Sustainable Materials and Technologies
·
2025
·
IF 9.2
Hui Li,Ronghao Wu,Long Zhou,Zuliang Chen
In this study, a novel C-ZIF-8@Fe/REEs composite, fabricated from one-step pyrolysis using ZIF-8@Fe adsorbed with rare earth elements (REEs) as precursors was successfully used to activate peroxymonosulfate (PMS) for efficient oxidation of Bisphenol A (BPA). The as-prepared C-ZIF-8@Fe/REEs exhibited high PMS activation performance, with an BPA removal efficiency exceeding 95 % within 120 min. Characterizations revealed that the REEs introduction increased the exposure of active sites, and facilitates the electron transfer. Electron paramagnetic resonance analysis and quenching tests confirmed that both radical (·OH, ·SO 4 − ) and non-radical ( 1 O 2 , high-valent metals, and electron transfer) pathways were involved in BPA degradation. Reasonable BPA degradation pathways were proposed by analyzing the results of LC-MS and DFT calculations. Additionally, toxicity assessments demonstrated a significant reduction in the toxicity of degradation products. Finally, the synthesized composite exhibited excellent reusability and stability in real wastewater fixed column bed experiments, with the removal efficiency still be higher than 70 % after 11 h operation. These findings demonstrate that the recovery REEs from mining wastewater is an effective strategy in developing a highly efficient Fenton-like catalysts, and also highlight the promising role of using C-ZIF-8@Fe/REEs in wastewater treatment, particularly for the removal of organic contaminants.
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高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2024
·
IF 8.4
Wanzheng Ren,Jian Pan,Zhuoqun Li,Min Huang,Lilan Huang,Liqiang Gu,Hailin Cong
The substrate membrane plays a crucial role in determining the performance of composite nanofiltration membranes prepared by interfacial polymerization (IP). In this study, persistent hydrophilic modification of polyvinylidene fluoride-co-chlorotrifluoroethylene (PVDF-CTFE) was achieved by incorporating N-methylglucamine (N-MG) without altering the membrane's morphology or pore size. Moreover, thin-film nanofibrous composite (TFNC) nanofiltration membranes were prepared using the surfactant assembly regulated interfacial polymerization (SARIP) method with the modified PVDF-CTFE@N-MG nanofibrous membrane as the substrate. The effect of N-MG addition on the substrate membrane's hydrophilicity and the structure and performance of the polyamide (PA) separation layer was investigated. The results showed that the addition of N-MG significantly improved the hydrophilicity of the PVDF-CTFE nanofibrous membrane. The TFNC-5 membrane, prepared with the modified PVDF-CTFE@N-MG nanofibrous membrane as the substrate, exhibited permeability exceeding 13.5 L m −2 h −1 ·bar −1 for various dye solutions at 3 bar pressure, with rejection rates above 98 %. It also demonstrated excellent selective separation performance (separation factor for NaCl/Orange G reaching 97.38) and long-term operational stability. This work provides a method for the preparation of low-pressure, high-flux nanofiltration membranes, which is applicable to seawater desalination and dye wastewater treatment .
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高影响因子
Cell Reports
·
2025
·
IF 6.9
Qiang Zhang,Kaisa Cui,Yue Kong,Jing Yu,Zhanhao Luo,Xiaoya Yang,Liang Gong,Yanchun Xie,Jiuxiu Lin,Chen Liu,Zongjin Zhang,Yugeng Liu,Bingxin Liu,Dayi Liang,Wanyi Zeng,Zhen He,Ping Lan
c-Myc (Myc)-driven cancers exhibit aggressive phenotypes and therapeutic resistance. Here, integrating CRISPR-Cas9 screening, we identify dihydroorotate dehydrogenase (DHODH) as a promising target in Myc-driven cancer. Mechanistically, DHODH interacts with Myc to stabilize it independently of its enzymatic activity, thereby antagonizing SKP2-mediated polyubiquitination and proteasomal degradation. EN4, a Myc transcriptional activity inhibitor, disrupts DHODH-Myc interaction, promoting Myc degradation via SKP2. Additionally, Myc transcriptionally activates DHODH, enhancing pyrimidine biosynthesis and ferroptosis defense, processes dependent on DHODH enzymatic activity. Clinically, DHODH positively correlates with Myc, activating pyrimidine metabolism and ferroptosis defense in Myc-driven cancers. Hyperactivation of the DHODH-Myc axis is linked to colorectal cancer progression and poor prognosis. Therapeutically, combining EN4 with a DHODH enzymatic inhibitor demonstrates potent antitumor efficacy in Myc-driven colorectal cancer. Overall, our findings elucidate the metabolic and non-metabolic roles of DHODH in Myc-driven cancer, underscoring its dual potential as a therapeutic target addressing both enzymatic and non-enzymatic functions.
