SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Haining Hou,Zehao Zhang,Haibo Li
Capacitive deionization (CDI) is a highly efficient desalination technique to obtain the portable water with low energy cost and environmental-friendly. However, the desalination capacity is still challenging. In this work, a Cu@C anode presenting the spherical structure with plenty of 3D diffusion tunnels has been proposed for CDI anode towards the enhanced Cl - removal. Such structure not only provide abundant electroactive sites for adopting salty ions, but also promote the electrosorption kinetics. Aiming to extract Cl - from the stream, the optimized Cu@C // activated carbon CDI device demonstrates the exceptional desalination capacity of 149.14 mg/g at 1.4 V in 529 ppm NaCl solutions as well as the fast desalination rate of 8.32 mg/g/min, which are relatively high as compared to many reported data. Moreover, the mechanism analysis points out that the desalination behavior of Cu@C electrode is dominantly governed by the conversion of Cu 0 and Cu + . Beyond that, the desalination capacity decay upon the long cycles is attributed to the irreversible Cu-Cl bonds.
研究领域:
材料科学
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环境工程
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产品关联
DOI
高影响因子
LANGMUIR
·
2024
·
IF 3.7
Yuyun Wang,Guoliang Zhang,Duo Yang,Yang Li,Wei Yin,Jingshui Xu
At present, Ni-based coatings are rarely used in the field of voltage control friction because of their poor antifriction, wear resistance, and conductive properties. Therefore, in this paper, Cu-BTC@Ag nanocrystals were used to enhance the nickel coatings, and the effect of voltage on their tribological properties was also investigated. It was found that the grains of coating were refined via the addition of Cu-BTC@Ag nanocrystals, leading to an improvement in the hardness and corrosion resistance of this composite coating. The tribological performance of nickel composite coating could be controlled under different electrical fields. With the comparison of the pure Ni-based coating, the average friction coefficient and wear volume of its composite coating with 5 wt % Cu-BTC@Ag were reduced by 7.0 and 91.8%, respectively, which showed excellent wear resistance without an applied voltage. Under the condition of 20 V, the 5 wt % Cu-BTC@Ag/Ni-based composite coating owned outstanding antifriction performance. Therefore, Cu-BTC@Ag played an intelligent role in regulating the friction of Ni-based coatings under an external voltage. It is due to the accumulation of Cu-BTC@Ag nanocrystals on the surface of the coating under the action of voltage, which played the role of supporting load and effectively reducing wear.
研究领域:
材料科学
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表面工程
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产品关联
DOI
PubMed
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2025
·
IF 3.9
Lei Wu,Xiuyun Ma,Xiumei Liu,Hong Du,Feng Wang
Hydrogenation of xylose is an important industrial process for the production of xylitol, which is known as a healthy sweetener. In this work, bimetallic phyllosilicate-derived Cu–Ni alloy catalysts were constructed via an ammonia evaporation method followed by reduction under hydrogen and applied for the hydrogenation of a high-concentration xylose aqueous solution for the production of xylitol. The Cu–Ni alloy catalysts exhibited higher xylose conversion than the corresponding monometallic Cu and Ni catalyst. And the xylitol yield was increased with the increase of the ratio of nickel to copper for the bimetallic alloy catalyst. The higher xylose conversion was obtained at elevated reaction temperature and H2 pressure. In addition, reduction conditions, especially temperature, were found to significantly influence the catalytic activity of the phyllosilicate-derived Cu–Ni alloy sample. The 5Cu15Ni-EA catalyst activated at 700 °C exhibited excellent performance for xylose hydrogenation in terms of xylose conversion (>99%) and xylitol selectivity (>99%) under moderate conditions (100 °C and 4 MPa H2). The performance of the 5Cu15Ni-EA catalyst is also superior to the reported consequences of xylitol manufacture via hydrogenation over a Raney nickel catalyst and a co-impregnation-derived bimetallic catalyst. Furthermore, the xylitol yield did not change obviously for 5Cu15Ni-EA during the 200 h of continuous reaction in a fixed bed reactor. The XRD, XPS, HRTEM–EDS mapping, and line scan results of the fresh reduced 5Cu15Ni-EA sample verified the existence of a highly dispersed Cu–Ni alloy. The formation of these uniformly dispersed Cu–Ni alloy sites induced efficient performance for the hydrogenation of a high-concentration xylose aqueous solution.
