ACS Applied Materials & Interfaces
·
2026
·
IF 7.8
Xingzhuo Han,Peng Wu,Yibo Wang,Xiuli Hu,Zhiyu Jia,Juan Gao
The lower thermodynamic potential of the urea oxidation reaction (UOR) makes it an ideal alternative to the conventional oxygen evolution reaction (OER). However, most Ni-based UOR catalysts face intrinsic limitations due to the high oxidation potential of Ni3+, coupled with insufficient selectivity. Herein, F/Mo codoped Ni-based catalyst F-MoNiP is obtained with an amorphous nanotube structure. The F/Mo codoped strategy enhances UOR activity by facilitating the formation of catalytically active NiOOH species at low overpotential and simultaneously promotes urea decomposition through the environmentally preferred carbonate pathway. Moreover, the presence of F effectively suppresses the OH– adsorption, thereby minimizing the competition with OER. This synergistic optimization enables F-MoNiP to achieve exceptional catalytic performance, operating at a cell voltage of 1.395 V to deliver a current density of 10 mA cm–2 in urea-assisted electrolysis of water. These findings offer a sustainable and energy-efficient route for hydrogen production through urea electrolysis.
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JOURNAL OF POWER SOURCES
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2014
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IF 5.211
Mandi Ji,Yunlong Xu,Zhen Zhao,Huang Zhang,Dong Liu,Chongjun Zhao,Xiuzhen Qian,Chunhua Zhao
La 3+ and F − co-doped Li 4 Ti 5 O 12 (LTO) anode materials are synthesized successfully via a solid state reaction. The structure and morphology are characterized by XRD , SEM and EDS . The results indicate that La 3+ and F − ions were uniformly dispersed in Li 4 Ti 5 O 12 lattice without changing the structure and morphology of Li 4 Ti 5 O 12 . Li 3.95 La 0.05 Ti 5 O 11.7 F 0.3 (La005-F03) exhibits an outstanding electrochemical performance among all the samples in a potential range from 0.5 to 2.5 V, and delivers a discharge capacity of 103 mAh g −1 at 10C rate, whereas the LTO only gives 62.5 mAh g −1 . The sample La005-F03 retains a discharge capacity of 170.1 mAh g −1 after 100 cycles at 1C rate. The improved electrochemical performance could be attributed to the appropriate co-doping with La 3+ and F − , which can increase the amount of Ti 3+ /Ti 4+ mixing as charge compensation, leading to the decrease of the charge transfer resistance and improvement of the electronic conductivity and lithium ion diffusion coefficient .
研究领域:
材料科学
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电化学
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储能技术
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无机化学
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NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
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2023
·
IF 3.6
Deng Shanshan,Gao Yuan,Lv Mengting,Li Xinyu,Ma Yulin,Guo Yuchen,Li Tiejun,Zhang Yuefan
Chronic cerebral hypoperfusion (CCH) is the leading cause of chronic cerebral dysfunction syndrome with its complex pathological mechanisms involving cortical and hippocampal neuronal loss, white matter lesions, and neuroinflammation. I-C-F-6 is a septapeptide, which has anti-inflammatory and anti-fibrotic effects. This study aimed to evaluate the neuroprotective effect of I-C-F-6 in chronic cerebral hypoperfusion (CCH)-induced neurological injury. C57BL/6 J mice were subjected to bilateral common carotid artery stenosis (BCAS), and BV2 microglia cells were induced with oxygen-glucose deprivation (OGD). In vivo, mice were divided randomly into four groups: Sham, BCAS, GBE (30 mg/kg), and I-C-F-6 (0.5 mg/kg). In vitro, microglia were divided randomly into four groups: control, OGD, I-C-F-6 (25 μg/mL), and Shikonin (800 nmol/L). Through LFB, TUNEL, and NeuN staining, we found that I-C-F-6 was able to mitigate myelin pathology and reduce the number of apoptotic neurons. Furthermore, immunofluorescence staining revealed that I-C-F-6 was able to reduce microglia clustering and downregulate NF-κB p65. We also observed a significant downregulation of M1 phenotype microglia signature genes, such as TNF-α, iNOS, and upregulation of anti-inflammatory cytokines, such as Arg-1 and IL-10, indicating that I-C-F-6 may mainly reduce polarization towards the M1 phenotype in microglia. Notably, I-C-F-6 downregulated the expression of NF-κB signaling pathway-related proteins IKK-β and NF-κB p65, as well as pro-inflammatory cytokines IL-1β and iNOS. In conclusion, I-C-F-6 can improve neurological damage, alleviate neuroinflammation, and inhibit microglia polarization to the M1 phenotype via the NF-κB signaling pathway.
