BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
·
2017
·Vol. 99
·期 4
·438-444
·
IF 1.412
Wang Se,Wang Zhuang,Chen Mindong,Fang Hao,Wang Degao
Combined toxicity and oxidative stress biomarker responses were determined for tetrabromobisphenol A (TBBPA) and sulfadiazine (SDZ) to the unicellular green alga Scenedesmus obliquus . Concentration–response analyses were performed for single toxicants and for mixtures containing TBBPA and SDZ with two different mixture ratios. The effect concentrations and the observed effects of the mixtures were compared to the predictions of the joint toxicity by the concentration addition (CA) model and independent action (IA) model. Results showed that the observed joint toxicity was within the scope of the highest (TBBPA) and lowest (SDZ) toxicity observed for the individual components. Furthermore, co-exposure of S. obliquus to TBBPA and SDZ provided preliminary evidence that the mixtures induced oxidative stress leading to cell damage. The CA and IA models proved to be valid for the prediction of the joint toxicity of TBBPA and SDZ. This study highlights a combined environmental risk assessment for two emerging pollutants.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2026
·Vol. 37
·期 26
·2039
·
IF 3.2
Wang Yue,Wang Xin,Chen Zhiwu,Lu Zhenya
BiFeO 3 –BaTiO 3 (BF–BT)-based piezoelectric ceramics have attracted significant attention due to their high Curie temperature ( T C ) and high residual polarization ( P r ), making them a highly promising lead-free piezoelectric ceramic system. However, their poor piezoelectric performance severely limits their practical applications. In this study, using the solid-state reaction method, we systematically investigated the addition of Sr(Zr 0.5 Ti 0.5 )O 3 (SZT) on the crystal structure, microstructure, dielectric, ferroelectric, and piezoelectric properties of (0.7− x )BiFeO 3 –0.3BaTiO 3− x Sr(Zr 0.5 Ti 0.5 )O 3 ( x = 0–0.008) ceramics. The results indicate that the introduction of SZT effectively suppresses the formation of Bi 25 FeO 40 , improves sintering density, and promotes grain growth (the average grain size reaches 4.82 μm at x = 0.006). More importantly, SZT doping caused Sr 2+ to further enhance the eccentric displacement of A-site ions; this localized structural distortion, in synergy with the transition of Bi 3+ from a disordered to an ordered arrangement under an external electric field, significantly improved the piezoelectric properties of the ceramics. At the same time, doping effectively suppressed changes in the valence state of Fe 3+ , thereby reducing leakage current. When x = 0.006, the material exhibited optimal overall electrical properties: The piezoelectric constant d 33 reached ~ 197 pC/N, and the electromechanical coupling coefficient k p was 0.336, representing increases of 48 and 39%, respectively, compared to the undoped sample ( d 33 = 133 pC/N, k p = 0.241). The residual polarization intensity P r reached as high as 29.9 μC/cm 2 , the Curie temperature reached 501 °C, and the material exhibited excellent temperature stability and large piezoelectric strain (0.249% @ 40 kV/cm, inverse piezoelectric coefficient d * 33 = 622.5 pm/V). This study not only verifies the significant performance enhancement of SZT doping on BF–BT-based piezoelectric ceramics but also provides an effective strategy and experimental basis for the development of lead-free piezoelectric materials that combine high-voltage electroactivity with high thermal stability.
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JOURNAL OF MATERIALS SCIENCE
·
2017
·Vol. 53
·期 4
·2351-2361
·
IF 2.599
Song Mei-Ru,Li Dong-Yao,Nian Fu-Yu,Xue Jin-Ping,Chen Juan-Juan
To improve the aqueous solubility and cancer targeting of the photosensitizers in photodynamic therapy (PDT), we encapsulated the photosensitizer in a biocompatibility and pH-sensitive drug delivery system, zeolitic imidazolate frameworks-8 (ZIF-8) nanospheres. Powder X-ray diffraction and electron microscopy show that our nanospheres are uniform and single-crystalline particles. Owing to the cleavage of zinc–ligand coordination bonds, more ZnPc–COOH were released much faster in the mild acidic conditions (pH 5.0 and 6.0) in comparison with physiological environment (pH 7.4). By incorporating ZnPc–COOH in ZIF-8, our nanospheres exhibited high singlet oxygen quantum yield and intracellular ROS generation. Cell viability experiments toward HepG2 cells demonstrated the low toxicity of ZIF-8 and the good anticancer efficacy of the nanospheres with low IC 50 values (4.2–4.9 μg/mL) under light illumination (670 nm, 1.5 J/cm 2 ). Collectively, these results suggested that our nanospheres are the promising pH-responsive drug delivery systems for PDT.
