NEUROENDOCRINOLOGY LETTERS
·
2024
·
IF 0.6
Xiumei Cheng,Xinyi Cao,Yichun Yang,Lingxiao Wang,Yuxuan Yang,Yunjian Pan,Yongliang Zheng,Churong Wei,Yougen Luo
Objective: Methylmercuric chloride (MMC) has neurotoxicity, while hydrogen sulfide (H2S) has shown inhibitory properties against nerve damage induced by various factors. The study aimed to investigate the impact of H2S on MMC-induced learning and memory impairment in mice and to explore the underlying mechanisms. Methods: A mouse model of learning and memory impairment was established by MMC gavage, and sodium hydrosulfide (NaHS) was used as an H2S donor for intervention. Cell viability and live/dead cell ratio in HT22 neuronal cells were assessed by CCK-8 assay and Calcein/PI staining, respectively. The Morris water maze test was performed to evaluate the learning and memory abilities of mice. Western blotting was utilized to determine protein expressions of BDNF and TrkB. The effects of H2S on MMC-induced learning and memory impairment were investigated based on the BDNF/TrkB pathways. Results: (1) MMC treatment decreased cell viability and reduced the ratio of live cells in HT22 cells, while H2S reversed these changes. (2) MMC prolonged escape latency, decreased platform crossing frequency, and reduced quadrant distance percentage of the platform in the Morris water maze test, while H2S reversed the above changes. (3)MMC downregulated BDNF and TrkB expression levels, while H2S suppressed these changes induced by MMC. (4)Treatment with 7, 8-DHF (a TrkB agonist) significantly attenuated MMC-induced prolonged escape latency and reduced platform crossing frequency. Conclusions: Our findings demonstrated that H2S ameliorated learning memory deficits in mice by reversing the inhibitory effects of MMC on BDNF/TrkB signaling pathway.
研究领域:
神经科学
·
毒理学
✓ 已验证
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2020
·
IF 6.551
Haiying Wang,Tao Yuan,Lei Huang,Yingjie He,BiChao Wu,Lanjing Hou,Qi Liao,Weichun Yang
Heteroatoms doping is an important modification method in carbon electrode for CDI technology . In this study, a new facile approach of homogeneous phosphorus doping in carbon matrix was proposed via crosslinking polymerization of m -phenylenediamine and phytic acid. The carbonized composites (NPC) showed the characteristics of phosphorus/nitrogen co-doping with excellent hydrophilicity, high electrochemical performance, lower inner resistance and good cycling stability, far beyond that of carbon without phosphorus doping. Compared with reported similar materials and commercial carbon, the chloride adsorption capacity of NPC used as electrode for deionization capacitors was significantly improved (21.4 mg g −1 in a 500 mg L −1 Cl − solution at 1.2 V). Particularly, based on the charge distribution analysis of phosphorus doping in carbon matrix by using Material Studio calculation, the possible enhanced dichlorination mechanism of the carbon composites as electrode for deionization capacitors was carefully explored. The phosphorus/nitrogen co-doped carbon displayed a promising prospect for chloride removal in the application of CDI technology.
研究领域:
材料科学
·
环境工程
·
电化学
✓ 已验证
DOI
PubMed
高影响因子
DYES AND PIGMENTS
·
2019
·
IF 4.018
Shu Wang,Shun-Hua Wu,Wen-Le Fang,Xiao-Feng Guo,Hong Wang
A facile and straightforward strategy was used to prepare carbon dots (CDs) using catechol as carbon source in one-pot hydrothermal method . The synthesis method is simple without any doping and modification and the prepared CDs do not require any post-processing. Characterizations of the obtained CDs indicated that they had high crystallinity and higher quantum yield (QY, 32%) than most non-functionalized and non-doped CDs. Noticeably, the fluorescence of CDs could be quenched with hypochlorite (ClO − ) by oxidation of the residual pyrocatechol groups on the surface to o -benzoquinone exhibiting high sensitivity and selectivity for ClO − . The assay covered a linear range from 0.1 to 10 μM with a low detection limit of 30 nM. The results showed that the CDs provided a promising potential tool for the detection of ClO − in real water samples.