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INORGANIC CHEMISTRY
·
2023
·
IF 4.6
Yuwei Chen,Pifu Gong,Ruixin Guo,Feidi Fan,Jun Shen,Guochun Zhang,Heng Tu
A new Gd3+-containing borate Ba2Gd(BO3)2F has been successfully grown via the high-temperature solution method using BaF2-NaF-B2O3 flux. Ba2Gd(BO3)2F crystallizing in the orthorhombic space group Pnma is with lattice parameters a = 7.571(4) Å, b = 10.424(5) Å, c = 8.581(4) Å, α = β = γ = 90°, and Z = 2. Its three-dimensional framework was constructed from interesting pinwheel-like [Gd(BO3)F]∞ layers bridged by sharing [BO3]3–, which is different from the [Gd(BO3)]∞ layer in the model structure Ba2Gd(BO3)2Cl. The magnetic measurements indicated that Ba2Gd(BO3)2F has a larger magnetocaloric effect with −ΔSm,max = 27.82 J·kg–1·K–1at 2 K and 9 T than that of Ba2Gd(BO3)2Cl under the same conditions. Moreover, thermal stability, infrared spectrum (IR), and ultraviolet–visible-near-infrared diffuse reflectance spectrum were carried out to characterize the title compounds. The first-principles computations also looked into the electronic band structures, densities of states, and refractive indices.
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CHEMOSPHERE
·
2018
·
IF 4.427
Yongming Wu,Mi Deng,Yuanxiang Jin,Xiyan Mu,Xiaoli He,Nha-Thi Luu,Chunyan Yang,Wenqing Tu
6:2 chlorinated polyfluorinated ether sulfonate (F-53B) has been widely applied as a mist suppressant to replace perfluorooctane sulfonate (PFOS) in the metal plating industry in China for decades. Recently, F-53B has been frequently identified in the aquatic environment and wild-caught fish. However, studies on the uptake and elimination kinetics, and the toxicological effects of F-53B were very scarce. In this study, zebrafish larvae (72 h post fertilization, hpf) were exposed to F-53B (10, 100 μ g/L) for 48 h, followed by a 24 h of depuration to examine both the dynamics of accumulation and elimination of F-53B and responses of antoxidant defense system in fish. The results showed that F-53B rapidly accumulated in zebrafish larvae in a concentration and time-dependent manner with BCF values of 3612–3615, but was eliminated slowly (half-life ranged from 241.5 to 258.6 h). F-53B exposure induced oxidative stress in zebrafish larvae, as reflected by the reduction in the GSH and MDA contents, CAT, SOD, CuZn-SOD, and GSH-ST activities, and the increase in GSH-Px activity as well as CAT and SOD protein levels. However, these oxidative stress markers were restored to control levels except for a decrease in protein level of SOD after depuration. Collectively, the results of this work indicate that F-53B behaves like PFOS and is bioaccumulative and persistent in zebrafish larvae, and further induced oxidative stress responses.
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ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Chao Yang,Na Han,Changye Han,Menglu Wang,Wenxin Zhang,Weijing Wang,Zongxuan Zhang,Wei Li,Xingxiang Zhang
Extremely asymmetric wettability, high wetting selectivity, instantaneous superwetting behaviors (low transmembrane resistance), and superior resistance to chemicals and solvents are needed for Janus membranes for switchable oil/water separation. However, it is still challenging to obtain Janus membranes with such properties. In this study, a surface with metastable hydrophobicity is constructed on one side of the chemically stable superhydrophilic TiO2@PPS membrane by adjusting the hydrophobization depth and the morphology of the hydrophobic layer via a water–oil interfacial grafting. The prepared Janus membrane exhibits a high water contact angle difference of ∼150° between its two surfaces with maintaining the superior penetrability of the original membrane, which makes it capable to separate both oil-in-water and water-in-oil emulsions with high fluxes and accuracy. The separation efficiency is higher than 98% for the separation of the two kinds of emulsions. The fluxes of the surfactant-free toluene-in-water and water-in-toluene emulsions are up to 6.4 × 102 and 9.5 × 102 L m–2 h–1, respectively. Furthermore, the Janus membrane exhibits desirable antifouling performance and reusability during usage.
