus, simultaneous determination of [Ca 2+ ] i and pH i can more accurately investigate complex biological processes in an integrated platform. Herein, multicolor upconversion nanoparticles (UCNPs) were prepared with the advantages of no spectral overlapping, single NIR excitation wavelengths, and greater tissue penetration depth. The upconversion nanoprobes were easily prepared by the attachment of two fluorescent dyes, Fluo-4 and SNARF-4F. Based on the dual luminescence resonance energy transfer (LRET) process, the blue and green fluorescence of the UCNPs were specially quenched and selectively recovered after the detachment and/or absorbance change of the attached fluorescent dyes, enabling dual detection. Importantly, the developed nanoprobe could successfully be applied for the detection of [Ca 2+ ] i and pH i change in adenosine triphosphate (ATP) and ethylene glycol tetraacetic acid (EGTA) stimulation in living cells.
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Journal of Environmental Sciences
·
2023
·
IF 6.9
Ting He,Jie Sun,Liangwei Deng,Jialin Ming,Changwei Hu
Due to its high efficiency, Fe(II)-based catalytic oxidation has been one of the most popular types of technology for treating growing organic pollutants. A lot of chemical Fe sludge along with various refractory pollutants was concomitantly produced, which may cause secondary environmental problems without proper disposal. We here innovatively proposed an effective method of achieving zero Fe sludge, reusing Fe resources (Fe recovery = 100%) and advancing organics removal (final TOC removal > 70%) simultaneously, based on the in situ formation of magnetic Ca-Fe layered double hydroxide (Fe 3 O 4 @CaFe-LDH) nano-material. Cations (Ca 2+ and Fe 3+ ) concentration (≥ 30 mmol/L) and their molar ratio (Ca:Fe ≥ 1.75) were crucial to the success of the method. Extrinsic nano Fe 3 O 4 was designed to be involved in the Fe(II)-catalytic wastewater treatment process, and was modified by oxidation intermediates/products (especially those with COO − structure), which promoted the co-precipitation of Ca 2+ (originated from Ca(OH) 2 added after oxidation process) and by-produced Fe 3+ cations on its surface to in situ generate core-shell Fe 3 O 4 @CaFe-LDH. The oxidation products were further removed during Fe 3 O 4 @CaFe-LDH material formation via intercalation and adsorption. This method was applicable to many kinds of organic wastewater, such as bisphenol A, methyl orange, humics, and biogas slurry. The prepared magnetic and hierarchical CaFe-LDH nanocomposite material showed comparable application performance to the recently reported CaFe-LDHs. This work provides a new strategy for efficiently enhancing the efficiency and economy of Fe(II)-catalyzed oxidative wastewater treatment by producing high value-added LDHs materials.
研究领域:
环境工程
·
废水处理
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材料科学
·
化学工程
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Small
·
2022
·Vol. 18
·期 23
·2201123
·
IF 15.153
Jing Li,Yao Zhang,Zhichao Lou,Mingxi Li,Lin Cui,Zhenrong Yang,Lijuan Zhang,Yu Zhang,Ning Gu,Fang Yang
Neural stem cells (NSCs) are used to treat various nervous system diseases because of their self-renewal ability and multidirectional differentiation potential. However, an insufficient ability to track their migration in vivo and poor control over their survival and differentiation efficiency are two major critical challenges for clinical application. Here, it is shown that when magnetic nanobubbles (MNBs), which are assembled from magnetic nanoparticles, are internalized by NSCs, intramembrane volumetric oscillation of the MNBs induces an increase in intracellular hydrostatic pressure and cytoskeleton force, resulting in the activation of the Piezo1-Ca 2+ mechanosensory channel. This subsequently triggers the BMP2/Smad biochemical signaling pathway, leading to differentiation of NSCs into the neuronal phenotype. Signaling through the Piezo1-Ca 2+ -BMP2/Smad pathway can be further accelerated by application of an external shear stress force using low-intensity pulsed ultrasound. More importantly, magnetic resonance imaging and ultrasound imaging surveillance of NSCs based on MNB labeling can be leveraged to provide NSC therapeutic outcomes. Both the in vitro and in vivo findings demonstrate that a bubble nanostructure-induced physical force can modulate and control the mechanical signaling pathway regulating stem cell development.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Ming Ouyang,Xi Yu,Jiani Zhong,Yan Mao,Yunqian Cui,Huiqin Jiang,Xiaoying Lu,Weiyu Cao,Zeting Yuan,Jingbo Yin
The inflammatory environment of periodontitis with bacteria, excessive reactive oxygen species (ROS) and limited regenerative capacity of alveolar bone makes reconstruction of periodontium become a huge challenge. The present strategies, such as local debridement and antibiotic injection, are difficult to solve above problems completely. Thus, to reverse the progression of the disease, Ca 2+ -tannic acid nanocomposites loaded into injectable sodium alginate/4-arm polyethylene glycol-lipoic acid hydrogel (CaTA@Gel) were fabricated, including Ca 2+ ‑sodium alginate (SA) ionic crosslinking and radical polymerization of lipoic acid-modified 4-arm polyethylene glycol (PEG-SS 4 ) under UV illumination. In our results, the double networks of hydrogel not only had good mechanical property, but also sustainedly released CaTA nanocomposites which could inhibit bacteria, scavenge ROS due to TA, and promote osteogenesis of bone mesenchymal stem cells (BMSCs) via Ca 2+ . The antibacterial rates of CaTA (1 mg/mL) against E. coli and S. aureus were 97.3 ± 1.25 % and 96.7 ± 2.57 %, respectively. Meanwhile, ·OH and ·O 2− could be inhibited obviously by CaTA (100 μg/mL), whose inhibition rate were 59.6 ± 2.98 % and 62.4 ± 3.12 %, respectively. Finally, the up-regulation of osteogenetic genes and successful alveolar bone regeneration in rat models indicated this injectable nanocomposite hydrogel provided a promising strategy for the treatment of periodontitis.
