ATMOSPHERIC ENVIRONMENT
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2022
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IF 5.755
Wangjin Yang,Di You,Xiangli Nan,Ning Tang,Tao Du,Chong Han
The effects of aromatic carbonyls (ACs), polycyclic aromatic hydrocarbons (PAHs) and phenols (PHs) on the photolysis of nitroaromatic compounds (ArNO 2 ) in the solid phase were explored. The reactive nitrogen gas formation by the photolysis process was investigated in a cylindrical reactor coupled to a NO x analyzer. These organics had an enhanced or inhibited influence on the nitrous acid (HONO) and NO formations by the photolysis of 1-nitropyrene (NPy) and 5-nitrosalicylic acid (NSA), depending on the hydrogen abstraction and donation abilities of organics. Based on the high-performance liquid chromatography (HPLC) results, methyl-2-benzoylbenzoate (MBB), fluoranthene (FLA) and syringaldehyde (SG) showed a promoted effect on the photodegradation of NPy and NSA, as shown by an increase in the photolysis frequency of ArNO 2 ( J ArNO 2 ) by a factor of 1.19–2.76. Based on experimental results, the HONO source strength by the photolysis of ArNO 2 in organic aerosols was estimated to be lower than 1 ppt h −1 .
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2024
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IF 8
Jiali Qiao,Jingyu Jia,Weipan Peng,Minghui Lu,Yaru Li,Shuli Man,Shengying Ye,Long Ma
Early detection and control of foodborne diseases are crucial for ensuring food safety and consumer health. Therefore, there is a need for faster and more sensitive detection methods. We developed a rapid, portable and visible lateral flow biosensor (LFB) for foodborne pathogenic bacteria detection powered by a Pyrococcus furiosus Argonaute nuclease ( Pf Ago), named as Pf Ago-LFB. LAMP (Loop-mediated isothermal amplification) was used to amplify the target nucleic acid . By using Pf Ago as the “lighting up” technology, we can overcome the limitations of false-positive results and lack of effective endpoint monitoring in LAMP, greatly enhancing its applicability. It turned out that Pf Ago-LFB was able to provide yes-or-no (positive or negative) results with a limit of detection (LOD) as low as 1 CFU/mL for S. typhimurium and the detection range was between 10 0 to 10 8 CFU/mL. It was able to secure a sample-to-answer test for contaminated food samples in less than 45 min and demonstrated satisfactory selectivity. In summary, we designed a Pf Ago-LFB that rendered a novel, rapid, accurate, easy-to-deploy, on-site and yes or no detection of S. typhimurium , which could be generalized for building a “one-for-all” biosensing platform.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Yuerui Ma,Peng Chen,Jiazhen Liao,Xing’an Dong,Wenjie He,Wendong Zhang
Selective photocatalytic oxidation of NO to nitrate (NO 3 – ) over toxic NO 2 remains challenging due to low selectivity and inefficient charge migration in existing systems. This study introduces Fe 3+ as an electron acceptor beneath a Bi 4 TaO 8 Cl/Bi 2 O 2 CO 3 heterojunction to precisely regulate electron pathways and promote targeted hydroxyl radical ( • OH) generation. Combined experimental and DFT analyses reveal Fe 3+ ’s dual role: enhancing interfacial electron transfer and activating H 2 O at surface sites to form • OH. The optimized heterojunction achieves 68.19 % NO conversion with minimal NO 2 selectivity (10.98 %). ESR and ROS quenching confirm Fe 3+ -driven electron migration enriches surface holes, boosting H 2 O adsorption and • OH production (2.76-fold increase). The strong oxidation capacity of • OH suppresses NO 2 formation, favoring complete NO oxidation to NO 3 – . This work provides a strategic approach for selective NO removal by electron-pathway engineering, advancing the design of eco-friendly photocatalysts for air pollution control.