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PubMed
高影响因子
ADVANCED MATERIALS
·
2024
·Vol. 36
·期 25
·2400656
·
IF 27.4
Hanchen Wang,Yingtian Liu,Mingze Jiang,Yu-Xing Yao,Chunhua Hu,Chong Yan,Qiang Zhang,Luming Li
The advanced lithium-ion batteries that can tolerate zero-volt storage (ZVS) are in high demand for implantable medical devices and spacecraft. However, ZVS can raise the anode potential, leading to Cu current collector dissolution and solid-electrolyte interphase (SEI) degradation, especially at 37 °C. In this contribution, by quantitatively regulating the dosage of Li 6 CoO 4 cathode additives, controllable potential of the working anode under abusive-discharge conditions is demonstrated. The addition of Li 6 CoO 4 keeps zero-crossing potential (ZCP) and the potential of ZVS below 2.0 V (vs Li/Li + ) for LiCoO 2 |mesocarbon microbead cells at 37 °C. The capacity retention ratio (CRR) increases from 69.1% and 35.9% to 98.6% and 90.8% after 10 and 20 days of ZVS, respectively. The Cu dissolution and SEI degradation are effectively suppressed, while the over-lithiated cathode exhibits high reversible capacity after ZVS. The limiting conditions of long-term ZVS are further explored and a corresponding guide map is designed. When quantitatively regulating ZCP and the potential in ZVS, Cu dissolution, SEI degradation, and irreversible conversion of the cathode constitute the limiting conditions. This contribution designs the most reasonable potential range for ZVS protection at 37 °C, and realizes the best CRR record through precise potential regulation for the first time.
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高影响因子
Materials Today Communications
·
2024
·
IF 3.7
Zhenqiang Huang,Yanan Zhang,Ke Jia,Rui Zuo,Kemeng Ji,Mingming Chen
Lithium-sulfur batteries (LSBs) emerge as promising energy storage devices due to their high theoretical energy density . So far, there are constrained issues that need to be urgently addressed, such as the shuttle effect of lithium polysulfides (LiPS) and the sluggish kinetics of redox reactions . Herein, NiSe-Ni 2 P/C composite was synthesized and casted on the cathode side of polypropylene (PP) separator. This investigation reveals that the adsorption-catalysis synergistic effect of NiSe-Ni 2 P/C composite, accelerates the reduction of LiPS to lithium sulfide (Li 2 S) as well as the oxidation of Li 2 S. The synergistic effect effectively mitigates the shuttle effect of LiPS, reduces concentration polarization, and improves Coulombic efficiency (CE) throughout the entire lifespan. At a current density of 0.05 C, LSBs with NiSe-Ni 2 P/C modified PP separators exhibit a remarkable high initial CE of 97.0% and a substantial discharge specific capacity of 1205.4 mAh g s −1 . Even under conditions of a high sulfur loading (4.3 mg cm −2 ) and a limited electrolyte dosage (10 μL mg s −1 ), the LSBs maintained a reversible specific capacity of 804 mAh g s −1 , a CE of 94%, and an energy density of 1232.1 Wh kg s −1 after 720 h of continuous cycling at 0.05 C. This work provides a solution for achieving long-time, high-capacity, and high-CE electrochemical performance in LSBs with a high sulfur loading and a limited electrolyte dosage.
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高影响因子
International Journal of Electrochemical Science
·
2024
·
IF 1.3
Ya Zhang,Chen Tian,Ke Wang,Qiang Shen
The high temperature sintered ceramic pellets of solid electrolyte Li 1.3 Al 0.3 Ti 1.7 (PO 4 ) 3 (LATP), obtained in the absence of any sintering aids, should contain a large amount of interparticle gaps, which is one of the main bottlenecks in developing LATP-based all-solid-state Li-metal batteries. In this study, a facile solution (LiCl in ethanol) immersion method is adopted to soak the already 900℃-sintered LATP ceramic pellets, and the resulting series of LATP-xLiCl (x denotes the weight fraction of LiCl, 0.0 ≤ x ≤ 3.7) are assayed to address the high-performance mechanism of lithium-graphite (Li-C) symmetric cells. At the optimal x value of 2.3, the grain-boundary resistance of the ceramic pellet can be significantly reduced from 1772 to 28 Ω·cm² at room temperature, which endows the Li-C symmetrical cells of LATP-2.3LiCl with a high critical current density of 3.00 mA cm² at 60°C. Especially, the enhanced ionic conductivity of LATP-2.3LiCl (4.7×10 −4 S cm −1 , at 20℃; 1.1×10 −3 S cm −1 , at 60℃) indicates an effective strategy of utilizing capillary force to densify LATP-based ceramic pellets for potential application purposes.