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FOOD HYDROCOLLOIDS
·
2024
·
IF 11
Jipeng Zhang,Xiaojun Zhang,Chongyang Zhu
The self-assembly behavior of proteins and peptides has been widely studied due to their ability to construct various nanostructures, such as nanotubes and nanofibrils. Understanding the self-assembly mechanism is of great significance for developing functional nanomaterials. Herein, we adopt a novel method to construct ovotransferrin (OVT) fibrils by subtilisin A hydrolysis and Ca 2+ ions induced self-assembly with mild reaction conditions. The kinetic process of OVT fibrils formation contains lag, growth, and plateau stage. During the growth stage, OVT peptides self-assemble into precursor structures, which undergo morphological changes of twisted ribbons, helical ribbons, and nanotubes, ultimately closing to form mature fibrils. Ca 2+ ions likely coordinate with the carboxyl groups of OVT peptides, aiding in the self-assembly process. And the secondary conformation is manifested as a β-sheet stacking. The mature OVT fibrils have distinct hollow and left-handed structures. Then OVT fibrils successfully encapsulate zeaxanthin (Zea) and improve its solubility and stability. Besides, OVT fibrils exhibit no in vitro cytotoxicity, and significantly reduce allergenicity to egg allergy patients compared to OVT. OVT fibrils delivery Zea into milk to develop Zea fortified dairy beverage and improve the viscosity of dairy beverage. OVT fibrils show a great potential as nutrient delivery and texture optimization for food application.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Haoyu Yue,Zhijie Shang,Pan Xu,Dongyue Feng,Xinxue Li
A novel EDTA functionalized chitooligosaccharide/sodium alginate/Ca 2+ physical double network hydrogel (ECSDNH) was prepared by using of high-salinity oilfield produced water. The formation and structure of ECSDNH were characterized by FT-IR and SEM. Various factors, including EDTA functionalized chitooligosaccharide content, pH of solution, initial concentration of heavy metal ions, temperature and contact time, were thoroughly investigated to explore their effect on adsorption capacity of ECSDNH. The obtained results showed that ECSDNH had higher adsorption capacity for Zn 2+ , Ni 2+ and Mn 2+ . The maximum adsorption capacities of Zn 2+ , Ni 2+ and Mn 2+ were 160.19 mg/g, 72.67 mg/g and 52.43 mg/g at 298 K, respectively. The pseudo-second-order kinetic model and Langmuir isotherm model fit the experimental data fairly well. The thermodynamic parameters of the adsorption, Δ H ° , Δ S ° , and Δ G ° , were also calculated. In addition, the ECSDNH still had higher removal efficiency for three metal ions after three adsorption-regeneration cycles, indicating its potential application for removing heavy metal ions from wastewater.
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Changhao Wu,Xudong Yu,Nan Zhang,Jing Li,Qi Li,Yousheng Yang,Ke Chen,Bo Yang,Shuang Wang,Yiping Liu,Zhenwen Xing
To solve the massive accumulation of gypsum generated from polyhalite leaching and secondary gypsum, this study investigated phase equilibria of the ternary system NH 4 + , Ca 2+ // SO 4 2- - H 2 O at 323.2 K and 348.2 K. The phase diagrams included 2 invariant points, 3 univariate curves, and 3 crystallization regions corresponding to (NH 4 ) 2 SO 4 , CaSO 4 ·2H 2 O, and double salt koktaite (NH 4 ) 2 Ca(SO 4 ) 2 ·H 2 O. As temperature increased, the crystallization region of CaSO 4 ·2H 2 O contracted, whereas those of (NH 4 ) 2 SO 4 and koktaite expanded, indicating that the temperature-enhanced was beneficial to improve the crystallization efficiency of koktaite. Guided by multitemperature phase diagram, the influencing factors and optimal conditions of the comprehensive utilization process of phosphogypsum were explored. The synthesis of koktaite achieved maximum efficiency under conditions of 1: 1.5 molar ratio, 348.2 K reaction temperature, 90 min duration, and 250 rpm agitation. Concurrently, under solid-liquid ratio of 1: 0.5 and after three leaching cycles of 30 seconds each, the yield of CaSO 4 ·2H 2 O production reached 99.80% with a purity of 99.52%. However, the purity and yield of product decreased due to the accumulation of impurities during the cycles, stabilizing after 6 cycles (koktaite yield: 98.50%; purity: 95.69%; (NH 4 ) 2 SO 4 yield: 97.69%; purity: 95.42%). Granulated koktaite released NH 4 + through layer-by-layer dissolution, which prolonged the dissolution time, and the complete dissolution time was 6 times and 24 times longer than that of ungranulated koktaite and (NH 4 ) 2 SO 4 . This work integrates theoretical phase behavior analysis with process engineering to establish a circular resource recovery strategy for synthesizing high-value products from phosphogypsum.