研究领域:
材料科学
·
环境科学
·
分析化学
✓ 已验证
DOI
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2021
·
IF 7.963
Ran Yang,Jun Cai,Hu Yang
Zero-valent aluminum (ZVAl) is a promising reductant because of its relatively low redox potential , which can efficiently activate molecular oxygen to generate reactive oxygen species . However, its long-term performance is limited by the intrinsic dense oxide layer and the passivation effect of the accumulative Al-(hydr)oxide on its surface during the reaction. In this study, four clay minerals with different compositions were mixed with ZVAl by ball milling to obtain four composites of ZVAl and clay (ZVAl-Clay), which were used to degrade a high concentration of 4-chlorophenol (4-CP) under ambient conditions. The oxidation efficiencies of different ZVAl-Clays were strongly relevant to Fe contained in the clay minerals. The Fe-free ZVAl-Clay presented poor oxidation performance, whereas the reaction efficiencies of those ZVAl composites with Fe-bearing clays exhibited varying degrees of improvement. In comparison with the original ZVAl, the highest oxidation rate increased by 23 times, the maximum increased OH production was approximately 8 times, and the corresponding mineralization efficiency improved by 38.7%. However, the levels of improved oxidation performance of various ZVAl-Clays were not positively correlated with their actual total Fe contents, and their degradation efficiencies might also be affected by other physical and/or chemical properties of different clays. The synergistic mechanism revealed by various characterizations was that electron transfer might occur from ZVAl to the structural Fe(III) of the clay through the basal plane or edge of clays triggered by ball milling. Thus, the partially produced Fe(II) on the clay surface promoted the Fenton-like reaction to decompose H 2 O 2 into OH for efficient oxidation of 4-CP. In short, the ZVAl composites with Fe-bearing clays deserved further exploration as potential materials for efficient degradation of organic matters in wastewater samples.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
ENVIRONMENTAL POLLUTION
·
2023
·
IF 8.9
Fanfan Ju,Liuzhu Chen,Teng Ma,Xiaoli Wang,Zhanqiang Chen,Jiejun Zheng,Xinxing Xia
Studying the geochemical behavior of chlorine is the basis of understanding the chlorine cycle in nature. To explore the spatiotemporal distribution of natural organic chlorine (Cl org ), L layer (litter fall), F–H layer (humification zone), topsoil layer (0–20 cm), and deep soil layer (20–40 cm) samples were collected from 18 sampling sites at different altitudes (851–2918 m) in Shennongjia Forest in May, August, and December. Cl org content was analyzed, and the Cl org stocks were calculated. The major factors affecting the distribution of Cl org were explored. The results revealed that the sum of Cl org content in four layers varied from 7.958 to 184.686 mg/kg, and the highest value was observed in August. Cl org accounted for 46%–77% of total chlorine, with the highest mean ratio in soil layer (0–20 cm). Cl org content exhibited the following trend: F–H layer > L layer > topsoil layer (0–20 cm) > deep soil layer (20–40 cm). The seasonal patterns of Cl org in soil layers were different from that in L and F–H layers, which were mainly controlled by the content and humification degree of organic matter. Cl org storage was much higher in soil layers (61–246 kg/ha) than those in F–H layer (1.1–7.1 kg/ha) and in L layer (0.1–0.8 kg/ha) because of the large thickness of the soil layers. Overall, the Cl org content exhibited an increasing trend with altitude, except at an altitude of approximately 1800 m. Cl org content in L and F–H layers varied more obviously with altitude than that in soil layers. When inorganic chlorine (Cl in ) was not a limiting factor for the chlorination process, Cl org content in L and F–H layers was significantly affected by climate and organic matter controlled by altitude, while Cl org content in soil layers was also mediated by metal ions and pH, and soil particle size. This study could provide a scientific basis for assessing the chlorine cycle in nature.
研究领域:
环境科学
·
土壤学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF FLUORESCENCE
·
2022
·Vol. 33
·期 2
·575-586
·
IF 2.525
Zhou Boxin,Han Yunlong,Liu Jingyu,Cheng Kai,Dong Mingdong,Tang Xu
Hypochlorite is an important biological reactive oxygen species, which plays a pivotal role in various life activities. Excessive presence in the human body or excessive intake in life causes a series of diseases. To monitor the hypochlorite level in living cells, organisms and environment water samples, we herein designed and synthesized three organic small molecule fluorescent probes with different recognition sites based on nitrile biphenyl. Through performance comparison, it was found that probe A-HM exhibited the best detection performance for hypochlorite with a low detection limit of 2.47 × 10 –6 M. The introduction of hypochlorite will induce probe fluorescence A-HM to turn on, and the fluorescence colour will change from colourless to green. The application of A-HM in biological systems has been demonstrated by the imaging monitoring of hypochlorite in MCF-7, L929 cells and zebrafish. Furthermore, A-HM was also used for the accurate determination of the hypochlorite level in real water samples with high sensitivity and good recoveries.
