ACS Applied Polymer Materials
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2024
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IF 4.4
Cijun Shuai,Xingming Long,Binxin Sun,Tiantian He,Xiong Shuai,Guoyong Wang,Shuping Peng
Bacterial infection is a severe challenge faced by artificial bone transplantation, which might cause delayed bone healing or even transplant failure. Photodynamic therapy (PDT) has garnered widespread attention as a treatment for infections due to its noninvasiveness, few side effects, and high spatiotemporal selectivity. Nevertheless, owing to the bacterial membrane obstacle, it is difficult for exogenous reactive oxygen species (ROS) to penetrate into bacteria, which leads to an unsatisfactory antibacterial effect. Herein, a heterojunction of Ti2C3 nanosheets/tin disulfide (MXene/SnS2) is designed, which integrates photothermal and photodynamic properties. Then, MXene/SnS2 was incorporated into a poly-l-lactic acid powder (PLLA) matrix to fabricate an artificial bone scaffold with selective laser sintering (SLS) technology. Under near-infrared laser irradiation, SnS2 can strengthen the near-infrared light absorption of MXene to generate local hyperthermia, thus enhancing bacterial membrane permeability. Meanwhile, MXene/SnS2 enhances charge transfer and inhibits electron–hole pair separation, thereby generating more ROS that can penetrate the bacterial interior. The results indicated that this antibacterial strategy has effective antibacterial activity, and the antibacterial rate reached over 90%. Overall, this research presents an attractive antibacterial strategy for implant-related infection.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
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IF 8.5
Zhongwen Su,Yonggang Peng,Ying Yu,Yujing Zhong,Junyue Zeng,Yikai Chen,Sekar Vijayakumar,Yangfan Mao,Lin Wang,Meihua Xin,Mingchun Li
Chitosan, a renewable resource, is increasingly studied for its food packaging applications. In this study, chitosan (CS) was used as a raw material to synthesize two derivatives—dodecyl chitosan quaternary ammonium salt (DMDBC) and triphenyl chitosan quaternary phosphonium salt (TPPBC). These were combined with polyvinyl alcohol (PVA) to develop a multifunctional food packaging material with enhanced physical, antibacterial, and antioxidant properties. The resulting composite films exhibited excellent homogeneity and biocompatibility. Strong intermolecular hydrogen bonding among DMDBC, TPPBC, and PVA was confirmed, contributing to the amorphous structural characteristics of the films. Among the various formulations, the film containing 6 % tartaric acid (6 % TA-C12) demonstrated the best mechanical strength, water vapor barrier, and oxygen barrier properties. Incorporation of DMDBC and TPPBC endowed the films with remarkable bioactivities, achieving DPPH and superoxide radical scavenging rates of 81.2 % and 35.6 %, respectively, along with inhibition zone diameters of 32.3 mm ( S. aureus ) and 29.5 mm ( E. coli ). Compared to commercial polyethylene (PE) films, the developed films effectively delayed spoilage and extended the shelf life of strawberries by up to nine days. These high-performance composite films hold strong potential as sustainable alternatives to conventional PE packaging materials in the field of fruit preservation.
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ADVANCED MATERIALS
·
2025
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IF 26.8
Ran Wang,Yu Cheng,Qiran Zhang,Haoran Li,Yangyang Wang,Jiaqi Liu,Ruirui Xing,Jinming Ma,Tifeng Jiao
With the development of artificial intelligence and the Internet of Things, non-contact sensors are expected to realize complex human-computer interaction. However, current non-contact sensors are mainly limited by accuracy and stability. Herein, an intelligent infrared photothermal non-contact sensing system is developed that provides long-distance and high-accuracy non-contact sensing. A black phosphorus (BP)-based composite organogel is designed, which exhibits excellent photothermal properties and environmental stability, as the active material. This material can detect patterns created by near-infrared (NIR) light through various patterned masks monitored by an infrared thermal imager. The constructed non-contact sensing system is capable of accurately recognizing 26 letters with an impressive accuracy rate of 99.4%. Furthermore, even small size non-contact sensors can maintain high sensitivity and stability across a wide temperature range, at long working distances, and under different current intensities and dark conditions, demonstrating exceptional robustness. Combined with machine learning method, it is demonstrated that the non-contact sensing system excels in pattern recognition and human-computer interaction. These features highlight its potential applications in intelligent robotics and remote control systems.