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Nano Research
·
2018
·Vol. 11
·期 9
·4859-4873
·
IF 7.994
Li Shi-Hua,Yang Wen,Liu Yang,Song Xiao-Rong,Liu Rui,Chen Guangliang,Lu Chun-Hua,Yang Huang-Hao
The promising potential of photodynamic therapy (PDT) has fueled the development of minimally invasive therapeutic approaches for cancer therapy. However, overcoming limitations in PDT efficacy in the hypoxic tumor environment and light penetration depth remains a challenge. We report the engineering of tungsten carbide nanoparticles (W 2 C NPs) for 1,064 nm laser-activated dual-type PDT and combined theranostics. The synthesized W 2 C NPs allow the robust generation of dual-type reactive oxygen species, including hydroxyl radicals (type I) and singlet oxygen (type II), using only single 1,064 nm laser activation, enabling effective PDT even in the hypoxic tumor environment. The W 2 C NPs also possess high photothermal performance under 1,064 nm laser irradiation, thus enabling synergistically enhanced cancer therapeutic efficacy of PDT and photothermal therapy. Additionally, the photoacoustic and X-ray computed tomography bioimaging properties of W 2 C NPs facilitate the integration of tumor diagnosis and therapy. The developed W 2 C based theranostic nanoagents increase the generation of reactive oxygen species in hypoxic tumors, improve the light penetration depth, and facilitate combined photothermal therapy and photoacoustic/computed tomography dual-mode bioimaging. These attributes could spur the exploration of transition metal carbides for advanced biomedical applications.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2019
·Vol. 17
·期 1
·1-15
·
IF 5.345
Qiang Lei,Cai Zheng,Jiang Wenjun,Liu Jiyong,Tai Zongguang,Li Guorui,Gong Chunai,Gao Shen,Gao Yuan
Background Macrophages with tumor-tropic migratory properties can serve as a cellular carrier to enhance the efficacy of anti neoplastic agents. However, limited drug loading (DL) and insufficient drug release at the tumor site remain the main obstacles in developing macrophage-based delivery systems. In this study, we constructed a biomimetic delivery system (BDS) by loading doxorubicin (DOX)-loaded reduced graphene oxide (rGO) into a mouse macrophage-like cell line (RAW264.7), hoping that the newly constructed BDS could perfectly combine the tumor-tropic ability of macrophages and the photothermal property of rGO. Results At the same DOX concentration, the macrophages could absorb more DOX/PEG-BPEI-rGO than free DOX. The tumor-tropic capacity of RAW264.7 cells towards RM-1 mouse prostate cancer cells did not undergo significant change after drug loading in vitro and in vivo. PEG-BPEI-rGO encapsulated in the macrophages could effectively convert the absorbed near-infrared light into heat energy, causing rapid release of DOX. The BDS showed excellent anti-tumor efficacy in vivo. Conclusions The BDS that we developed in this study had the following characteristic features: active targeting of tumor cells, stimuli-release triggered by near-infrared laser (NIR), and effective combination of chemotherapy and photothermotherapy. Using the photothermal effect produced by PEG-BPEI-rGO and DOX released from the macrophages upon NIR irradiation, MAs-DOX/PEG-BPEI-rGO exhibited a significant inhibitory effect on tumor growth.