研究领域:
分析化学
·
生物化学
·
环境科学
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2017
·
IF 6.216
Ping Chen,Qianxin Zhang,Yuehan Su,Lingzhi Shen,Fengliang Wang,Haijin Liu,Yang Liu,Zongwei Cai,Wenying Lv,Guoguang Liu
A visible light-driven and environmentally compatible photocatalyst is considered to be a potential application for wastewater treatment processes. In the present study, we employed carbon quantum dots (CQDs) to modify BiOCOOH with the aim of negating the UV limit of the photocatalyst, while increasing its photocatalytic activity. The structure, morphologies, and other characteristics of CQDs/BiOCOOH composites were investigated, which confirmed that CQDs were successfully coupled with BiOCOOH. Under visible light irradiation, a very low CQDs content of 2.0% weight resulted in a 4.64-fold more rapid reaction rate in the photodegradation of diclofenac (DCF) than pristine BiOCOOH. The CQDs served to enhance the visible light absorption of BiOCOOH, which significantly improved visible-light harvesting, as well as interfacial charge transfer and separation. Through a new model study it was revealed that O 2 − was predominantly responsible for DCF degradation. Based on mass spectrometry and theoretical calculations, primary intermediates were identified, and the key pathways proceeded mainly through e − reduction, O 2 − attack, and OH addition reactions. The Vibrio fischeri , Desmodesmus subspicatus , and Daphnia magna were selected to evaluate the acute toxicity, which initially increased and further decreased when the total organic carbon and organic chlorine compounds were reduced. The excellent dechloridation, mineralization, and detoxicity properties via the synthetic CQDs/BiOCOOH photocatalysts clearly demonstrated the potential of this strategy.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2021
·
IF 8.128
Haitao Xu,Dianhua Song,Jiao Li,Yan Zhao,Ruijie Yang,Jingzhe Zhao
The demand for sustainable energy sources urges the development of efficient and earth-abundant electrocatalysts . Herein, chlorine assisted ion-exchange and in-situ sulfurization processes were combined to construct CuCo 2 S 4 @(Cu,Co) 2 Cl(OH) 3 heterostructures from Cu(OH) 2 nanoarrays. Chlorine element in the cobalt source stimulated the formation of (Cu,Co) 2 Cl(OH) 3 precursor, and further facilitated partial transformation of the precursor to CuCo 2 S 4 on the surface to achieve composite structure. The mixed valences of Co element (Co 3+ in CuCo 2 S 4 and Co 2+ in (Cu,Co) 2 Cl(OH) 3 ) and O S interpenetrated nanointerface in the composite catalysts provided low electron transfer resistance for good alkaline oxygen evolution reaction (OER) activities. In 1 mol L −1 KOH electrolyte, the overpotentials of the optimal composite catalyst reached 253 and 290 mV respectively at the current density of 20 and 50 mA cm −2 , which is comparable to the activity of commercial Ir/C (281 mV@20 mA cm −2 ). These findings could provide opportunities for designing effective and inexpensive composite electrocatalysts through nanointerface engineering strategy.
研究领域:
材料科学
·
电化学
·
能源转换与存储
✓ 已验证
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2022
·
IF 7.968
Mingzhu Ren,Jing Wang,Zhengyang Wang,Sihan Sun,Jiakai Qiu,Yanchun Shi,Zhou-jun Wang,Yongbing Xie
Chlorobenzene is a typical toxic and persistent organic pollutant in wastewater and site polluted groundwater. In this study, powdered activated carbon (AC) was used for the adsorption of chlorobenzene from simulated wastewater, and it showed high adsorption capacity in a wide range of pH. Pseudo-second-order kinetic model and Langmuir isothermal adsorption model are suitable to describe the adsorption process . Furthermore, the adsorption mechanism is clarified by correlating the adsorption rate constants with the molecular descriptor by theory calculating. Chlorobenzene adsorption on AC was mainly controlled by π-π interaction and hydrophobicity , external mass transfer and intraparticle diffusion. Ozonation was adopted to regenerate the adsorption saturated AC and simultaneously avoid secondary solid waste. After three cycles of adsorption-ozonation, the adsorption capacity of AC even increased from 80 to 215 mg/g due to the increase of oxygen-containing functional groups on the AC surface. This mode can also be used for granular AC column adsorption, and ozonation partially restored the adsorption capacity. The work provides a better alternative way to deal with chlorobenzene polluted wastewater and groundwater.