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ACS Sustainable Chemistry & Engineering
·
2025
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IF 7.3
Chang-Wei Zhang,Jian-Zhong Ye,Xing-Ying Xue,Wen-Jun Li,Hong-Xia Chen,Cheng-Zhang Wang
Baphicacanthus cusia (B. cusia) was traditionally used as raw material to prepare indigo naturalis; however, many factories have been shut down by local governments on account of their serious pollution contributions. In this study, a green and sustainable production of B. cusia leaf extracts is proposed. Namely, new indigo extract (NIE) and phenolic acid extract (PAE) were produced in an integrated fashion by enzyme transformation coupled membrane separation and freeze-drying technologies. The small-scale process was optimized, and its feasibility was verified by a pilot experiment. Moreover, the physicochemical properties, dyeing effect, and wound-healing ability of the two extracts were systematically evaluated. The NIE could be obtained within 1 day and exhibited more than 20 times the indigo content and 1.8 times the pure indigo yield than indigo naturalis. Moreover, the NIE showed superior dye-uptake rate and washing and rubbing fastness on pure cotton poplin compared with natural indigo from India. The PAE exhibited excellent broad spectrum antibacterial activities, especially S. aureus (IC50 = 32 μg/mL). Significantly, the PAE had no toxicity and presented over 98% of the wound-healing rate on mice by increasing their collagen fiber content. All of above work is of great significance for the extension and sustained healthy development of a B. cusia industry chain.
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ACS Sustainable Chemistry & Engineering
·
2025
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IF 7.3
Yequan Sheng,Xuan Wu,Jing Qi,Guijiang Wang,Cheng Dong,Xueqing Liu,Yanqing Wang,Chenhuan Lai,Xin Tan
This study presents a novel, cost-effective strategy employing nucleophilic polymers as direct additives during dilute acid (DA) pretreatment (2% H2SO4, 170–180 °C) to enhance the bioconversion efficiency of various lignocellulosic biomasses, including poplar (PP), mulberry branches (MB), and corn stover (CS). Screening among nine nucleophilic polymers identified carboxymethyl chitosan (CMS) and gelatin (GE) as exceptional dual-function enhancers to improve both prehydrolysate fermentability and enzymatic hydrolysis yield of pretreated substrates. The addition of CMS in pretreatment significantly detoxified prehydrolysates by reacting with key carbonyl inhibitors (reducing furfural by 19.8–38.6%, 5-hydroxymethylfurfural (HMF) by 3.8–59.1%, vanillin by 16.1–34.2%, syringaldehyde by 15.8–48.2% vs DA prehydrolysate controls). The addition of CMS dramatically boosted the fermentability of prehydrolysates with Saccharomyces cerevisiae, elevating ethanol yields to 7.33 (MB), 6.86 (CS), and 8.36 g/L (PP) from 6.28, 1.66, and 6.95 g/L in DA controls, respectively. Simultaneously, GE addition profoundly improved the enzyme digestibility of pretreated materials, increasing the 72-h enzymatic hydrolysis yields by 64.82 to 49.94%, 38.71 to 97.83%, and 44.26 to 55.15% for MB, CS, and PP, respectively. The findings from XPS and chemical compositional analyses indicated that the better enzyme digestibility might be related to in situ lignin modification with GE assistance. Crucially, both polymers demonstrated consistent efficacy across diverse feedstocks, with CMS also mildly aiding digestibility and GE contributing to the detoxification of pretreated biomasses. This direct addition approach with nucleophilic polymers enhanced enzyme digestibility and fermentation of pretreated materials concurrently without costly post-pretreatment steps, offering a significant advancement for efficient biofuel production.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
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IF 8.5
Yalin Zhang,Xiaoyue Li,Yanhui Duo,Xiaoyuan Liao,Zongzheng Yang
This study reported a modified hydrothermal solvent method for preparing lignin microspheres (LNSs) with controllable size and morphology by precisely regulating the reaction temperature (160–220 °C). Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) were employed to evaluate the structure, morphological, and dimensional attributes of lignin microspheres, and the synthesis mechanism was discussed. The antibacterial efficacy of the hydrothermally treated lignin microspheres (HTLNSs) was evaluated through phosphate-buffered saline (PBS) culture assays, as well as by assessing nucleic acid and protein leakage, and their inhibitory effect on cell membrane permeability. Among the synthesized samples, HTLNS-180 demonstrated superior bacteriostatic properties, achieving the highest nucleic acid content and bacterial cell permeability post-treatment, suggesting significant bacterial cell wall disruption. Its antibacterial inhibition rate reached 51.0 % against Staphylococcus aureus ( S. aureus ) and 54.3 % against Escherichia coli ( E. coli ). The study provides new insights into the structure-property relationship of lignin-based nanomaterials and their potential in biomedical and antimicrobial applications.
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