JOURNAL OF NANOBIOTECHNOLOGY
·
2023
·Vol. 21
·期 1
·1-20
·
IF 10.2
Li Jiaxin,Li Weichang,Kong Mengjie,Li Zongtai,Yang Tao,Wang Qinmei,Teng Wei
Guided bone regeneration (GBR) is widely used in treating oral bone defects to exclude the influence of non-osteogenic tissue on the bone healing process. The traditional method of GBR with a titanium mesh to treat large-area bone defects is limited by the deficiency of increased trauma and costs to patients. Herein, a bi-layered scaffold for GBR composed of a fiber barrier layer and a self-healing hydrogel repair layer is successfully fabricated. The barrier layer is a fibrous membrane material with specific porosity constructed by electrospinning, while the functional layer is a self-healing hydrogel material formed by multiple dynamic covalent bonds. The system can provide an osteogenic microenvironment by preventing the infiltration of connective tissue to bone defects, maintain the stability of the osteogenic space through the self-healing property, and regulate the release of bioactive substances in the dynamic physical condition, which is beneficial to osteoblast proliferation, differentiation, and bone regeneration. This study focused on exploring the effects of different crosslinkers and bonding methods on the comprehensive properties of hydrogels. and proved that the hybrid scaffold system has good biocompatibility, cell barrier function and can enhance bone regeneration activity. Thereby it could be a promising clinical strategy for bone regeneration.
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高影响因子
FIBERS AND POLYMERS
·
2023
·Vol. 24
·期 3
·885-892
·
IF 2.5
Du Qiuping,Yu Jiajing,Xu Xianlin,Xia Lei,Zhuang Xupin
Developing a reusable, low cost and biodegradable oil absorption material with high capacity remains a challenge. Herein, we demonstrate a facile and reliable methodology to construct a hydrophobic cellulose sponge from cellulose xanthate by regenerating cellulose and surface silanization using methyl trichlorosilane. The cellulose sponge presents high porosity of up to 87.46% which could be regulated with p-Toluenesulfonyl hydrazide. The sponge exhibits excellent structure stability, which could complete recovery from 90% compression strain and high durability (60 cycles at 90% stain). With a hydrophobic surface, it presents a high absorption capacity of over 30 times its weight for oils and organic solvents, indicating promising application in oil and water separation.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
·
2023
·Vol. 34
·期 2
·1-12
·
IF 3.7
Wang Yixi,Ding Chuanyang,Ge Zhangjie,Li Zhipeng,Chen Lixin,Guo Xiaolong,Dong Genxi,Zhou Ping
Many kinds of antibacterial coatings have been designed to prevent the adherence of bacteria onto the surface of a fixed orthodontic device of brackets. However, the problems such as weak binding force, undetectable, drug resistance, cytotoxicity and short duration needed to be solved. Thus, it has great value in developing novel coating methods with long-term antibacterial and fluorescence properties according to the clinical application of brackets. In this study, we synthesized blue fluorescent carbon dots (HCDs) using the traditional Chinese medicinal honokiol, which could cause irreversible killing effects on both gram-positive and gram-negative bacteria through positive charges on the surface and inducing reactive oxygen species (ROS) production. Based on this, the surface of brackets was serially modified with polydopamine and HCDs, taking advantage of the strong adhesive properties as well as the negative surface charge of polydopamine particles. It is found that this coating exhibits stable antibacterial properties in 14 days with good biocompatibility, which can provide a new solution and strategy to solve the series of hazards caused by bacterial adhesion on the surface of orthodontic brackets. Graphical Abstract
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Advanced Fiber Materials
·
2023
·Vol. 5
·期 3
·1008-1024
·
IF 16.1
Wang Qianyi,Ran Xinyue,Wang Jian,Wang Sinan,Zhang Peiling,Gao Erji,Bai Baoshuai,Zhang Junfeng,Zhou Guangdong,Lei Dong