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POLYMER
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2025
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IF 4.5
Gang Tang,Yani Zhang,Feilong Wang,Zhenfeng Cheng,Haojie Shi,Tiwen Xu,Xiuyu Liu,Xin Wang
The flammability of bismaleimide (BMI) resins limits the application in cutting-edge fields. However, the addition of phosphorus-containing flame retardants results in deteriorated thermal stability of BMI resins. A phosphorus-free flame retardant strategy has been adopted to modify BMI resins while preserving high heat resistance. 3, 3’-Bisallyl-4,4’-bishydroxydeoxybenzoin (BA-BHDB) was synthesized from desoxyanisoin and used as a modifier for BMI resins by replacing conventional 2, 2’-diallylbisphenol A (DBA). The thermal, mechanical and flammability properties of BA-BHDB-cured BMI resins were investigated and compared with those of DBA-cured BMI resins. The cured BA-BHDB-BMI resins exhibit an LOI value for combustion of 35.0% and a UL-94 V-0 rating, whereas the cured DBA-BMI resins display a lower LOI value of 30.0% and a UL-94 V-1 rating. In the cone calorimeter measurements, the PHRR and THR values for combustion of BA-BHDB-BMI were 381.1 kW/m 2 and 92.5 MJ/m 2 , which were 53.2% and 25.2% lower than those of DBA-BMI, respectively. Additionally, the heat resistance of the cured BA-BHDB-BMI resins was greater than that of the DBA-BMI resins, with an initial thermal decomposition temperature of 428 °C and a glass transition temperature of 285 °C. The excellent anti-flammability of BA-BHDB-BMI may be attributed to the superior charring capacity of BA-BHDB, which contributes to the formation of a dense and protective char layer during thermal decomposition.
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APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
·
2022
·Vol. 106
·期 7
·2619-2636
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IF 5.56
Chen Yunni,Xu Chenglong,Yang Huilin,Liu Zhenying,Zhang Zhibin,Yan Riming,Zhu Du
Abstract Perylenequinones (PQ) are natural polyketides used as anti-microbial, -cancers, and -viral photodynamic therapy agents. Herein, the effects of L-arginine (Arg) on PQ biosynthesis of Shiraia sp. Slf14(w) and the underlying molecular mechanism were investigated. The total content of PQ reached 817.64 ± 72.53 mg/L under optimal conditions of Arg addition, indicating a 30.52-fold improvement over controls. Comparative transcriptome analysis demonstrated that Arg supplement promoted PQ precursors biosynthesis of Slf14(w) by upregulating the expression of critical genes associated with the glycolysis pathway, and acetyl-CoA and malonyl-CoA synthesis. By downregulating the expression of genes related to the glyoxylate cycle pathway and succinate dehydrogenase, more acetyl-CoA flow into the formation of PQ. Arg supplement upregulated the putative biosynthetic gene clusters for PQ and activated the transporter proteins (MFS and ABC) for exudation of PQ. Further studies showed that Arg increased the gene transcription levels of nitric oxide synthase (NOS) and nitrate reductase (NR), and activated NOS and NR, thus promoting the formation of nitric oxide (NO). A supplement of NO donor sodium nitroprusside (SNP) also confirmed that NO triggered promoted biosynthesis and efflux of PQ. PQ production stimulated by Arg or/and SNP can be significantly inhibited upon the addition of NO scavenger carboxy-PTIO, NOS inhibitor N ω -nitro-L-arginine, or soluble guanylate cyclase inhibitor NS-2028. These results showed that Arg-derived NO, as a signaling molecule, is involved in the biosynthesis and regulation of PQ in Slf14(W) through the NO-cGMP-PKG signaling pathway. Our results provide a valuable strategy for large-scale PQ production and contribute to further understanding of NO signaling in the fungal metabolite biosynthesis. Key points • PQ production of Shiraia sp. Slf14(w) was significantly improved by L-arginine addition. • Arginine-derived NO was firstly reported to be involved in the biosynthesis and regulation of PQ. • The NO-cGMP-PKG signaling pathway was proposed for the first time to participate in PQ biosynthesis.
