Advanced Sensor Research
·
2024
·
IF 0
Wei Ye,Yaxin Li,Xinyu Zhao,Yaocheng Yang,Xin Wang,Dongqing He,Lu Li,Dongyan Tang,Tengling Ye
This study introduces a novel fluorescent light-up electrospun membrane, integrating PbBr 2 , which serves as an exceptionally selective probe for the detection of cesium ions (Cs + ). Leveraging the superior optical properties of CsPbBr 3 perovskite nanocrystals (PNCs), the researchers employ electrospinning technology to fabricate a test strip, namely PbBr 2 @polyacrylonitrile (PbBr 2 @PAN) nanofiber membranes, capable of swiftly detecting Cs + in water merely by observing changes in the nanocrystals' luminescence with the naked eye. By the introduction of NH 4 + -modified montmorillonite (NH 4 + -MMT), PbBr 2 -MT@PAN nanofiber membranes is obtained. The selectivity and sensitivity to Cs + can be further improved because NH 4 + -MMT endows PbBr 2 -MT@PAN nanofiber membranes with the hydrophilic property and selective adsorption toward Cs + ions. The membrane's fabrication is simple, scalable, and cost-effective, with high cesium selectivity and sensitivity down to 44 ppb. This innovation enables efficient, on-site cesium monitoring critical for environmental safety and nuclear waste management.
研究领域:
分析化学
·
材料科学
·
环境监测
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DOI
JOURNAL OF LIPOSOME RESEARCH
·
2026
·
IF 4.7
Li Zhang,Yize Lv,Xuedi Weng,Yan Gao,Jie Gao,Xia Cao,Michael Adu-Frimpong,Qilong Wang
Chitosan-polyethylene glycol (CS-PEG)-modified long-circulating liposomes were developed and loaded with tanshinone I (TaI@CS-PEG-L) to overcome its poor solubility and low bioavailability, as well as enhance the lipid-lowering efficacy of atorvastatin (At) and mitigate its tissues toxicity. After synthesis of CS-PEG copolymer, it was characterized with infrared and proton nuclear magnetic resonance. Thin-film hydration was used to prepare TaI@CS-PEG-L before optimization was performed using Box-Behnken design. Optimal liposomal formulation was obtained when mass ratio of lecithin:cholesterol:TaI mass ratio was 12:1:1 along with 0.2% CS-PEG, which displayed appropriate particle size (117.41 nm), polydispersity index (0.182), zeta potential (+17.31 mV), encapsulation efficiency (93.15%), and drug loading (5.19%). Besides, the liposomal preparation exhibited good long-term storage stability (over 30 days at 4 °C and 25 °C) and satisfactory gastrointestinal stability in simulated gastric (pH 1.2) and intestinal (pH 6.8) fluids for 4 h. TaI@CS-PEG-L displayed increased cellular uptake and in vitro release compared with free TaI and unmodified liposomes. Regarding pharmacokinetic studies, TaI@CS-PEG-L increased AUC0-ₜ, t1/2, and Cmax in rats by 7.26-fold, 2.43-fold, and 3.12-fold, respectively, which indicates significantly enhanced oral bioavailability. TaI@CS-PEG-L monotherapy markedly lowered serum lipid levels in hyperlipidemic mice, thereby improving liver function indices, and alleviating pathological liver injury. TaI@CS-PEG-L demonstrated synergistic lipid-lowering effects and efficiently reversed At-induced hepatic and pancreatic injuries after combination with At, thus outperforming free TaI and TaI@L. Therefore, CS-PEG-modified long-circulating liposomes could efficiently address delivery challenges of TaI, thereby yielding a formulation that could potently lower serum lipid levels and protect liver against injury. The findings of this study offer a promising ‘efficacy-enhancing and toxicity-reducing’ strategy for potential treatment of hyperlipidemia in the clinics.
