MICROCHIMICA ACTA
·
2018
·Vol. 185
·期 4
·1-8
·
IF 5.705
Shao Hong,Xu Dan,Ding Yadan,Hong Xia,Liu Yichun
The authors describe an “off-on” colorimetric and fluorometric assay for the determination of Cu(II). It is based on the use of upconversion nanoparticles (UCNPs) of type NaYF 4 :Yb(III),Er(III) that were functionalized with branched polyethylenimine (BPEI). A color change from colorless to blue occurs within 2 s after addition of Cu(II) to a solution of the modified UCNPs. The color change can be visually detected at Cu(II) concentrations down to 80 μM. The upconversion fluorescence of the modified UCNPs, measured at excitation wavelength of 980 nm, is reduced due to the predominant inner filter effect caused by the formation of the BPEI-Cu(II) complex. Normalized fluorescence intensity drops linearly in the 50 nM to 10 μM Cu(II) concentration range, and the fluorometric detection limit is 45 nM. Both the color and the fluorescence are recovered on addition of EDTA. Excellent selectivity over other metal ions and anions is achieved.
Upconversion nanoparticles of type NaYF4:Yb,Er were functionalized with branched polyethylenimine (UCNP/BPEI) and used in an “off-on” colorimetric and fluorometric assay for Cu(II). The upconversion fluorescence is selectively quenched on addition of Cu(II), and this is accompanied by a rapid colorless-to-blue color switch. The colorimetric changes and quenched fluorescence can be reversed by adding EDTA.
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PubMed
高影响因子
LANGMUIR
·
2014
·
IF 4.384
Hongqi Chen,Yingying Guan,Shaozhen Wang,Yuan Ji,Mengqi Gong,Lun Wang
A homogeneous immunoassay for the sensitive and selective determination of trace amounts of α-fetoprotein (AFP, a cancer marker) by detection in the near-infrared (NIR) region based on luminescence energy transfer (LET) from NaYF4:Yb,Tm/NaGdF4 core–shell upconverting nanoparticles to gold nanorods (GNRs) is presented. The carboxyl-functionalized NaYF4:Yb,Tm/NaGdF4 core–shell upconverting nanoparticles (UCNPs) were excited by a 980 nm continuous wavelength laser, and its emission peak appeared at a near-infrared wavelength (∼804 nm). The carboxyl-functionalized upconverting nanoparticles were conjugated with the anti-AFP (Ab1) and acted as donor. GNRs with a high absorption band around 790 nm, which was overlapped the UCNPs emission, were synthesized and acted as the acceptor. The donor (negatively charged) interacted with the acceptor (positively charged) via electrostatic interactions to bring them into close proximity. LET could occur, producing a quenching phenomenon. When the AFP antigens were added into the system, the binding affinity between AFP and Ab1 was stronger than the electrostatic interactions, which released the energy acceptors from the energy donors, interrupting luminescence energy transfer, and therefore, the luminescence was recovered. On the basis of the restored luminescence, a turn-on optical immunosening system was developed. Under the optimal conditions, the linear range of detection was from 0.18 to 11.44 ng/mL for AFP (R = 0.99), with a detection limit as low as 0.16 ng/mL. The proposed method has also been used to monitor AFP in human serum samples. Therefore, further study based on the NaYF4:Yb,Tm/NaGdF4 core–shell nanoparticles-GNRs construction may open the way for a new class of NIR-LET biosensors with wide applications.
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高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Zhongfei Shang,Meimei Wang,Honghong Li,Jiahao Dong,Luyan Yang,Xincun Dou,Baiyi Zu
The exploration of efficient hazardous chemical sensing technology is of great importance to protect the environment and maintain public security. Here, a design strategy of a trimode upconversion nanoprobe was developed for H2O2 detection through establishing the inner filter effect (IFE) between the anthracene-based probes and the NaYF4:Yb/Tm/Er upconversion nanoparticles (UCNPs). The trimode nanoprobe exhibits superior H2O2 detection performance, including a low limit of detection (LOD) of 152 nM, fast response (<3 s), outstanding selectivity, and robust anti-interference ability even in the presence of 15 common interferents. Furthermore, the practical utility of this design is conclusively demonstrated through a sensing chip capable of accurately and selectively identifying H2O2 even in the presence of more than 7 types of coexisting multicolor interferents. This sensing strategy, characterized by its strong anti-interference capability even when facing extremely complex real-world samples, is expected to establish a promising framework for ultra-accurate detection of hazardous substances.
