ACS Food Science & Technology
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2026
·
IF 3
Zi-Jia Ji,Lei-Lei Wang,Xiao-Li Wang,Lu Liu,Xia Wang,Ru-Song Zhao
Aflatoxins (AFTs) pose a significant threat to the harvesting and storage of food crops and have adverse effects on human health. Combining metal–organic framework (MOF) materials and surface imprinting technology has been recognized as an effective strategy to fabricate selective adsorbents for the extraction of AFTs. In this study, molecularly imprinted MOFs (MI-d-UiO-66-NH2) were synthesized via surface imprinting. MI-d-UiO-66-NH2 exhibited selectivity toward AFTs owing to its abundant imprinted cavities and functional groups. The developed analytical method for AFTs, coupled with high-performance liquid chromatography tandem mass spectrometry, achieved low detection limits ranging from 0.001 to 0.150 ng mL–1. The recoveries of AFTs in four cereal samples spiked at three different concentrations (2.0, 5.0, and 10.0 μg kg–1) were 81.3% to 96.3%, with relative standard deviations of ≤9.5%. This study offers an effective approach for the accurate determination of trace AFTs in complex food matrices.
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MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Biyao Zhao,Xiaoyu Wu,Xuwen Ye,Fangyi Jia,Yuanyuan Wang
The determination of acetylcholinesterase (AChE) activity and organophosphorus pesticides plays a critical role in disease diagnosis, drug screening, and food safety monitoring. In this study, we report a multifunctional UiO-66@MnO 2 nanocomposite that integrates both oxidase-mimicking activity and intrinsic fluorescence, enabling dual-mode colorimetric and fluorescence sensing. MnO 2 nanosheets anchored on the surface of the UiO-66 not only catalyze the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) but also efficiently quenched the fluorescence of UiO-66 via Förster resonance energy transfer. Upon the addition of acetylthiocholine and AChE, the enzymatic generated thiocholine reduces MnO 2 , resulting in disassembly of the nanocomposite. This triggers a “turn-off” colorimetric signal and a “turn-on” fluorescence response, enabling sensitive detection of AChE with detection limits as low as 0.076 mU/mL (colorimetric) and 3.8 mU/mL (fluorescence). Furthermore, taking advantage of the inhibitory effect of organophosphorus pesticides on AChE activity, the proposed platform was further successfully extended to detect dipterex, achieving detection limits of 0.032 μM (colorimetric) and 1.1 μM (fluorescence). Moreover, the dual-mode nanozyme sensor was successfully validated in complex biochemical samples, highlighting its considerable potential for applications in bioanalysis, food safety monitoring, and environmental surveillance.
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JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2026
·
IF 4
Rui Chu,Wenhui Li,Jintian Wang,Xiaoyang Li,Tianying Lu
BACKGROUND Patulin (PAT) is a mycotoxin commonly found in apple products, which poses significant health risks and is challenging to remove using conventional methods. This study employed a ligand functionalization strategy to precisely modulate the microenvironment of metal–organic frameworks and investigate its impact on PAT adsorption performance. RESULTS A series of functionalized UiO-66 nanomaterials (UiO-66, UiO-66-NH 2 , and UiO-66-SH) were synthesized via solvothermal method using zirconium as the metal node and terephthalic acid derivatives as organic linkers. Comprehensive characterization confirmed the successful incorporation of the corresponding functional groups and the conserved crystalline structure of the UiO-66. Screening of their adsorption capabilities revealed a dramatic dependence on the surface chemistry, with UiO-66-SH exhibiting superior PAT adsorption performance and achieving complete removal under optimized conditions. Adsorption kinetics and isotherm studies were conducted. The results demonstrated that the adsorption process of UiO-66-SH toward PAT followed a pseudo-second-order kinetics model and the Langmuir adsorption isotherm, indicative of chemisorption-driven monolayer adsorption. The maximum adsorption capacity was determined to be 18.209 μg mg −1 . Mechanistic investigations confirmed that the thiol groups on UiO-66-SH chemically interacted with PAT via a Michael addition reaction, thereby achieving efficient adsorption and removal of PAT. In practical application, UiO-66-SH effectively removed PAT from spiked apple juice while maintaining the key quality parameters of apple juice. CONCLUSION Our study demonstrates that ligand-induced microenvironment modulation renders UiO-66-SH a highly efficient and selective adsorbent for PAT decontamination, offering a promising strategy for enhancing the safety of apple products. © 2026 Society of Chemical Industry.
