MOLECULES
·
2025
·Vol. 30
·期 1
·177
·
IF 4.6
Zhi Lu,Yifan Guo,Shilin Li,Jiaqi Ding,Yingzi Ren,Kun Tang,Jiefeng Wang,Chengxin Li,Zishuo Shi,Ziqi Sun,Hongbo Meng,Guangxin Wang
Water electrolysis is a promising path to the industrialization development of hydrogen energy. The exploitation of high-efficiency and inexpensive catalysts become important to the mass use of water decomposition. Ni-based nanomaterials have exhibited great potential for the catalysis of water splitting, which have attracted the attention of researchers around the world. Here, we prepared a novel Mo-doped NiFe-based layered double hydroxide (LDH) with a nanoarray microstructure on Ni foam. The doping amount of Mo can significantly change the microstructure of the electrocatalysis, which will further affect the oxygen evolution reaction (OER) performance of water splitting. This novel nanomaterial required only an overpotential of 227 mV for 10 mA cm−2and a Tafel slope of 54.8 mV/dec in 1 M KOH. Meanwhile, there was no Mo, and the NiFe-LDH needed 233 mV to attain to 10 mA cm−2. Compared to the NiFe-LDH without Mo, the NiFeMo-LDH nanosheet arrays exhibited enhanced activities with 17.1 mV/dec less Tafel in OER. The good performance of the electrocatalyst is ascribed to the special nanosheet arrays and the heterostructure of the Ni-Fe-Mo system. These features help to increase the active surface, enhancing the efficient charge transfer and the reactive activity in OER.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Biomaterials Science
·
2025
·
IF 5.7
Xinyu Wang,Qingbin He,Lining Wang,Chengzhilin Li,Wenyu Zhang,Zhonghou Rong,Qingqing Yin,Yingchun Zhao
Sepsis, an inflammatory disease caused by bacterial infection, has become a global public health crisis. Excessive reactive oxygen species (ROS) in sepsis patients act as the primary trigger for activating intracellular immune pathways, ultimately leading to multiple organ dysfunction syndrome. The overexpression of acidic metabolites and ROS, characteristic of the infected microenvironment, significantly impedes sepsis treatment. Cyclic GMP-AMP synthase (cGAS), a cytosolic DNA sensor, plays a key role in inflammatory diseases. The detrimental effects of STING in sepsis have been well documented. Here, we developed a pH-responsive nanotherapy platform (DMSNM@C-178/PAA) that combines ROS scavenging with cGAS-STING pathway inhibition for anti-inflammatory therapy. This nanoparticle is selectively released in the infected microenvironment, where reduced molybdenum-based polyoxometalates (Mo-POM) efficiently neutralize toxic ROS in vivo, while C-178 selectively inhibits the cGAS-STING pathway, thereby attenuating the inflammatory response and preventing organ deterioration. In vitro and in vivo studies demonstrate that DMSNM@C-178/PAA treats sepsis by eliminating excess ROS and modulating autoimmune dysfunction via the cGAS-STING pathway, providing a novel therapeutic strategy for sepsis management.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-11
·
IF 14.7
He Lin,Li Menggang,Qiu Longyu,Geng Shuo,Liu Yequn,Tian Fenyang,Luo Mingchuan,Liu Hu,Yu Yongsheng,Yang Weiwei,Guo Shaojun
The precise structural integration of single-atom and high-entropy-alloy features for energy electrocatalysis is highly appealing for energy conversion, yet remains a grand challenge. Herein, we report a class of single-atom Mo-tailored PdPtNiCuZn high-entropy-alloy nanosheets with dilute Pt-Pt ensembles and intrinsic tensile strain (Mo 1 -PdPtNiCuZn) as efficient electrocatalysts for enhancing the methanol oxidation reaction catalysis. The as-made Mo 1 -PdPtNiCuZn delivers an extraordinary mass activity of 24.55 A mg Pt −1 and 11.62 A mg Pd+Pt −1 , along with impressive long-term durability. The planted oxophilic Mo single atoms as promoters modify the electronic structure of isolated Pt sites in the high-entropy-alloy host, suppressing the formation of CO adsorbates and steering the reaction towards the formate pathway. Meanwhile, Mo promoters and tensile strain synergistically optimize the adsorption behaviour of intermediates to achieve a more energetically favourable pathway and minimize the methanol oxidation reaction barrier. This work advances the design of atomically precise catalytic sites by creating a new paradigm of single atom-tailored high-entropy alloys, opening an encouraging pathway to the design of CO-tolerance electrocatalysts.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Sensors