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高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2022
·
IF 24.319
Na Ye,Pengcheng Zhao,Xiaoying Qi,Wenchao Sheng,Zhao Jiang,Tao Fang
The C C bond cleavage remains a main challenge for alkaline EOR (ethanol oxidation reaction). In this work, we report an efficient PdSn-TaN/C electrocatalyst to split the C C bonds in ethanol. Structurally, a series of characterization results confirm the presence of the low-coordinated Pd sites on the PdSn-TaN/C interface. The PdSn-TaN/C catalyst exhibits very high activity (almost 26.9 times of commercial Pd/C), good durability and high selectivity to CO 2 (20.5%) towards alkaline EOR. Specifically, in-situ ATR-SEIRAS (Attenuated total reflection-surface enhanced infrared absorption spectroscopy) results indicate that TaN facilitates the cleavage of C C bonds, whereas Sn promotes the further oxidation of ethanol fragments. DFT (density functional theory) calculations indicate the activation barriers of the C H bond cleavage in CH 3 CH 2 OH, CH 3 CHOH, CH 3 CHO, CH 3 CO, CH 2 CO and the C C bond cleavage in CH 3 CO, CH 2 CO, CHCO are reduced evidently and the removal of adsorbed CH 3 CO and CO becomes easier on the PdSn-TaN/C catalyst surface.
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高影响因子
IMMUNOLOGIC RESEARCH
·
2025
·Vol. 73
·期 1
·1-20
·
IF 3.1
Xu Cong,Lu Chenqi,Wang Wu,Wang Zhimin,Qiu Yang,Han Min,Yang Jun,Li Shanglin
Autoimmune hepatitis (AIH) is an immune-mediated liver disease that currently lacks viable drug treatment methods. This study is to explore the role of piceatannol (PIC) in ConA-induced AIH and the related mechanisms. A mouse model of AIH was established by injecting ConA (i.v.), and PIC was administered as an intervention. The protective effect of PIC was evaluated by the liver function, liver pathology, and serum levels of inflammatory factors. Subsequently, network pharmacology was used to predict the pathways and targets of PIC in the treatment of AIH, and the predicted results were validated using flow cytometry, molecular docking, surface plasmon resonance (SPR) and so on. Finally, the immunosuppressive effect of PIC was further validated in a mouse heart transplantation model. PIC can improve liver function decline and reduce pathological liver damage, as well as inhibit the increase of serum inflammatory factor levels in mice with AIH induced by ConA. The protective effect is achieved by suppressing the immune activity of T cells and macrophages through binding to c-Jun. PIC can also extend the survival of cardiac allografts and inhibit acute rejection reactions. These results indicated that PIC can significantly improve ConA-induced AIH in mice by inhibiting the immune activity of T cells and macrophages through binding to c-Jun. PIC can also extend the survival of cardiac allografts in mice and inhibit acute rejection responses. The above results indicated that PIC may serve as a promising immunosuppressant and be effective for AIH.
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高影响因子
ADVANCED MATERIALS
·
2025
·
IF 26.8
Min Wu,Shumin Liu,Haofu Yuan,Zichao Zhao,Lin Qiao,Xiangkun Ma
Iron-chromium flow batteries (ICFBs) are regarded as one of the most potential large-scale energy storage devices. Nevertheless, the slow dynamics of the Cr 3+ /Cr 2+ redox couples hinder the development of ICFBs. Here, a high-efficiency carbon-loaded bismuth (Bi/C) catalyst is fabricated and introduced on the electrode in situ to improve the dynamics with the assistance of polyvinylpyrrolidone (PVP). To derive the greatest value, we explore the current density anisotropy in ICFB and design a strategy of anisotropy engineering to meet the requirements of the anisotropy for catalysts. In the work, the gradient electrode (G-PBiC/TCF) with a high-efficiency Bi/C catalyst is successfully prepared. In addition, the ICFB assembled with the G-PBiC/TCF(M/m, the side of more catalysts facing the Membrane side) shows excellent battery performance. It can run over 500 cycles with EE of 81.36% at 120 mA cm −2 , which is the longest cycle life reported. Furthermore, the catalytic mechanism and the effect of the catalyst distribution on the performance are explained by the DFT calculation and multi-physical field simulation. This work provides a novel pathway to design that catalyst-supported gradient electrode with high performance and low cost.