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CHINESE JOURNAL OF CATALYSIS
·
2026
·
IF 17.2
Yaowen Wei,Jianwei Wang,Hao Guo,Tao Ban,Yufeng Yue,Di Hu,Haibao Huang
The direct conversion of methane (CH 4 ) into higher-value C2 products is essential for the green and efficient conversion of clean energy. However, this conversion process faces significant challenges due to the difficulty in activating methane's C–H bonds and the complexity of controlling C–C coupling reactions. Herein, we design and construct the unsaturated metal Zr 4+ site by introducing ligand defects in UiO-66 through treatment with trifluoroacetic acid (TFA), which enables the direct oxidation of methane to acetic acid using H 2 O 2 under mild conditions. Remarkably, a volcano-shaped correlation was observed between the degree of ligand defects in UiO-66 and acetic acid selectivity. Under optimal conditions (150 °C), the catalyst achieved an outstanding acetic acid selectivity of 84% with a high yield of 1691 μmol·g cat. –1 . Notably, the catalyst exhibited exceptional stability, maintaining its performance over at least five consecutive reaction cycles. Through TFA modulation, the d -band center of the Zr 3 d orbital in Zr 4+ sites exposed by UiO-66 shifts upward. This promotes the decomposition of H 2 O 2 , thereby facilitating the formation and stabilization of highly reactive Zr–OH species, which enhances the activation of C–H bonds in CH 4 . The resulting *CH 3 species is further oxidized by *OH species into *COOH species, which undergo stable C–C coupling at exposed Zr 4+ sites to produce acetic acid. This work provides novel insights into the design of highly efficient catalysts for the direct conversion of methane into C2 oxygenates compounds under mild conditions.
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Journal of Energy Storage
·
2026
·
IF 10.7
Shang Wu,Qiyue Tong,Huize Zhang,Zhenyang Yu,Chenxu Zhu,Qiong Su,Hong Zhang,Guihua Li,Xiaojun Yang,Juzhen Kang,Quanlu Yang
NH 2 -UIO-66 has been regarded as a promising porous material owing to its high specific surface area and structural stability, although its limited conductivity restricts its application in supercapacitors. In this work, a NiCo 2 S 4 /NH 2 -UIO-66 nanoflower composite (NCS/NU) was synthesized via a vulcanization process with thioacetamide. Electrochemical measurements conducted in a three-electrode system revealed that the composite delivered a specific capacitance of 172.4 mAh g −1 at 1 A g −1 and maintained 82.1% of its initial capacitance after 5000 cycles at 5 A g −1 . Morphological characterization indicated that the nanoflower architecture was largely preserved after sulfurization. The in-situ formed NiCo 2 S 4 contributed to enhanced pseudocapacitance and induced surface wrinkling of the petals, which helped stabilize the composite structure supported by NH 2 -UIO-66. For the anode, S and N co-doped three-dimensional porous carbon (SNC) was prepared via a sol-gel method followed by stepwise high-temperature carbonization using ammonium persulfate as the activator. A hybrid supercapacitor was subsequently assembled with the NCS/NU as the positive electrode and SNC-700 as the negative electrode. The device delivered an energy density of 28.8 Wh kg −1 and retained 74.1% of its initial capacitance after 5000 charge-discharge cycles.
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MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 5
·306
·
IF 5.4
Zhu Yuchuan,Li Junhong,Yang Ruoxi,Bao Mingqiu,Hao Yakai,Chen Huijin,Yue Ruirui,Shu Jinbing,Duan Xuemin
A ternary nanocomposite, PEDOT:PSS/UiO-66-Cl@Ru, was successfully synthesized via a one-pot hydrothermal strategy for the ultrasensitive electrochemical detection of amaranth (AM) and Allura Red (AR). The conceptual advance of this work lies in the synergistic integration of halogen-induced intrinsic electroactivity, maximal atomic utilization of single-atom Ru, and the conductive bridging effect of PEDOT:PSS. This ternary design effectively overcomes the conductivity bottleneck of MOFs while delivering exceptional catalytic site density and enhanced interfacial stability. The resulting PEDOT:PSS/UiO-66-Cl@Ru platform delivered remarkable analytical performance, featuring wide linear ranges of 0.05–140 µM for AM and 0.07–50 µM for AR. The low limits of detection were 16.6 nM and 23.3 nM, with high sensitivities of 0.179 µA µM⁻¹ cm⁻² and 0.247 µA µM⁻¹ cm⁻² for AM and AR, respectively. Furthermore, the proposed sensor demonstrated excellent selectivity, reproducibility, and stability. Finally, the successful application of PEDOT:PSS/UiO-66-Cl@Ru in detecting AM and AR within beverage samples validates its practical utility for on-site food safety screening.