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2026
·Vol. 37
·期 14
·1082
·
IF 3.2
Pang Bo,Cui Yanqun,Yin Jing
As a fundamental element in integrated photonic systems, the functionality of polymer-based waveguide amplifiers is primarily determined by the optical properties of the active material. More precisely, the amplification bandwidth establishes the working spectral region of the photonic circuit. Consequently, developing gain media that feature both broad bandwidth and high gain has emerged as a critical challenge in the field. The performance of this gain medium is fundamentally determined by rare-earth-ion-doped crystals, as the emission spectrum of these crystals ultimately dictates the achievable gain bandwidth. In this study, Y 2 O 3 : Yb, Er, Ce crystals with emission peaks covering the entire S + C + L band were prepared. In Y₂O₃ crystals with low crystal field symmetry, the 4 I₁₃/₂ and 4 I₁₅/₂ levels of Er 3+ ions were observed to undergo severe splitting, which in turn allows for effective broadening of the operational bandwidth. Fluorescence analysis reveals that the broadband emission from Er 3+ ions stems from the pronounced energy level splitting caused by the crystal field effect. When irradiated with a 980 nm laser, the emitted peak coverage from these Y 2 O 3 : Yb, Er, Ce crystals spans the complete S + C + L spectral range, demonstrating broadband optical amplification properties. Incorporation of Ce 3+ substantially improved the emission strength within these crystals across the S + C + L spectral region. Given their remarkable broadband luminescence characteristics across the S + C + L spectral range, Y 2 O 3 : Yb, Er, Ce materials represent promising candidates for gain media in next-generation polymer-based optical amplifiers.
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高影响因子
Journal of Materials Chemistry C
·
2025
·
IF 5.1
Jin Liu,Boying Wang,Shuxin Li,Yao Wang,Jun Li,Yan Zhang,Christopher D. Snow,Matt J. Kipper,Soo Wohn Lee,Laurence A. Belfiore,Jianguo Tang
Advanced data storage and anti-counterfeiting technologies are critical in addressing modern information safety. In this work, novel nanocomposites of Eu3+, Tb3+, Zn2+ and -hyaluronan for down-conversion and NaGdF4:Yb,Er nanoparticles for up-conversion have been synthesized and applied for innovative anticounterfeiting luminescent inks. These inks exhibit excellent fluorescence under dual UV or NIR excitation, and sensitive quenching in response to some ions or compounds, enabling multi-level data encoding, reversible Cu2+ detection, and dynamic information concealment. Utilizing electrohydrodynamic (EHD) printing, we achieved precise patterns with line widths of approximately 20–50 μm, facilitating dynamic information concealment and secure data storage. The printed patterns, invisible under natural light, displayed distinct and bright fluorescence when stimulated by UV and NIR light, offering orthogonal readout capabilities for secure information retrieval. Additionally, the luminescent inks demonstrated remarkable sensitivity to Cu2+ ions, with fluorescence quenching efficiency reaching 85.3% at a Cu2+ concentration of 100 μg mL−1. The quenching process was reversible upon introducing ethylenediaminetetraacetic acid (EDTA), enabling up to three cycles of fluorescence recovery and suppression with minor degradation (<15%) in intensity after repeated use. The high-resolution EHD printing technology combined with excellent sensing performance, such as a detection limit of 1.2 μg mL−1 for Cu2+, enables a promising strategy for advancing intelligent information systems and hazardous ion detection. This work offers a versatile solution for secure information coding, anti-counterfeiting, and environmental sensing, providing a significant advancement in multifunctional luminescent materials, especially for smart quadruplicate information coding and hazard sensing, with dual UV/IR excitation.