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2022
·Vol. 32
·期 51
·2208676
·
IF 19.924
Bo Pang,Zuquan Jin,Yunsheng Zhang,Zhiyong Liu,Wei She,Penggang Wang,Yong Yu,Xiaoying Zhang,Chuansheng Xiong,Ning Li,Guowen Sun,Peng Zhao,Guojian Liu,Xiaoyun Song,Song Gao
Cement-based sensors (CBSs) have demonstrated potential in structural health monitoring (SHM) despite rare applications due to their poor flexibility and sensing accuracy/protection with robustness. Herein, a promising strategy is reported to design a waterborne epoxy resin (WEP)-modified cement-based composite coating sensorcapable of simultaneous stable SHM and durable protection. The interpenetrating network (IPN) formed by WEP within cement paste is bionic to the toughness and crack resistance of biological muscle tissue and balances the ion permeation performance and polarization of hydration products. The polymerization-redispersion progress and mechanism of calcium silicate hydrate (C-S-H) gel modified with [3-(2-aminoethylamino)-propyl]trimethoxysilane silsesquioxane (C-POSS) are characterized and revealed. The results show that the muscle-like IPN increases the cement-based coatings’ maximum deflection angle to 30° and improves the monitoring accuracy of compressive, tensile, and fatigue microchanges of concrete structures to more than 95%. The POSS···Ca 2+ ···C-S-H interaction in C-POSS partially transferred the intra-adhesive hydrogen bonds surrounding the nanoconducer into electrostatic bridging ones to maintain an excellent electromechanical conductive dispersion.
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2021
·Vol. 31
·期 36
·2103802
·
IF 18.808
Liang Cao,Bi Luo,Baohe Xu,Jiafeng Zhang,Chunhui Wang,Zhiming Xiao,Shanhong Li,Yangzhong Li,Bao Zhang,Guoqiang Zou,Hongshuai Hou,Xing Ou,Xiaobo Ji
Potassium-ion batteries (PIBs) have appealed increasing attention due to the inexpensive K-element resources and satisfactory electrochemical properties. Presently, there are still challenges for developing desirable anode materials. Two-dimensional metal sulfides exhibit high specific capacity as host for PIBs, yet the dissolution and agglomeration of unstable reaction intermediate K x S y (K 2 S, K 2 S 5 ) inescapability induces large loss of active ingredients and poor reactions reversibility, leading to inferior lifespan. Herein, polar polysulfide VS 4 is introduced into SnS nanosheets with constructing layered VS 4 /SnS heterostructure anchored in graphene scaffold (VS 4 /SnS@C). In this framework, VS 4 with unsaturated bridging (S 2 ) 2– can act as the anchoring sites to stabilize intermediates K x S y with efficient entrapment effects. Moreover, the heterostructure can maintain layered SnS and regulate the distribution of K x S y with high conversion reversibility. The reaction reversibility and intermediate absorptivity are enhanced, as confirmed by in situ X-ray diffraction analysis and theoretical calculations. Consequently, the VS 4 /SnS@C electrode exhibits ultra-long lifespans, which achieves a capacity of 168.4 mAh g –1 at 1 A g –1 after 6000 cycles. This strategy of heterostructure design facilitates the understanding of K-storage mechanisms and significantly enhances the reaction reversibility, providing a thought to address the challenges in metal sulfide anodes toward the development of high-performance PIBs.
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高影响因子
Advanced Science
·
2022
·Vol. 9
·期 26
·2201573
·
IF 17.521
Fangwen Cheng,Fang Cao,Binwen Chen,Xinfeng Dai,Ziheng Tang,Yifei Sun,Jun Yin,Jing Li,Nanfeng Zheng,Binghui Wu
Power conversion efficiency (PCE) and long-term stability are two vital issues for perovskite solar cells (PSCs). However, there is still a lack of suitable hole transport layers (HTLs) to endow PSCs with both high efficiency and stability. Here, NiO x nanoparticles are promoted as an efficient and 85 °C/85%-stable inorganic HTL for high-performance n-i-p PSCs, with the introduction of perovskite quantum dots (QDs) between perovskite and NiO x as systematic interfacial engineering. The QD intercalation enhances film morphology and assembly regulation of NiO x HTLs . Due to structure–function correlations, hole mobility within NiO x HTL is improved. And the hole extraction from perovskite to NiO x is also facilitated, resulting from reduced trap states and optimized energy level alignments. Hence, the promoted NiO x -based n-i-p PSCs exhibit high PCE (21.59%) and excellent stability (sustaining 85 °C aging in air without encapsulation). Furthermore, encapsulated solar modules with QDs-promoted NiO x HTLs show impressive stability during 85 °C/85% aging test for 1000 hours. With high transparency, QDs-promoted NiO x is also demonstrated to be an advanced HTL for semitransparent PSCs. This work develops promising NiO x inorganic HTL in n-i-p PSCs for manufacturing next-generation photovoltaic devices.
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高影响因子
危险品化学品经营许可证（带存储）