Soft Matter
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2019
·Vol. 15
·期 11
·2319-2327
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IF 3.399
Na Qi,Hui Zhao,Qiaozhi Wang,Yan Qin,Hao Yuan,Ying Li
Quantum dots (QDs) are of great interest due to their excellent fluorescence properties and thus, they have been widely studied. Compared with the typical organometallic synthetic routes and hydrothermal methods usually carried out under high temperatures, methods employing colloidal templates can be used for preparing QDs in mild conditions and have gained increasing attention. In this prospect, a hydrogel is an ideal colloidal template for the preparation of QDs in an aqueous medium, while the related study for in situ preparation of QDs in a gel and the consequent functionalization of QDs are in demand. In this paper, we proposed a two-step method to prepare CdS QDs in a sodium alginate (SA) gel, which showed effective constraint in the uniform size distribution of QDs. Without the introduction of additional ligands, the prepared CdS–SA QDs exhibited responsiveness to pH and detection of Fe3+, thus providing a simplified way for the functionalization of QDs. CdS–SA QDs showed good biocompatibility and stability in a certain concentration, which indicated the prospective applications of CdS–SA QDs in the fields of biological labeling and environmental sensing.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2019
·
IF 6.361
Shengkai Yang,Kelei Zhuo,Dong Sun,Xiaohui Wang,Jianji Wang
Liquid phase exfoliation (LPE) method has great potential for the large-scale production of graphene due to its simplicity, scalability, and low cost. In this work, fulvic acid (FA) was chosen to assist the exfoliation of graphite into graphene for the first time via sonication in aqueous medium. The concentration of obtained graphene dispersion can reach 0.63 ± 0.04 mg mL −1 . The graphene flakes mostly consisted of 1–5 layers with sizes range in submicron to micron and few defects in the basal-plane. The π–π interaction between graphene and FA, along with the electrostatic repulsion between negatively charged FA, played a major role in stabilization of the graphene dispersion. By adjusting the pH of graphene dispersion to 14, the nanosheets of graphene came to flocculation . The formed graphene slurry is favorable for storage and transportation due to the greatly decreased volume. The annealed coating of FA-graphene on aluminum sheets was used as corrosion inhibitor for aluminum in 0.5 M H 2 SO 4 and 0.6 M NaCl solutions, with inhibition efficiencies of up to 85.5% and 99.4%, respectively. This shows that as-prepared graphene has great potential applications in the anti-corrosion of aluminum.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2019
·Vol. 26
·期 11
·11170-11178
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IF 2.914
Sun Kaixuan,Sun Yuanyuan,Gao Bin,Xu Hongxia,Wu Jichun
Retention and transport of sulfonamides (SAs) in subsurface can strongly affect groundwater quality. In this work, a range of laboratory batch sorption and column transport experiments were conducted to determine the effect of cation type in mixed Ca-Na systems on the retention and transport of two typical SAs, sulfadimethoxine (SDM) and sulfacetamide (SCA), in saturated limestone porous media. Column experimental data showed divalent cation Ca 2+ played a more important role than monovalent cation Na + in decreasing the transport of only SDM in co-cation systems in the saturated limestone media. Further, in the single-cation (i.e., including either Ca 2+ or Na + ) system, increasing ionic strength (IS) of either NaCl or CaCl 2 had little effect on SCA transport; however, increasing of IS of CaCl 2 promoted the retention of SDM in the saturated limestone porous media. This is mainly due to the cation bridging effect of Ca 2+ on SDM and limestone. Overall, SDM showed much higher retention in the limestone columns than SCA, which can be attributed to the two SAs’ different physicochemical properties. Moreover, limestone showed stronger ability to retain the two SAs than quartz sand. Findings in this study suggest that cation type and the concentration of certain electrolyte (e.g., CaCl 2 ) as well as medium type play an important role in controlling the environmental fate and transport of antibiotics.
