FIBERS AND POLYMERS
·
2016
·Vol. 17
·期 11
·1782-1789
·
IF 1.022
Xu QingBo,Wu YongHong,Zhang YanYan,Fu FeiYa,Liu XiangDong
This article focuses on the functional finishing of textiles using silver nanoparticles (AgNPs) and chitosan derivative binder, which was synthesized by a modification of chitosan using α-ketoglutaric acid. The binder covalently linked to cotton fabric via esterification of the hydroxyl groups on the cotton surface, and tightly adhered to surface of the AgNPs by coordination bonds. As a result, the coating of AgNPs on the cotton fabric showed excellent antibacterial property and laundering durability. After 30 consecutive laundering cycles, the Ag content on the fabrics decreased to 37.6 %, but the bacterial reduction rates against both S. aureus and E. coli were maintained over 95 %. It has potential applications in a wide variety of fields such as sportswear, socks, and medical textile.
研究领域:
纺织科学
·
材料科学
·
生物学
✓ 已验证
DOI
高影响因子
JOURNAL OF ENVIRONMENTAL MANAGEMENT
·
2025
·
IF 8.4
Jin-Hyuk Choi,Mingi Ko,Soyeong Yoon,Narae Kim,Taesoon Jang,Myeongsong Lee,Jeong-Ann Park
A three-dimensional porous graphene oxide/chitosan (GO/CS) sponge (average pore size = 21.67 μm; pore size distribution = 0.75–319.26 μm, total pore area = 1.84 m 2 /g; and pH pzc = 5.76) was evaluated for the polystyrene (PS) NPs (hydrodynamic diameter = 31.1 ± 0.4 nm) removal from aqueous solutions. The adsorption kinetics followed a pseudo-second-order model, and intra-particle diffusion occurred in three distinct stages: film diffusion, pore diffusion, and surface sorption. Adsorption isotherms aligned best with the Langmuir model, indicating a maximum adsorption capacity of 33.30 mg/g. Thermodynamic analysis showed that PS NPs adsorption was spontaneous (ΔG° < 0) and endothermic (ΔH° > 0) within the temperature range of 283–293 K. FT-IR and XPS analyses confirmed that adsorption occurred through multiple mechanisms, including electrostatic attraction, hydrogen bonding, and π–π stacking. The adsorption behavior was significantly affected by pH, salinity, and competing ions. The highest adsorption capacity (17.99 mg/g) was observed at pH 5.5, which is close to the pH PZC (5.76) of the sponge, due to favorable electrostatic and hydrophobic interactions. As NaCl concentration increased, adsorption capacity remained stable up to 20 mM, but declined sharply above 100 mM due to PS NPs aggregation. Divalent cations, particularly Ca 2+ , significantly reduced adsorption by compressing the electrical double layer and enhancing aggregation, while monovalent cations and anions had minimal impact. The sponge was reusable after a simple squeeze-wash regeneration, achieving 83.12 % removal efficiency after 12 consecutive adsorption–desorption cycles. Compared to deionized water, real water samples exhibited similar or improved adsorption capacities, with the highest capacity observed in seawater (15.78 mg/g).
研究领域:
环境科学
·
材料科学
·
水污染控制
·
纳米毒理学
·
环境化学
·
可持续技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Research Express
·
2020
·Vol. 7
·期 8
·085403
·
IF 1.929
Yanqin Xu,Jie Liu,Shumin Guan,Aotong Dong,Yuan Cao,Changguo Chen
pH-sensitive Ag/AgO/carboxymethyl chitosan (CMCS) bacteriostatic hydrogels and Ag/AgO/CMCS/Aspirin (ASP) carrier hydrogels were prepared by Ag/AgO in situ precipitation method, and the effects of swelling, degradation, drug release and antibacterial properties of hydrogels were studied. The network of Ag/AgO/CMCS/ASP drug-loaded gels produced was mainly cross-linking by hydrogen bonding and intermolecular forces, and the cross-linking silver was mainly present in the elemental Ag and Ag2+ states. Under the condition of buffer solution pH = 7.4, the cumulative release amount of Ag/AgO/CMCS/ASP drug-loaded gel was 75.20% within 12 h, and the inhibition rate of Gram-negative Escherichia coli (E. coli) reached the maximum of 92.32%, which had broad application prospects in the medical field.