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PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2026
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IF 12.5
Haiyang Wang,Le Guo,Jiaxing Li,Chi Zhang,Yuxiang Gao,Jiaqi Ma,Jiabao Xiong,Siyu Huang,Qinfen Wu,Jingtao Wang,Yaqi Cui,Biao Dong,Nuernisha Alifu
cRGD-modified ITC NPs target αvβ3 integrin for BBB/BTB traversal in GBM. • NIR-triggered ITC NPs combine TMZ chemotherapy and phototherapy. • ITC NPs generate NO in situ to improve perfusion and modulate resistance. • NIR-II fluorescence imaging and LSCI enable GBM diagnosis and perfusion monitoring. Glioblastoma (GBM) remains one of the most lethal brain malignancies, largely due to the blood-brain barrier (BBB) and the pathologically heterogeneous blood-tumor barrier (BTB), which severely restrict drug delivery. To achieve targeted BBB/BTB traversal, we developed cRGD-modified ICG/TMZ@Lips nanoparticles (ITC NPs). The nanoplatform actively targets αvβ3 integrin overexpressed on tumor endothelial cells and GBM cells, thereby promoting receptor-mediated transport and tumor penetration. Under near-infrared (NIR) irradiation, ITC NPs trigger temozolomide (TMZ) release and photo-responsive NO-associated effects. These effects are accompanied by heat shock protein 70 (HSP70) downregulation and modulation of resistance-related pathways, which may contribute to enhanced chemosensitivity. Furthermore, we integrated near-infrared II (NIR-II) fluorescence imaging with laser speckle contrast imaging (LSCI) for real-time GBM diagnosis and perfusion monitoring. To the best of our knowledge, among existing BBB/BTB traversal strategies, this is the first study to apply cRGD peptide for specific and efficient BBB/BTB penetration in GBM therapy. This strategy directly addresses the fundamental limitations imposed by the heterogeneous and efflux-active BTB, offering a precise nanomedicine approach for improved therapeutic outcomes. Download: Download high-res image (353KB) Download: Download full-size image
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2026
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IF 9.1
Liuqing Yang,Zhuoting Xiong,Haowen Zou,Bin Zhao,WingKei Ho,Dingze Lu
Improving the efficiency of nitric oxide (NO) removal while reducing the formation of toxic nitrogen dioxide (NO 2 ) is a challenge. Nonetheless, it remains uncertain regarding the distinct roles of carbon versus nitrogen vacancies in graphitic carbon nitride (g-C 3 N 4 ) in governing the oxidation pathway. In this study, g-C 3 N 4 enriched with carbon or nitrogen vacancies, along with the corresponding polyvinylidene fluoride (PVDF)-supported composite films, are prepared. The adsorptions and anchoring of NO and its intermediates are significantly enhanced by the carbon vacancies. Despite a high free energy barrier of the conversion from nitrite to nitrate, the strong anchoring suppresses the release of gaseous NO 2 . The formation of Nitrogen vacancies gives rise to polarization of the spin, leading to a significant negative displacement of the potential of the conduction band and increased carrier lifetime along with a considerable decrease in the barrier for the conversion of nitrite to nitrate. This mechanism leads to enhanced reaction flux that will improve deep oxidation. The incorporation of these materials into the PVDF film greatly enhances performance and provides reusability. This work elucidates the distinct mechanisms by which carbon and nitrogen vacancies regulate NO oxidation, providing a theoretical basis for designing efficient and selective air purification materials.
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高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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2026
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IF 16.8
Zhaoqi Zhang,Qian Ji,Hongfei Zhang,Heng Liu,Lei Zhao,Mengna Zhang,Lu Chen,Qian Li,Shaokang Guan
Poly(TA-Arg) coating with self-supplying NO fabricated via ethanol-water system. • Poly(TA-Arg) sample possesses a low degradation rate. • HA@CS nanoparticles synthesized with optimal HA:CS ratio. • HA@CS sample promotes endothelialization via PI3K-Akt-eNOS and Nrf2 pathways. Rapid degradation and inadequate re-endothelialization hinder the clinical application of biodegradable magnesium (Mg) alloy stents, while thrombosis and bacterial colonization further compromise early implant performance. To address these challenges, a hierarchical bilayer coating, consisting of an inner poly(α-thioctic acid)-L-arginine (Poly(TA-Arg)) layer and an outer hyaluronic acid/chitosan (HA@CS) nanoparticle layer (particle size, ∼240 nm), was fabricated on a fluorinated ZE21B Mg alloy. The Poly(TA-Arg) layer supported endothelial cell (EC)-mediated endogenous nitric oxide (NO) production. It also provided strong interfacial adhesion and corrosion protection, reducing the corrosion current density to 5.60 × 10 −8 A cm −2 . The HA@CS layer exhibited antioxidant activity, prolonged clotting