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Journal of Functional Foods
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2019
·
IF 3.197
Junlei Liu,Huarong Huang,Zebin Huang,Yuran Ma,Lanyue Zhang,Yan He,Dongli Li,Wenfeng Liu,Susan Goodin,Kun Zhang,Xi Zheng
Eriocitrin is a flavonoid that is isolated from orange peel. Resveratrol is a polyphenol compound, which is present in various fruits, such as grapes. The aim of the present study was to investigate both in vitro and in vivo anti-inflammatory effects of eriocitrin combined with resveratrol using lipopolysaccharide (LPS)-induced RAW264.7 cells and a mouse model of ear edema. The results showed that eriocitrin combined with resveratrol strongly inhibited LPS-induced secretion of nitric oxide (NO), tumor necrosis factor-α (TNF-α), and Interleukin-1β (IL-1β). Moreover, Eriocitrin combined with resveratrol potently inhibited nuclear factor-κB (NF-κB), phosphor-STAT3, and phosphor-AKT, which was accompanied by inhibition of phosphorylation in mitogen-activated protein kinase (MAPK) signaling pathways . Treatment with eriocitrin combined with resveratrol alleviated edema and subcutaneous tissue inflammation caused by 12-O-tetradecanoylphorbol-13-acetate (TPA) in vivo . This study also demonstrated that treatment with eriocitrin and resveratrol decreased the levels of the pro-inflammatory cytokines TNF-α and IL-1β. The results of the present study indicate that eriocitrin combined with resveratrol effectively inhibits inflammatory responses both in vitro and in vivo .
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ACS Biomaterials Science & Engineering
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2019
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IF 4.511
Quan Wang,Dongqin Lei,Fan Chen,Yuanwei Chen,Xianglin Luo
Although smart polymer micelles able to respond to the tumor acid microenvironment are potential anticancer drug carriers, fruitful clinical application of these carriers is inadequate. For the purpose of finding the origin of the unsatisfactory therapeutic efficacy of pH-sensitive drug carriers with tertiary amine groups, we newly designed and synthesized poly{α-[4-(diethylamino)methyl-1,2,3-triazol]-caprolactone-co-caprolactone}-b-poly(2-methacryloyloxyethyl phosphorylcholine) (PDCL-PMPC), a biomimetic phosphorylcholine polymer with pH-ensitive groups. PDCL-PMPC self-assembles into small and uniform micelles as its counterpart poly(caprolactone)-b-poly(2-methacryloyloxyethyl phosphorylcholine) (PCL-PMPC) without pH-sensitive groups. The in vitro and in vivo properties of PDCL-PMPC and PCL-PMPC micelles are investigated in detail. PDCL-PMPC micelles display obvious pH sensitivity by micelle change and fast drug release at pH 5, but the insensitive micelles do not. The internalization of PDCL-PMPC micelles by tumor cells is stronger than that of PCL-PMPC micelles. However, in comparison with the insensitive micelles, the pH-sensitive micelles present much shorter blood circulation time in pharmacokinetics and demonstrate worse accumulation in the tumor site in vivo study. As a result, DOX loaded PCL-PMPC micelles demonstrate much better antitumor efficiency than pH-sensitive micelles. Furthermore, DOX loaded PCL-PMPC micelles show similar therapeutic efficacy to DOX·HCl but with considerably lower side effects.
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ENVIRONMENTAL SCIENCE & TECHNOLOGY
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2019
·
IF 7.149
Qiuying Yi,Jiahui Ji,Bin Shen,Chencheng Dong,Jun Liu,Jinlong Zhang,Mingyang Xing
As an important reactive oxygen species (ROS) with selective oxidation, singlet oxygen (1O2) has wide application prospects in biology and the environment. However, the mechanism of 1O2 formation, especially the conversion of superoxide radicals (·O2–) to 1O2, has been a great controversy. This process is often disturbed by hydroxyl radicals (·OH). Here, we develop a molybdenum cocatalytic Fenton system, which can realize the transformation from ·O2– to 1O2 on the premise of minimizing ·OH. The Mo0 exposed on the surface of molybdenum powder can significantly improve the Fe3+/Fe2+ cycling efficiency and weaken the production of ·OH, leading to the generation of ·O2–. Meanwhile, the exposed Mo6+ can realize the transformation of ·O2– to 1O2. The molybdenum cocatalytic effect makes the conventional Fenton reaction have high oxidation activity for the remediation of organic pollutants and prompts the inactivation of Staphylococcus aureus, as well as the adsorption and reduction of heavy metal ions (Cu2+, Ni2+, and Cr6+). Compared with iron powder, molybdenum powder is more likely to promote the conversion from Fe3+ to Fe2+ during the Fenton reaction, resulting in a higher Fe2+/Fe3+ ratio and better activity regarding the remediation of organics. Our findings clarify the transformation mechanism from ·O2– to 1O2 during the Fenton-like reaction and provide a promising REDOX Fenton-like system for water treatment.