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高影响因子
Processes
·
2026
·Vol. 14
·期 12
·1998
·
IF 3.4
Zhuangzhuang Zhang,Lingling Ma,Yang Shao,Diandou Xu,Min Luo
To tackle the environmental challenges associated with industrial oily wastewater discharges and recurrent marine oil spill incidents, developing high-efficiency oil–water separation technologies represents a pressing environmental challenge. This research presents a novel design approach comprising the deposition of a stable SiO2anchoring layer followed by the fabrication of a PDA/CS crosslinked coating, thereby achieving successful construction of a superhydrophilic/underwater superoleophobic (SH/UWSO) coating on stainless steel meshes (SSM). In the first step, SiO2microspheres were deposited via vapor deposition to create a micro-rough surface architecture. Subsequently, a dopamine/chitosan (DA/CS) reaction solution was introduced to form a Polydopamine/chitosan (PDA/CS) coating, yielding a SiO2@PDA/CS-SSM separation membrane. The resulting membrane exhibited separation efficiencies surpassing 99% for various oil–water mixtures, achieving a flux of 1.24 × 105L·m−2·h−1in petroleum ether systems. Notably, the membrane maintained high efficiency and structural stability even after 25 separation cycles, immersion in strong acid and base solutions for 72 h, and 100 abrasion tests. The rational design of the anchoring and crosslinking layers endows SiO2@PDA/CS-SSM with high efficiency and stability, making it an effective oil–water separation material.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2026
·
IF 4.8
Xiaoye Wen,Chenjie Pang,Chenxi Dai,Zhefeng,Fan
As novel energy level-tunable photocatalysts, copper nanoclusters (CuNCs) have been used for combining with conventional catalysts to synergize enhanced the catalytic capabilities. However, conventional photocatalysts have their own drawbacks. In particular, their fixed energy levels are unfavorable for regulating the energy level structure of composite catalysts. In this study, a novel nanoplatform (CuNCs@CS/MOF) was constructed for the detection and photocatalytic degradation of MBT. The chitosan-modified CuNCs were encapsulated within the MOF matrix. The CuNCs maintained an aggregated state and the rotation of their ligands was restricted, thereby further enhancing the photoluminescence intensity and photostability of CuNCs. When exposed to light irradiation, CuNCs@CS/MOF showed remarkable photocatalytic activity, and the underlying mechanism governing the photocatalytic degradation process was elaborated in detail. Specifically, CuNCs@CS/MOF generated photogenerated electrons and holes, the photogenerated electrons reacted with H 2 O 2 to produce ·OH, while the remaining holes accepted electrons donated by MBT. The generated ROS oxidized TMB to oxidized TMB (oxTMB) under light irradiation, which was thereafter diminished by MBT. On this basis, the quantitative detection of MBT was established. Furthermore, ROS could oxidize and decompose MBT into small-molecule fragments, thus achieving the efficient elimination of MBT. This work provides an attractive strategy for designing multifunctional novel nanoplatform, which can be applied for the accurate detection and further harmless treatment of pollutants.
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高影响因子
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
·
2025
·
IF 6.2
Shan Cao,Zhiqiang Chen,Ziyue Tang,Yingquan Chen,Mingwei Xia,Haiping Yang,Wei Chen,Xu Chen,Hanping Chen
Potassium-assisted biomass pyrolysis is highly efficient for product poly-generation and upgrading. In this study, kinetics modeling of over-saturated potassium (K 2 CO 3 )-assisted lignocellulose pyrolysis process was carried out by using the modified Friedman-based master plot (MF-MP) method combined with multiple-parallel compensation-simplified distributed activation energy model (CS-DAEM). The effects of K 2 CO 3 dosage on the lignocellulose pyrolysis process were also studied. MF-MP results show that all the K 2 CO 3 -assisted pyrolysis processes of cellulose, xylan, and lignin obey the Avrami-Erofeev (Am) nucleation mechanism, where potassium slightly decreases the activation energies. The potassium-assisted pyrolysis process of typical lignocellulose (bamboo) also obeys the Am mechanism, and 3G-Am-CS-DAEM modeling of the processes achieves R 2 > 0.999. By fixing the pre-exponential factor, the compensation effect was simplified. Based on modeling results, the activation energy decreases as potassium dosage increases from 0.01 mmol/g to 10 mmol/g. This study provides an effective kinetics approach to characterize the potassium-assisted biomass pyrolysis process.
研究领域:
能源植物学
·
化学工程
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高影响因子
Journal of Materials Chemistry C
·
2019
·Vol. 7
·期 30
·9203-9210
·
IF 6.641
Y. Y. Zhou,E. H. Song,M. G. Brik,Y. J. Wang,T. Hu,Z. G. Xia,Q. Y. Zhang
Mn4+-doped fluoride red-emitting phosphors have been developed for backlighting white light-emitting diodes (WLEDs). However, the long fluorescence lifetime (τ > 5 ms) leads to the image-retention phenomenon for the human eye when Mn4+ is doped into equivalent X sites in A2XF6 (A = Na, K, Rb, Cs; X = Si, Ge, Ti, Zr). Herein, we report on novel red-emitting A2NaScF6:Mn4+ (A = K, Rb, Cs) (ANSF) phosphors with short fluorescence lifetimes (τ < 4 ms) and characteristic zero phonon line (ZPL) emission, which can be realized via non-equivalent doping of Mn4+ into Sc3+ sites. Density functional theory (DFT) calculations verified the formation of a slightly distorted environment of Mn4+ and an Na+ vacancy to balance the charge with Mn4+ non-equivalent doping. The WLED backlight using ANSF as a red-light component can reach a wide color gamut above 105% of the National Television Standards Committee (NTSC) standard, and the image-retention on the backlighted screen can be effectively avoided compared to the backlight obtained using commercial K2SiF6:Mn4+. Such a Mn4+ non-equivalent doping strategy opens a new perspective for the modification of local symmetry and enhancement of the luminescence properties of Mn4+-doped red-emitting fluoride phosphors.