·
2024
·
IF 8.2
Shuang Cao,Zhao Song,Yu Bing,Xiaoyi Xu,Tingting Zhou,Tong Zhang
The development of a highly selective and trace-level gas sensing platform for detecting hydrogen sulfide (H2S) remains a formidable challenge. To solve this problem, Co–Mo multimetal oxide semiconductors are rationally tailored by employing metal organic frameworks (MOFs) as self-sacrificial templates. The MOF-derived Co3O4/β-CoMoO4 based gas sensors displays high sensitivity (Rg/Ra = 22) to 10 ppm of H2S and ultralow limit of detection (10 ppb H2S). The formation of p-p heterojunction and multivalence states of Mo play a crucial role in electron transfer and oxygen adsorption. A sensor array constructed from four Co3O4/β-CoMoO4 materials with different Co/Mo ratios demonstrates a superior selective discrimination of H2S from other VOCs and malodorous gases by principal component analysis (PCA). Besides, a H2S gas sensing and alarming platform was designed for monitoring the environment contaminated with H2S. This finding provides a feasible approach for the discovery of highly efficient gas sensors to monitor environmental H2S concentration.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Xiaoqin Sun,Xuejiao Feng,Yuan Dang,Sining Yun
Sulfite is deemed as a promising precursor to produce highly reactive species for contaminants remediation. Herein, the urchin-like Ni-Fe-Mo sulfide (NiFeMoS x ) was anchored in-situ on nickel foam as a cathode to activate CaSO 3 for efficient degradation of tetracycline (TC) under natural condition. The degradation efficiency reached 92.7% within 60 min, which was about 1.81 times higher than that of the electro-Fenton process based on NiFeMoS x . The beneficial performance came from the synergistic activation of CaSO 3 by simultaneous rapid redox cycles of Fe(II)/Fe(III) and Ni(II)/Ni(III) on the NiFeMoS x cathode. Specifically, the primary intermediates Fe(II)-HSO 3 - and Ni(II)-SO 3 2- triggered a series of radical chain reactions, accompanied the reduction of Ni(III)/Fe(III) by electrochemistry and electron donor of Mo(IV) and S 2- on the surface of the catalyst. The regeneration of the Fe(II)/Ni(II) was quickly realized and subsequently triggered the chain reactions, which would accelerate the formation rate of reactive species, such as SO 4 ∙ − , ·OH, O 2 ∙ − and 1 O 2 , of which 1 O 2 and O 2 •- played important roles on degradation TC. This work provides a promising application for the efficient removal of persistent organic pollutants by metal sulfide activated sulfite.
✓ 已验证
产品关联
DOI
高影响因子
ACS Nano
·
2025
·
IF 16
Hongfei Su,Jiancheng Sun,Xiao He,Zhiyong Zhang,Peng Xu,Zhouyan Chang,Qiang Wang,Wenyan Yin,Yuliang Zhao
Addressing the stability–activity imbalance of natural enzyme–nanozyme self-cascade catalysis for tumor-specific therapy while inhibiting tumor metastasis via multiple killing mechanisms remains a challenge. Herein, we constructed a tumor microenvironment (TME)-responsive mannose-modified MoS2–tannic acid (TA)–Fe–glucose oxidase (GOx) nanoreactor (MTFGM) via a spatial confinement strategy relying on metal–polyphenol coordination and electrostatic interactions for addressing this issue. GOx was confined on MoS2 via hydrogen bonds and π–π stacking. TA’s polyphenol network and mannose’s shielding effect enhanced GOx stability by preventing off-target catalysis, while TA–Fe on MoS2 boosted peroxidase (POD)-like catalytic activity by facilitating Fe3+/Fe2+ electron transfer for cocatalysis. In the TME, GOx depleted glucose to self-supply H2O2 and gluconic acid, which activated the POD-like activity of MTFGM to decompose H2O2 into toxic hydroxyl radicals (•OH) with a maximum reaction rate 4-fold higher and turnover number 170-fold higher than pristine MoS2. Simultaneously, MoS2–TA–Fe’s glutathione peroxidase-like activity plus H2Sn production continuously consumed glutathione (GSH) to break tumor antioxidant defense. This cascade synergistically induced four tumor-killing mechanisms: GOx-mediated metabolic starvation, •OH-triggered apoptosis, GSH depletion-driven ferroptosis, and cystine accumulation/H2Sn-induced disulfidptosis collectively disrupt tumor redox homeostasis and inhibit metastasis. Our work clarifies the structure–activity relationship of confinement-based cascade nanoreactors and provides a TME-responsive multiple cell death paradigm for tumor-specific therapy.