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高影响因子
PLoS One
·
2013
·Vol. 8
·期 8
·e71071
·
IF 3.73
Bo-xin Zhao,Ya-bin Sun,Sheng-qi Wang,Lian Duan,Qi-lu Huo,Fei Ren,Guo-feng Li
The expression and function of P-glycoprotein (P-gp) is associated with the phenotype of multi-drug resistance (MDR), leading chemotherapy failure of patients suffered with cancer. Grape seed procyanidin(GSP) is a natural polyphenol supplement with anti-inflammatory effect. Present study assessed a new use of GSP on the MDR reversal activity and its possible molecular mechanisms in MDR1-overpressing paclitaxel resistant ovarian cancer cells. Our results showed GSP significantly enhanced the cytotoxicity of paclitaxel and adriamycin in paclitaxel resistant A2780/T cells but its parental A2780 cells. Furthermore, GSP strongly inhibited P-gp expression by blocking MDR1 gene transcription, as well as, increased the intracellular accumulation of the P-gp substrate rhodamine-123 in A2780/T cells. Nuclear factor-κB(NF-κB) activity, IκB degradation level and NF-κB/p65 nuclear translocation induced by lipopolysaccharide (LPS) and receptor activator for nuclear factor-κB ligand (RANKL) were markedly inhibited by pre-treatment with GSP. Meanwhile, GSP inhibited MAPK/ERK pathway by decreasing the phosphorylation of ERK1/2, resulting in reduced the Y-box binding protein 1 (YB-1) activation with blocking its nuclear translocation. Moreover, the up-regulation of P-gp expression, the activation of AKT/NF-κB and MAPK/ERK pathway induced by LPS was attenuated by GSP administration. Compared with PDTC and U1026, inhibitor of NF-κB and MAPK/ERK respectively, GSP showed the same tendency of down-regulating NF-κB and MAPK/ERK mediated YB-1 activities. Thus, GSP reverses P-gp associated MDR by inhibiting the function and expression of P-gp through down-regulation of NF-κB activity and MAPK/ERK pathway mediated YB-1 nuclear translocation, offering insight into the mechanism of reversing MDR by natural polyphenol supplement compounds. GSP could be a new potential MDR reversal agent used for combination therapy with chemotherapeutics in clinic.
研究领域:
肿瘤学
·
药理学
·
分子生物学
·
细胞生物学
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PubMed
高影响因子
MICROCHIMICA ACTA
·
2018
·Vol. 185
·期 10
·1-10
·
IF 5.705
Xu Sai,Yu Yang,Gao Yuefeng,Zhang Yanqiu,Li Xiangping,Zhang Jinsu,Wang Yunfeng,Chen Baojiu
Accurate detection of temperature and oxygen concentration at the cellular level is important in tumor diagnosis. Multifunctional nanocomposites are described that consist of upconversion luminescent nanoparticles capped with mesoporous silica and loaded with an oxygen-sensitive luminescent ruthenium complex. The nanocomposites of type NaYF 4 :Yb,Er@NaYF 4 @mSiO 2 -Ru have two modes of operation: Its red downconversion luminescence (at excitation/emission peaks of 455/606 nm) is quenched by oxygen (O 2 ), and this is used to sense and image O 2 . The green upconversion luminescence (typically acquired at excitation/emission wavelengths of 980/525 and 544 nm), in turn, is used to measure temperature. The nanocomposites were then applied to dual mode in-vitro imaging of temperature and O 2 in hepatocellular carcinoma cells (HepG-2).
A new multifunctional nanocomposite of mesoporous silica coating NaYF 4 :Yb,Er@NaYF 4 upconversion nanopaticless loaded with ruthenium (II) complex has been designed with both green upconversion and red downconversion luminescence for temperature detection, oxygen sensing and dual mode cell imaging.
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PubMed
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2013
·Vol. 97
·期 3
·990-995
·
IF 2.107
Kuo Jiang,Songbai Liu,Yuan Li,Yaofei Li
Powders of zirconia doped with 8 mol% REO 1.5 (RE = Yb, Y, Gd, and Nd) were synthesized by using the sol–spray pyrolysis method. The effects of RE 3+ ionic radius on monoclinic (m) phase content of powders were investigated. The XRD results showed that the metastable tetragonal (t′) phase underwent a complete phase change to form m and cubic (c) phases after a heat treatment of 50–100 h at 1450°C. A cation size-dependent reduction in the m phase content of the REO 1.5 partially stabilized ZrO 2 powders was observed. The SEM–EDS analysis of the powders revealed that the RE 3+ concentrations in the c phases decreased with decreasing the RE 3+ ionic radius. These results indicate that the stabilizer concentration of the c phase can be attributed to RE 3+ ionic radii, resulting in different m phase contents. Compared to the REO 1.5 single doped ZrO 2 , the m phase contents of 8 mol% (RE 0.5 Yb 0.5 )–ZrO 2 (RE = Y, Gd, and Nd) powders were significantly reduced. The results prove that the stabilizer with a lower RE 3+ size is effective in reducing the m phase content of partially stabilized ZrO 2 after annealing at high temperatures.