研究领域:
化学工程
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催化材料科学
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产品关联
DOI
高影响因子
FUEL
·
2024
·
IF 6.7
Wei Fu,Muhammad Kashif,Chen Cai,Jiayin Chen,Hao Zhou,Bingtao Zhao,Philippe M. Heynderickx,Yaxin Su
The hydrothermal technique was applied to prepare a new metal–organic framework, MIL-100(Fe), which was modified by ultrasonic impregnation with different wt % of copper. The results showed that the NO x conversion over 2.3Cu-MIL-100(Fe) was 100 % at 275 °C and maintained at ≥ 85 %, with N 2 selectivity ≥ 90 % in the temperature range of 275–400 °C and high SO 2 resistance. An increase in the Cu content up to 2.3 wt% showed the highest surface area (1206 m 2 /g) observed in N 2 adsorption–desorption. The results show that the introduction of Cu increased the oxygen vacancies on the catalyst surface. Electron transfer and a synergistic effect were observed between Cu and Fe. The shift of the reduction peaks to lower temperatures after the addition of Cu confirmed that Cu improved the reducibility of the catalysts. The 2.3Cu-MIL-100(Fe) exhibited the highest Lewis content (44.97 μmol/g), which functions as an active site for the selective catalytic reduction (SCR) reaction. By precisely controlling the acid-base properties of the catalyst, the specificity for the desired products can be increased in complicated reaction systems, especially in hydrocarbon-SCR technology.
研究领域:
材料科学
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环境科学
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催化化学
✓ 已验证
DOI
高影响因子
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
·
2025
·Vol. 44
·期 1
·1-25
·
IF 12.8
Wang Pengyu,Guo Weihua,Liu Shuyue,Li Shouyi,Li Jiaqi,Ding Bowen,Yin Fengyi,Yang Yang,Li Xingjiang,Cao Pei,Ma Chaozhe,Zhang Wanying,Song Yidan,Geng Yating,Liu Lantao,Hu Jing,Hao Jihui,Feng Yukuan
Background Copper accumulation triggers mitochondrial-driven cell death, known as cuproptosis, offering a promising mechanism for targeted cancer therapy. Recent studies have highlighted the critical role of intratumoral copper levels in regulating the expression of programmed cell death ligand-1 (PD-L1), suggesting that copper-induced cuproptosis not only enhances cancer cell death but may also amplify the effects of anti-PD-L1 antibodies (αPD-L1). However, in tumors where monotherapy with αPD-L1 shows limited efficacy, particularly in pancreatic ductal adenocarcinoma (PDAC), the role of copper-induced cuproptosis in enhancing αPD-L1 treatment efficacy and its underlying mechanisms remain unclear. Meanwhile, inadequate tumor drug accumulation and glycolysis significantly restrict the efficacy of cuproptosis. To address these challenges, we have synthesized a novel nanozyme, Pt@PCN-Cu, designed to stabilize intracellular copper accumulation and effectively induce cuproptosis. Additionally, we aim to determine whether this strong induction of cuproptosis can synergize with αPD-L1 to enhance cancer therapy, ultimately paving the way for novel strategies to improve PDAC treatment. Methods Pt@PCN-Cu was synthesized via a one-pot method, and its therapeutic potential was assessed in combination with αPD-L1 for the treatment of PDAC. Initially, the material’s properties were characterized, and its efficient cellular uptake was confirmed. Anti-tumor efficacy was evaluated by inducing cuproptosis in PDAC cell lines and xenograft models. RNA sequencing (RNA-seq) was utilized to identify key regulators involved in the modulation of PD-L1 expression by cuproptosis. Lastly, the therapeutic efficacy of Pt@PCN-Cu combined with αPD-L1 was evaluated in vivo, focusing on tumor growth inhibition and immune modulation within the tumor microenvironment (TME). Results Pt@PCN-Cu demonstrates excellent physicochemical properties and remarkable cascade catalytic activity, providing a solid foundation for further in vitro and in vivo studies. In vitro, Pt@PCN-Cu efficiently transports copper and induces cuproptosis primarily through mitochondrial dysfunction. Mechanistic studies show that Pt@PCN-Cu triggers the dissociation of hexokinase 2 (HK2) from mitochondria, leading to a reduction in HK2 activity. This decline in HK2 activity impairs glycolysis, a metabolic pathway essential for tumor energy metabolism, which in turn results in elevated PD-L1 levels. In vivo, Pt@PCN-Cu demonstrates excellent safety and accumulates at the tumor site in a subcutaneous PDAC mouse model, inducing cuproptosis. Moreover, the combination of Pt@PCN-Cu with αPD-L1 further enhanced its therapeutic efficacy and effectively reprogrammed the immunosuppressive TME. Conclusion This study presents strong evidence confirming the safety and therapeutic potential of Pt@PCN-Cu in PDAC treatment. Importantly, Pt@PCN-Cu not only induces cuproptosis but also significantly enhances antitumor efficacy in combination with αPD-L1 by regulating PD-L1 expression through HK2 modulation. These findings underscore a more effective and innovative approach for treating PDAC.