Section
Graphical abstract
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SENSORS AND ACTUATORS B-CHEMICAL
·
2026
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IF 8.3
Jingyi Yang,Yong Zhang,Zhiheng Ma,Jiaqiang Xu,Chenglin Sun
The development of highly selective trace ammonia (NH 3 ) detection technology based on metal-organic frameworks (MOFs) is of critical significance for the precise monitoring of ammonia in industrial and agricultural production environments. In this study, a series of UiO-66 materials doped with different metal ions (X-UiO-66, X = nickel, copper, iron, and aluminum) were synthesized. Through comparative analysis, the Ni-UiO-66 based QCM sensor exhibited superior sensing performance for trace NH 3 at room temperature: A detection limit as low as 50 ppb, high sensitivity (frequency response of 1766 Hz to 25 ppm NH 3 ), fast response/recovery times (10 s/13 s), as well as good selectivity, long-term stability, and reliable detection capability in high-humidity environments. The doping of Ni 2 + creates defects in the framework, increases the specific surface area, and provides more abundant active adsorption sites, thereby significantly enhancing the sensitivity to NH 3 . Furthermore, adsorption tests, Gaussian simulations, and in-situ infrared spectroscopy revealed a significantly optimized reversible weak chemical adsorption interaction between Ni-UiO-66 and NH 3 , which endowed the material with enhanced selectivity compared to pristine UiO-66 toward NH 3 . This work provides a reliable strategy for designing MOF-based sensing materials that combine structural stability and high activity.
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CHEMICAL ENGINEERING SCIENCE
·
2026
·
IF 5.1
Mengying Lin,Hanyue Lou,Zhaoyang Qi,Jie Chen,Changshen Ye,Ting Qiu
The development of highly active catalysts is crucial for oxidative desulfurization (ODS) to meet the growing demand for sulfur-free fuels. In this study, a defect-rich composite catalyst UiO-DAlaPW was successfully synthesized via mechanochemical grinding, wherein phosphotungstic acid (HPW) was encapsulated within a defect-engineered UiO-66 framework, utilizing D-alanine (DAla) as a bridging molecule. The synthesized catalyst, UiO-DAlaPW, significantly enhances the utilization efficiency of hydrogen peroxide (H 2 O 2 ). In the model oil ODS system, the material exhibited exceptional catalytic performance: achieving deep desulfurization at room temperature within merely 5 min under conditions of extremely low acetonitrile cosolvent usage and a low oxidant/sulfur (O/S) ratio, accompanied by remarkably high H 2 O 2 utilization efficiency. Moreover, the catalyst maintained high desulfurization efficiency even in the absence of acetonitrile. Characterization by XRD, FT-IR, TGA, and XPS confirmed the successful encapsulation of HPW within the UiO-66 framework. Mechanistic studies revealed a significant synergistic effect between UiO-66 and HPW. The effective cooperation of the two active sites, namely Zr in UiO-66 and PW, significantly enhances the catalytic performance, contributing to superior oxidative desulfurization activity.
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ANALYST
·
2022
·Vol. 147
·期 24
·5655-5662
·
IF 5.227
Ying Zhou,Ruichun Li,Guomei Zhang,Yan Zhang,Caihong Zhang,Shaomin Shuang
Metal–organic frameworks (MOFs) have emerged as interesting nanomaterials owing to their large surface area, high porosity, tunable pore architecture and easy functionalization. However, an inferior electrical conductivity hinders their application in electrochemical sensing. In this paper, gold–palladium alloy/UiO-66-NH2/graphene (AuPd/UiO-66-NH2/GN) composites were synthesized by loading alloys on the surfaces of MOFs and then attaching them to the graphene surface. The addition of metal nanoparticles and graphene enhanced the electron transfer ability of MOFs. Then, composites were used to modify a glassy carbon electrode (GCE) to construct a sensitive dopamine (DA) electrochemical sensor. The developed sensor manifested two linear relationships in lower concentration ranges and in higher concentration ranges with a 0.21 × 10−6 mol L−1 low detection limit (3σ/k) under optimal conditions. The results certified that the constructed sensor had high selectivity, excellent reproducibility and good stability, and had been used successfully for DA detection in actual human serum samples.