研究领域:
材料科学
·
药学
·
生物医学工程
✓ 已验证
DOI
高影响因子
RSC Advances
·
2017
·Vol. 7
·期 42
·26211-26219
·
IF 3.108
Dandan Li,Lunan Guo,Na Yang,Yao Zhang,Zhengyu Jin,Xueming Xu
The properties and functionalities of chitosan are closely related to its degree of deacetylation (DD). This study aimed to determine the DD of chitosans, which were of identical molecular weight, by a proposed electro-analytical system based on inductive methodology. Statistically significant differences in electrical parameters, including terminal voltage (U′S) and λ (the ratio of primary voltage to U′S) were observed among chitosans with different DDs. Both U′S and λ were linearly correlated with the DD value, regardless of frequency, suggesting that these electrical parameters can be used to determine the DD of chitosan. More chitosan's coils contributed to higher measurement accuracy, but the change in measurement position showed no improvement. The highest linear coefficient of determination (0.9941) between DD and U′S was obtained by the experimental transformer with 100-turn chitosan's coils at a primary voltage of 10 V and a frequency of 400 Hz. This study explored the potential of an innovative electro-analytical system to determine the DD of chitosan.
研究领域:
生物化学
·
材料科学
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2020
·Vol. 31
·期 13
·10381-10389
·
IF 2.22
Xie Houpeng,Yu Qijian,Mao Jie,Wang Sui,Hu Yufang,Guo Zhiyong
Flexible strain sensors, based on their good electrical conductivity and strain sensitivity, are widely used in wearable health monitoring, sensitive tactile information display and multi-functional robot skin. However, it is still a challenge for wearable devices to prepare conductive hydrogel with flexibility, high strain, high sensitivity and biocompatibility. Herein, we designed an interpenetrating network conductive composite hydrogel, which composed with polyaniline, double bond modified chitosan and acrylamide, has excellent strength and toughness due to its unique physically and chemically cross-linked double network. The obtained hydrogel exhibited good tensile strength (0.3 MPa), high electrical conductivity (6.97 S/m) and strain sensitivity (gauge factor 15.9). The results showed that the strain sensor could detect the movement of human joints through electrical signals, and had good stability and reproducibility, which indicated that it was expected to be used in wearable health monitoring and multi-functional robot skin.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
DOI
高影响因子
Biomaterials Advances
·
2022
·
IF 0
Xinxin Bai,Zian Feng,Song Peng,Tianyu Zhu,Lina Jiao,Ningning Mao,Pengfei Gu,Zhenguang Liu,Yang Yang,Deyun Wang
In many clinical studies, prebiotics have been used as adjuvant therapy for inflammatory bowel disease (IBD). Phellinus igniarius polysaccharide (PIP) possesses great anti-inflammatory and prebiotic activities. Herein, we developed an orally deliverable PIP-loaded chitosan-modified PLGA nanomedicine (CS-PIPP) to investigate its anti-inflammatory effect in vitro and in vivo. Dextran sodium sulfate (DSS)-induced colitis model was established to evaluate the preventive effect of CS-PIPP on IBD. This study characterized that CS-PIPP had a size of 288.7 ± 5.49 nm, positive zeta potential, and showed good stability over four weeks. The in-vitro study suggested that CS-PIPP had enhanced phagocytosis by macrophages, which could further significantly inhibit M1-like macrophages phenotype and regulate lipopolysaccharide (LPS)-induced inflammatory cytokines. The in-vivo study revealed that CS-PIPP prominently prevented intestinal inflammatory damage and protected the integrity of the intestinal barrier. Moreover, CS-PIPP increased the contents of short-chain fatty acids (SCFAs) and positively regulated the gut microbiota. Specifically, CS-PIPP reduced enteropathogenic microorganisms while increasing the beneficial microbiota, including Lactobacillus and Akkermansia , which revealed the potential of CS-PIPP as prebiotics. Generally, CS-PIPP promoted the anti-inflammatory effect of PIP, so it could be regarded as a novel and potent nanoformulation to treat IBD.