研究领域:
肿瘤学
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分子生物学
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免疫学
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纳米医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Fangxian Wang,Junwei Yang,Shihao Li,Junwen Liang,Yuwei Wang,Rong Du,Bo Zhou,Qiong Liu,Changping Li
Bromate is a commonly identified carcinogenic and genotoxic disinfection byproduct in water. Electrochemical debromination is an environmentally friendly and effective approach but it often suffers the limited reducing atomic H (H*) ability and high metal catalyst dosage. In this study, a unique composite catalyst comprised of ultra-low loading Cu single atoms (0.016 wt%) and Fe 2 O 3 nanoparticles supported on a Nb 2 C MXene (denoted as Cu 0.2 /Fe 0.1 /Nb 2 C) was synthesized by one-step high-temperature molten salt method. The Cu 0.2 /Fe 0.1 /Nb 2 C significantly outperformed the Nb 2 C, Cu 0.2 /Nb 2 C and Fe 0.1 /Nb 2 C counterparts in the electrochemical debromination with a 94.2 % removal efficiency of bromate. It is revealed that the introducing of Cu single atoms, efficiently promotes the adsorption of H* and inhibition of competitive H 2 evolution. The incorporation of Fe 2 O 3 nanoparticles significantly increased the electronic metal-support interaction effect between the metal components and Nb 2 C, thereby forming a noticeable electronic cloud bridge to facilitate efficient charge transfer. Ultimately, the synergistic interplay between Cu single atoms and Fe 2 O 3 nanoparticles plays a crucial role in achieving the remarkable removal performance of bromate. This work not only presents a significant instance of a synergistic catalyst involving metal single atoms and metal nanoparticles for effective electrochemical debromination but also advances the understanding of the electronic metal-support interaction.
研究领域:
环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ENVIRONMENTAL MANAGEMENT
·
2025
·
IF 8.4
Lidan Cao,Yupei Chai,Yingxing Zhang,Jielan Zhang,Junhong Wang,Rui Wu
Sulfur-containing gases produced during the utilization of petroleum fuels are the main cause of air pollution. To remove organic sulfur-containing compounds from simulated gasoline, magnetic hydrophobic Cu + -containing SBA-15 mesoporous molecular sieves (PMS-Cu + ) were prepared by magnetization of the sample, loading and reduction of copper ion and hydrophobic treatment of the sample. The composition and structure of the synthesized composites were characterized by XRD, FTIR, SEM, TEM, and XPS, which proved the successful preparation of the adsorbent PMS-Cu + . In addition, it was also investigated on the adsorption capacity of the prepared adsorbent for organic sulfur compounds in simulated gasoline and the factors affecting the desulfurization performance. Through the kinetic study of the adsorption process, it was found that the process conformed to the quasi-secondary kinetic properties, the adsorption process was dominated by chemical adsorption, and internal and external diffusion co-determined the adsorption rate. Moreover, the apparent activation energy of the adsorption process was 50.83 kJ/mol.