Tissue engineering provides a promising approach for regenerative medicine. The ideal engineered tissue should have the desired structure and functional properties suitable for uniform cell distribution and stable shape fidelity in the full period of in vitro culture and in vivo implantation. However, due to insufficient cell infiltration and inadequate mechanical properties, engineered tissue made from porous scaffolds may have an inconsistent cellular composition and a poor shape retainability, which seriously hinders their further clinical application. In this study, silk fibroin was integrated with silk short fibers with a physical and chemical double-crosslinking network to fabricate fiber-reinforced silk fibroin super elastic absorbent sponges (Fr-SF-SEAs). The Fr-SF-SEAs exhibited the desirable synergistic properties of a honeycomb structure, hygroscopicity and elasticity, which allowed them to undergo an unconventional cyclic compression inoculation method to significantly promote cell diffusion and achieve a uniform cell distribution at a high-density. Furthermore, the regenerated cartilage of the Fr-SF-SEAs scaffold withstood a dynamic pressure environment after subcutaneous implantation and maintained its precise original structure, ultimately achieving human-scale ear-shaped cartilage regeneration. Importantly, the SF-SEAs preparation showed valuable universality in combining chemicals with other bioactive materials or drugs with reactive groups to construct microenvironment bionic scaffolds. The established novel cell inoculation method is highly versatile and can be readily applied to various cells. Based on the design concept of dual-network Fr-SF-SEAs scaffolds, homogenous and mature cartilage was successfully regenerated with precise and complicated shapes, which hopefully provides a platform strategy for tissue engineering for various cartilage defect repairs. Graphical Abstract
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2023
·Vol. 30
·期 17
·51061-51074
·
IF 5.8
Zheng Siheng,Sheng Feng,Gu Cheng,Li Yanying,Fang Zhou,Luo Jun
Triazines are frequently detected in nature water and agricultural soils worldwide. They are considered harmful to plants, animals, and the human health. In this study, diffusive gradients in thin films (DGT) method was developed for the assessment of several triazines. DGT device was used for the in situ measurement of atrazine in a pesticide factory and obtained reliable data. The atrazine concentrations measured by DGT, and solvent extraction method was in a constant ratio. The DIFS model was coupled with DGT technique to study the desorption kinetics of atrazine in four kinds of different soils. The yellow–brown soil was more inclined to adsorb atrazine than other three soils. 2_D DIFS model was used to obtain the partition coefficient for labile atrazine ( K dl ), the values of the response time ( T c ), and desorption/adsorption rates ( k 1 and k −1 ). The yellow–brown soil has a larger labile pool size, and a faster resupply speed of atrazine. The 1_D DIFS model was used to simulate the profiles of atrazine concentrations in soil solution and solid phase. The results show that the desorption of atrazine in soil was limited by kinetic limitation at short time, and was limited by the solid phase reservoir at long time.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2023
·Vol. 30
·期 17
·50815-50828
·
IF 5.8
Chen Chen,Sun Hao,Zhang Shengyu,Su Xiaosi
In this study, stalk biochar (BC) was prepared by a high-temperature pyrolysis process and used as a non-metallic catalyst to activate peroxydisulfate (PDS) to degrade tetracycline hydrochloride (TCH). Various characterization results showed that BC had a hollow tubular structure, irregular folds, and important active sites such as oxygen-containing functional groups. Under the optimal reaction conditions, the degradation rate of TCH reached 98.1% within 120 min. In addition, the degradation performance was satisfactory and similar under acidic and near neutral pH, and higher temperature promoted the degradation of TCH. The SO 4 · − , ·OH, and 1 O 2 generated by PDS activation were reactive oxygen species (ROS), which degraded TCH through free radical/non-radical synergistic pathways. Quenching experiments proved that the generated SO 4 · − and ·OH might be the dominant reactive oxygen species (ROS) during the oxidative reaction. The research results will provide a theoretical basis for the application of PDS activated by non-metallic catalysts in the remediation of tetracycline antibiotics pollution.