研究领域:
材料科学
·
光学工程
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DOI
高影响因子
ADVANCED MATERIALS
·
2025
·
IF 26.8
Changjiang Shi,Haihua Zhang,Haolun Li,Hongbing Fu
Blue-green lasers are essential for next-generation optoelectronics. While GaN-InGaN lasers offer excellent performance, their complex fabrication and challenges in precise bandgap tuning remain significant limitations. Hybrid lead halide perovskites present a promising alternative, with tunable bandgaps and cost-effective solution processing. However, halide migration in these materials causes spectral instability and luminescence shifts under operational conditions. Here, a novel class of Rb-Cs alloyed quasi-2D perovskites is introduced that achieve both low amplified spontaneous emission (ASE) thresholds and exceptional spectral stability. By precisely tuning the Rb-Cs ratio, it realizes ASE across the blue-green spectrum (481–532 nm). Rb-Cs alloying critically modulates the quantum well distribution, optimizes the energy landscape, and suppresses Auger recombination, resulting in a record-low ASE threshold of 1.94 µJ·cm −2 —over 50% lower than that of mixed-halide perovskites. These materials exhibit remarkable spectral robustness, with ASE spectra remaining stable even after prolonged thermal annealing, thereby overcoming halide migration-induced degradation. Furthermore, micro-ring laser arrays fabricated from these Rb-Cs alloyed perovskites demonstrate superior lasing characteristics, including high-quality whispering-gallery-mode resonances and low lasing thresholds, underscoring their potential for advanced laser technologies.
研究领域:
光电子学
·
材料科学
·
光子学
·
半导体激光器
·
钙钛矿光电器件
·
激光技术
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高影响因子
Foods
·
2025
·Vol. 14
·期 13
·2345
·
IF 5.1
Yifei Guo,Xinyu Yu,Rongrong He,Jianfei Pei,Haiming Chen,Weijun Chen
Ferulic acid (FA) exhibits beneficial properties in ulcerative colitis (UC) pathogenesis, while sensitivity to the environment and enzymes limits its use in UC therapy. Therefore, this study aims to develop a colon-targeted nanocomplex delivery system using FA and investigate its protective effects and underlying regulatory mechanisms in UC mice. A novel Zein/FA–pectin (PEC)/chitosan (CS) nanocomplex was successfully fabricated in this study. Through systematic adjustment of the PEC/CS-to-Zein/FA ratio, optimal encapsulation efficiency (60.1%) and loading capacity (26.2%) were achieved. The characterized data indicated that hydrogen bonds, electrostatic interactions, and hydrophobic forces were the main driving forces maintaining the formation of the nanocomplexes, accompanied by alterations in the secondary structure of Zein. The Zein/FA–PEC/CS nanocomplexes demonstrated excellent thermal/storage particle size stability and exhibited both protective and sustained-release effects of FA during simulated gastrointestinal digestion. Furthermore, the results demonstrated that the nanocomplexes potentially alleviate UC by regulating inflammatory cytokines, oxidative stress, and gut microbiota. Compared to unencapsulated FA, the nanocomplexes have a better effect on alleviating UC symptoms. In summary, Zein/FA–PEC/CS nanocomplexes have promising prospects in alleviating colitis in UC mice.
研究领域:
生物医学
·
药剂学
·
食品科学
·
免疫学
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Tingxiang He,Xiang Liu,Shenghua Lv,Dequan Wei,Leipeng Liu
The abuse of antibiotics led to significant environmental pollution through persistent residues in water bodies, posing severe risks to both ecological systems and human health. Addressing this issue, recent studies highlighted the potential of carbonaceous materials as effective adsorbents for removing antibiotics from water. Despite the proven potential of various carbonaceous materials in water purification, the application of three-dimensional porous microspherical aerogels as adsorbents presented a promising yet comparatively less discussed avenue in the quest for efficient antibiotic removal from aquatic environments.This work introduced a novel KGM-GO/CS/SA composite aerogel sphere, developed via a simple sol–gel and dripping method, using konjac glucomannan (KGM) as a cross-linking agent. We extensively analyzed its adsorption efficiency against common antibiotics such as tetracycline (TC), ofloxacin (OFL), and sulfadiazine (SDZ), revealing its rapid adsorption kinetics and high capacity. The aerogel's micro-morphology, characterized by a graded porous structure with abundant microporous channels and a low bulk density of 21.2 mg/cm3, along with its enhanced mechanical properties and thermal stability due to KGM cross-linking, signified its potential as a robust adsorbent. The surface functional groups facilitated diverse interaction mechanisms, including electrostatic attraction, hydrogen bonding, and π-π interactions, contributing to the adsorbent's high performance. Furthermore, the surface charge of the aerogel varied with pH, enhancing its electrostatic adsorption capabilities. The adsorption behavior was best described by the quasi-second-order and Langmuir models, with maximum capacities of 427.63 mg/g for OFL, 374.35 mg/g for TC, and 231.09 mg/g for SDZ, thereby offering a promising solution for antibiotic pollution remediation and illustrating the utility of carbon-based aerogel microspheres in environmental applications.