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MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 7
·1-10
·
IF 6.232
Li Shanshan,Zhang Yintang,Mu Shuai,Ma Minrui,Liu Xiaoyan,Zhang Haixia
A novel magnetic organic porous polymer (denoted as Fe 3 O 4 @PC-POP) was developed for magnetic solid-phase extraction (MSPE) of two gastric cancer biomarkers (P-cresol and 4-hydroxybenzoic acid) from urine samples prior to high-performance liquid chromatographic analysis. The adsorbent was characterized by scanning electron microscope, transmission electron microscope, FTIR, powder X-ray diffraction, and other techniques. The result of dynamic light scattering shows that the particle size of the adsorbent is mainly distributed around 400 nm. Based on the design concept of the Fe 3 O 4 @PC-POP, the proposed material can effectively capture the target analytes through electrostatic and hydrophobic interaction mechanism. Furthermore, the enrichment conditions were optimized by the response surface method, and the method was utilized for the determination of P-cresol and 4-hydroxybenzoic acid in real urine samples from health and gastric cancer patients with high enrichment factors (34.8 times for P-cresol and 38.7 times for 4-hydroxybenzoic acid), low limit of detection (0.9–5.0 μg L −1 ), wide linear ranges (3.0–1000 μg L −1 ), satisfactory relative standard deviation (2.5%–8.5%), and apparent recoveries (85.3–112% for healthy people’s and 86.0–112% for gastric cancer patients’ urine samples). This study provides a guided principle for design of the versatile polymer with specific capturing of the target compounds from complex biological samples.
Graphical abstract
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2016
·Vol. 51
·期 15
·7186-7198
·
IF 2.302
Zhang Luanluan,Du Jia,Ran Ting,Gao Hejun,Liao Yunwen
A novel composite material PIL@TiO 2 was synthesized by sol–gel method using zwitterionic ionic liquid (1-(3-sulfonic group) propyl-3-ethylimidazole). TiO 2 was uniformly loaded on PIL (poly(1-(3-sulfonic group) propyl-3-ethylimidazole)). The large specific surface area, unique microspore structure, negative effect, and synergistic effect were caused by PIL. PIL@TiO 2 can effectively improve the separation efficiency of the electron–hole photogeneration. The electron–hole pair and · OH play an important role in the photo-degradation. The structure of dye molecule is also an influencing factor for the degradation capacity. After five cycle experiments, PIL@TiO 2 still exhibited excellent photocatalytic efficiency to dye molecules and its photocatalytic efficiency is better than that of P-25 (nanoscale TiO 2 ) in the methyl orange and Rhodamine B solutions.
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JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2015
·Vol. 305
·期 2
·543-549
·
IF 1.034
Wang Youjia,Wu Lei,Yang Yunchang,Feng Wen,Yuan Lihua
A novel design based on condensation of a simple bifunctional monomer led to hydrogen-bonded oligoaramide extractant 1 that could segregate Th(IV) from rare earths(III) [REs(III)] and U(VI) under strongly acidic conditions in a highly efficient and selective fashion by solvent extraction process. The extractant demonstrated a high extractability of 94.5–99.0 % and selectivity for extraction of Th(IV) from REs in 2.0–6.0 M HNO 3 . Particularly, REs were extracted only in <9 % in a simulated multi-component mixture in 4.0 M HNO 3 , which contrasts sharply with 88 % extraction of Th(IV). The presence of NaNO 3 as the salting-out agent significantly improved the extraction selectivity of Th(IV).
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JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2015
·Vol. 308
·期 3
·1095-1102
·
IF 1.034
Wang Zhengshang,Wang Yun,Liao Jiali,Yang Yuanyou,Liu Ning,Tang Jun
Three types of graphene sheets (GS) were decorated by chemical oxidation, electrolysis and ball-milling, respectively. These oxidized samples were characterized using SEM, XRD, Raman, FT-IR and XPS, and then were employed to enrich U(VI) from aqueous solutions as a function of pH, contact time and initial concentration of U(VI). These results displayed that the quantities and types of oxygen-functional groups were extremely different through these methods, which highly determined the adsorption capacity of graphene oxide to uranium. This work may provide some helpful information to optimize these fabrication processes and improve the adsorption ability of GS to uranium.