研究领域:
环境科学
·
化学工程
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2024
·Vol. 31
·期 15
·22917-22924
·
IF 0
Liu Xunyue,Zhu Haojie,Song Wenyang,Rao Qiong,Xu Xiaoxiao
Chloramphenicol, a broad-spectrum antibiotic employed for controlling bacterial infections, presents an intriguing aspect in terms of its environmental fate in soils. 14 C-labeled chloramphenicol was used to explore its mineralization and residue characteristics in three distinct agricultural soils in China. The findings revealed a nuanced pattern in the fate of 14 C-chloramphenicol, with notable variations among the different soils under investigation. The chloramphenicol extract residue exhibited a reduction of 18.04% in sandy clay soil, 23.04% in clay loam soil, and 21.73% in loamy clay soil. Notably, the mineralization rate in sandy clay soil was 25.22% surpassed that in the other two soils, particularly during the initial stages of incubation. Over time, the diminishing extract residue underwent conversion into minerals and bound residue. The formation rate of bound residue was increased from 44.59 to 53.65% after adding 10% manure, suggesting that chloramphenicol easily binds with soils rich in organic matter. The bound residue is predominantly localized in the humin fraction across all soils. Additionally, the sterilized soil experiments indicated the pivotal role of microorganisms in influencing the fate of chloramphenicol under the specified experimental conditions. In conclusion, this study offers valuable insights into the environmental dynamics of chloramphenicol in soils, emphasizing the importance of soil composition, organic matter content, and microbial activity. The findings contribute to a scientific understanding of the environmental safety implications associated with chloramphenicol usage.
研究领域:
环境科学
·
土壤学
·
微生物学
·
药理学
·
农业化学
✓ 已验证
DOI
Journal of Materials Chemistry C
·
2020
·Vol. 8
·期 38
·13336-13341
·
IF 7.059
Gaoping Xu,Leipeng Zhang,Bo Wang,Zichen Ren,Xi Chen,Shuliang Dou,Feifei Ren,Hang Wei,Xiaobai Li,Yao Li
Flexible polyaniline films doped by H2SO4–HClO4 multiple acids were synthesized, and for the first time, their electrochromic mechanism was studied via optical characterizations from the aspects of polarons and roughness. The electrochromic device based on the doped polyaniline films as the active material exhibits Δε of 0.47 in 8–14 μm and reflectivity higher than 80% in 250–400 nm, which can be integrated with the white snow environment in the UV-vis-infrared spectroscopy due to the sunlight scatter from the abundant micropores. In addition, the device exhibits a superior fast electrochromic behavior and stability of more than 200 cycles without compromising its performance. More importantly, the finite-element method and experimental results demonstrate that the device can achieve thermal management upon flat and twisted configuration. The flexible device shows promise for a broad range of potential applications in optical and thermal regulation systems.
研究领域:
材料科学
·
光学工程
✓ 已验证
DOI
高影响因子
Applications in Energy and Combustion Science
·
2023
·
IF 0
Cao Kuang,Mumin Rao,Xiangbo Zou,Jinchen Ma,Ji Ye,Shiwei Qin,Gongda Chen,Shuzhong Wang,Jun Zhao
This effort is to investigate three different Cu-based oxygen carriers (OCs) with polyvinyl chloride (PVC) and coal in chemical-looping combustion (CLC). The combustion process and synergetic analysis of PVC with coal were evaluated. There were four stages in the reaction of OCs with PVC, which HCl released from PVC could react with OCs at about 200–400 °C. CuO and CuO modified by limestone showed better immobilization of chlorine while CuO modified by iron ore and chrysolite inhibited the reaction of HCl with CuO. PVC char combustion temperature started at about 500 °C which were lower than that of coal char. The combustion efficiency of PVC CLC was all above 92%, except using Cu-Fe as OC which was about 88%. The presence of ZD in PVC showed positive effect on every stage. The addition of coal inhibited the reaction of HCl with CuO. The presence of PVC in ZD reduced the temperature of coal char and the addition of ZD in PVC increased the reaction rate. The synergistic effect was obvious between the PVC and coal blends which is beneficial for the complete combustion in solid fuel CLC
研究领域:
能源与燃料
·
环境科学
✓ 已验证
DOI
危险品化学品经营许可证（带存储）