研究领域:
材料科学
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环境科学
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化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Jin Fang,Tao Ni,Minmin Mao,Yu Liu,Huan Liu,Lei Cao,Xueqing Yu,Bing Liu,Hadi Barzegar Bafrooei,Liang He,Yingjie Ren,Fayaz Hussain,Dawei Wang,Kaixin Song
MgSiO 3 ceramics with a low dielectric constant are highly promising for application in 5G communication due to their excellent performance and cost-effectiveness. However, the application remains constrained by phase transitions. This study aims to unlock their full potential by introducing Cu ions to mitigate phase transitions, thereby achieving stable and superior performance. Mg 1- x Cu x SiO 3 (0 ≤ x ≤ 0.25) ceramics were synthesized by solid-state method, and the effects of Cu introduction on the crystal structure, phase constitution, microstructure and microwave dielectric properties were systematically investigated. Through XRD patterns and Rietveld refinement , it was found that when x = 0, both protoenstatite (PEN) and low-temperature clinoenstatite (CEN) phases coexist due to a phase transition from PEN to CEN. As x increases, the PEN phase dominance rises while the CEN phase diminishes, indicating that the addition of Cu ions inhibits the occurrence of phase transition. At x ≥ 0.2, only the orthoenstatite (OEN) phase was observed. SEM and EDS analyses revealed the beneficial impact of Cu introduction on sintering, yet excessive amounts can lead to abnormal grain growth , local segregation, and uneven distribution of Cu elements, thereby deteriorating microwave dielectric properties . The optimal microwave dielectric performance was achieved at x = 0.05: ε r = 6.2, Qf = 93,600 GHz, τ f = −33.7 ppm/°C. A one-year long-term comparative study revealed the stabilizing effect of Cu incorporation for obtaining stable excellent performance. These findings underscore the potential of introducing an appropriate amount of Cu to achieve stable and superior microwave dielectric properties in MgSiO 3 ceramics, paving the way for practical applications in 5G communication.
研究领域:
材料科学
·
电子工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF THE ENERGY INSTITUTE
·
2024
·
IF 5.6
Zheng Bo,Mengyu Cao,Yaolin Wang,Jianhua Yan,Kefa Cen,Xin Tu
Plasma catalytic CO 2 hydrogenation has emerged as a promising approach for converting CO 2 into valuable chemicals such as CO, offering a potential solution to mitigate greenhouse gas emissions. In this study, we investigate the synergistic effect between plasma and a Cu/Ti 3 C 2 T x MXene catalyst for CO 2 hydrogenation via the reverse water gas shift (RWGS) reaction in a dielectric barrier discharge (DBD) reactor. Our findings reveal a significant enhancement in CO 2 conversion (33.1%) and CO yield (31.9%) when using the Cu/Ti 3 C 2 T x catalyst compared to plasma alone or with a Ti 3 C 2 T x foam. Plasma treatment creates unsaturated Ti sites on the Ti 3 C 2 T x surface, dramatically improving CO 2 adsorption and activation, while Cu nanoparticles significantly enhances the activation and dissociation of H 2 molecules on the catalyst surface. These surface adsorbed hydrogen species readily hydrogenate adsorbed CO 2 molecules through the Langmuir-Hinshelwood mechanism. Furthermore, these surface hydrogen species can also participate in the conversion of gas-phase CO 2 molecules through the Eley-Rideal pathway. This work sheds light on the synergistic plasma catalytic mechanism and provide insights for optimizing CO 2 hydrogenation processes using MXene catalysts.