研究领域:
纳米医学
·
癌症治疗
·
生物无机化学
·
酶模拟
·
活性氧生物学
·
靶向药物递送
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Bingchen Li,Zexiong Cui,Yufeng Tao,Jin Xiong,Jinbo Gao,Lihua Liu,Shiwei Song,Pengfei Tian
The slow kinetics of the cathodic hydrogen evolution reaction (HER) present a significant obstacle for alkaline water electrolysis. Consequently, developing non-precious metal HER catalysts with high activity and stability remains a challenge. This study reports a heterostructure catalyst composed of Mo-doped amorphous Ni(OH) 2 nanosheets modified Fe 3 O 4 crystal nanoparticles (Mo-NiOH@Fe 3 O 4 ). This unique structure exhibits a three-dimensional, coral-like structure, which significantly increases the electrochemically active surface area and exposes more active sites to the electrolyte. The incorporation of Mo-doped amorphous Ni(OH) 2 enriches electron density around Fe atoms, modulating their electronic state and optimizing intrinsic activity. As an alkaline hydrogen evolution catalyst, Mo-NiOH@Fe 3 O 4 requires overpotentials of only 23.7 and 140.6 mV to achieve 10 and 100 mA cm −2 , respectively, demonstrating exceptional catalytic activity. Furthermore, it shows negligible performance degradation at 100 mA cm −2 and maintains stability for over 120 h. This work demonstrates that a heterostructure strategy, integrating Mo-doped amorphous Ni(OH) 2 with Fe 3 O 4 , provides a reasonable route for developing low-cost, high-performance HER catalysts.
研究领域:
电化学
·
材料科学
·
能源催化
·
纳米材料
·
氢气制备
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
·
2025
·
IF 7
Zhen Li,Xianhui Wang,Yan Liang,Jituo Liu
To achieve the optimal trade-off among strength, toughness and electrical conductivity, the CNTs-Mo/Cu composites with different architectural structures were fabricated by the combination of wet mixing, ball milling, spark plasma sintering (SPS) and hot rolling. The microstructure, mechanical properties and electrical conductivity of the CNTs-Mo/Cu composites were investigated, and the strengthening and toughening mechanisms were also explored based on the experimental results along with finite element simulation and first-principles. It is found that CNTs-Mo exhibits a dispersed distribution in the Cu matrix for the 0.05 wt%CNTs-Mo/Cu composite, whereas a discontinuous network structure occurs in the 0.10 wt%CNTs-Mo/Cu composite. At 0.15 wt%CNTs-Mo, the complete continuous network architecture presents in the 0.15 wt%CNTs-Mo/Cu composite. Moreover, the Mo 2 C modified on the surface of CNTs forms a semi-coherent interface with Cu, which facilitates the enhancement on the interfacial bonding between CNTs and Cu. The 0.15 wt%CNTs-Mo/Cu composite with continuous network structure displays the maximum tensile strength of 455.1 MPa, the largest elongation of 39.1 % and the optimum fracture toughness of 22.4 MPa m 1/2 , while an excellent electrical conductivity of 93.2 %IACS can also be achieved simultaneously. Furthermore, the finite element simulations reveals that the network structure suppresses stress concentration and hinders crack propagation, thereby promoting load transfer. The first-principles calculation demonstrates that Cu-Mo 2 C and Mo 2 C-CNT heterostructures display the higher absolute value of binding energy and more obvious charge transfer than the CNT-Cu heterostructure, suggesting that the incorporation of Mo 2 C plays a crucial role in improving the interfacial stability and interfacial bonding strength of CNTs-Cu. The simultaneous improvement on strength and toughness of the 0.15 wt%CNTs-Mo/Cu composite can be attributed to strong interfacial bonding, effective load transfer, as well as crack deflection and bridging effects stemmed from the CNTs.