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SYNTHETIC METALS
·
2014
·
IF 2.222
Fang Liao,Siwei Yang,Xiubing Li,Lijun Yang,Zhihui Xie,Chenshu Hu,Shuai Yan,Tongyan Ren,Zhiduo Liu
Tunable fluorescent nanomaterials are of great significance. In this paper, the poly(o-phenylenediamine) (PoPD) nanospheres were synthesized via chemical oxidation polymerization of o-phenylenediamine (oPD) monomers by (NH 4 ) 2 S 2 O 8 (APS) at room temperature. It is interesting that when this fluorescent nanosphere was doped by F, S and Se via a simple hydrothermal progress, the fluorescence spectrum remarkably changed. The emission peak of F-doped and S-doped PoPD nanosphere was at 411 nm and 530 nm, the spectrum blue shift can be attributed to the electron-withdrawing effect of F and S. On the other side, the emission peak of Se-doped PoPD nanospheres were at 594 nm and can be attributed to the electronic donor effect of Se. These nanomaterials can be used as ultra-sensitive fluorescent detection system (ppb level) for Cu 2+ , Ca 2+ , Hg 2+ and H 2 O 2 . The tunable spectrum and sensing performance of this system is interesting and significant.
研究领域:
材料科学
·
纳米技术
·
分析化学
·
荧光光谱
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Journal of Functional Foods
·
2021
·
IF 4.451
Xiaoyan Su,Ming Zhao,Xinyu Fu,Xiaodan Ma,Wei Xu,Songhua Hu
Polysaccharides from Rubus chingii Hu fruits (RFPs) were extracted, purified, characterized and investigated for immunomodulatory activity. Results indicated that RFPs were heteropolysaccharides with molecular weight of 51.7 kDa and contained carbohydrate contents of 96.83%. RFPs with characteristic absorptive peaks of polysaccharide structure and α-configuration were composed of mannose, rhamnose, glucuronic acid, galacturonic acid, glucose, galactose, arabinose and fucose with a molecular ratio of 0.08:0.17:0.16:0.48:5.73:1.00:1.79:0.03. RFPs promoted splenocyte proliferation, NO release, cytokine production and intracellular Ca 2+ concentration. The mechanism underlying splenocyte activation by RFPs was elucidated by RNA-Seq, in which 2214 differentially expressed genes (DEGs), 2030 GO terms and 92 KEGG pathways were identified. RFPs were further proved to induce a balanced Th1/Th2/Th17 response pattern through MAPK, NF-κB, Jak-STAT and Calcium signaling pathways in splenocytes. These findings provided a fundamental basis for the further application of RFPs as immunomodulators in food and medicine.
研究领域:
免疫学
·
药理学
·
分子生物学
·
生物化学
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CHEMOSPHERE
·
2022
·
IF 8.943
Wenkai Liu,Bin Liu,Xin Li
The aim of this study was to investigate the feasibility and fouling mitigation mechanisms of UV/Fe(II) synergistically activated sulfite (S(IV)) (UFS) pretreatment to alleviate membrane fouling caused by HA-enhanced Ca 2+ scaling. After UFS treatment, hydrophobic substances and carboxyl groups structure were destroyed by the in-situ-generated SO•–4, resulted in a significant reduction of hydrophobic substances ratio and carboxyl group concentration. Due to the formation of more electropositive in-situ-generated Fe(III), the complexation between Ca 2+ and carboxyl groups was weakened so that the bulk crystallization size on the membrane surface was greatly reduced. The filter cake enhanced osmotic pressure effect (CEOP) and concentration polarization effect were hence alleviated, as well as the surface roughness . At the microcosmic perspective, as the energy barrier between the membrane and foulants was increased significantly after pretreatment, the anti -foulants adsorption ability of the membrane was enhanced. Correlation analysis showed that the carboxyl concentration and density, HPO ratio, larger particle size (>100 nm) ratio, the Ca 2+ concentration in the scaling layer and energy barrier all had a good correlation with the membrane resistance. This research not only provides an advanced oxidation technology that can effectively alleviate the synergistically-fouling effect of HA and Ca 2+ of nanofiltration process, but also proposes a guidance for the UV/Fe(II) synergistically activated sulfite.
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