研究领域:
药理学
·
纳米技术
·
免疫学
·
胃肠病学
·
微生物学
✓ 已验证
DOI
PubMed
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2022
·
IF 5.518
Zhuo Chen,Weiwei Zhang,Zhonghua Yuan,Ziyin Wang,Ruijie Ma,Kunlin Chen
Chitosan (CS) is often used as the shell material of microcapsules due to its natural non-toxic property. However, most of traditional CS microcapsules are single chamber microcapsules with single function. In this study, phase change CS microcapsules were firstly prepared by a single coagulation method, and then photochromic nanocapsules were grafted onto the CS microcapsules to obtain strawberry CS composite microcapsules. These microcapsules could be applied in the fabric, which endows it with good photochromic and antibacterial performances based on photochromic nanocapsules and CS shell of microcapsules. Through adjusting the covering density of nanocapsules on the CS microcapsules, the color-changing performance and antibacterial ability could be regulated. Moreover, it exhibited a good durable color-changing property even after repeatedly color fatigue resistance test, and the obtained multifunctional fabric is capable of thermal insulation property owing to the phase material in the microcapsules. This study provides guide for the preparation of CS-based microcapsules and high-performance textiles.
研究领域:
材料科学
·
纺织工程
·
纳米技术
✓ 已验证
DOI
高影响因子
MATERIALS & DESIGN
·
2022
·
IF 9.417
Yutong Yang,Haichao Wu,Qiliang Fu,Xinfeng Xie,Yongming Song,Min Xu,Jian Li
Fused deposition molding (FDM) can complete most complex preparation of drug delivery implants to meet the personalized needs of patients. However, the drug activity has strict requirements on processing temperature and preparation method of filaments, the implant also has strict biocompatibility requirements for the materials. In this study, a drug delivery implant was prepared with good biocompatibility, controlled and efficient drug release using FDM printing for personalized administration. Drug-loaded filaments were developed for FDM process by hot-melt extrusion (HME). Polycaprolactone was used as a drug delivery carrier, and ibuprofen as the model drug. Notably, chitosan was dissolved to form controlled and efficient release channels. The printability, changes in physical and chemical properties during HME and FDM processes of the filament, and drug release behavior, mechanism and biocompatibility of the implants were investigated. The results showed that the filament tensile strength decreased with the increase of drug and chitosan content. No obvious degradation and chemical change occurred during the whole process. The drug release efficiency could reach>99% and lasted for 120 h mainly via the diffusion - erosion mechanism. The viability of cells cultured for 24 h in 72 h, 100% implant extract was 75.3%.
研究领域:
药学
·
生物医学工程
·
材料科学
·
药物递送系统
✓ 已验证
DOI
高影响因子
JOURNAL OF NANOPARTICLE RESEARCH
·
2013
·Vol. 15
·期 9
·1-9
·
IF 2.175
Chen Zhanguang,Wang Zhen,Chen Xi,Xu Haixiong,Liu Jinbin
In this contribution, novel chitosan-stabilized gold nanoparticles (AuNPs) were prepared by mixing chitosan with citrate-reductive AuNPs under appropriate conditions. The as-prepared chitosan-stabilized AuNPs were positively charged and highly stably dispersed in aqueous solution. They exhibited weak resonance light scattering (RLS) intensity and a wine red color. In addition, the chitosan-stabilized AuNPs were successfully utilized as novel sensitive probes for the detection of heparin for the first time. It was found that the addition of heparin induced a strong increase of RLS intensity for AuNPs and the color change from red to blue. The increase in RLS intensity and the color change of chitosan-stabilized AuNPs caused by heparin allowed the sensitive detection of heparin in the range of 0.2–60 μM (~6.7 U/mL). The detection limit for heparin is 0.8 μM at a signal-to-noise ratio of 3. The present sensor for heparin detection possessed a low detection limit and wide linear range. Additionally, the proposed method was also applied to the detection of heparin in biological media with satisfactory results.