研究领域:
材料科学
·
纳米复合材料
·
机械工程
·
导电性
·
计算材料科学
✓ 已验证
DOI
高影响因子
Inorganic Chemistry Frontiers
·
2025
·
IF 6.4
Yujie Wang,Ziqi Zhong,Guowu Zhan,Jingran Xiao
Molybdenum (Mo) doping has been recognized as an effective strategy to enhance the low-bias performance of hematite (Fe2O3) photoanodes in photoelectrochemical (PEC) water splitting. This study develops a mild hydrothermal strategy for incorporating Mo into Fe2O3 photoanodes, forming a Mo–O–Fe surface layer while avoiding the morphological degradation associated with conventional calcination. Although this modification enhances bulk charge separation and surface charge injection, the resulting Mo–O–Fe interface suppresses the functionality of directly deposited FeNi oxyhydroxide cocatalysts, yielding limited performance gains. To overcome this limitation, a hydroxyethylidene diphosphonic acid (HEDP) interlayer is introduced, which enables synergistic cooperation among the three components. It is plausible that HEDP acts as a hole-transfer mediator, shuttling holes from Mo–O–Fe surface states to the FeNi cocatalyst. The optimized FeNi/HEDP/Mo-Fe2O3 photoanode achieves a notable photocurrent density of 1.26 mA cm−2 at a low bias of 0.90 V vs. RHE and an onset potential of 0.59 V vs. RHE. The synergistic combination of mild hydrothermal doping and molecular interfacial engineering presented here provides a conceptual blueprint for the rational design of photoelectrodes, highlighting the critical need to manage interfacial charge dynamics to achieve high efficiency in the low-bias regime.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2026
·
IF 6.7
Pengcheng Wang,Jiaxin Li,Xuanpan Xu,Zhanhong Peng,Yihui Song,Yuan Yao,Ting Zhu,Weibin Zhang,Qianjin Wang,Hong-En Wang,Chen Qing
Developing efficient electrocatalysts for the alkaline hydrogen evolution reaction (HER) remains challenging due to sluggish water dissociation and suboptimal hydrogen adsorption. Herein, we report an in-situ precursor-leaching-induced strategy for fabricating Co x Ni 1-x (OH) 2 solid solution nanorod arrays via complete Mo leaching from hydrothermally grown Co x Ni 1-x MoO 4 ·H 2 O on Ni-Co foam. This transformation preserves the one-dimensional architecture, yielding a Mo-free, binder-free electrode with exceptional HER activity, characterized by overpotentials of 38 mV and 208 mV at 10 and 50 mA cm -2 , respectively, and stability over 300 h at 100 mA cm -2 . Experimental and theoretical analyses reveal that adjacent Ni and Co sites synergistically optimize the adsorption thermodynamics of hydrogen intermediates and promote interfacial charge transfer, while Mo is fully removed as a sacrificial component that triggers the in-situ reconstruction into a Co–Ni hydroxide solid solution. This work provides a practical route to high-performance alkaline HER catalysts enabled by atomic-level Ni–Co electronic synergy.
✓ 已验证
产品关联
DOI
高影响因子
Energy & Environmental Materials
·
2026
·
IF 13.8
Eunchae Oh,Jaewon Jang,Yoon Kyeung Lee,Junghoon Yang,Byung-Joo Kim,Jungpil Kim
The direct conversion of CO 2 into high-quality carbon nanotubes (CNTs) remains a formidable challenge, primarily due to the oxidation of metal catalyst by the oxidative nature of CO 2 . To overcome this limitation, a tandem catalytic system was implemented, in which CO 2 was converted to produce CH 4 on Ni catalysts in the primary reactor, and the CNT was synthesized from CH 4 on an Fe catalyst in the secondary reactor. Nevertheless, unreacted CO 2 was introduced into the secondary reactor, where the Fe catalysts were oxidized and thus failed to produce any solid carbon. To prevent the oxidation of Fe catalysts, a bimetallic Fe–Mo catalyst was employed instead of pure Fe. Mo was partially converted to Mo 2 C by reacting with unreacted CO 2 , which effectively suppressed the oxidation of Fe, thereby stabilizing the active Fe phase. This transformation was further corroborated by XPS analysis, where the Mo 3d spectra exhibited an increased Mo 2+ peak intensity, whereas the Fe 2p spectra showed a stronger metallic Fe signal, confirming that Mo incorporation inhibited Fe oxidation. However, excessive Mo loading resulted in the formation of multi-walled CNTs instead of single-walled CNTs, as evidenced by the reduced selectivity toward radial breathing modes in the Raman spectra and the broader diameter distribution observed in TEM measurements. These findings underscore the critical role of Mo in preserving Fe activity under oxidizing conditions and highlight the importance of optimizing its content, as an appropriate Mo level enables the selective synthesis of high-quality single-walled CNTs from CO 2 via a dual-step tandem process.
✓ 已验证
产品关联
DOI
高影响因子
TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA
·
2022
·
IF 3.752
Zhuang-zhi WU,Na ZHAO,Yao LU,Hai-lang LIU,Bo-hua DUAN,Xin-li LIU,De-zhi WANG
The morphology and size of second phase greatly influence the strengthening effect on oxidation dispersion strengthened Mo alloys. In this work, a novel nanostructuring strategy is adopted to modify the second phase of Y 2 O 3 , and the corresponding effects of particle shape and size on mechanical properties of sintered Mo-Y 2 O 3 alloys were investigated. It is found that spherical particles with sizes below 200 nm are preferred due to the dominant intragranular distribution of second phases associated with better strengthening effect originating from dislocation pinning. With smaller particle size of Y 2 O 3 nanospheres (105 nm), the tensile strength of corresponding Mo alloy is enhanced by about 43.8%, much higher than that (8.3%) reinforced by second phase nanospheres with larger particle size (322 nm). Meanwhile, with similar particle size (around 100 nm), the spherical shape exhibits better strengthening effect than the one reinforced by one-dimensional rod-like second phase.
研究领域:
材料科学
·
冶金学
·
机械工程
·
纳米材料
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）