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Journal of Cleaner Production
·
2023
·
IF 11.1
Di Zhang,Hao Tang,Bing Zhao,Lijie Liu,Hongwei Pang,Xiangxue Wang,Shujun Yu
Radioactive uranium removal plays a key role in energy development and environmental security. Sulfide nanoscale zero-valent iron (S-NZVI) has good antioxidant capacity, dispersibility and activity to eliminate U(VI) from wastewater, but the removal efficiency is limited. To improve the reduction and adsorption capacity of S-NZVI, through treating Fe 3+ solution by nitro-functionalized UiO-66 (UiO-66-NO 2 ) with high porosity, UiO-66-NO 2 enhanced S-NZVI adsorbent (S-NZVI/UiO-66) was prepared by liquid phase reduction method. The smaller size and larger specific surface area of S-NZVI/UiO-66 were confirmed by a variety of characterization techniques. Based on the excellent surface structure and reactivity, the U(VI) removal capacity of S-NZVI/UiO-66 (895 mg g −1 ) was much better than S-NZVI (434 mg g −1 ) and UiO-66-NO 2 (267 mg g −1 ). The impacts of pH, background ion strength, coexisting ions and different water environments on adsorption were studied via macroscopic batch experiments. The results showed that S-NZVI/UiO-66 could remove U(VI) adequately in a wide pH range. The removal rate was basically not affected by the concentration of NaNO 3 , demonstrating that the adsorption process of U(VI) on S-NZVI/UiO-66 tended to inner surface complexation. From XPS technique combined with the results of batch adsorption experiments, it was clear that the elimination mechanisms of U(VI) by S-NZVI/UiO-66 were mainly the physical adsorption, electrostatic attraction and complexation of UiO-66-NO 2 , and the reduction and complexation of S-NZVI. Therefore, it is believed that S-NZVI/UiO-66 has a great potential to be an excellent adsorbent in the field of the environment remediation. Moreover, S-NZVI/UiO-66 promises to be a novel nanomaterial for solving the problem of radionuclide contamination in practical environments.
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TALANTA
·
2022
·
IF 6.556
Pengfei Zhao,Sisi Tang,Xiaodan Wu,Yu Chen,Kangling Tang,Jinli Fu,Huibin Lei,ZhaoXia Yang,Zhaohui Zhang
Development of method with micro-volume reagent usage and high selectivity for rapid determination of valuable disease-related biomarkers is of great importance for disease surveillance. Herein, a novel ratiometric fluorescence capillary imprinted sensor was developed for highly selective fluorescence determination of sialic acid (SA) based on luminescent metal-organic framework (UiO-66-NH 2 ). In this strategy, the imprinted pre-polymer with double emissions was sucked into the capillary to grow imprinted layer on the inner wall of the capillary. In presence of SA, the blue fluorescence (440 nm) served as fluorescence response signal was quenched due to the electron transfer mechanism between metal organic framework and SA while the red fluorescence (655 nm) served as the reference signal was remained. Within SA concentration linear range of 1.0 × 10 −7 –3.0 × 10 −4 M, the ratiometric fluorescence capillary imprinted sensor was applied to detect SA in human serum and saliva samples successfully with a detection limit of 2.5 × 10 −8 M. A sensitive and selective fluorescence method with micro-volume sample consumption (15 μl) for determination of SA in practical samples was established.
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CARBOHYDRATE POLYMERS
·
2022
·
IF 10.723
Zhi Chen,Zhi-Bo Zhang,Jun Zeng,Zhi-Jie Zhang,Shan Ma,Cong-Ming Tang,Jun-Qiang Xu
In this work, a polyethyleneimine-modified chitosan/Ce-UIO-66 composite hydrogel (PEI-CS/Ce-UIO-66) was prepared using the ex-situ blend method. The synthesized composite hydrogel was characterized by SEM, EDS , XRD, FTIR, BET, XPS, and TG techniques, while the zeta potential was recorded for sample analysis. The adsorbent performance was studied by conducting adsorption experiments using methyl orange (MO), which showed that PEI-CS/Ce-UIO-66 exhibited excellent MO adsorption properties (900.5 ± 19.09 mg/g). The adsorption kinetics of PEI-CS/Ce-UIO-66 could be explained by the pseudo-second-order kinetic model , and its isothermal adsorption followed the Langmuir model. Thermodynamics showed that the adsorption was spontaneous and exothermic at low temperatures. MO could interact with PEI-CS/Ce-UIO-66 via electrostatic interaction , π–π stacking, and hydrogen bonding . The results indicated that the PEI-CS/Ce-UIO-66 composite hydrogel could potentially be used for the adsorption of anionic dyes.
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