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FIBERS AND POLYMERS
·
2022
·Vol. 23
·期 7
·1924-1933
·
IF 2.347
Wang Ping,Xia Yanzhi,Xu Changhai,Chen Shaojuan,Ning Xin,Miao Dagang
The difficulties associated with dyeing alginate fibers by conventional dyeing processes have been a major limitation hindering the large-scale application of alginate fibers in the textile industry. The main aim of this study is to use plasma equipment for free radical graft polymerization of methacryloyloxyethyl trimethylammonium chloride (DMC) to achieve a better dyeing effect on cationically modified alginate fibers by direct dyeing using a saltless dyeing process. The treated alginate fibers were dyed by direct dyes and characterized by SEM, FTIR-ATR, XPS, K / S value determination and single-fiber breaking strength analysis. The results show that the DMC was successfully grafted onto the alginate fibers, the modified alginate fibers had good dyeing ability with high K / S values; and the alginate fibers maintained their breaking strength of 2.33 cN/dtex after dyeing, corresponding to a decrease of only 15.5 % (red), 1.3 % (yellow), and 4.8 % (blue) compared to that of the original fiber. The dyed alginate fibers also showed good washing fastness, which was better than grade 4. All the results indicate that upon subjection to atmospheric plasma, DMC was efficiently embedded into the alginate fibers, making the fiber cationic and effectively overcoming the charge repulsion between the fiber and the dye under salt-free conditions. This study may provide a valuable method for the alginate fiber dyeing industry.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2021
·Vol. 32
·期 14
·19309-19326
·
IF 2.478
Li Xiali,Shi Liuwei,Chen Lei,Yang Wenyao,Zha Xiaoting,Wang Chengpeng,Xi Runhui,Xu Jianhua,Yang Yajie
Ceramic/polymer nanocomposites have shown great potential in high energy storage density capacitors for pulsed power applications. However, due to the difference in surface energy between inorganic fillers and polymers, the discharge energy density and efficiency of nanocomposites are limited. In this article, the BaTiO 3 (BT) nanowires (NWs) modified with dopamine (Dopa) was introduced into aromatic polythiourea (ArPTU) polymer matrix as composite for high-performance dielectrics. This is a new path about the introduction of a high dielectric constant ceramic into high dipole moment linear polymers (HDMLP), which produces the polymer composite with high energy storage density and high discharge efficiency. The composite ArPTU/BT NWs shows an energy density of 7.5 J cm −3 and high efficiency more than 90% is obtained under an electric field of 250 MV m −1 . It also has been found that the modification of BT NWs with the Dopa reduces the dielectric loss of composite effectively due to the good synergistic effective between ArPTU and BT NWs, and high stability of composite for energy storage is also achieved. This work provides an effective solution for achieving high energy storage density and high discharge efficiency in polymer dielectrics for practical capacitor applications.
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CELLULOSE
·
2016
·Vol. 24
·期 2
·1159-1170
·
IF 3.195
Jia Yaling,Hu Yiwei,Zheng Dandan,Zhang Guangxian,Zhang Fengxiu,Liang Yaojia
An efficient and durable formaldehyde-free flame retardant consisting of an ammonium salt of pentaerythritol tetraphosphoric acid (APTTP) was prepared by a solventless synthesis and characterized by Fourier-transform infrared (FT-IR) spectroscopy and nuclear magnetic resonance. The flame retardancy of the treated cotton fabric was enhanced, as assessed by limiting oxygen index (LOI), vertical flammability, and cone calorimetry measurements. The collected results demonstrated that cotton fabrics treated with APTTP exhibited high flame retardancy and excellent durability. Cotton fabric treated with a 140 g/L APTTP solution showed a LOI of 43.8%, and this value reduced to 26.9% after 50 laundering cycles. No after-flame and after-glow phenomena were presented during vertical flammability tests for all cotton fabrics treated with different concentrations of APTTP. Cone calorimetry results revealed a significant reduction in the intensity of the heat release rate and total heat release peaks. X-ray diffraction revealed that the crystalline particles of cotton fibers treated with APTTP were slightly affected compared with those of control sample. FT-IR spectroscopy results revealed that APTTP was grafted on the cotton fibers. Scanning electron microscopy showed that the surface of the treated cotton fibers remained smooth, while thermogravimetric analysis confirmed that the treated cotton fibers easily decomposed to form char. It was proposed that the flame retardant mechanism of APTTP occurred in the condensation phase.
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