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Journal of the Taiwan Institute of Chemical Engineers
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2017
·
IF 4.217
Long Huang,Weihua Luo,Meiying Liu,Jianwen Tian,Qiang Huang,Hongye Huang,Junfeng Hui,Yuanqing Wen,Xiaoyong Zhang,Yen Wei
The luminescent hydroxyapatite nanorods co-doped with Eu 3+ and F − (named as FAp:Eu 3+ ) were synthesized through liquid-solid-solution strategy to control their size and morphology as well as improve their fluorescence. However, these luminescent FAp:Eu 3+ nanorods are hydrophobic nature and cannot be directly used for biomedical applications. In this work, we developed a novel strategy for surface modification of FAp:Eu 3+ nanorods with the combination of the surface ligand exchange reaction and photo-initiated reversible addition-fragmentation chain transfer (photo-RAFT) polymerization using the biocompatible and hydrophilic poly(ethylene glycol) methacrylate (PEGMA) as the monomer. We demonstrated that the photo-RAFT polymerization is a facile and efficient route to fabricate hydrophilic FAp:Eu 3+ -polyPEGMA composites based on a series of characterization techniques. The FAp:Eu 3+ -polyPEGMA composites still well maintained the morphology and luminescent properties. Furthermore, the resultant FAp:Eu 3+ -polyPEGMA composites showed low cytotoxicity and desirable cell uptake behavior. These features suggested that the FAp:Eu 3+ -polyPEGMA composites are of great potential for biological imaging applications. More importantly, the photo-RAFT polymerization should be promising for preparation of many other luminescent nanocomposites owing to their advantages of photo-RAFT polymerization such as low polymerization temperature, high efficiency, absence of metal catalysts and good monomer applicability. It is therefore, the photo-RAFT could be extended for fabrication of many other multifunctional fluorescent composites for different biomedical applications.
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COLLOIDS AND SURFACES B-BIOINTERFACES
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2022
·
IF 5.999
Xiaodan Jiang,Xiaowei Liu,Jiayi Cai,Shibo Wei,Yanan Wang,Zhuqing Duan,Zeao Zhou,Ruixue Sun,Xiaofei Qu,Yuanzheng Tang
Due to its excellent bone conductivity and drug adsorption as well as pH-responsive drug release property, hydroxyapatite (HAp) is widely used as a drug carrier in bone repair field. Here, we report for the first time a novel multi-functional polydopamine (PDA) coated Cu/F-codoped HAp (Cu/F-HAp-PDA) hollow microspheres . Both Cu 2+ and F - were successfully doped into the lattice of HAp and uniformly distributed in the shell of hollow microspheres through a one-step hydrothermal synthesis . Then PDA was coated homogeneously on the outer layer of Cu/F-HAp hollow microspheres. Both Cu/F-HAp and Cu/F-HAp-PDA samples displayed high drug loading efficiency and pH responsive drug release behavior. Moreover, the obtained Cu/F-HAp-PDA hollow microspheres exhibited excellent photothermal conversion efficiency and photothermal stability. The molecular dynamics simulations showed that PDA and HAp can form mutual binding mainly through Ca-O bonding, while doxorubicin (DOX) is mainly bound to PDA molecules through hydrogen bonding and π-π stacking interaction.
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JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 36
·17188-17202
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IF 4.682
Ouyang Yuanyong,Zhang Zihao,Huang Wei,Yang Wenzhong,Shen Chuanlai,Chen Yun,Yin Xiaoshuang,Liu Ying
Fluorinated hydroxyapatite-titanium dioxide coating (F-doped HA-TiO 2 ) was deposited in situ onto AZ31 Mg alloy using electrodeposition method. XRD and EDS confirmed the crystal structure and composition of the coating. SEM images showed that the F-doped HA-TiO 2 coating on the surface of AZ31 Mg alloy was extremely uniform and the thickness of coating was reflected by the cross-sectional image. Corrosion behavior of the coating modified Mg alloy was tested by electrochemical and immersion experiments. Compared to the corrosion current density ( I corr ) of the uncoated AZ31 Mg alloy in Hank’s solution, the I corr of F-doped HA-TiO 2 coating was decreased almost 4 orders. The coated AZ31 Mg alloy showed superior biocompatibility, which was strongly demonstrated by the amounts of cells increased in cell culture. The results of hemolysis tests also illustrated that the F-doped HA-TiO 2 coating met the requirements of biomedical materials.