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高影响因子
Friction
·
2023
·Vol. 11
·期 5
·801-819
·
IF 6.8
Liu Chenxu,Tian Yu,Khan Zulfiqar A.,Meng Yonggang
Corrosion and corrosive wear occur commonly on metals surface in aqueous solutions. External electric field is usually considered as one of the factors to accelerate corrosion or corrosive wear of materials in the presence of conventional electrolytes. This work aims to reposition widely believed perspective by experimental justification which have been conducted in aqueous solutions containing surfactants. Electric potential of metal surfaces was modulated externally within the electrochemical potential window of the metal electrode-solution-counter electrode system, which actively regulated the adsorption or desorption of surfactant molecule in the aqueous solution over the electrodes to form a molecular barrier of electron transportation across the electrode-electrolyte interface. The advantage of the approach over the anodic passivation is negligible redox reactions on the protected electrode surface while a better lubricious and wear resistant film than oxide is maintained in the meantime. Tribopairs of several metal/metal and metal/ceramic were tested by employing a ball-on-disc tribometer with anionic and cationic surfactants solutions. For anionic surfactant as the modifier, positive surface potential enables coefficient of friction to be decreased by promoting the formation of adsorption film on metal surface in aqueous solutions. For cationic surfactant, negative surface potential plays a role in decreasing the coefficient of friction. Phase diagrams of friction and wear in wide ranges of surfactant concentration and surface potential were plotted for the tested metal/metal and metal/ceramic tribopairs. These results indicate that the adsorption behavior of molecules or ions at the metal-aqueous interface can be well regulated when an external electric field is present without inducing corrosion or corrosive wear.
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Science China-Materials
·
2022
·Vol. 66
·期 4
·1659-1669
·
IF 8.64
Yin Yue,Chen Hongbin,Lin Pengcheng,Yu Weitai,Cao Xiaobao,Sheng Xinxin,Puigmartí-Luis Josep
Fluorescent metal-organic frameworks (FMOFs) have emerged as promising materials for optoelectronic and biological applications. However, their widespread use in these areas is limited due to some major drawbacks. First, it is difficult to construct flexible free-standing platforms with FMOF crystals. Moreover, these materials exhibit a low optical stability against external stimuli, and frequently, the metal ions used for their synthesis are toxic. Herein, a coaxial microfluidic spinning approach is developed to continuously generate core-shell FMOF-based microfibers in a one-step and large-scale fashion. The free-standing FMOF-based microfibers obtained showcase a high tensile strength of 85.6 MPa, the highest tensile strength reported for polymer@MOF-based composites. Moreover, it is also demonstrated that the cross-linked hydrogel shell generated with our microfluidic approach can effectively improve the optical stability of the FMOF crystals located at the core of the microfibers against a solution containing chemical species that can damage the FMOF crystals (e.g., a metal ion), acid and/or alkali treatments as well as heat. Most importantly, the FMOF-based microfibers exhibit high cell viability (ca. 96.6%) and versatile extracellular fluorescence imaging capabilities owing to both the biocompatibility of the hydrogel shell and the intrinsic fluorescence of the micofibers core. Accordingly, the herein reported flexible FMOF-based microfibers provide an advanced platform to design new concepts and material assemblies for optical and biomedical applications.