time, low hemolysis, and > 99% antibacterial efficacy, as determined by plate counting. The bilayer coating promoted EC proliferation while inhibiting smooth muscle cell growth. RNA sequencing suggested that the pro-endothelialization effect was associated with PI3K-Akt- endothelial nitric oxide synthase-related signaling and an Nrf2-related antioxidant response. In a rat abdominal aorta model, the coated wire was surrounded by a thin, well-organized neointima with endothelial coverage, minimal inflammation, and no evident thrombosis. No obvious histopathological abnormalities were observed in major organs, and hematological parameters remained within normal ranges. This multifunctional coating provides a potential strategy for improving the vascular compatibility of biodegradable Mg stents. Download: Download high-res image (332KB) Download: Download full-size image
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高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2026
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IF 5.1
Huiyun Xia,Zeliang Wu,Kaixuan Fan,Lifang Song,Sen Huang,Meiqi Yang
In response to the problem of nitrogen oxide pollution in tunnel environments, this study successfully prepared I - doped Bi 2 O 2 CO 3 photocatalyst I-BOC through solid-phase grinding method. The introduction of I - leads to a notable reduction in the bandgap of BOC, while also enhancing the specific surface area and pore volume, thereby facilitating the effective separation of photogenerated carriers. When exposed to visible light, I-BOC demonstrates a peak degradation efficiency of 58% for NO, and experiments involving free radical capture indicate that ·O 2 – is the primary active species, and explore the impact of the tunnel environment on the degradation efficiency of the catalyst. Additionally, epoxy resin served as the substrate for film formation, and 1H, 1H, 2H, 2H-perfluorodecyltrimethoxysilane (PFDTES) was incorporated as a low surface energy additive. A superhydrophobic photocatalytic self-cleaning coating (FBIE) characterized by a micro-nano rough structure was created using a one-step spraying technique. This coating showcases outstanding superhydrophobic properties and water contact angle exceeding 150°, along with excellent mechanical durability and chemical stability, achieving a visible light degradation efficiency of up to 65% for NO, and outstanding physical and chemical self-cleaning ability. By exploring the catalytic effects of I-BOC and FBIE coatings under different humidity conditions, the synergistic mechanism of coating photocatalysis and self-cleaning is revealed, providing broad application prospects for coatings in tunnel air purification.
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高影响因子
Journal of Environmental Sciences
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2026
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IF 6.5
Su Jiang,Jun Tang,Pengling Zhang,Lingkui Zhao,Junfeng Zhang,Yan Huang
NH 3 rapidly attenuates photo-assistance efficiency in co-removal of NO and toluene. • NO 2 formation/consumption is rate determining step of photothermal SCR reaction. • Dispersed V 5+ =O sites oxidize both NH 3 , NO and toluene under illumination. • NH 3 -derived radicals attack aromatic rings, inducing phenolic buildup on active sites. • Without mitigating photo-assisted effect attenuation, photothermal deployment increases burdens. V 2 O 5 /TiO 2 -mediated photothermal co-removal of NO and VOCs from incineration flue gas represents a promising energy and emission saving strategy. It is crucial to elucidate the effect of V 2 O 5 loading and to clarify the interaction among reactants during the photothermal catalytic process. Herein, this study elucidates the V 2 O 5 loading effect and provides mechanistic insight into reactant interactions over V 2 O 5 /TiO 2 during photothermal co-removal of NO and toluene. Optimal V 2 O 5 loading increases dispersed V 5+ =O redox and V 5+ –OH adsorption activation sites, while Ti-O-V interfacial motifs modulate the local electronic structure to promote interfacial charge transfer and charge separation. Under photothermal conditions, V 5+ =O sites simultaneously mediate the oxidation of NH 3 and NO, where the formation and consumption of NO 2 serves as the rate-determining step, leading to ineffective accumulation of photogenerated NH 4 + species. In the absence of NH 3 , photogenerated charge carriers promote the initial dehydrogenation of toluene via side-chain activation on V 5+ -OH sites, followed by deep ring-opening degradation mediated by V 5+ =O species. NO reduces the overall toluene conversion but enhances the reaction selectivity toward deep oxidation. When NH 3 and toluene co-exist, radicals derived from NH 3 directly attack the aromatic ring, thereby changing the side-chain oxidation pathway, triggering the formation of strongly adsorbed phenolic intermediates that block catalytic sites. NH 3 does not merely compete with toluene for V-OH adsorption sites, its presence also redirects the toluene oxidation pathway and locks the reaction into a thermally driven regime. This work provides insights into the V 2 O 5 -loading effects and the interaction of reactants in multipollutant photothermal catalysis. Download: Download high-res image (337KB) Download: Download full-size image