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CARBOHYDRATE POLYMERS
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2019
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IF 6.044
Xiahui Wang,Shouqing Cui,Jiajun Hu,Xiubing Ma,Tian-Ao Zhang,Yiu Fai Tsang,Jixiang Li,Min-Tian Gao
The bioconversion of rice straw into ethanol can alleviate the energy crisis and solve problems related to waste treatment. In this study, the effect of soluble polysaccharides (SPs) produced during rice straw saccharification on the formation of extracellular matrices (EMs) by the yeast Saccharomyces cerevisiae was investigated. SPs were characterized by high-performance liquid chromatography (HPLC) and fourier transform infrared spectroscopy (FT-IR). SPs reduced the inhibition of alcohol dehydrogenase activity by phenolic acids (PAs) and regulated the intracellular redox state, resulting in higher ethanol production. The results of flow cytometry, confocal laser scanning microscopy, and atomic force microscopy indicated that PAs changed microbial morphology and caused damage in microbial cell membranes. The protective effect of SPs against cell membrane damage could be attributed to the synthesis of polysaccharide-dependent extracellular matrix, which maintained cellular integrity even under phenolic acid stress. These findings provide new strategies to improve pretreatment and saccharification processes.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2019
·Vol. 411
·期 12
·2545-2553
·
IF 3.286
Du Fangkai,Li Mengru,Wei Yanye,Huang Donglian,Zhou Yan,Yang Lifang,Chen Jian,Liu Shaogang,Tan Xuecai
The design of vigorous tools for creatinine determination is extremely important in the diagnosis and treatment of kidney diseases. In the study, we examine a robust fluorescent turn-on probe (NCP-Pd) for creatinine detection in a completely aqueous solution based on the metal palladium-catalyzed reaction. In the presence of creatinine, the NCP-Pd dissociates and subsequently restores the fluorescence due to elimination of the heavy atom quenching effect and prevention of the photoinduced electron transfer effect. The probe NCP-Pd displays excellent detecting performance with respect to creatinine such as good water solubility, high selectivity, and a low detection limit (0.16 μM). Additionally, in order to ensure its clinical application, this probe is operated in blood serum samples for detecting creatinine and compared with a commercial clinical method. The results indicate an extremely high agreement with the commercial clinical method. Furthermore, the results confirm that the probe NCP-Pd exhibits satisfactory cell permeability and low cytotoxicity and can detect creatinine in L929 and HCT116 cells. The study provides a potential application for detecting creatinine and conducting pathological research on creatinine-involved diseases.