研究领域:
纳米技术
·
分析化学
·
生物传感器
✓ 已验证
DOI
PubMed
高影响因子
FIBERS AND POLYMERS
·
2022
·Vol. 23
·期 10
·2707-2716
·
IF 2.347
Zhu Shengyu,Pei Jiliu,Song Yukang,Liu Yu,Xue Feng,Xiong Xiaohui,Li Chen
This study aimed to improve the physicochemical properties of chitosan (CS) film by riboflavin (RF)-induced cross-linking under ultraviolet (UV) light for different times (0, 2, 4, 6 h). It was found that the water vapor resistance, tensile strength, optical property, and thermal stability of the film were significantly enhanced under RF-induced photo-crosslinking, especially when illuminated for 6 h. Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) verified the molecular bonding of CS and RF, as well as scanning electron microscope (SEM) showed a tighter and more uniform film structure was formed through UV crosslinking. Thus, the CS-RF films have the potential to replace petrochemical materials as a novel type of environmentally friendly packaging material.
研究领域:
材料科学
·
高分子化学
·
环境科学
✓ 已验证
DOI
高影响因子
COMPOSITES COMMUNICATIONS
·
2022
·
IF 7.685
Qiaoyun Wu,Ling Wang,Peng Ding,Yaling Deng,Oseweuba Valentine Okoro,Amin Shavandi,Lei Nie
In this study, medical hydrogels (TGs) were fabricated based on thiolate-modified chitosan (TCS) and methacrylate gelatin (GelMA) using the Thiol-Michael addition reaction. The hydrogels were formed via the Michael reaction between TCS and GelMA and determined to have an equilibrium swelling rate of more than 1100% while simultaneously providing a moist environment for the wound, and limiting crust formation. The porosity of the prepared hydrogel was also shown to have a positive correlation with the concentration of the thiolated chitosan in the formulation. A positive correlation between hydrogel strain and stress properties and increasing concentrations of thiolated chitosan was also observed. The cytocompatibility of the prepared hydrogels was also tested and confirmed using CCK-8 assay after 5 days of culture, and the best antimicrobial properties were observed with the hydrogel containing TCS and GelMA in the mass ratio of 1:2. The present study was, therefore, able to highlight the potential of a simple and low-cost approach to developing cytocompatible hydrogels with antibacterial properties and tunable mechanical properties based on the well-studied GelMA. This study implies that the produced hydrogels can have future applications in fabricating skin wound healing dressings.
研究领域:
生物材料学
·
医学工程
·
组织工程
✓ 已验证
DOI
高影响因子
CHEMISTRY-A EUROPEAN JOURNAL
·
2016
·Vol. 23
·期 16
·3850-3862
·
IF 5.771
Tuan-Wei Sun,Ying-Jie Zhu,Feng Chen
Graphical Highly flexible multifunctional biopaper with superior mechanical properties, comprising chitosan and high-weight-fraction ultralong hydroxyapatite nanowires (UHANWs/CS) is reported. This material is promising for various biomedical applications such as wound dressing, bone-fracture fixation, and bone-defect repair. Highly flexible multifunctional biopaper comprising ultralong hydroxyapatite nanowires and chitosan (UHANWs/CS), with high weight fractions of ultralong hydroxyapatite nanowires (UHANWs) up to 100 wt. %, is reported. The as-prepared UHANWs/CS composite biopaper has high flexibility and superior mechanical properties even when the weight fraction of UHANWs is as high as 90 wt. %. In contrast, the control samples consisting of hydroxyapatite nanorods and chitosan (HANRs/CS) with weight fractions of HANRs higher than 66.7 wt.% cannot be obtained in the form of the flexible membrane. The ultimate tensile strength and Young's modulus of the UHANWs/CS composite biopaper are about 3.2 times and 4.3 times those of the HANRs/CS membrane with the same weight fraction of HAP, respectively. In addition, the UHANWs/CS composite biopaper (90 wt. % UHANWs) can be used for color printing using a commercial ink-jet printer. The surface wettability, swelling ratio, and water vapor transmission rate of the UHANWs/CS composite biopaper are adjustable by changing the addition amount of UHANWs. In vitro experiments indicate that the UHANWs/CS composite biopaper has good degradability, high acellular bioactivity and high biocompatibility. The as-prepared UHANWs/CS composite biopaper is therefore promising for various biomedical applications such as wound dressing, bone-fracture fixation, and bone-defect repair.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）