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高影响因子
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
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2026
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IF 4.4
Tong Zhou,Ya Li,Xiaolong Lian,Jingjing An,Linyan Deng,Meng Xia,Yufeng Gong,Ningbo Geng,Qiliang Chen
Life-cycle exposure to environmentally relevant DPhP did not cause overt reproductive impairment in zebrafish. • DPhP exposure increased female GSI and mature oocyte count but did not affect sex hormone levels. • DPhP exposure downregulated fshβ in female brain while other HPG axis genes showed no significant changes. • Parental DPhP exposure had no significant transgenerational effects on F₁ offspring. Diphenyl phosphate (DPhP) is widely detected in environmental matrices, yet its reproductive toxicity following chronic exposure remains poorly understood. This study investigated the reproductive toxicity of life-cycle exposure to environmentally relevant concentrations of DPhP in zebrafish. Embryos (2 h post-fertilization) were exposed to DPhP at measured concentrations of 0.8, 3.9, or 35.6 μg/L for 120 days, covering the entire life cycle from embryo to adult. Reproductive endpoints assessed in adults included gonadosomatic index (GSI), gonad histopathology, reproductive performance, sex steroid hormone levels, expression of key genes along the hypothalamic-pituitary-gonadal (HPG) axis, and F₁ generation development. Exposure to 3.9 or 35.6 μg/L DPhP significantly increased GSI in females but not in males. Although no overt histopathological changes were detected in the gonads, females exposed to 35.6 μg/L DPhP showed a significant increase in the number of mature oocytes in the ovaries. Cumulative egg production over 21 days showed an increasing trend that did not reach statistical significance. In females, DPhP exposure significantly downregulated fshβ expression in the brain. However, at all tested concentrations, no significant changes were observed in other HPG axis-related genes or in plasma sex steroid hormone levels in either sex. Furthermore, no significant effects were found on hatching rate, survival rate, heart rate, or body length of F₁ offspring. Collectively, life-cycle exposure to DPhP within the tested concentration range exerts limited effects on the reproductive endocrine system of zebrafish and does not induce overt reproductive impairment. Download: Download high-res image (160KB) Download: Download full-size image
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高影响因子
Food Bioscience
·
2026
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IF 6.2
Shiyu Zhang,Xinzhuan Yao,Yanxia Wang,Muhammad Safiullah Virk,Shiyu Tian,Zhenkedai Yuan,Qihong Zou,Linlin Li,Shenyuan Ye,Hu Tang,Litang Lu
This study comprehensively evaluated Baiye No.1 (BY1H), a temperature-sensitive tea cultivar. Normally, it whitens in early spring and gradually regreens in autumn, accompanied by declining free amino acids and rising catechin and caffeine levels. We reevaluated the common belief that autumn tea is inferior. The feasibility of producing premium yellow tea from autumn-harvested BY1H was assessed, and the mechanisms underlying its quality formation were elucidated. The menhuang yellowing step played a central role. Driven by non-enzymatic thermal oxidation and hydrolysis, it reduced typical autumn defects by lowering phenolic and caffeine levels and increasing sweet-tasting free amino acids. Sensory evaluation, targeted metabolite profiling, and multivariate statistics were integrated to compare BY1H with four reference yellow teas (Ya’an Yellow Tea, Weishan Maojian, Yuan’an Luyuan Yellow Tea, and Pingyang Huangtang). BY1H yellow tea exhibited superior sensory attributes for its mellow-sweet taste and layered floral bouquet. Chemically, this profile was supported by a high water-extract yield, low levels of caffeine and ester-catechins, and abundant serine and phenylalanine. Together, these components contributed to its mellow-sweet taste. Gas Chromatography-Mass Spectrometry (GC-MS) analysis further identified 18 key volatiles, among which benzaldehyde, β-ionone, and methyl 2-(2-methylpropoxy)benzoate were the major contributors to the sweet-floral aroma. Partial Least-Squares Discriminant Analysis (PLS-DA) and Mantel tests confirmed BY1H’s unique chemical signature, clearly separating it from the other traditional yellow teas. These findings demonstrate that autumn BY1H leaves can be valorized through yellow tea processing, providing a scientific basis for cultivar innovation and sustainable utilization of seasonal tea resources.
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危险品化学品经营许可证（带存储）