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COMPOSITES PART B-ENGINEERING
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2019
·
IF 6.864
Rongxiu Ma,Yajing Wang,Houjuan Qi,Cai Shi,Guangbiao Wei,Lidong Xiao,Zhanhua Huang,Shouxin Liu,Haipeng Yu,Chunbo Teng,Hu Liu,Vignesh Murugadoss,Jiaoxia Zhang,Yonggui Wang,Zhanhu Guo
Wound dressings with high flexibility, mechanical strength , and porosity have received increasing attention. Herein, nanocomposite sponges of sodium alginate/graphene oxide (GO)/polyvinyl alcohol were prepared by a freeze-thawing cyclic process and freeze-dried molding. The properties of the sponges were investigated including morphology, mechanical properties , swelling, water vapor permeability, in vitro norfloxacin (NFX) release, antibacterial property , and biocompatibility as well as in vivo wound healing in a mouse model. A GO concentration of 1 wt% resulted in the sponges with a homogeneously porous and interconnected network structure, which exhibited suitable water absorption, breathability , and mechanical properties. Hemolysis tests indicated that the prepared sponges were non-hemolytic material. The CCK-8 assay demonstrated that the presence of an appropriate amount of GO could promote the cell proliferation . The sponges displayed excellent bioavailability of NFX, with a sustained release behavior and a strong inhibitory effect against both Escherichia coli and Staphylococcus aureus . The in vivo evaluations demonstrated that the sponges enhanced wound healing. Therefore, these novel nanocomposite sponges are promising candidates for wound healing applications.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2019
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IF 3.131
Xiuping Tang,Yu Hou,Qing Bo Meng,Guolin Zhang,Fuxin Liang,Xi-Ming Song
In this work, we developed a continuous non-aqueous flow Pickering emulsion interface catalysis (FPIC) system for heterogeneous acylation. Poly (1-vinyl-3-ethylimidazolium bromide) (PILs) functionalized silica@PS/PDVB Janus particles (JPs) were synthesized. The catalyst H 3 PW 12 O 40 (PA) was then immobilized on PIL-modified JPs by anion-exchanging. The PIL grafted on the silica side and the inherent oleophilic phenyl groups on the other side endow the Janus particle with excellent amphipathy for the immiscible ionic liquid (IL) [BMIM]BF 4 and toluene. Therefore, emulsification and catalytic capability were realized simultaneously on the PA-PILs-JPs. The FPIC column system for acylation reaction was accomplished by packing the IL-in-oil Pickering emulsion into a column reactor, and exhibited excellent catalytic performance, high stability during the reaction process as well as remarkable recyclability.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2019
·
IF 2.931
Deyang Fu,Weiru Zhi,Lihua Lv,Yi Luo,Xiaoqing Xiong,Xiaohui Kang,Wei Hou,Jun Yan,Hongjuan Zhao,Laijiu Zheng
Hydrogen sulfide (H 2 S), as the third multifunctional signaling biomolecule, it acts as a neuromodulator in the human brain and is recognized as an important gas transmitter in human physiology. The abnormal concentrations of H 2 S in human cells can result in several common diseases. Therefore, accurate, fast, and reliable methodologies are required for measuring the in vitro and in vivo concentrations of H 2 S to further investigate its function. In this study, a novel DR–SO 2 N 3 fluorescent probe containing the fluorophore Disperse Red 277 and a sulfonyl azide group was developed and exploited based on the structural characteristic of Disperse Red 277 that contains the active site easily can be attacked by HS − . Therefore, this probe featured two reaction sites that involved the reduction and Michael addition of H 2 S and exhibited rapid ratiometric fluorescence changes and high selectivity towards H 2 S with a 619-fold enhancement factor. Further, the density functional theory (DFT)/time-dependent density functional theory (TDDFT) studies are conducted to understand the photophysical properties of DR–SO 2 N 3 and the final product DRHS–SO 2 NH 2 , which makes the proposed mechanism more reasonable. Furthermore, the probe was successfully applied for the ratiometric fluorescence imaging of exogenous H 2 S in living cells.
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FOOD HYDROCOLLOIDS
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2019
·
IF 5.839
Shahid Iqbal,Zichong Xu,He Huang,Xiao Dong Chen
In this study the influence of oppositely charged protein and polysaccharide microspheres on the rheological properties of single and mixed water-in-oil emulsions was investigated. Single and mixed aqueous phases of 40 wt % W/O emulsions were prepared by dispersing, under controlled conditions (pH 3.5, 100 mM NaCl), Whey Protein Isolate (WPI) and three different kinds of polysaccharides: High Methoxy Pectin (HMP), kappa Carrageenan (kC), and sodium alginate (SA). The oil phase consisted of 8 wt % Polyglycerol polyricinoleate (PGPR) in soybean oil . At pH 3.5, WPI carries positively charged groups, while polysaccharides have negatively charged groups. It was observed that before heating, single W/O emulsions had higher complex shear modulus and shear viscosity than mixed emulsions, which suggested stronger protein-polysaccharide interactions in single droplet systems. After subjecting to a thermal treatment (90 °C, 30 min), the rheological properties of the mixed emulsions were higher than for equivalent single emulsions, suggesting denser gel network formation between opposite charged emulsion droplets, especially in the WPI-HMP mixed system. The data from this study may be useful for development of reduced-fat margarine and spreads with low saturated and trans fat content.
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