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CHEMICAL ENGINEERING JOURNAL
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2021
·
IF 13.273
Si-Wei Xiong,Qian Zou,Ze-Gang Wang,Jun Qin,Yang Liu,Nan-Jun Wei,Meng-ying Jiang,Jing-Gang Gai
Wearing surgical masks remains the most effective protective measure against COVID-19 before mass vaccination, but insufficient comfortability and low antibacterial/antiviral activities accelerate the replacement frequency of surgical masks, resulting in large amounts of medical waste. To solve this problem, we report new nanofiber membrane masks with outstanding comfortability and anti-pathogen functionality prepared using fluorinated carbon nanofibers/carbon fiber (F-CNFs/CF). This was used to replace commercial polypropylene (PP) nonwovens as the core layer of face masks. The through-plane and in-plane thermal conductivity of commercial PP nonwovens were only 0.12 and 0.20 W/m K, but the F-CNFs/CF nanofiber membranes reached 0.62 and 5.23 W/m K, which represent enhancements of 380% and 2523%, respectively. The surface temperature of the PP surgical masks was 23.9 ℃ when the wearing time was 15 min, while the F-CNFs/CF nanocomposite fibrous masks reached 27.3 ℃, displaying stronger heat dissipation. Moreover, the F-CNFs/CF nanofiber membranes displayed excellent electrical conductivity and produced a high-temperature layer that killed viruses and bacteria in the masks. The surface temperature of the F-CNFs/CF nanocomposite fibrous masks reached 69.2 ℃ after being connected to a portable power source for 60 s. Their antibacterial rates were 97.9% and 98.6% against E. coli and S. aureus , respectively, after being connected to a portable power source for 30 min.
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2021
·
IF 2.694
Qing Hao,Huan Zhou,Mengli Zhang,Si Wu,Junfang Yang
Rare-earth ore concentrate is calcined at high temperature by the alkaline method, and the associated elements fluorine and phosphorus are enriched in the form of sodium fluoride and sodium phosphate in water elution. To separate and recover fluorine and phosphorus from the aqueous solution, the solid–liquid equilibrium behaviors of the quaternary systems Na+//F–, CO32–, PO43–-H2O and their two sub-ternary systems NaF-Na3PO4-H2O and Na2CO3-Na3PO4-H2O at 313.15 K were studied via the isothermal solubility phase equilibrium method. Solubility data, liquid density and pH, two complete isothermal phase diagrams of the ternary system, and one complete isothermal phase diagram of the quaternary system were obtained. The results showed that two double salts NaF·2Na3PO4·19H2O and Na3PO4·3Na2CO3·8H2O occurred in the respective ternary systems. Five solid species of one anhydrous salt of NaF, two hydrous salts of Na2CO3·H2O and Na3PO4·12H2O, and two double salts of Na3PO4·3Na2CO3·8H2O and NaF·2Na3PO4·19H2O were found in the quaternary system. The phase diagram of the quaternary system consisted of three invariant points, five crystallization regions, and seven univariate curves. Na3PO4 easily combined with NaF to form double salt NaF·2Na3PO4·19H2O, which occupied a larger phase region in the quaternary phase diagram. The increase in Na2CO3 will lead to the decrease in the solubility of Na3PO4 and NaF in the system.
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MOLECULES
·
2021
·Vol. 26
·期 5
·1303
·
IF 4.412
Yingda Zang,Ke Liu,Weiping Wang,Chuangjun Li,Jie Ma,Jingzhi Yang,Xinyi Chen,Xiaoliang Wang,Dongming Zhang
The multifactorial nature of Alzheimer’s disease (AD) calls for the development of multitarget agents addressing key pathogenic processes. A total of 26 Claulansine F–donepezil hybrids were designed and synthesized as multitarget drugs. Among these compounds, six compounds exhibited excellent acetylcholinesterase (AChE) inhibitory activity (half maximal inhibitory concentration (IC50) 1.63–4.62 μM). Moreover, (E)-3-(8-(tert-Butyl)-3,3-dimethyl-3,11-dihydropyrano[3,2-a]carbazol-5-yl)-N-((1-(2-chlorobenzyl)piperidin-4-yl)methyl)acrylamide (6bd) exhibited better neuroprotective effects against OGD/R (oxygen–glucose deprivation/reoxygenation) than lead compound Claulansine F. Furthermore,6bdcould cross the blood–brain barrier in vitro. More importantly, compared to edaravone,6bdhad stronger free-radical scavenging activity. Molecular docking studies revealed that6bdcould interact with the catalytic active site of AChE. All of these outstanding in vitro results indicate6bdas a leading structure worthy of further investigation.Keywords:Alzheimer’s disease;Claulansine F–donepezil hybrids;AChE inhibitory activity;free-radical scavenging activity;neuroprotective effects
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