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高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Mingye Ding,Xiaoyan Wang,Yinbiao Shi,Zixia Lin,Zhengtao Deng,Xiaofei Yang
Owing to their excellent photoelectric and optical properties, lead halide perovskite quantum dots (PeQDs) have attracted great attention and have broad applications in various fields. However, the shortcomings of poor stability and short-wavelength (ultraviolet/visible) excitation restrict their practical applications. Herein, to address the above issues, we report a polyacrylonitrile-based composite film containing CsPbX3 (X = Br and I) PeQDs and β-NaYF4:Yb/Ln (Ln = Tm and Er) upconversion nanoparticles (UCNPs) via an electrospinning strategy. Interestingly, all-inorganic CsPbX3 PeQDs are synthesized through an in situ growth process in polyacrylonitrile nanofibers, which provide a polymer matrix for the protection of PeQDs against decomposition under the effect of an external environment. Upon 980 nm laser irradiation, lanthanide-sensitized UC luminescence of stable CsPbX3 can be realized through radiative energy transfer from Tm3+/Er3+ ions to PeQDs. Consequently, dual-mode luminescence, including downshifting and UC with color-tunable outputs, can be observed from PeQDs under dual-wavelength excitation (UV and NIR). Benefiting from the special luminescent feathers (temperature-sensitive UC and dual-mode luminescence), the as-obtained composite nanofibers exhibit great potential in high-level anticounterfeiting and accurate noncontact thermometry.
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高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Yaochen Si,Lingfeng Li,Ruida Wang,Songting Zhang,Yingnan Cao,Hongyu Li,Shixian Zhao,Hongxia Li,Jing Feng
With the development of high power and high thrust-weight ratio aeronautics and astronautics, aircraft engines and gas turbine technology, the development of thermal barrier coating (TBCs) material is an enormous challenge, which requires both high temperature stability and resistance to molten calcium-magnesium-aluminosilicate (CMAS) corrosion. In this study, five high-entropy rare-earth tantalate (5RE 0.2 )TaO 4 (Re=Y, Gd, Dy, Ce, Sm, La, Yb) ceramics were prepared by high temperature solid state reaction. The phase composition, microstructure, thermophysical and mechanical properties and CMAS corrosion resistance of the obtained high-entropy (5RE 0.2 )TaO 4 ceramics were systematically investigated. The as-prepared five high-entropy rare-earth tantalate (5RE 0.2 )TaO 4 ceramics had monoclinic structure and uniform composition. The five (5RE 0.2 )TaO 4 ceramics all had lower Young’s modulus (135.06∼158.63 GPa), Vickers hardness (3.7∼6.2 GPa), fracture toughness (2.30-2.80 MPa·m 1/2 ) and brittleness index (1.45-2.53 μm –1/2 ) than that of YSZ. The thermal expansion rate and thermal expansion coefficients of the five (5RE 0.2 )TaO 4 ceramics were close to each other but showed higher value than that of single RETaO 4 (RE= Gd, Dy, Sm or Y) and lower value than that of YSZ. The thermal diffusivities and thermal conductivity of the five (5RE 0.2 )TaO 4 ceramics were lower than that of YSZ, YTaO 4 and GdTaO 4 at all temperature. During molten CMAS corrosion, CMAS melt diffused into the (5RE 0.2 )TaO 4 ceramics and then corroded (5RE 0.2 )TaO 4 grains, thereby forming a corrosion area composed of reaction layer and penetration layer. The CaO in penetrated CMAS melt could react with Ta element in (5RE 0.2 )TaO 4 ceramics to generate Ca 2 Ta 2 O 7 in the reaction layer and reduce the content of CaO in the penetrated CMAS melt, which increased the viscosity of the CMAS melt and inhibited the further penetration of CMAS into the ceramics. Based on the obtained results, the CMAS corrosion of (5RE 0.2 )TaO 4 ceramics was primarily controlled by the Ca 2 Ta 2 O 7 formation and the CMAS penetration.