研究领域:
化学工程
·
催化
·
环境科学
·
等离子体化学
✓ 已验证
产品关联
DOI
高影响因子
SOLAR ENERGY
·
2018
·
IF 4.374
Lianjing Zhao,Leilei Zhao,Weinan Xue,Wenjuan Fang,Yuan Wang,Yan Li
To improve the catalytic activity of carbons in counter electrodes (CEs), Cu nanoparticles (NPs) were introduced into mesoporous N-doped carbons (N-C) derived from metal-organic frameworks (MOFs) to prepare the composites of N-C and Cu NPs (N-C@Cu) via impregnation and subsequent reduction method in this work. The obtained N-C@Cu composites with 2–4 nm Cu NPs uniformly distributing in N-C were deposited onto fluorine doped tin oxide (FTO) substrates by screen-printing to fabricate CEs in quantum dot solar cells (QDSCs). The N-C@Cu CEs exhibit higher electrocatalytic activity than both pristine N-C/FTO and commonly used Cu 2 S/FTO CEs, which could be ascribed to the synergistic effect between Cu x S NPs with the excellent electrocatalytic ability and MOF derived N-C with high graphitization, large hydrophilic surface as well as the abundant dopant active sites on the reduction of polysulfide. The superior performance of N-C@Cu composites results in an improved fill factor and a high short circuit current density. Based on optimized N-C@Cu CEs and Zn-Cu-In-Se quantum dot sensitizers, the QDSCs obtained present a promising power conversion efficiency of 9.23%, significantly superior to those of pristine N-C/FTO (7.20%) and Cu 2 S/FTO (8.89%) CEs based QDSCs.
研究领域:
材料科学
·
能源科学
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2024
·
IF 8.1
Guiming Xie,Xingyang Bai,Yanrui Niu,Zhangjun Bai,Qingyuan Yang,Jian Liu,Zhou-jun Wang
ZIF-8 was employed as partial Zn source to prepare high-performance Cu/ZnO/Al 2 O 3 catalysts for methanol synthesis via carbon dioxide (CO 2 ) hydrogenation. Among the CuZnAl-x catalysts (x = 1, 0.75, 0.5, 0.25 and 0, denoting molar ratio of ZIF-8/(ZIF-8 + Zn(NO 3 ) 2 ·6H 2 O), the CuZnAl-0.5 catalyst possessed the highest space time yield of methanol ( STY MeOH ), which recorded 416.4 g MeOH kg cat −1 h −1 at 250 °C and 3.0 MPa. Using ZIF-8 as partial Zn source was found to increase the specific surface area, induce oxygen vacancies, intensify metal-oxide interactions and enrich medium basic sites, which may rationalize the excellent methanol synthesis activity of the CuZnAl-0.5 catalyst. Besides, the CuZnAl-0.5 catalyst showed good stability for 30 h of reaction. This work offers a unique route to fabricate catalysts with the aid of MOFs precursors and highlights the significance of oxygen vacancies in methanol synthesis catalysts.
研究领域:
化学工程
·
催化材料科学
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Li Liu,Yuefeng Huang,Zhenqiang Kan,Yaohong Yang,Peng Wang,Yuju Chen,Dongyu Wei,Hong Lei,Guanben Du,Lianpeng Zhang
The application of biopolymers in adhesive design holds immense potential for advancing the sustainable manufacturing of high-performance materials. In this study, chitosan (CS), a renewable and biodegradable biopolymer, serves as the structural backbone for developing an innovative organic-inorganic hybrid resin Cu/ZIF-8@CS-MCS@BN. Initially, CS was chemically functionalized via crosslinking with maleic anhydride (MA) to form a maleated chitosan network (CS-MCS), exploiting the biopolymer's abundant amino and hydroxyl groups for covalent bonding. This chitosan-based network was subsequently reinforced with boron nitride nanosheets (BN) and copper-doped ZIF-8 metal-organic frameworks (Cu/ZIF-8), synergistically combining the flame-retardant and mechanical-enhancing properties of inorganic fillers with the organic network of the chitosan matrix. The Cu/ZIF-8@CS-MCS@BN resin was processed into two distinct wood composites: (1) plywood fabricated by hot-pressing poplar veneers with the resin exhibited exceptional interfacial adhesion, achieving a boiling-water-resistant shear strength of 1.01 MPa, which surpasses the requirements of the Chinese national standard GB/T 9846–2015; (2) lightweight aerogels prepared by freeze-drying resin-wood flour mixtures demonstrated outstanding compressive resistance (compressive modulus: 45.23 MPa) and fire safety (limiting oxygen index (LOI) = 42.8 %, UL-94 V-0 rating). This work establishes a green paradigm for fabricating multifunctional wood composites, highlighting the pivotal role of biopolymer engineering in next-generation construction materials.
研究领域:
生物高分子材料
·
胶黏剂设计
·
阻燃材料
·
木材加工
·
纳米材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）