研究领域:
材料科学
·
环境科学
·
生物医学工程
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高影响因子
PROGRESS IN ORGANIC COATINGS
·
2020
·
IF 4.469
Nan Zheng,Jie Liu,Yuhang Wang,Chunmei Li,Qiuyu Zhang
Self-healing coatings healed by the synergistic action of ultraviolet light and moisture are developed. Firstly, a polysiloxane-based healing agent, containing acryloyloxy (CH 2 =C(CH 3 )COO-)and methoxy silane(-SiOCH 3 )groups, is synthesized and encapsulated in chitosan-reduced graphene oxide (CS-RGO) microcapsules with compact CS-RGO shell structures. The CS-RGO microcapsules containing the polysiloxane core are then embedded in epoxy-modified silicone resin to achieve efficient self-healing coatings. Herein, an assembly time of 2.5 h results in a complete stacking of GO sheets on the emulsion droplets. As the CS/GO ratio increase, the reduction degree of GO, the sphericity of the CS-RGO microcapsules, and the average diameter all increase. Moreover, the compact CS-RGO shell formed by the assembly and stacking GO sheets as well as the interactions between CS and GO helps to maintain effectiveness of the core and stability of the microcapsules. The result shows that embedding of the CS-RGO microcapsules in the resin matrix improves the mechanical properties and anti-corrosion properties of the matrix. What’s more, the self-healing coatings with the UV/moisture dual healing mode is beneficial for achieving superior self-healing effects, which is promising for various industries, especially the over-water construction of ships, bridges, pipelines, etc.
研究领域:
材料科学
·
化学工程
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DOI
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2017
·
IF 4.164
Chili Zhao,Xun Liu,Xia Zhang,Hong Yan,Zhilei Qian,Xinghui Li,Zhenye Ma,Qiaorong Han,Chonghua Pei
In this paper, Fe 3 O 4 /chitosan/isoniazid magnetic nanoparticles (Fe 3 O 4 /CS/INH-MNPs) were prepared as an environmental stimuli-responsive drug-delivery system by automated in situ click technology, in which Fe 3 O 4 magnetic nanoparticles, chitosan and isoniazid were simultaneously in situ crystallized by one-step method. The Fe 3 O 4 magnetic nanoparticles and tripolyphosphate act as stable crosslinkers to produce numerous intermolecular crosslinkages for the mobility of the chitosan chains. Characterization results indicated that the multifunctional drug delivery system with optimized size, excellent loading capacity, well magnetic properties, nontoxicity and pH triggered drug release property is expected to be applied in tuberculosis treatment with excellent magnetic sensitivity and sustained release.
研究领域:
药学
·
生物医学工程
·
纳米医学
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DOI
高影响因子
LANGMUIR
·
2026
·
IF 4.4
Zhihai Wu,Gongxuan Lu
The highly efficient enrichment of Li+ and Cs+ from their low-concentration aqueous solutions is a crucial step for Lithium and Cesium clean production, as well as radioactive Cs+ safety remediation from water. The current adsorption and precipitation routes are high energy cost and environmental unfriendly. Electrochemical ion exchange route may serve as a promising alternative route. This study presents results of high efficient, multicycle Li+ and Cs+ enrichment from their low concentration solutions via intercalation and deintercalation in WO3/GaAs composite electrode with Faraday efficiency above 99% and high intercalation capacities 7.25 mg/g for Li+ and 38.89 mg/g for Cs+, respectively. After six cycles, 95 and 90% capacities for Li+ and Cs+ still remained. Both enrichment efficiency and stability are higher than those of LiFePO4 (LFP) and LiMn2O4 (LMO) under the same conditions. This route might provide a way for low-energy cost and highly efficient Li+ and Cs+ recovery from contaminated water.
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高影响因子
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