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高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2024
·
IF 8.1
Shuguang Li,Jize Liu,Haibo Wu,Xinxin Zhang,Yanqiong Guo,Boyang Kang,Limin Zhao
Photocatalytic hydrogen production with simultaneous degradation of organic pollutants by using solar energy provide a promising strategy to solve the energy and environmental issue in the future. However, for onefold wide band-gap semiconductor, the poor photocatalytic efficiency limits its application on a large scale due to its easy recombination of photo-generated electron-hole pairs and low solar energy utilization. Herein, a novel Z-scheme BiVO 4 (040)-Bi-(NaYF 4 :Er,Yb,Tm@BiOBr)/Bi photocatalyst is prepared via photo-assisted isoelectric point method. In this composite photocatalyst, up-convention luminescence material, NaYF 4 :Er,Yb,Tm, can offer more ultraviolet light and visible light to intensify the activations of BiOBr and metal Bi nanoparticles, respectively. Furthermore, the formation of Z-scheme BiVO 4 (040)-BiOBr photocatalystic sytem, the spatial separation of the BiVO 4 (040) and BiVO 4 (110) facets and the presence of metal Bi surface plasmon resonance effect are contributed to the high-efficiency separation of the photo-generated electron-hole pairs. The experimental results show that as-prepared Z-scheme BiVO 4 (040)-Bi-(NaYF 4 :Er,Yb,Tm@BiOBr)/Bi photocatalyst exhibits advanced photocatalytic hydrogen production amount (192.0 μm) and excellent degradation ratio of malachite green (88.51 %) under simulated sunlight irradiation for 5.0 h. The apparent quantum yield of the Z-scheme BiVO 4 (040)-Bi-(NaYF 4 :Er,Yb,Tm@BiOBr)/Bi photocatalyst at 420 nm reaches a specific value of 5.8 %. In addition, Z-scheme BiVO 4 (040)-Bi-(NaYF 4 :Er,Yb,Tm@BiOBr)/Bi photocatalyst also remains a high stability in the photocatalytic hydrogen production with simultaneous degradation of malachite green within six reuse. At last, the possible reaction mechanism and degradation pathways of malachite green caused by Z-scheme BiVO 4 (040)-Bi-(NaYF 4 :Er,Yb,Tm@BiOBr)/Bi photocatalyst under simulated sunlight irradiation are put forward.
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高影响因子
MICROCHIMICA ACTA
·
2018
·Vol. 185
·期 3
·1-9
·
IF 5.705
Li Yuemei,Li Yongmei,Wang Rui,Zheng Wei
Optical sensing of temperature by measurement of the ratio of the intensities of the 700 nm emission and the 800 nm emission of Ga(III)-doped ZnO (GZO) nanoparticles (NPs) and of GZO NPs coated with a silica shell are demonstrated at 980 nm excitation. It is found that the relative sensitivity of SiO 2 @Yb/Tm/GZO is 6.2% K −1 at a temperature of 693 K. This is ~3.4 times higher than that of Yb/Tm/GZO NPs. Obviously, the SiO 2 shell structure decreases the rate of the nonradiative decay. The decay time of the 800 nm emission of the Yb/Tm/GZO NPs (15 mol% Ga; 7 mol% Yb; 0.5 mol% Tm) displays a biexponential decay with a dominant decay time of 148 μs and a second decay time of ~412 μs. The lifetime of the Yb/Tm/GZO NPs at 293 K, and of the SiO 2 @Yb/Tm/GZO NPs are ~412 μs. Both the Yb/Tm/GZO and SiO 2 @Yb/Tm/GZO can be used up to 693 K. These results indicate that the SiO 2 shell on the Yb/Tm/GZO is beneficial in terms of sensitivity and resolution.
The enhancement the decay time and thermal sensitivity in the SiO 2 @Yb/Tm/GZO shell@core structure have been studied compared to the Ga(III)-doped Yb/Tm-doped ZnO (Yb/Tm/GZO). The SiO 2 @Yb/Tm/GZO have good thermal accuracy up to 693 °C.
研究领域:
光学传感
·
纳米材料
·
热力学测量
·
稀土掺杂材料
·
无机功能材料
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高影响因子
危险品化学品经营许可证（带存储）