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2022
·Vol. 39
·期 6
·928-932
·
IF 2.726
Xu Zhonghang,Wu Yuanyu,Tao Ran,Jin Zhanbin,Fang Xuedong
I n recent years, many effective photocatalysts have been developed to solve the problem of environmental pollution and clean energy shortage. In this paper, non-noble metal cocatalyst Ni 3 N nanoparticles supported Zn 0.5 Cd 0.5 S(ZCS) nanorods(Ni 3 N/ZCS) composites were successfully synthesized by ultrasonic method. The hydrogen production efficiencies of the photocatalysts were tested under visible light, which was found that when the loading of Ni 3 N was 2% of the mass of ZCS, and the Ni 3 N/ZCS composite had the best hydrogen evolution performance, which could reach 70.3 mmol·h −1 ·g −1 . In addition, the quantum efficiency under 420 nm monochromatic light irradiation was 27.2%. Through different characterization analyses, such as X-ray diffraction(XRD), scanning electron microscopy(SEM), and UV-Vis diffuse reflectance spectra(DRS), a possible photocatalytic mechanism was proposed, providing some reference value for non-precious metals as cocatalysts.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2022
·Vol. 20
·期 1
·1-14
·
IF 9.429
Ruan Shuangrong,Yin Weimin,Chang Jiao,Yang Yan,Sun Jiuyuan,Ma Xiaoyi,Liu Ying,Zang Jie,Liu Yiqiong,Li Yongyong,Ren Tianbin,Dong Haiqing
Hypoxia and high accumulation of lactic acid in the tumor microenvironment provide fertile soil for tumor development, maintenance and metastasis. Herein, we developed a calcium peroxide (CaO2)-loaded nanostructure that can play a role of “one stone kill two birds”, i.e., acidic and hypoxic tumor microenvironment can be simultaneously regulated by CaO2 loaded nanostructure. Specifically, CaO2-loaded mesoporous polydopamine nanoparticles modified with sodium hyaluronate (denoted as CaO2@mPDA-SH) can gradually accumulate in a tumor site. CaO2 exposed in acidic microenvironment can succeed in consuming the lactic acid with oxygen generation simultaneously, which could remodel the acid and hypoxia tumor microenvironment. More importantly, the relief of hypoxia could further reduce lactate production from the source by down-regulating the hypoxia inducible factor-1α (HIF-1α), which further down-regulated the glycolysis associated enzymes including glycolysis-related glucose transporter 1 (GLUT1) and lactate dehydrogenase A (LDHA). As a result, CaO2@mPDA-SH alone without the employment of other therapeutics can dually regulate the tumor hypoxia and lactic acid metabolism, which efficiently represses tumor progression in promoting immune activation, antitumor metastasis, and anti-angiogenesis.
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JOURNAL OF MATERIALS SCIENCE
·
2019
·Vol. 54
·期 18
·11827-11840
·
IF 3.442
Zuo Yuxin,Yao Zhengjun,Lin Haiyan,Zhou Jintang,Guo Xinlu,Cai Haishuo
Carbonyl iron powder (CIP) coated with a layer of epoxy (EP) shell, denoted as core–shell CIP@EP composites, were designed and prepared via in situ polymerization. The CIP@EP composites containing 4.5–6.8 wt% EP were systematically characterized by X-ray diffraction, Fourier transform infrared spectroscopy, vibrating sample magnetometer, scanning and transmission electron microscopy, and vector network analyzer. The results indicated that CIP@EP composites with 9–254 nm EP shell thickness were successfully prepared through an efficient in situ polymerization method. The particle diameter of core CIP particles was 0.49–4.24 µm. The microwave absorption properties of the microspheres were then experimentally measured, and the CIP@EP composites exhibited a maximum reflection loss value of − 66.2 dB at 7.1 GHz at 2.0 mm absorber thickness. The effective absorbing bandwidth below − 10 dB was 8.0 GHz (from 10.0 to 18.0 GHz). The presence of the EP shell not only enhanced the microwave absorption performance of CIP@EP composites but also improved the overall chemical stability of CIP particles. The as-prepared CIP@EP composites may be a promising candidate for electromagnetic wave absorption applications, and the core–shell structure design can be extended to other microwave absorption materials.
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Microfluidics and Nanofluidics
·
2019
·Vol. 23
·期 4
·1-8
·
IF 2.437
Qin Weiwei,He Yang,Xiao Jinyi,Liang Shengwang,Wang Shumei,Li Paul C. H.,Sun Yue
Liquid–liquid solvent extraction is frequently used in the purification of active ingredients from plants, and repeated extraction by different solvents with different polarity is often demanded to improve purity. According to this demand, two kinds of laminar flow extraction were designed on the microfluidic chip, i.e. a three-phase laminar chip and a successive laminar flow chip, and compared with a current two-phase chip. P. ginseng was used as a model plant to demonstrate extraction performance, and ether and n -butanol were used as the degrease solvent and extraction solvent, respectively. The results demonstrated that the extraction efficiency of a successive laminar flow chip is higher than that of a three-phase laminar flow chip, and that of both chips are higher than that of a two-phase chip. The chip method provided a new way to extract active ingredients from plants, which should be easily automated and integrated with other units to develop a complex system for sample preparation and ingredient detection.
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